Antiparasitaires
Les antiparasitaires sont des composés conçus pour traiter et prévenir les infections parasitaires en inhibant la croissance et la survie des parasites. Cette catégorie comprend une gamme d'agents antiparasitaires destinés exclusivement à un usage en laboratoire et non à la consommation humaine. Ces produits sont essentiels à des fins de recherche, permettant aux scientifiques d'étudier les cycles de vie des parasites, les mécanismes d'action et le développement de la résistance. L'utilisation d'antiparasitaires en laboratoire aide à la découverte et à l'optimisation de nouveaux traitements pour les maladies parasitaires, contribuant aux avancées en parasitologie médicale et vétérinaire. Les chercheurs comptent sur ces produits pour améliorer leur compréhension des infections parasitaires et développer des thérapies plus efficaces.
704 produits trouvés pour "Antiparasitaires"
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GNF179
CAS :<p>GNF179 is an optimized 8,8-dimethyl IP analog.</p>Formule :C22H23ClFN5ODegré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :427.9HAT-IN-8
<p>HAT-IN-8 (Compound 38), a blood-brain barrier-permeable inhibitor of Trypanosoma brucei with an EC50 of 0.18 μM, is utilized in the study of Human African</p>Formule :C14H15F2N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :327.35Nanaomycin A
CAS :<p>Nanaomycin A, a quinone antibiotic, reactivates cancer suppressor genes and inhibits DNMT3B (IC50=500nM).</p>Formule :C16H14O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.28Antitrypanosomal agent 16
<p>Antitrypanosomal agent 16 functions as a potent trypanocide, exhibiting an inhibitory concentration 50 (IC50) of 0.04μM against the T.</p>Degré de pureté :98%Couleur et forme :Odour SolidAntileishmanial agent-21
<p>Antileishmanial agent-21 (compound 4e) functions as an inhibitor of Leishmania pteridine reductase 1 (Lm-PTR1), employing an anti-folate mechanism.</p>Formule :C21H16N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :344.36Alkaline tryptase-IN-1
<p>Alkaline tryptase-IN-1 (compound H-13) is an insecticide that targets alkaline trypsin-like enzymes. It has lethal concentration (LC50) values of 8.72, 13.77, 14.17, 12.96, and 12.35 μg/mL against Schizaphis graminum, Sitobion avenae, Brevicoryne brassicae, Aphis gossypii, Aphis spiraecola, and Myzus persicae, respectively.</p>Formule :C29H33BrN2O2SCouleur et forme :SolidMasse moléculaire :553.55Antimalarial agent 31
<p>Compound 31 (compound 7k) is an orally active inhibitor of Plasmodium falciparum aspartic protease, plasmepsin X (PMX), with antimalarial properties [1].</p>Formule :C36H47N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :585.78Antitrypanosomal agent 17
<p>Compound 17 (Compd 7a) exhibits potent antiamastigote activity, demonstrated by its IC50 value of 0.03 μM against the T. congolense strain IL3000 [1].</p>Degré de pureté :98%Couleur et forme :Odour SolidCinchonidine
CAS :<p>Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.</p>Formule :C19H22N2ODegré de pureté :94.96% - 99.87%Couleur et forme :White PowderMasse moléculaire :294.39Antiparasitic agent-17
<p>Antiparasitic Agent-17 (compound 5u), an orally active antiparasitic, demonstrates inhibition against both Chloroquine-sensitive (Pf3D7) and Chloroquine-</p>Formule :C32H30N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.59Antileishmanial agent-19
<p>Compound F27 (Antileishmanial agent-19) is an antileishmanial compound effective against L.</p>Formule :C22H18N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :386.4Anticancer agent 140
<p>Compound 140 (Compd 3) exhibits potential anticancer and antiparasitic activities [1].</p>Formule :C20H26N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.43SpdSyn binder-1
CAS :<p>SpdSyn binder-1 weakly inhibits malaria by binding to Plasmodium falciparum's spermidine synthase. Used for research.</p>Formule :C21H22N4ODegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :346.43Antileishmanial agent-20
<p>Antileishmanial agent-20 exhibits selectivity against the Leishmania parasite, with IC50 values of 2.8 μM for L.</p>Formule :C15H16N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :300.31ML251
CAS :<p>ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.</p>Formule :C17H13Cl2N3O4SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :426.27Antiparasitic agent-20
<p>Antiparasitic Agent-20 (Compound 1p) exhibits broad-spectrum activity as a parasitic inhibitor, demonstrating efficacy against T.</p>Degré de pureté :98%Couleur et forme :Odour SolidCpNMT-IN-1
<p>CpNMT-IN-1 (Compound 11e) is an inhibitor of N-myristoyltransferase (CpNMT) with an IC50 value of 2.5 μM. It also inhibits the growth of microsporidia, demonstrating an EC50 value of 6.9 μM.</p>Formule :C25H25ClN4O4SCouleur et forme :SolidMasse moléculaire :513.008Antiparasitic agent-26
<p>Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM).</p>Couleur et forme :Odour SolidAntitrypanosomal agent 23
<p>Antitrypanosomal agent 23 is an antiparasitic compound effective against intracellular amastigotes of Trypanosoma cruzi in LLC-MK2 and C2C12 cells, demonstrating activity with IC50 values of 0.10 and 0.11 μM, respectively. It also acts as a weak inhibitor of recombinant Trypanosoma cruzi sialyltransferase (TcTS) with an IC50 of 1.1 mM.</p>Formule :C14H16N4O7Couleur et forme :SolidMasse moléculaire :352.1019Cletoquine
CAS :<p>Cletoquine, Hydroxychloroquine's active metabolite, fights CHIKV, has antimalarial properties, and may treat autoimmune diseases.</p>Formule :C16H22ClN3ODegré de pureté :99.95% - 99.98%Couleur et forme :SolidMasse moléculaire :307.82Emoquine-1
<p>Emoquine-1 is a potent orally active antimalarial agent effective against various drug-resistant Plasmodium strains, including artemisinin-resistant dormant parasites. It demonstrates efficacy against proliferative malignant Plasmodium with an IC50 value ranging from 20 to 55 nM. Emoquine-1 holds potential for treating Plasmodium strains resistant to artemisinin combination therapy (ACT), with the capability to eradicate persistent parasites.</p>Formule :C30H28ClN3O6Couleur et forme :SolidMasse moléculaire :562.013Antitrypanosomal agent 12
<p>Antitrypanosomal agent 12, a C20-phenylthiourea, exhibits trypanocidal and cytotoxic activities, demonstrating antitrypanosomal activity with GI50 values of 0.</p>Formule :C49H77N2NaO10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :909.2Anti-inflammatory agent 40
<p>Anti-inflammatory agent 40 is a promising, orally-active compound with anti-malarial and anti-inflammatory properties.</p>Formule :C30H24Cl2N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :547.43Norselic acid B
CAS :<p>Norselic acid B is a naturally occurring compound that can be isolated from the sponge Crella sp. collected in Antarctica. It demonstrates activity against Leishmania parasites.</p>Formule :C29H44O4Couleur et forme :SolidMasse moléculaire :456.657Antimalarial agent 47
<p>Antimalarial agent 47 (compound F14) is a chemical compound effective against Plasmodium falciparum, specifically targeting the W2 strain with an IC50 value of 235 nM.</p>Formule :C16H14ClF2NOCouleur et forme :SolidMasse moléculaire :309.74LASSBio-1985
<p>LASSBio-1985 is an inhibitor of NHLd (nucleoside hydrolase of Leishmania donovani), with a Ki of 79 μM and an IC50 of 84.6 μM. It exhibits selective toxicity against Leishmania parasites without affecting mammals, showing potential for research in infectious disease treatment.</p>Formule :C18H22N2O7Couleur et forme :SolidMasse moléculaire :378.38Antileishmanial agent-24
<p>Antileishmanial agent-24 (compound 33) exhibits antileishmanial activity, demonstrating an inhibitory concentration 50 (IC50) value of 5.39 μM against</p>Formule :C34H29Cl4N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :653.42AAP4
<p>AAP4 is a potent inhibitor of OfChi-h and OfHex1, exhibiting Ki values of 29.3 nM and 4.9 μM, respectively. It also demonstrates insecticidal activity against the lepidopteran pest Ostrinia furnacalis.</p>Formule :C21H23BrClN7Couleur et forme :SolidMasse moléculaire :488.811Antiproliferative agent-56
<p>Antiproliferative agent-56 (Compound 31) is an antimalarial agent that inhibits the Pf3D7 strain of the malaria parasite Plasmodium falciparum with an IC50 of >12.5 (48h) and 0.03 μM (98h), displaying slow-acting characteristics.</p>Couleur et forme :Odour SolidNitroxynil
CAS :<p>Nitroxynil is an anthelmintic for adult/immature parasites, mainly used in Fasciola hepatica studies.</p>Formule :C7H3IN2O3Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :290.01Antileishmanial agent-25
<p>Antileishmanial agent-25 (compound 24) exhibits selective activity against intracellular amastigotes, demonstrating an inhibitory concentration (IC50) of 6.63</p>Degré de pureté :98%Couleur et forme :Odour SolidAntimalarial agent 43
<p>Antimalarial agent 43 (compound 16c) is an antimalarial compound that exhibits an IC50 value of 0.0151 μM against the 3D7 strain.</p>Couleur et forme :Odour SolidDoxycycline monohydrate
CAS :<p>Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)</p>Formule :C22H26N2O9Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :462.4Urethane
CAS :<p>Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.</p>Formule :C3H7NO2Degré de pureté :99.01%Couleur et forme :SoildMasse moléculaire :89.09Antimalarial agent 28
<p>Antimalarial agent 28 (Compound 2i) acts as an antiplasmodial agent, exhibiting inhibition of P.</p>Formule :C27H25ClFN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.96Amprolium
CAS :<p>Amprolium is a veterinary coccidiostat that interferes with THIAMINE metabolism.</p>Formule :C14H19N4·ClDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :278.79Schizophyllan
CAS :<p>Schizophyllan, a member of the β-glucan family, is an extracellular polysaccharide known for its antitumor, antibacterial, and antiparasitic activities.</p>Couleur et forme :SolidIle-AMS TFA
<p>Ile-AMS TFA exhibits activity against P. falciparum, with an ABSIC50 value of 1.19 nM.</p>Formule :C18H27F3N8O8SCouleur et forme :SolidMasse moléculaire :572.52Mepartricin
CAS :<p>Mepartricin, a polyene macrolide, exhibits both antifungal and antiprotozoal activities and is extensively utilized in studies related to benign prostatic hyperplasia.</p>Couleur et forme :SolidGypsogenic acid
CAS :<p>Gypsogenic acid, a triterpenic acid isolated from Miconia stenostachya, exhibits antibacterial and antitrypanosomal activities. This compound demonstrates minimum inhibitory concentrations (MICs) ranging from 50-200 μg/mL against oral bacterial pathogens including Enterococcus faecalis, Streptococcus salivarius, Streptococcus sanguinis, Streptococcus spp., and Streptococcus sobrinus. Additionally, gypsogenic acid can induce the lysis of Trypanosoma cruzi in isolated mouse blood, with an IC50 value of 56.6 μM.</p>Formule :C30H46O5Couleur et forme :SolidMasse moléculaire :486.684-(2-Aminoethyl)amino-7-chloroquinoline
CAS :<p>4-(2-Aminoethyl)amino-7-chloroquinoline (N1-(7-Chloroquinolin-4-yl)ethane-1,2-diamine) has potential anthelmintic and antitumor activity for the study of</p>Formule :C11H12ClN3Degré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :221.69Febrifugine dihydrochloride
CAS :<p>Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatory</p>Formule :C16H21Cl2N3O3Degré de pureté :98.27% - 99.85%Couleur et forme :SolidMasse moléculaire :374.26TSO-13
<p>TSO-13 is an inhibitor of the major cysteine protease Cruzipain found in Trypanosoma cruzi, with an IC50 of 2.2 μM. In Vero cells, TSO-13 also suppresses T. cruzi, exhibiting an IC50 of 1.9 μM.</p>Formule :C32H36N4O4S2Couleur et forme :SolidMasse moléculaire :604.78Azlocillin sodium salt
CAS :<p>Azlocillin sodium, an acylampicillin, is a broad-spectrum antibiotics</p>Formule :C20H22N5NaO6SDegré de pureté :97.63% - 98.302%Couleur et forme :SolidMasse moléculaire :483.47Cysteine protease inhibitor-3
<p>Cysteine protease inhibitor-3 (Compound 15), a cysteine protease inhibitor, exhibits anti-plasmodial activity, effectively inhibiting Pf3D7 (IC50 = 0.74 μM),</p>Formule :C26H22ClF2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :465.92DCN-83
<p>DCN-83, a potent anti-leishmanial compound, exhibits its highest efficacy against the amastigote form, achieving an IC50 value of 0.71 μM.</p>Formule :C20H18BrN3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.35Sulfadiazine
CAS :<p>Sulfadiazine, a short-acting sulfonamide, blocks bacterial folic acid synthesis; used with pyrimethamine to treat toxoplasmosis in AIDS, newborns.</p>Formule :C10H10N4O2SDegré de pureté :99.32%Couleur et forme :White To Slightly Yellow Crystalline PowderMasse moléculaire :250.28Sarolaner
CAS :<p>Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).</p>Formule :C23H18Cl2F4N2O5SDegré de pureté :99.54% - 99.65%Couleur et forme :SolidMasse moléculaire :581.36Se2h
<p>Se2h is a cruzain inhibitor exhibiting potent activity against intracellular amastigotes of Trypanosoma cruzi (EC50< 1 μM, SI> 10), with an inhibitory effect on cruzain of IC50< 100 nM (SI> 5.55). Compared to Benznidazole and cruzain inhibitor K777, Se2h shows superior selectivity and inhibition while its selenazole structure reduces selenium-related toxicity. Se2h demonstrates antiparasitic activity and holds promise for Chagas disease research.</p>Formule :C12H13ClN4O2SeCouleur et forme :SolidMasse moléculaire :359.67PfSUB1-IN-1
<p>PfSUB1-IN-1 (compound 4c) is an inhibitor of Plasmodium falciparum subtilisin-like serine protease 1 (PfSUB1), exhibiting potent activity with an IC50 value of 15 nM. PfSUB1 is a key target in antimalarial research. PfSUB1-IN-1 demonstrates a 13-fold greater inhibitory effect on the growth of transgenic Plasmodium falciparum strains (expressing lower levels of PfSUB1 compared to the wild-type) than on wild-type parasite strains.</p>Couleur et forme :Odour Solid
