Antiparasitaires
Les antiparasitaires sont des composés conçus pour traiter et prévenir les infections parasitaires en inhibant la croissance et la survie des parasites. Cette catégorie comprend une gamme d'agents antiparasitaires destinés exclusivement à un usage en laboratoire et non à la consommation humaine. Ces produits sont essentiels à des fins de recherche, permettant aux scientifiques d'étudier les cycles de vie des parasites, les mécanismes d'action et le développement de la résistance. L'utilisation d'antiparasitaires en laboratoire aide à la découverte et à l'optimisation de nouveaux traitements pour les maladies parasitaires, contribuant aux avancées en parasitologie médicale et vétérinaire. Les chercheurs comptent sur ces produits pour améliorer leur compréhension des infections parasitaires et développer des thérapies plus efficaces.
704 produits trouvés pour "Antiparasitaires"
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CpCDPK1/TgCDPK1-IN-2
CAS :<p>CpCDPK1/TgCDPK1-IN-2 is a dual inhibitor of CpCDPK1 and TgCDPK1 with IC50 values of 12 and 5 nM for CpCDPK1 and TgCDPK1, respectively.CpCDPK1/TgCDPK1-IN-2 can</p>Formule :C20H21N5ODegré de pureté :99.12%Couleur et forme :SoildMasse moléculaire :347.41PfSUB1-IN-1
<p>PfSUB1-IN-1 (compound 4c) is an inhibitor of Plasmodium falciparum subtilisin-like serine protease 1 (PfSUB1), exhibiting potent activity with an IC50 value of 15 nM. PfSUB1 is a key target in antimalarial research. PfSUB1-IN-1 demonstrates a 13-fold greater inhibitory effect on the growth of transgenic Plasmodium falciparum strains (expressing lower levels of PfSUB1 compared to the wild-type) than on wild-type parasite strains.</p>Couleur et forme :Odour SolidAntileishmanial agent-30
<p>Compound 17k, also known as Antileishmanial agent-30, effectively inhibits Leishmania with an IC50 of 0.2 μM for L. donovani. It exhibits a CC50 of >100 μM and an SI of >500, indicating significant selectivity and potency.</p>Formule :C23H21N5O2Couleur et forme :SolidMasse moléculaire :399.453-Deoxyaphidicolin
CAS :<p>3-Deoxyaphidicolin is a phytotoxin that inhibits root growth in lettuce seedlings. Additionally, 3-Deoxyaphidicolin exhibits inhibitory activity against the protozoan parasites Leishmania major and Leishmania braziliensis.</p>Formule :C20H34O3Couleur et forme :SolidMasse moléculaire :322.48Amitraz
CAS :<p>Amitraz (NSC 324552): white monoclinic crystals, mp 86-87°C, water-insoluble, used as acaricide and in canine demodectic mange.</p>Formule :C19H23N3Degré de pureté :99.88%Couleur et forme :White/Pale Yellow Crystalline SolidMasse moléculaire :293.41Dodecamethylpentasiloxane
CAS :<p>Dodecamethylpentasiloxane can be used as a bed bug insecticide. Dodecamethylpentasiloxane is a component of siloxane and can be used as silicone oil.</p>Formule :C12H36O4Si5Degré de pureté :97.43%Couleur et forme :SolidMasse moléculaire :384.84LL-37 FK-13 TFA
<p>LL-37 FK-13 TFA, the TFA salt form of LL-37 FK-13, is an antimicrobial agent that inhibits Trichomonas vaginalis. It exhibits minimal hemolytic effects on human red blood cells and shows slight cytotoxicity towards human fibroblasts.</p>Couleur et forme :Odour SolidMMV1634566
<p>MMV1634566 is an effective antimalarial agent that can inhibit Plasmodium falciparum and exhibits cytotoxicity.</p>Couleur et forme :Odour SolidAntimalarial agent 42
<p>Compound 42 (Compound 2), an antimalarial agent, effectively inhibits Plasmodium falciparum during the asexual blood stages (IC 50 <0.5μM) and gametocytes (IC 50 is 0.14 μM).</p>Formule :C24H42N2Couleur et forme :SolidMasse moléculaire :358.6AChE-IN-66
<p>Nematicidal Agent 1 is an effective nematicide that binds to the pocket of acetylcholinesterase (AChE).</p>Couleur et forme :Odour SolidBitoscanate
CAS :<p>Bitoscanate (PDITC) is used in the treatment of hookworms.</p>Formule :C8H4N2S2Degré de pureté :98.32%Couleur et forme :Colorless Needles Bitoscanate Is An Odorless Colorless Crystals Melting Point 132°CMasse moléculaire :192.26SpdSyn binder-1
CAS :<p>SpdSyn binder-1 weakly inhibits malaria by binding to Plasmodium falciparum's spermidine synthase. Used for research.</p>Formule :C21H22N4ODegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :346.43Se2h
<p>Se2h is a cruzain inhibitor exhibiting potent activity against intracellular amastigotes of Trypanosoma cruzi (EC50< 1 μM, SI> 10), with an inhibitory effect on cruzain of IC50< 100 nM (SI> 5.55). Compared to Benznidazole and cruzain inhibitor K777, Se2h shows superior selectivity and inhibition while its selenazole structure reduces selenium-related toxicity. Se2h demonstrates antiparasitic activity and holds promise for Chagas disease research.</p>Formule :C12H13ClN4O2SeCouleur et forme :SolidMasse moléculaire :359.67JC-229
CAS :<p>JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).</p>Formule :C20H14Cl4N2O3SDegré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :504.21Insecticidal agent 24
<p>Insecticidal agent 24 is an orally active pyridinyl spiroindoline lead compound. It demonstrates antimalarial activity with Pf NF54IC50 of 0.08 μM. Insecticidal agent 24 also inhibits hERG activity with an IC50 of 6.5 μM. In a humanized immunodeficient NSG mouse model of malaria infection, it effectively reduces parasitemia.</p>Formule :C26H29N3O2Couleur et forme :SolidMasse moléculaire :415.22598pCDPK1/TgCDPK1-IN-3
CAS :<p>CpCDPK1/TgCDPK1-IN-3 inhibits Cp/TgCDPK1; IC50: 0.003/0.0036 µM. It's used to research Toxoplasma, Cryptosporidium diseases.</p>Formule :C17H18N6Degré de pureté :99.63%Couleur et forme :SoildMasse moléculaire :306.36ML251
CAS :<p>ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.</p>Formule :C17H13Cl2N3O4SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :426.271,2-Dimethyl-1H-benzo[d]imidazole
CAS :<p>1,2-Dimethyl-1H-benzo[d]imidazole has antibacterial activity against Entamoeba histolytica and Giardia lamblia,</p>Formule :C9H10N2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :146.19Antimalarial agent 13
CAS :<p>Antimalarial agent 13 (N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine) is a potent antimalarial agent.</p>Formule :C19H15ClN4ODegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :350.8N-Methyl-1,3-benzoxazol-2-amine
CAS :<p>N-Methyl-1,3-benzoxazol-2-amine, with CAS No. 19776-98-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. N-Methyl-1,3-benzoxazol-2-amine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C8H8N2OCouleur et forme :SoildMasse moléculaire :148.1616Eflornithine
CAS :<p>Eflornithine blocks ornithine decarboxylase, treating African trypanosomiasis and female facial hair.</p>Formule :C6H12F2N2O2Degré de pureté :99.44% - 99.84%Couleur et forme :SolidMasse moléculaire :182.17Antileishmanial agent-33
<p>Antileishmanial agent-33 (4e) is a hybrid compound of grandisin and machilin G, demonstrating moderate activity against promastigotes with an IC50 of 38.1 μM. In studies of cutaneous leishmaniasis (CL), Antileishmanial agent-33 (4e) has shown potential as an antileishmanial agent.</p>Couleur et forme :Odour SolidACT-451840
CAS :<p>ACT-451840 eliminates both sensitive and resistant strains of Plasmodium falciparum and has the advantages of oral, potency, low toxicity, rapid.</p>Formule :C47H54N6O3Degré de pureté :96.07%Couleur et forme :SolidMasse moléculaire :750.97Biotin-PEG3-Mal
CAS :<p>Biotin-PEG3-Mal (Biotin-PEG3-NH-Mal) is a biotin-labeled PROTAC linker belonging to the PEG class that can be used to synthesize PROTAC molecules.</p>Formule :C25H39N5O8SDegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :569.67Proteasome-IN-6
<p>Proteasome-IN-6 (Compound J-80) inhibits the β5 catalytic subunit of the Trypanosoma brucei 20S proteasome, effectively blocking T. b. brucei, T. b. gambiense, and T. b. rhodesiense with EC50 values of 157 nM, 220 nM, and 156 nM, respectively. Additionally, Proteasome-IN-6 has demonstrated antitrypanosomal activity in a mouse model.</p>Formule :C35H45F3N4O6Couleur et forme :SolidMasse moléculaire :674.75Pyronaridine tetraphosphate
CAS :<p>Pyronaridine tetraphosphate is a DNA topoisomerase 2 inhibitor with antimalarial and antitumor activity for the treatment of P. falciparum infection.</p>Formule :C29H44ClN5O18P4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :910.03Nanaomycin A
CAS :<p>Nanaomycin A, a quinone antibiotic, reactivates cancer suppressor genes and inhibits DNMT3B (IC50=500nM).</p>Formule :C16H14O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.28WJM280
<p>WJM280 is an orally active antimalarial compound with an EC50 of 0.04 μM against the parasite P. falciparum 3D7.</p>Formule :C22H25F3N2OCouleur et forme :SolidMasse moléculaire :390.44Antimalarial agent 45
<p>Antimalarial agent 45 (compound 8I) is an antimalarial with activity against Plasmodium parasites, exhibiting an IC50 of 0.21 μM. It is used in the study of malaria.</p>Formule :C33H34N4O3Couleur et forme :SolidMasse moléculaire :534.65Mepartricin
CAS :<p>Mepartricin, a polyene macrolide, exhibits both antifungal and antiprotozoal activities and is extensively utilized in studies related to benign prostatic hyperplasia.</p>Couleur et forme :SolidSchizophyllan
CAS :<p>Schizophyllan, a member of the β-glucan family, is an extracellular polysaccharide known for its antitumor, antibacterial, and antiparasitic activities.</p>Couleur et forme :SolidIle-AMS TFA
<p>Ile-AMS TFA exhibits activity against P. falciparum, with an ABSIC50 value of 1.19 nM.</p>Formule :C18H27F3N8O8SCouleur et forme :SolidMasse moléculaire :572.52Cinchonidine
CAS :<p>Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.</p>Formule :C19H22N2ODegré de pureté :94.96% - 99.87%Couleur et forme :White PowderMasse moléculaire :294.39Gypsogenic acid
CAS :<p>Gypsogenic acid, a triterpenic acid isolated from Miconia stenostachya, exhibits antibacterial and antitrypanosomal activities. This compound demonstrates minimum inhibitory concentrations (MICs) ranging from 50-200 μg/mL against oral bacterial pathogens including Enterococcus faecalis, Streptococcus salivarius, Streptococcus sanguinis, Streptococcus spp., and Streptococcus sobrinus. Additionally, gypsogenic acid can induce the lysis of Trypanosoma cruzi in isolated mouse blood, with an IC50 value of 56.6 μM.</p>Formule :C30H46O5Couleur et forme :SolidMasse moléculaire :486.68Cletoquine
CAS :<p>Cletoquine, Hydroxychloroquine's active metabolite, fights CHIKV, has antimalarial properties, and may treat autoimmune diseases.</p>Formule :C16H22ClN3ODegré de pureté :99.95% - 99.98%Couleur et forme :SolidMasse moléculaire :307.82Antitrypanosomal agent 15
<p>Antitrypanosomal Agent 15 (Compound 26) is an orally active, brain-penetrant, selective inhibitor of the Trypanosoma cruzi proteasome, exhibiting a pIC50 of 7.4</p>Formule :C21H19FN4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :410.4Human α-defensin 5
<p>Human α-defensin 5 is an antiviral peptide that inhibits the infection of non-enveloped viruses such as AdV, HPV, and polyomaviruses, with an IC50 range of 0.6-</p>Formule :C144H238N50O45S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3582.13Urethane
CAS :<p>Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.</p>Formule :C3H7NO2Degré de pureté :99.01%Couleur et forme :SoildMasse moléculaire :89.09Antiparasitic agent-25
<p>Antiparasitic agent-25 (Compounds 11) is an orally active antiparasitic compound. It inhibits the invasion and replication capabilities of parasites and has an irreversible effect on Toxoplasma gondii. The agent significantly reduces the replication rate of Toxoplasma gondii, with an IC50 value of 6.33 μM, and exhibits low cytotoxicity, having a CC50 value of 285 μM.</p>Couleur et forme :Odour SolidFebrifugine dihydrochloride
CAS :<p>Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatory</p>Formule :C16H21Cl2N3O3Degré de pureté :98.27% - 99.85%Couleur et forme :SolidMasse moléculaire :374.264-Propylbenzene-1,2-diol
CAS :<p>4-Propylbenzene-1,2-diol exhibits antimalarial activity and can inhibit Plasmodium falciparum,</p>Formule :C9H12O2Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :152.19Modoflaner
CAS :<p>Modoflaner is an antiparasitic (veterinary use).</p>Formule :C23H10F12IN3O2Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :715.23Antimalarial agent 49
<p>Antimalarial agent 49 is an oral compound with antimalarial properties. It inhibits the growth of Pf3D7 and PfK1 strains, with IC50 values of 0.84 μM and 0.4 μM, respectively. Additionally, it demonstrates the ability to suppress the liver stage development of P. berghei and can be utilized in malaria infection research.</p>Couleur et forme :Odour SolidAntiparasitic agent-24
<p>Antiparasitic agent-24 (Compound 14a) is an antiparasitic compound with EC50 values of 0.005 μM for L. maj, 0.069 μM for L. don, 0.82 μM for T. brucei, and 4.1 μM for T. cruzi.</p>Formule :C23H22ClN7O2SCouleur et forme :SolidMasse moléculaire :495.98CCOE-5
<p>CCOE-5 is a chalcone derivative with antimalarial activity, exhibiting an IC50 of 1.4 μg/mL against P. falciparum (3D7) and an IC50 of less than 5 μg/mL against P. falciparum (INDO). CCOE-5 shows potential for research in the anti-infective domain.</p>Formule :C34H31NO6Couleur et forme :SolidMasse moléculaire :549.61Sarolaner
CAS :<p>Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).</p>Formule :C23H18Cl2F4N2O5SDegré de pureté :99.54% - 99.65%Couleur et forme :SolidMasse moléculaire :581.36Dixanthogen
CAS :<p>Dixanthogen (Auligen) is an ectoparasiticide. Dixanthogen is a thiocarbonyl compound.</p>Formule :C6H10O2S4Degré de pureté :95% - 98%Couleur et forme :SolidMasse moléculaire :242.4Azlocillin sodium salt
CAS :<p>Azlocillin sodium, an acylampicillin, is a broad-spectrum antibiotics</p>Formule :C20H22N5NaO6SDegré de pureté :97.63% - 98.302%Couleur et forme :SolidMasse moléculaire :483.47Arprinocid
CAS :Formule :C12H9ClFN5Degré de pureté :>95.0%(HPLC)Couleur et forme :White to Yellow to Orange powder to crystalMasse moléculaire :277.69Albendazole Sulfoxide
CAS :Formule :C12H15N3O3SDegré de pureté :>98.0%(N)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :281.33
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