Stéroïdes

Applications 4-Androsten-17alpha-ol-3-one-2,2,4,6,6-d5 (CAS# 165195-35-7) is a useful isotopically labeled research compound.

Applications 1,4-Pregnadien-6alpha-methyl-11beta,17alpha,21-triol-3,20-dione-21,21-d2 is a useful isotopically labeled compound of 6α-Methyl Prednisolone (M325934)

Applications Cholesteryl n-butyrate (cas# 521-13-1) is a useful research chemical.

Applications 5-Androstenediol is a steroid androgen metabolite of Testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.
References Miller, M., et al.: Steroids., 78, 15 (2013); Baker, M.E., et al.: Steroids., 77, 1192 (2012); Ronis, M.J.J. et al.: Comp. Biochem. Physiol.-C: Pharmacol. Toxicol. Endocrinol., 121C, 221 (1998);

Applications Progesterone (P755900) impurity.
References Liang, T., et al.: Biol. Chem., 256, 7998 (1981), Bratoeff, E., et al.: J. Steroid Biochem. Mol. Biol., 111, 275 (2008),

Applications 6β-Hydroxy Betamethasone can be used as analyte in analytical study for detecting betamethasone metabolites in human urine using liquid chromatography coupled to tandem mass spectrometry.
References Matabosch, X., et al.: Drug Testing and Analysis, 7, 663-672 (2015)

Applications 7,7-Azo-3-α,12-α-dihydroxycholanic Acid (cas# 86992-52-1) is a compound useful in organic synthesis.

Impurity Beclomethasone Dipropionate EP Impurity I
Applications (16β)-16-Methyl-17,21-bis(1-oxopropoxy)pregna-1,4,9(11)-triene-3,20-dione (Beclomethasone Dipropionate EP Impurity I) is an impurity of Beclomethasone (B131000), a glucocorticoid. Used in chronic asthma and allergic rhinitis. Antiallergic, antiasthmatic (inhalant). Anti-inflammatory (topical).
References Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982), Rao, M., et al.: J. Asthma, 19, 21 (1982), Small, P., et al.: Ann. Allergy, 49, 127 (1982), Brogden, R.N., et al.: Drugs, 28, 99 (1984),

Applications 17beta-Dihydroequilin-2,4,16,16,17-d5 is a useful isotopically labeled compound of 17β-Dihydro Equilin (D449130)

Impurity Beclometasone Dipropionate EP Impurity C
Applications An impurity of Beclomethasone Dipropionate (B131030).

Applications Prostanozol (P838700) derivative.

Applications Δ6-Gestodene, is an impurity of Gestodene (G368250), an orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive.
References Duesterberg, B., et al.: Contraception, 24, 673 (1981); Duesterberg, B., et al.: Seroids, 43, 43 (1984); Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985);

Applications 4-Methoxy-17beta-estradiol-1,2,16,16,17-d5 is a useful isotopically labeled compound of 4-Methoxy 17β-Estradiol (M262630)

Applications Sitostanol-d7 is a compound useful in organic synthesis.

Applications The minor metabolite of Deflazacort.
References Bernareggi, A., et al.: J. Pharma. Biomed. Anal., 5, 177-81 (1987), Assandri, A., et al.: Xenobiotica, 13(3), 185 (1983), Martinelli, E., et al.: Drug Metab. Dispos., 7, 335 (1979),

Impurity Fulvestrant Impurity E;
Applications Fulvestrant (F862500) impurity E.

Applications Tauro 6-Ethlchenodeoxycholic Acid Sodium Salt can be otained from 6-Ethylchenodeoxycholic Acid (E899810) which is a derivative of the bile acid Chenodeoxycholic Acid (C291900). 6-Ethylchenodeoxycholic Acid (E899810) is a potent activator of the farnesoid X nuclear receptor which reduces liver fat and fibrosis in animal models of fatty liver disease.
References Neuschwander-Tetri, B.A., et al.: Lancet., 385, 956 (2015)

Applications 5alpha-Pregnan-3,20-dione-2,2,4,4,17alpha,21,21,21-d8 is a useful isotopically labeled compound of (5α)-Pregnane-3,20-dione (P705150)

Applications Tauro-d4-cholic Acid Sodium Salt is a useful isotopically labeled compound of Sodium Taurocholate (S080848)

Applications Epoxy Metradiene is an impurity from synthesis of Fluorometholone (F593145),a glucocorticoid; anti-inflammatory.
References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982); Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984);

Applications An impurity of Norethindrone Acetate (N675990).

Applications Glucocorticoid.

Applications 4-Pregnen-11beta,17alpha-diol-3,20-dione-2,2,4,6,6,21,21,21-d8 is a useful isotopically labeled compound of 21-Deoxy Cortisol (D232605)

Applications Testosterone Palmitate-d31 is the labeled analogue of Testosterone Palmitate (T155140) which is found in male serum.
References Addo, S.B., et. al.: Steroid, 54, 257 (1989)

Applications 4-Pregnen-17alpha,21-diol-3,20-dione-21,21-d2 (CAS# 1271728-08-5) is a useful isotopically labeled research compound.

Applications Used in the preparation of Epostane (E588850).

Applications 4-Methoxyestrone-1,2,16,16-d4 is a useful isotopically labeled compound of 4-Methoxy Estrone (M226135)

Applications 1,4-Androstadien-17alpha-methyl-17beta-ol-3-one-2,4,6alpha-d3 is a useful isotopically labeled compound of Methandrostenolone (M226000)

Impurity Levonorgestrel EP Impurity D
Applications 13-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (Levonorgestrel EP Impurity D) is an impurity of Levonorgestrel.
References McGinty, D., et al.: Endocrinology, 24, 829 (1939), Belanger, A., et al.: Steroids, 37, 361 (1981), Nieman, L., et al.: J. Clin. Endocrinol. Metab., 61, 536 (1985), Klebe, G., et al.: J. Med. Chem., 37, 4130 (1994),

Applications 3β-Dihydroxy-19-norandrost-5(10)-ene is an intermediate in the synthesis of 3β,17β-Dihydroxy-19-norandrost-5(10)-ene (D453800), which is a metabolite of Androstenedione. A novel 19-norsteroid, from androstenedione and 19-hydroxyandrostenedione by cultured porcine granulosa cells is reported for the first time.
References Haarbo, J., et al.: Clin. Physiol., 11, 331 (1991), Krebs-Smith, S., et al.: Eur. J. Clin. Nutr., 54, 281(2000), Rasmussen, B., et al.: J. Clin. Endocrinol. Metab., 85, 55 (2000),

Applications 20β-Dihydro Pregnenolone is a metabolite of Pregnenolone (P712200).
References Purdy, R., et al.: J. Med. Chem., 33, 1572 (1990), Bixo, M., et al.: Brain Res., 764, 173 (1997), Huang, X., et al.: J. Biol. Chem., 275, 29452 (2000),

Applications 17α-Boldenone (B675105) derivative.

Applications Steroidal fused pyrazoles useful as bile acid transporters.
References Bhat, L. et al.; Bioorgan. Med. Chem. 15, 85 (2005)

Applications 21-Acyloxycorticosteroid derivative. Antiinflammatory.
References Ko, D. et al.; Steroids 67, 211 (2002)