Flavonoïdes

<p>Kaempferol 3-O-b-D-glucuronide is a bioactive flavonoid glucuronide, which is a naturally occurring compound found in various plants, fruits, and vegetables. It is formed through the glucuronidation of the parent compound, kaempferol, a process which enhances its solubility and bioavailability. This compound exhibits significant antioxidant activity through its ability to scavenge free radicals and reduce oxidative stress within biological systems.</p>

<p>Scutellarin is a bioactive flavonoid compound, which is derived primarily from the plant Scutellaria baicalensis and other species within the Scutellaria genus. As a naturally occurring phytochemical, Scutellarin exerts its effects through multiple biological pathways, including antioxidant, anti-inflammatory, and anti-apoptotic activities.</p>

<p>Cupressuflavone is a naturally occurring biflavonoid compound, which is an organic molecule composed of two flavonoid units linked together. Its source is predominantly from the Cupressaceae family, specifically from plants such as cypress trees. This compound is characterized by its potent antioxidant properties, which allow it to scavenge free radicals and reduce oxidative stress in biological systems.</p>

<p>Salvigenin is a flavone compound, which is found in various species of the Salvia plant. It is a naturally occurring phytochemical characterized by its potential to modulate biological pathways. Salvigenin primarily acts by interacting with biochemical pathways, exhibiting antioxidant and anti-inflammatory activities. These activities are thought to result from its ability to modulate enzyme activity, influence signaling pathways, and scavenge free radicals.</p>

<p>3'-Hydroxyflavanone is a naturally occurring flavonoid compound, which is derived from various plant sources, including citrus fruits and some leguminous plants. Its chemical structure contains a flavanone backbone with a hydroxyl group at the 3' position, contributing to its unique properties and biological activity.</p>

<p>Swertisin is a naturally occurring flavonoid, which is extracted primarily from medicinal plants like Swertia and Enicostemma species. This compound is a C-glycosyl flavone, found in various herbs traditionally used in different cultural medicinal practices. The mode of action of Swertisin involves its interaction with cellular pathways, leading to anti-inflammatory, antioxidant, and potential anti-diabetic effects. These bioactivities are primarily mediated through modulation of enzyme activity and gene expression related to oxidative stress and inflammation.</p>

<p>7-Benzyloxy-2',4'-dimethoxyisoflavone is a synthetic isoflavone, which is a type of phenolic compound. Isoflavones are derived from plants, commonly found in soybeans and other legumes, and are often synthesized in laboratories for research and pharmaceutical purposes. These compounds are known for their structural similarity to estrogens and their ability to act as phytoestrogens.</p>

<p>3-Hydroxy-5,7-dimethoxyflavone is a naturally occurring flavonoid, which is primarily derived from various plant sources. This compound belongs to a class of polyphenolic substances known as flavonoids, which are commonly found in fruits, vegetables, and certain herbs. Flavonoids such as 3-Hydroxy-5,7-dimethoxyflavone are known for their diverse biological activities due to their unique structural configurations and ability to interact with various biological targets.</p>

Icariside II is a natural product derived from Epimedium brevicornu Maxim (E. brevicornu) that exhibits various beneficial properties as a small molecule drug candidate. It has been shown to induce apoptosis in K562 cells, making it a potential treatment for leukemia. Icariside also regulates MAPK signaling, which plays a crucial role in cell growth and differentiation. Moreover, it has been found to promote osteogenesis, making it a promising candidate for bone health. With its unique properties and potential therapeutic applications, Icariside II is an interesting candidate for small molecule studies and drug development research.This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

<p>2'-Methoxyflavonol is a methoxyflavonoid, which is a type of polyphenolic compound. It is derived from natural sources, primarily plants where flavonoids are commonly found. These compounds are known for their wide range of biological activities.</p>

<p>Phaseollinisoflavan is a naturally occurring isoflavone compound, which is derived from the legume plant, Phaseolus vulgaris, commonly known as the common bean. Its mode of action primarily involves the inhibition of enzymatic activity, particularly affecting pathways related to oxidative stress and various metabolic processes. This isoflavone exerts its effects by modulating signal transduction pathways, which are critical in cellular response mechanisms.</p>

<p>(+)-trans-Taxifolin is a flavonoid compound, which is a type of plant secondary metabolite. It is naturally found in various plant sources, including the bark of Douglas fir (Pseudotsuga menziesii) and Siberian larch (Larix sibirica), as well as in milk thistle. The primary mode of action of this compound is its antioxidant activity, which involves scavenging free radicals and reducing oxidative stress within cells. This activity is facilitated by its ability to donate hydrogen atoms or electrons to neutralize reactive oxygen species, thus preventing cellular damage.</p>

Oroxylin A is a natural flavonoid compound, which is derived from the root of Scutellaria baicalensis, commonly known as Baikal skullcap. It is primarily recognized for its bioactive properties, attributed to its modulation of various biochemical pathways. Oroxylin A acts by inhibiting the activity of certain enzymes, such as cyclooxygenase, and influencing signaling pathways like NF-kB, which are integral to inflammatory responses. It also exhibits potent neuroprotective effects by interacting with GABA_A receptors, thereby influencing neurotransmission.

<p>3',4',7-Trihydroxyflavone is a naturally occurring flavonoid compound, which is derived from a variety of plant sources. It is a type of secondary metabolite commonly found in fruits, vegetables, and certain herbs. This compound exerts its effects primarily through its antioxidant properties, which involve scavenging free radicals and modulating oxidative stress pathways in biological systems.</p>

<p>3',4',5',5,7-Pentamethoxyflavone is a synthetic flavonoid compound, which is derived from the structural modification of naturally occurring flavonoids found in various plants. The compound is specifically produced for research and development purposes, exploring its biological and pharmacological potential. The mode of action involves interaction with various cellular pathways, including modulation of enzyme activity, influence on cell signaling pathways, and potential antioxidant properties due to its polyphenolic structure.</p>

<p>Quercetin-7,4'-diglucoside is a flavonoid glycoside, which is a bioactive compound derived from various plants, particularly in fruits, vegetables, and certain leaves. It functions through its ability to modulate cellular pathways related to oxidative stress and inflammation, acting as a potent antioxidant and anti-inflammatory agent. These modes of action are primarily attributed to its capacity to scavenge free radicals and attenuate the expression of pro-inflammatory cytokines by interfering with signaling pathways, such as NF-κB and MAPK.</p>

<p>3'-Benzyloxy-5,7-dihydroxy-3,4'-dimethoxyflavone is a synthetic flavone derivative, which is primarily obtained through targeted chemical synthesis in laboratory settings. This compound belongs to a broader class of polyphenolic flavonoids, which are known for their potential bioactive properties.</p>

<p>Neoschaftoside is a naturally occurring bioactive compound, which is an acylated flavonoid C-glycoside. It is primarily sourced from various plant species, including members of the Poaceae and Fabaceae families. The compound functions through its antioxidant and anti-inflammatory properties, interacting with cellular pathways to mitigate oxidative stress and modulate immune responses. These actions make neoschaftoside a compound of interest in pharmacological research, particularly in the study of chronic diseases where inflammation and oxidative damage are key pathological features. Its applications extend to potential therapeutic development in areas such as cardiovascular health, neuroprotection, and metabolic disorders. The ongoing investigation into its modes of action and bioavailability continues to reveal insights into its efficacy and potential as a natural therapeutic agent.</p>

Inhibitor of HSP70 and HSP27 expression

<p>6-Prenylquercetin is a prenylated flavonoid, which is a type of natural compound known for its diverse biological activities. This compound is derived from the prenylation of quercetin, a flavonoid commonly found in fruits and vegetables, particularly in onions, apples, and berries. The addition of a prenyl group to quercetin alters its physicochemical properties, enhancing its bioavailability and specific biological interactions.</p>

Luteone is a natural compound, which is a plant-derived flavonoid isolated from various botanical sources. It exhibits a range of biological activities primarily due to its ability to modulate key cellular mechanisms. Luteone functions through its interaction with multiple molecular targets, demonstrating antioxidant, anti-inflammatory, and anti-cancer properties by influencing signaling pathways and gene expression related to cellular stress responses and apoptosis.

<p>Eupatorin - 98% is a high-purity flavonoid compound, which is extracted primarily from various plant species such as Eupatorium. This compound is renowned for its bioactive properties, engaging in numerous biochemical interactions that contribute to its therapeutic potentials. Eupatorin operates through multiple biochemical pathways as an inhibitor of specific enzymes like cytochrome P450s and as a modulator of cellular signaling pathways. This enables it to exert anti-inflammatory, anticancer, and antioxidant effects, making it a valuable subject of study in pharmaceutical and clinical research.</p>

<p>Dihydroprunetin is a synthetic analog of natural flavonoid compounds, which is derived from chemical modifications of prunetin, originally sourced from various plant species. It functions primarily as an antioxidant by inhibiting oxidative stress pathways and scavenging free radicals. This activity is attributed to modifications that enhance its stability and bioavailability compared to its natural counterparts.</p>

<p>Dehydroequol is a dietary supplement ingredient, which is a metabolite of the soy isoflavone daidzein. It is produced through the biotransformation by certain gut bacteria that convert daidzein into equol compounds, specifically the dehydrogenated form. This compound is noted for its estrogenic activity, acting primarily as a selective estrogen receptor modulator (SERM). Dehydroequol binds to estrogen receptors with a preference for the beta subtype, exerting moderate estrogenic effects.</p>

<p>7-Benzyloxy-2',3',4'-trimethoxyisoflavone is a synthetic isoflavone, which is a type of flavonoid compound often derived from plant secondary metabolites. Its source lies in laboratory synthesis, using specific chemical reactions to obtain the desired isoflavone structure with a benzyloxy group and methoxy groups at specified positions on the molecule.</p>

<p>Natually produced by plants such as liquorice, liquiritin is formed by the linkage between liquiritigenin and a beta-D-glucopyranosyl residue at position 4. Liquiritin clinical relevance has been as an antiviral and anti-inflammatory agent. In 2020, an artificial intelligent approach has indicated that liquiritin might inhibit SARS-CoV-2 by acting similarly to type I interferon.</p>

<p>Texasin 7-O-glucoside is a flavonoid glycoside, which is a plant-derived compound with significant antioxidant properties. This glycoside is sourced primarily from plants, where it naturally occurs as a secondary metabolite. It is composed of the flavonoid backbone, texasetin, conjugated with a glucose molecule at the 7-O position, enhancing its solubility and bioavailability in biological systems.</p>

<p>Eupafolin is a naturally occurring flavonoid compound, specifically a flavone, which is derived from certain medicinal plants, primarily in the genus *Artemisia*. It is a secondary metabolite found in various parts of these plants, including the leaves and stems. As a bioactive substance, eupafolin exerts its effects through several biochemical pathways, most notably by scavenging free radicals and modulating inflammatory responses. Its mode of action involves the inhibition of key enzymes and molecules in the inflammatory cascade, as well as the upregulation of antioxidant defenses.</p>

<p>Hesperetin is a flavonoid compound, which is naturally derived from citrus fruits such as oranges and lemons. As a notable bioactive molecule, its mode of action primarily involves the modulation of oxidative stress and inflammatory pathways. Hesperetin exerts its effects by scavenging free radicals and inhibiting the activation of inflammatory cytokines, making it a compound of significant interest in the biochemical and pharmacological sectors.</p>

3,7,3'-Trihydroxyflavone is a flavonoid derivative, which is a type of polyphenolic compound commonly found in various plants and is derived from natural sources like fruits, vegetables, and herbal plants. It is characterized by its polyphenolic structure, which contributes to its ability to scavenge free radicals and reduce oxidative stress.

<p>Pratensein is an isoflavone compound that is derived primarily from plants such as red clover (Trifolium pratense). This natural product belongs to the class of phytochemicals known for their diverse biological activities. Pratensein is sourced through the extraction and purification processes that involve isolating the bioactive components from plant materials rich in flavonoids.</p>

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7-Hydroxyflavanone is a naturally occurring flavonoid compound, which is predominantly isolated from plants, particularly citrus fruits. Its biochemical significance stems from its ability to exert various physiological effects, likely due to its structural characteristics. As a flavonoid, it possesses a range of hydroxyl groups, which contribute to its antioxidant properties. This compound interacts with biological molecules, influencing cellular pathways and modulating enzyme activities.

<p>Pinocembrin dimethylether is a flavonoid derivative, which is synthesized from natural sources such as honey, propolis, and certain plants. It retains the core flavonoid structure while being modified to enhance its bioavailability and stability. This compound acts primarily as a neuroprotective agent through its antioxidative and anti-inflammatory properties. It interacts with various molecular pathways to mitigate oxidative stress and reduce neuroinflammation, contributing to cellular protection.</p>

<p>5,7,8,4'-Tetramethoxyflavone is a naturally occurring flavone, which is a type of plant-derived polyphenolic compound. It is found in various plants, particularly those belonging to the genus Scutellaria. The compound acts primarily by modulating various cellular signaling pathways, including those involved in inflammation, apoptosis, and oxidative stress. Through its interaction with these pathways, it exhibits potential anti-inflammatory, antioxidant, and anti-cancer properties.</p>

<p>2'-Hydroxy-β-naphthoflavone is a synthetic flavonoid, which is derived from structural modifications of natural flavonoids. It functions as a potent aryl hydrocarbon receptor (AhR) agonist and enzyme inducer. The structure is based on a naphthoflavone framework, allowing it to efficiently interact with cellular proteins related to xenobiotic metabolism.</p>

<p>3-Methoxyflavone is a synthetic flavonoid, which is a type of product known for its biological activities and potential therapeutic applications. It is derived from flavones, naturally occurring compounds found in various plants, known for their role in plant pigmentation and UV protection. The compound's mode of action is primarily through interaction with various biological targets, including modulation of enzyme activity and regulation of signal transduction pathways.</p>

<p>3-Hydroxy-7,8-dimethoxyflavone is a synthetic flavonoid derivative, which is structurally sourced from the broader class of naturally occurring flavonoids found in various plants. It functions primarily as a potent and selective ligand for the TrkB receptor, a receptor for brain-derived neurotrophic factor (BDNF). This interaction mimics the effects of BDNF, promoting neuronal survival, synaptic plasticity, and neurogenesis, thereby facilitating neuroprotective and neurorestorative processes.</p>

Apigenin-7-glucoside is a naturally occurring flavonoid glycoside, which is derived primarily from various plant sources, including parsley, celery, chamomile, and some fruits. This compound is formed when apigenin, a flavonoid, is conjugated with a glucose molecule. The interaction with glucose enhances its solubility and bioavailability in biological systems.

<p>3-Hydroxy-7,2',4'-trimethoxyflavone is a specialized flavone compound, which is a type of polyphenolic molecule commonly found in a variety of plants. This product is naturally derived, often isolated from diverse botanical sources like various species of herbs and flowering plants known for their medicinal properties. The compound exhibits various biological activities through its interactions with cellular pathways, predominantly by modulating enzymatic functions and signaling pathways that influence oxidative stress and inflammation.</p>

3-Hydroxy-7,2',3'-trimethoxyflavone is a naturally occurring flavonoid, which is a type of polyphenolic compound commonly found in plants. These compounds are typically sourced from various plant species where they are known to contribute to pigmentation and offer protective functions.

<p>Alnusin is a phytochemical compound, which is a naturally occurring flavonoid sourced from the bark and leaves of the alder tree (genus Alnus). This compound is structurally categorized as an O-methylated flavonoid, specifically demonstrating unique biological activities.</p>

<p>Biflavonyl pigment; anti-inflammatory; analgesic</p>

<p>Tricetin is a naturally occurring flavonoid compound, which is primarily sourced from various plant species. Its molecular structure comprises multiple hydroxyl groups, contributing to its biological activity. Tricetin functions by modulating several biochemical pathways; it exhibits antioxidant properties through scavenging of reactive oxygen species and chelation of metal ions. Additionally, Tricetin possesses anti-inflammatory effects, as it can inhibit the synthesis of pro-inflammatory cytokines and downregulate the expression of enzymes involved in inflammation, such as cyclooxygenase and lipoxygenase.</p>

<p>3',4'-Dimethoxy-beta-naphthoflavone is a synthetic chemical compound, which is a selective aryl hydrocarbon receptor (AhR) agonist, derived from flavonoid structures. With its capacity to modulate xenobiotic metabolism, this compound acts as an inducer of cytochrome P450 enzymes, specifically CYP1A1 and CYP1A2, through the activation of the AhR pathway. Upon binding to AhR, 3',4'-Dimethoxy-beta-naphthoflavone translocates to the nucleus, where it influences gene expression involved in xenobiotic metabolism.</p>

4'-Methoxyflavanone is a methoxy-substituted flavanone, which is a specialized class of flavonoids. These compounds are primarily derived from plant sources and are known for their diverse biological activities. The modification of the flavanone structure with a methoxy group can significantly influence its biochemical interactions and properties.

<p>6,4'-Dimethoxyflavone is a naturally occurring flavone, which is a type of polyphenolic compound typically found in various plants. It is derived from natural sources such as certain species of citrus fruits and other flavonoid-rich plants. The compound is characterized by the presence of two methoxy groups attached to its flavone backbone.</p>

<p>Scutellarein-6,4'-dimethyl ether is a flavonoid derivative, which is a type of polyphenolic compound widely found in the plant kingdom. It is primarily sourced from various species within the genus Scutellaria, known for their rich flavonoid content. Scutellarein-6,4'-dimethyl ether demonstrates an affinity for interacting with key biological pathways, including exerting possible antioxidant activities by scavenging free radicals and modulating redox states, as well as potential anti-inflammatory effects through the regulation of inflammatory mediators.</p>

Kaempferol-3-O-rhamnoside is a naturally occurring flavonoid glycoside, which is derived from various plants, particularly those in the families Rosaceae and Brassicaceae. This compound is a significant bioactive component found in herbs, fruits, and vegetables. Its mode of action primarily involves the scavenging of free radicals, inhibition of oxidative stress, and modulation of various signaling pathways related to inflammation and apoptosis.

<p>Mucronulatol is a naturally occurring compound, which is derived from certain plant species known for their rich array of bioactive compounds. As a product of natural origin, mucronulatol is classified as a polyphenolic compound. Its biosynthesis in plants is a part of the complex secondary metabolism, playing roles in defense mechanisms against environmental stressors and pathogens. The mode of action of mucronulatol involves modulation of various biochemical pathways, which may include antioxidant activity, enzyme inhibition, or signaling pathway regulation. This capacity makes mucronulatol a subject of interest in pharmacological and therapeutic research.</p>