Cannabinoïdes
Les cannabinoïdes sont une classe de composés chimiques divers dérivés des acides gras ou des polykétides, qui agissent sur les récepteurs cannabinoïdes des cellules, modifiant ainsi la libération de neurotransmetteurs dans le cerveau. Principalement présents dans les plantes de cannabis, des cannabinoïdes comme le THC et le CBD sont largement étudiés pour leurs effets thérapeutiques, notamment le soulagement de la douleur, leurs propriétés anti-inflammatoires, et leur utilisation potentielle dans les maladies neurodégénératives. Chez CymitQuimica, vous trouverez une grande variété de cannabinoïdes pour la recherche en pharmacologie, neurobiologie, et chimie médicale.
299 produits trouvés pour "Cannabinoïdes"
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GSK494581A
CAS :<p>GSK494581A is a GPR55 agonist and glycine transporter subtype 1 inhibitor.</p>Formule :C27H28F2N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :514.58URB447
CAS :<p>URB447, a peripherally restricted CB1 cannabinoid antagonist with IC50 values of 313 nM for rat CB1 receptor and 41 nM for human CB2 receptor, effectively reduces food intake and body weight gain in mice. It achieves these effects without penetrating the brain or antagonizing central CB1-dependent responses, making it a potential research tool for obesity studies [1].</p>Formule :C25H21ClN2OCouleur et forme :SolidMasse moléculaire :400.9CB-52
CAS :<p>CB-52 acts as a neutral antagonist and ligand for the CB2 cannabinoid receptor [1].</p>Formule :C26H43NO3Couleur et forme :SolidMasse moléculaire :417.62Isopropyl dodec-11-enylfluorophosphonate
CAS :<p>Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist and exhibits</p>Formule :C15H30FO2PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.37O-Arachidonoyl glycidol
CAS :<p>O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].</p>Formule :C23H36O3Couleur et forme :SolidMasse moléculaire :360.53OMDM-5
CAS :<p>OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).</p>Formule :C26H44N2O3Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :432.64AM841
CAS :<p>AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor.</p>Formule :C26H39NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.66CB-25
CAS :<p>CB-25 is a partial agonist ligand of CB1 cannabinoid receptors, augmenting Forskolin-induced cAMP formation in cancer cells, though not affecting hCB1-CHO cells</p>Formule :C25H41NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :403.6CAY10508
CAS :<p>CAY10508 is a potent and selective inverse agonist for the central cannabinoid (CB1) receptor with therapeutic potential for treating obesity and drug dependence, lacking psychotropic effects. It exhibits a Ki value of 243 nM and an EC50 of 195 nM. At a concentration of 10 µM, CAY10508 displaces [3H]-CP-55,940 with 100% efficacy at the CB1 receptor and 35% at the peripheral cannabinoid (CB2) receptor. Its inverse agonist activity at the CB1 receptor was confirmed through a [35S]-GTPγS binding assay.</p>Formule :C21H14Br2N2O2Couleur et forme :SolidMasse moléculaire :486.2O-2050
CAS :<p>O-2050: strong CB1 antagonist (Ki 2.5 nM), CB2 inhibitor (Ki 0.2 nM); reduces mouse food intake, increases activity.</p>Formule :C23H31NO4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :417.56GW405833 hydrochloride
CAS :<p>GW405833 hydrochloride, a potent and selective agonist of the cannabinoid-2 (CB2) receptor (EC 50 = 0.65 nM; maximum inhibition = 44.6%), exhibits significant antihyperalgesic effects in various rodent pain models [1] [2] [3].</p>Formule :C23H25Cl3N2O3Couleur et forme :SolidMasse moléculaire :483.82Tedalinab
CAS :<p>Tedalinab is an effective and selective cannabinoid receptor 2 agonist.</p>Formule :C19H21F2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :345.392-Linoleoyl Glycerol
CAS :<p>2-Arachidonoyl glycerol (2-AG), a natural endocannabinoid ligand for the CB1 receptor, was isolated from porcine brain and characterized. Its congener, 2-linoleoyl glycerol (2-LG), which has a linoleoyl group instead of an arachidonoyl group, also exists alongside 2-AG in vivo. While 2-LG exhibits low intrinsic activity, it enhances the activity of 2-AG and other endocannabinoids through an "entourage" effect, attributed to the inhibition of breakdown and reuptake pathways that typically decrease endocannabinoid levels post-release.</p>Formule :C21H38O4Couleur et forme :SolidMasse moléculaire :354.531CB1 antagonist 1
CAS :<p>CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, and</p>Formule :C26H22Cl2N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.39CB1 inverse agonist 1
CAS :<p>MRL-650 is an oral, selective CB1 agonist; IC50: CB1=7.5 nM, CB2=4100 nM; anorexigenic effects noted.</p>Formule :C25H18Cl3N3O3Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :514.79(R)-Monlunabant
CAS :<p>(R)-Monlunabant ((R)-MRI-1891) serves as a CB1 receptor antagonist utilized in obesity and metabolic disease research [1].</p>Formule :C26H22ClF3N6O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :591Amauromine
CAS :<p>Amauromine is a peripherally selective and potent cannabinoid receptor type 1 (CB1) receptor antagonist, a novel alkaloid with vasodilatory activity.</p>Formule :C32H36N4O2Couleur et forme :SolidMasse moléculaire :508.65CB 65
CAS :<p>CB 65 is a high affinity and selective CB2 receptor agonist with Ki values of 3.3 and > 1000 nM for CB2 and CB1 receptors respectively.</p>Formule :C22H28ClN3O3Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :417.93GSK-554418A
CAS :<p>GSK-554418A, a novel azaindole CB(2) agonists, is used for the treatment of chronic pain. It is efficacious in the acute model and the chronic joint pain model.</p>Formule :C19H19ClN4O2Couleur et forme :SolidMasse moléculaire :370.83Hemopressin(rat) TFA
CAS :<p>Hemopressin(rat) TFA, a nonapeptide from hemoglobin α1-chain, selectively inhibits CB1 receptors and reduces inflammatory pain.</p>Formule :C55H78F3N13O14Couleur et forme :SolidMasse moléculaire :1202.28
