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Anticorps primaires

Anticorps primaires

Les anticorps primaires sont des immunoglobulines qui se lient spécifiquement à un antigène d'intérêt, permettant la détection et la quantification de protéines, peptides ou autres biomolécules. Ces anticorps sont des outils essentiels dans de nombreuses applications, notamment le Western blot, l'immunohistochimie et l'ELISA. Chez CymitQuimica, nous proposons une vaste sélection d'anticorps primaires de haute qualité, offrant spécificité et sensibilité pour divers besoins de recherche, notamment en cancérologie, immunologie et biologie cellulaire.

Sous-catégories appartenant à la catégorie "Anticorps primaires"

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75324 produits trouvés pour "Anticorps primaires"

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produits par page.
  • Fucα(1-6)GlcNAc-β-propylamido-biotin

    CAS :
    Formule :C27H46N4O12S
    Couleur et forme :Solid
    Masse moléculaire :650.74

    Ref: 3B-F1021

    ne
    À demander
  • AOL-Biotin Conjugate


    Couleur et forme :Colorless to Light yellow clear liquid

    Ref: 3B-A2659

    1ml
    370,00€
  • B Antigen PEG-trifluoroacetamide


    Formule :C28H48F3NO19
    Couleur et forme :Solid
    Masse moléculaire :759.68

    Ref: 3B-B4172

    ne
    À demander
  • N,N-Diethyl-m-toluidine [for Biochemical Research]

    CAS :
    Formule :C11H17N
    Degré de pureté :>99.0%(GC)
    Couleur et forme :Light orange to Yellow to Green clear liquid
    Masse moléculaire :163.26

    Ref: 3B-D3868

    1g
    27,00€
    5g
    46,00€
  • Sialyl Lewis X-Lactose Ethylazide


    Formule :C45H75N5O33
    Degré de pureté :min. 95.0 area%(HPLC)
    Couleur et forme :Solid
    Masse moléculaire :1,214.10

    Ref: 3B-S0922

    ne
    À demander
  • Disialylnonasaccharide-β-pNP

    CAS :
    Formule :C90H141N7O64
    Degré de pureté :>98.0%(HPLC)
    Couleur et forme :White to Light yellow powder to crystal
    Masse moléculaire :2,345.10

    Ref: 3B-N0913

    1mg
    222,00€
  • 6-G1 Glycan

    CAS :
    Formule :C56H94N4O41
    Degré de pureté :min. 95.0 area%(HPLC)
    Couleur et forme :Solid
    Masse moléculaire :1,479.36

    Ref: 3B-G0486

    ne
    À demander
  • Glucoamylase from Rhizopus (contains 50% Diatomaceous earth)

    CAS :
    Couleur et forme :White to Gray to Red powder to crystal

    Ref: 3B-M0035

    25g
    70,00€
  • 3-Amino-9-ethylcarbazole [for Biochemical Research]

    CAS :
    Formule :C14H14N2
    Degré de pureté :>90.0%(T)(HPLC)
    Couleur et forme :Light yellow to Brown to Dark green powder to crystal
    Masse moléculaire :210.28

    Ref: 3B-A2167

    1g
    35,00€
    5g
    75,00€
  • o-Dianisidine [for Biochemical Research]

    CAS :
    Formule :C14H16N2O2
    Degré de pureté :>90.0%(T)
    Couleur et forme :Yellow to Amber to Dark purple powder to crystal
    Masse moléculaire :244.29

    Ref: 3B-D3864

    1g
    27,00€
    5g
    53,00€
  • Streptavidin from Streptomyces avidinii

    CAS :
    Couleur et forme :White to Brown to Dark green powder to crystal

    Ref: 3B-S0951

    1vial
    104,00€
  • Sodium 3-(N-Ethyl-3-methoxyanilino)-2-hydroxy-1-propanesulfonate [for Biochemical Research]

    CAS :
    Formule :C12H18NNaO5S
    Degré de pureté :>98.0%(T)(HPLC)
    Couleur et forme :White to Almost white powder to crystal
    Masse moléculaire :311.33

    Ref: 3B-S0826

    1g
    82,00€
    200mg
    30,00€
  • 5-Bromo-4-chloro-3-indolyl β-D-Glucopyranoside

    CAS :
    Formule :C14H15BrClNO6
    Degré de pureté :>98.0%(HPLC)
    Couleur et forme :White to Light yellow powder to crystal
    Masse moléculaire :408.63

    Ref: 3B-B5393

    1g
    90,00€
    200mg
    33,00€
  • M3(Fuc6)-biotin

    CAS :
    Formule :C53H89N5O32S
    Degré de pureté :min. 95.0 area%(HPLC)
    Couleur et forme :Solid
    Masse moléculaire :1,340.36

    Ref: 3B-M2986

    ne
    À demander
  • Neu5Acα(2-6)Galβ(1-4)GlcNAcβ(1-3)Galβ(1-4)GlcNAc-β-propylamine

    CAS :
    Formule :C42H72N4O29
    Degré de pureté :min. 95.0 area%(HPLC)
    Couleur et forme :Solid
    Masse moléculaire :1,097.04

    Ref: 3B-N1117

    ne
    À demander
  • Galβ(1-3)GalNAc-α-pNP

    CAS :
    Formule :C20H28N2O13
    Degré de pureté :>97.0%(HPLC)
    Couleur et forme :White to Almost white powder to crystal
    Masse moléculaire :504.45

    Ref: 3B-G0375

    5mg
    344,00€
  • Sialylglycopeptide

    CAS :
    Formule :C112H187N15Na2O70
    Degré de pureté :>95.0%(HPLC)
    Couleur et forme :White to Almost white powder to crystal
    Masse moléculaire :2,909.74

    Ref: 3B-S0523

    10mg
    159,00€
  • 4-Nitrophenyl β-D-Glucuronide [Substrate for β-Glucuronidase]

    CAS :
    Formule :C12H13NO9
    Degré de pureté :>98.0%(HPLC)
    Couleur et forme :White to Yellow to Orange powder to crystal
    Masse moléculaire :315.23

    Ref: 3B-N0618

    100mg
    59,00€
  • 4-Nitrophenyl 2-Acetamido-2-deoxy-β-D-glucopyranoside

    CAS :
    Formule :C14H18N2O8
    Degré de pureté :>98.0%(HPLC)(N)
    Couleur et forme :White to Almost white powder to crystal
    Masse moléculaire :342.30

    Ref: 3B-N0866

    1g
    214,00€
    200mg
    76,00€
  • Hyaluronic Acid from Cockscomb

    CAS :
    Couleur et forme :White powder to crystal

    Ref: 3B-H0595

    1g
    365,00€
  • 7-(Diethylamino)coumarin-3-carboxylic Acid

    CAS :
    Formule :C14H15NO4
    Degré de pureté :>98.0%(GC)(T)
    Couleur et forme :Light yellow to Brown powder to crystal
    Masse moléculaire :261.28

    Ref: 3B-D4238

    100mg
    90,00€
  • 5-Bromo-3-indolyl β-D-Galactopyranoside [for Biochemical Research]

    CAS :
    Formule :C14H16BrNO6
    Degré de pureté :>98.0%(HPLC)
    Couleur et forme :White to Almost white powder to crystal
    Masse moléculaire :374.19

    Ref: 3B-B3470

    20mg
    22,00€
    100mg
    60,00€
  • 4-Nitrophenyl Phosphate Di(tris) Salt [Substrate for Phosphatase]

    CAS :
    Formule :C6H6NO6P·(C4H11NO3)2
    Degré de pureté :>90.0%(T)
    Couleur et forme :White to Orange to Green powder to crystaline
    Masse moléculaire :461.36

    Ref: 3B-N0422

    5g
    54,00€
  • Ganglioside GM3(Neu5Gc) (phyto-type)

    CAS :
    Formule :C59H110N2O23
    Degré de pureté :min. 95.0 area%(HPLC)
    Couleur et forme :Solid
    Masse moléculaire :1,215.52

    Ref: 3B-G0510

    ne
    À demander
  • Sodium 3-(N-Ethylanilino)propanesulfonate [for Biochemical Research]

    CAS :
    Formule :C11H16NNaO3S
    Degré de pureté :>98.0%(HPLC)
    Couleur et forme :White to Almost white powder to crystal
    Masse moléculaire :265.30

    Ref: 3B-S0817

    1g
    97,00€
    200mg
    35,00€
  • SGN

    CAS :
    Formule :C88H144N8O64
    Degré de pureté :>90.0%(HPLC)
    Couleur et forme :White to Light yellow powder to crystal
    Masse moléculaire :2,338.11

    Ref: 3B-G0560

    1mg
    148,00€
  • L-(-)-Fucose

    CAS :
    Formule :C6H12O5
    Degré de pureté :>97.0%(HPLC)
    Couleur et forme :White to Almost white powder to crystal
    Masse moléculaire :164.16

    Ref: 3B-F0065

    1g
    41,00€
    10g
    236,00€
  • Neu5Gcα(2-6) N-Glycan

    CAS :
    Formule :C84H138N6O64
    Degré de pureté :min. 95.0 area%(HPLC)
    Couleur et forme :Solid
    Masse moléculaire :2,256.01

    Ref: 3B-N1064

    ne
    À demander
  • 6-Carboxyfluorescein

    CAS :
    Formule :C21H12O7
    Degré de pureté :>97.0%(HPLC)
    Couleur et forme :Light yellow to Brown powder to crystal
    Masse moléculaire :376.32

    Ref: 3B-C2478

    100mg
    104,00€
  • GlcNAcβ(1-4)[Fucα(1-6)]GlcNAc

    CAS :
    Formule :C22H38N2O15
    Degré de pureté :>98.0%(HPLC)
    Couleur et forme :White to Almost white powder to crystal
    Masse moléculaire :570.55

    Ref: 3B-G0423

    2mg
    366,00€
    5mg
    749,00€
  • Potassium Hyaluronate from Cockscomb

    CAS :
    Couleur et forme :White to Almost white powder to crystal

    Ref: 3B-H0652

    1g
    426,00€
  • 5-Carboxyfluorescein

    CAS :
    Formule :C21H12O7
    Degré de pureté :>97.0%(T)(HPLC)
    Couleur et forme :Light yellow to Brown powder to crystal
    Masse moléculaire :376.32

    Ref: 3B-C2477

    100mg
    93,00€
  • HSA-Globo-H


    Couleur et forme :White to Almost white powder to crystal

    Ref: 3B-H1794

    1vial
    557,00€
  • Gentiobiose

    CAS :
    Formule :C12H22O11
    Degré de pureté :>96.0%(HPLC)
    Couleur et forme :White to Almost white powder to crystal
    Masse moléculaire :342.30

    Ref: 3B-G0026

    100mg
    92,00€
  • 5-Aminofluorescein (isomer I)

    CAS :
    Formule :C20H13NO5
    Degré de pureté :>95.0%(T)(HPLC)
    Couleur et forme :Orange to Brown to Dark red powder to crystal
    Masse moléculaire :347.33

    Ref: 3B-A0306

    1g
    110,00€
    5g
    408,00€
  • Galacto-N-biose

    CAS :
    Formule :C14H25NO11
    Degré de pureté :min. 95.0 area%(HPLC)
    Couleur et forme :White to Almost white powder to crystal
    Masse moléculaire :383.35

    Ref: 3B-G0439

    ne
    À demander
  • Fucα(1-2)Galβ(1-3)GalNAc-β-pNP (=H type 3 β-pNP Glycoside)


    Formule :C26H38N2O17
    Couleur et forme :Solid
    Masse moléculaire :650.59

    Ref: 3B-F0896

    ne
    À demander
  • N-(2-Hydroxy-3-sulfopropyl)-3,5-dimethoxyaniline Sodium Salt [for Biochemical Research]

    CAS :
    Formule :C11H16NNaO6S
    Degré de pureté :>98.0%(HPLC)
    Couleur et forme :White to Light yellow to Light orange powder to crystal
    Masse moléculaire :313.30

    Ref: 3B-S0827

    200mg
    75,00€
  • A Antigen PEG-trifluoroacetamide


    Formule :C30H51F3N2O19
    Couleur et forme :Solid
    Masse moléculaire :800.73

    Ref: 3B-A2631

    ne
    À demander
  • Sodium 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonate

    CAS :
    Formule :C12H18NNaO4S
    Degré de pureté :>98.0%(HPLC)
    Couleur et forme :White to Almost white powder to crystal
    Masse moléculaire :295.33

    Ref: 3B-S0805

    1g
    23,00€
    5g
    60,00€
  • Galβ(1-3)GlcNAc[6S]β(1-3)Galβ(1-4)GlcNAc[6S]-β-PEG3-biotin


    Formule :C49H82N6Na2O33S3
    Degré de pureté :min. 95.0 area%(HPLC)
    Couleur et forme :Solid
    Masse moléculaire :1,425.36

    Ref: 3B-G0514

    ne
    À demander
  • Sialyl Lewis X-Lactose Ethylamine


    Formule :C45H77N3O33
    Degré de pureté :min. 95.0 area%(HPLC)
    Couleur et forme :Solid
    Masse moléculaire :1,188.10

    Ref: 3B-S0923

    ne
    À demander
  • DIAC rabbit pAb


    Chitobiase is a lysosomal glycosidase involved in degradation of asparagine-linked oligosaccharides on glycoproteins (Aronson and Kuranda, 1989 [PubMed 2531691]).[supplied by OMIM, Nov 2010],

    Ref: EK-ES11136

    50µl
    188,00€
    100µl
    316,00€
  • PIP rabbit pAb


    induction:By prolactin and androgen; inhibited by estrogen.,similarity:Belongs to the PIP family.,subunit:Monomer. Interacts with AZGP1.,tissue specificity:Expressed in pathological conditions of the mammary gland and in several exocrine tissues, such as the lacrimal, salivary, and sweat glands.,

    Ref: EK-ES11389

    50µl
    188,00€
    100µl
    316,00€
  • TFIIE-β rabbit pAb


    function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.,similarity:Belongs to the TFIIE beta subunit family.,similarity:Contains 1 TFIIE beta DNA-binding domain.,subunit:Tetramer of two alpha and two beta chains. Interacts with FACT subunit SUPT16H.,

    Ref: EK-ES3587

    50µl
    188,00€
    100µl
    316,00€
  • RIPK4 rabbit pAb


    The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. [provided by RefSeq, Jul 2008],

    Ref: EK-ES13389

    50µl
    188,00€
    100µl
    316,00€
  • INSL6 rabbit pAb


    The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. This gene is preferentially expressed in testis. Its expression in testis is restricted to interstitial cells surrounding seminiferous tubules, which suggests a role in sperm development and fertilization. [provided by RefSeq, Jul 2008],

    Ref: EK-ES10714

    50µl
    188,00€
    100µl
    316,00€
  • Ref: EK-ES16811

    50µl
    188,00€
    100µl
    316,00€
  • LEO1 rabbit pAb


    LEO1, parafibromin (CDC73; MIM 607393), CTR9 (MIM 609366), and PAF1 (MIM 610506) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]).[supplied by OMIM, Mar 2008],

    Ref: EK-ES15170

    50µl
    188,00€
    100µl
    316,00€
  • Ref: EK-ES13370

    50µl
    188,00€
    100µl
    316,00€
  • Cortactin (phospho Tyr466) rabbit pAb


    cortactin(CTTN) Homo sapiens This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010],

    Ref: EK-ES1500

    50µl
    188,00€
    100µl
    316,00€
  • KCNT1 rabbit pAb


    Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],

    Ref: EK-ES6922

    50µl
    188,00€
    100µl
    316,00€
  • HSP70L rabbit pAb


    This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008],

    Ref: EK-ES2575

    50µl
    188,00€
    100µl
    316,00€
  • MPP2 rabbit pAb


    Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. [provided by RefSeq, Jul 2008],

    Ref: EK-ES14720

    50µl
    188,00€
    100µl
    316,00€
  • SENP3 rabbit pAb


    The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009],

    Ref: EK-ES5470

    50µl
    188,00€
    100µl
    316,00€
  • Ref: EK-ES16610

    50µl
    188,00€
    100µl
    316,00€
  • VATA rabbit pAb


    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all

    Ref: EK-ES10453

    50µl
    188,00€
    100µl
    316,00€
  • Ref: EK-ES19333

    50µl
    188,00€
    100µl
    316,00€
  • SNAPC 19 rabbit pAb


    This gene encodes a subunit of the small nuclear RNA (snRNA)-activating protein complex that plays a role in the transcription of snRNA genes. This complex binds to the promoters of snRNA genes transcribed by either RNA polymerase II or III and recruits other regulatory factors to activate snRNA gene transcription. The encoded protein may play a role in stabilizing this complex. A pseudogene of this gene has been identified on chromosome 6. [provided by RefSeq, Jul 2016],

    Ref: EK-ES4460

    50µl
    188,00€
    100µl
    316,00€
  • BTF rabbit pAb


    This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

    Ref: EK-ES1797

    50µl
    188,00€
    100µl
    316,00€
  • AP-2α/β rabbit pAb


    transcription factor AP-2 alpha(TFAP2A) Homo sapiens The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009],

    Ref: EK-ES1670

    50µl
    188,00€
    100µl
    316,00€
  • TRI56 rabbit pAb


    sequence caution:Translation N-terminally extended.,sequence caution:Translation N-terminally shortened.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 2 B box-type zinc fingers.,

    Ref: EK-ES11446

    50µl
    188,00€
    100µl
    316,00€
  • EGFR (phospho Ser1026) rabbit pAb


    The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016],

    Ref: EK-ES5058

    50µl
    188,00€
    100µl
    316,00€
  • ZN441 rabbit pAb


    function:May be involved in transcriptional regulation.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 19 C2H2-type zinc fingers.,

    Ref: EK-ES10616

    50µl
    188,00€
    100µl
    316,00€
  • CBPB1 rabbit pAb


    Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008],

    Ref: EK-ES9501

    50µl
    188,00€
    100µl
    316,00€
  • IRX3 rabbit pAb


    IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM, Aug 2009],

    Ref: EK-ES7570

    50µl
    188,00€
    100µl
    316,00€
  • Ref: EK-ES12544

    50µl
    188,00€
    100µl
    316,00€
  • RRP22 rabbit pAb


    similarity:Belongs to the small GTPase superfamily. Ras family.,

    Ref: EK-ES4527

    50µl
    188,00€
    100µl
    316,00€
  • TFCP2 rabbit pAb


    This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene. The encoded protein regulates erythroid gene expression, plays a role in the transcriptional switch of globin gene promoters, and it activates many other cellular and viral gene promoters. The gene product interacts with certain inflammatory response factors, and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease. [provided by RefSeq, Mar 2010],

    Ref: EK-ES12752

    50µl
    188,00€
    100µl
    316,00€
  • Ref: EK-ES18895

    50µl
    188,00€
    100µl
    316,00€
  • Ref: EK-ES18932

    50µl
    188,00€
    100µl
    316,00€
  • Akt (Phospho-Ser129) Antibody


    The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]

    Ref: EK-ES8876

    50µl
    188,00€
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    316,00€
  • Ref: EK-ES17170

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  • ALS rabbit pAb


    The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],

    Ref: EK-ES5855

    50µl
    188,00€
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  • I17RD rabbit pAb


    This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016],

    Ref: EK-ES10701

    50µl
    188,00€
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    316,00€
  • ADAM32 rabbit pAb


    ADAM metallopeptidase domain 32(ADAM32) Homo sapiens This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015],

    Ref: EK-ES1598

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    188,00€
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  • Ref: EK-ES12987

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  • ACADL rabbit pAb


    The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008],

    Ref: EK-ES18504

    50µl
    188,00€
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  • HXA10 rabbit pAb


    In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 (HOXA9) gene. [provided by RefSeq, Mar 2011],

    Ref: EK-ES15551

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  • ATOH7 rabbit pAb


    This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment. [provided by RefSeq, Dec 2011],

    Ref: EK-ES11917

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    188,00€
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    316,00€
  • Ref: EK-ES19546

    50µl
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    316,00€
  • Ref: EK-ES17000

    50µl
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  • LAT (Phospho Tyr255) rabbit pAb


    function:Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.,miscellaneous:Engagement of killer inhibitory receptors (KIR) disrupts the interaction of PLCG1 with LAT and blocks target cell-induced activation of PLC, maybe by inducing the dephosphorylation of LAT.,PTM:Palmitoylation of Cys-26 and Cys-29 is required for raft targeting and efficient phosphorylation.,PTM:Phosphorylated on tyrosines by ZAP-70 upon TCR activation, or by SYK upon other immunoreceptor activation; which leads to the recruitment of multiple signaling molecules. Is one of the most prominently tyrosine-phosphorylated proteins detected following TCR engagement.,subcellular location:Present in lipid rafts.,subunit:When phosphorylated, interacts directly with the PIK3R1 subunit of phosphoinositide 3-kinase and the SH2 domains of GRB2, GRAP, GRAP2, PLCG1 and PLCG2. Interacts indirectly with CBL, SOS, VAV, and LCP2. Interacts with SHB, SKAP2 and CLNK (By similarity). Interacts with FCGR1A.,tissue specificity:Expressed in thymus, T-cells, NK cells, mast cells and, at lower levels, in spleen. Present in T-cells but not B-cells (at protein level).,

    Ref: EK-ES20193

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  • IκB-ε (phospho Ser22) rabbit pAb


    The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. [provided by RefSeq, Sep 2011],

    Ref: EK-ES6386

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    188,00€
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  • Ref: EK-ES18885

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  • Tau (phospho-Ser202) rabbit pAb


    This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008],

    Ref: EK-ES12812

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  • Ref: EK-ES12840

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  • 53BP1 (phospho Ser6) rabbit pAb


    function:May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.,PTM:Asymmetrically dimethylated on Arg residues by PRMT1. Methylation is required for DNA binding.,PTM:Phosphorylated at basal level in the absence of DNA damage. Hyper-phosphorylated in an ATM-dependent manner in response to DNA damage induced by ionizing radiation. Hyper-phosphorylated in an ATR-dependent manner in response to DNA damage induced by UV irradiation.,similarity:Contains 2 BRCT domains.,subcellular location:Associated with kinetochores. Both nuclear and cytoplasmic in some cells. Recruited to sites of DNA damage, such as double stand breaks. Methylation of histone H4 at 'Lys-20' is required for efficient localization to double strand breaks.,subunit:Interacts with IFI202A (By similarity). Binds to the central domain of TP53/p53. May form homo-oligomers. Interacts with DCLRE1C. Interacts with histone H2AFX and this requires phosphorylation of H2AFX on 'Ser-139'. Interacts with histone H4 that has been dimethylated at 'Lys-20'. Has low affinity for histone H4 containing monomethylated 'Lys-20'. Does not bind histone H4 containing unmethylated or trimethylated 'Lys-20'. Has low affinity for histone H3 that has been dimethylated on 'Lys-79'. Has very low affinity for histone H3 that has been monomethylated on 'Lys-79' (in vitro). Does not bind unmethylated histone H3.,

    Ref: EK-ES7435

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  • ANXA5 rabbit pAb


    The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa. [provided by RefSeq, Jul 2008],

    Ref: EK-ES11272

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  • Ref: EK-ES12066

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  • Cleaved-Integrin α5 LC (E895) rabbit pAb


    integrin subunit alpha 5(ITGA5) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],

    Ref: EK-ES1062

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    188,00€
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    316,00€
  • TIS11B (phospho Ser92) rabbit pAb


    This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

    Ref: EK-ES7293

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  • KERA rabbit pAb


    The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2).[provided by RefSeq, May 2010],

    Ref: EK-ES15334

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    188,00€
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    316,00€
  • Ref: EK-ES15860

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  • Vitronectin rabbit pAb


    The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. [provided by RefSeq, Jul 2008],

    Ref: EK-ES7512

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  • Ref: EK-ES20083

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    316,00€
  • GRK 1 rabbit pAb


    This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq, Jul 2008],

    Ref: EK-ES2476

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    188,00€
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    316,00€
  • POGZ rabbit pAb


    pogo transposable element with ZNF domain(POGZ) Homo sapiens The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2010],

    Ref: EK-ES10594

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    188,00€
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    316,00€
  • eEF2K (phospho Ser366) rabbit pAb


    This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008],

    Ref: EK-ES1470

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    316,00€
  • GSTM2 rabbit pAb


    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq, Jul 2008],

    Ref: EK-ES11906

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    188,00€
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    316,00€