Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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N1-Methyladenosine-5’-monophosphate
CAS :The N1-methyladenosine is a reversible modification in tRNA, mRNA and long non-coding RNAFormule :C11H16N5O7PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :361.25 g/molKinetin riboside
CAS :Kinetin is a plant hormone that regulates cell proliferation and differentiation. Kinetin riboside is a derivative of kinetin in which the ribose moiety has been converted to ribosyl-ribitol. Kinetin riboside has shown the ability to inhibit cancer cells by inducing apoptosis, which may be related to its ability to inhibit cyclin D2 and mitochondrial membrane potential. In addition, kinetin riboside has been shown to protect against oxidative stress and decrease mitochondrial function in cells. This compound may have therapeutic potential for cancer treatment and other diseases caused by oxidative stress or mitochondrial dysfunction.Formule :C15H17N5O5Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :347.33 g/molCapecitabine
CAS :<p>Pro-drug of 5-FU; anti-cancer agent</p>Formule :C15H22FN3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :359.35 g/molN-Cbz gemcitabine
CAS :N-Cbz gemcitabine is a novel nucleoside analog that is chemically modified to be activated by enzymes in the cell. It has been shown to have high purity and high quality. In addition, N-Cbz gemcitabine is an anticancer drug that is most effective against cells with a low number of nucleotides per cell. This drug has shown antiviral properties and is used for the treatment of HIV/AIDS patients.Formule :C17H17F2N3O6Degré de pureté :Min. 95%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :397.33 g/mol2-Thiocytidine
CAS :<p>2-Thiocytidine is a nucleoside that is an intermediate in the synthesis of thiamine. It has been shown to be effective in the treatment of prostate cancer cells, which may be due to its ability to inhibit protein synthesis. 2-Thiocytidine binds to the catalytic site of ribonucleotide reductase (RR) and inhibits the enzyme's activity, thereby inhibiting DNA synthesis. This drug also has been shown to inhibit crosslinking caused by UV light or other agents that generate reactive oxygen species. 2-Thiocytidine binds to the active site of RR and prevents the formation of the enzyme-substrate complex. This binding prevents reduction of ribose into ribonucleotides and inhibits DNA synthesis.</p>Formule :C9H13N3O4SDegré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :259.28 g/molN6-Etheno 2'-deoxyadenosine
CAS :<p>N6-Etheno 2'-deoxyadenosine is a nucleoside analogue that inhibits DNA synthesis by binding to the enzyme thymidylate synthase, which catalyzes the conversion of deoxyuridine monophosphate to thymidine monophosphate. This drug has been shown to be genotoxic in vitro and in vivo, as evidenced by its ability to induce chromosomal aberrations in cultured human lymphocytes and disrupt DNA replication in mammalian cells. It also reacts with mismatched base pairs and dna duplexes, leading to their degradation. N6-Etheno 2'-deoxyadenosine binds reversibly to antibodies and can be detected using an analytical method that employs monoclonal antibodies.</p>Formule :C12H13N5O3Couleur et forme :White Off-White PowderMasse moléculaire :275.26 g/mol3',5'-Di-O-acetyl-2'-deoxy-5-iodouridine
CAS :<p>3',5'-Di-O-acetyl-2'-deoxy-5-iodouridine is an inorganic, deoxyribonucleoside. It is the acetyl derivative of 2'-deoxy-5-iodouridine, which is an analog of uracil. 3',5'-Di-O-acetyl-2'-deoxy-5-iodouridine has been shown to have antiviral properties against herpes simplex virus type 1 (HSV1) and herpes simplex virus type 2 (HSV2) in animals. This drug also has antiangiogenic properties, inhibiting the growth of new blood vessels and tissues at the site of a tumour. Studies have shown that 3',5'-di-O acetyl 2'-deoxyuridine can be incorporated into exudates from human cancer patients and can inhibit tumor cell proliferation in vivo.</p>Formule :C13H15IN2O7Degré de pureté :Min. 95%Masse moléculaire :438.18 g/mol2′-O-(2-Methoxy-2-oxoethyl)-5-methyl-uridine
CAS :2′-O-(2-Methoxy-2-oxoethyl)-5-methyl-uridine is a nucleoside that can be used as an anticancer drug and antiviral agent. It has shown potent in vitro cytotoxic activity against human leukemia cells and other cancer cell lines, including breast, prostate, ovarian, and colon cancers. 2′-O-(2-Methoxy-2-oxoethyl)-5-methyl-uridine also has good antiherpetic potential. This compound is a novel and synthetic nucleoside with high purity, high quality, and excellent stability. It is soluble in water, methanol, ethanol, acetone, acetonitrile; slightly soluble in chloroform; insoluble in ether or hexane. CAS No. 149301-23-5Formule :C13H18N2O8Degré de pureté :Min. 95%Masse moléculaire :330.29 g/mol5-Chloro-2',3'-dideoxy-3'-fluorouridine
CAS :<p>5-Chloro-2',3'-dideoxy-3'-fluorouridine is a nucleoside analog that inhibits the replication of HIV by competing with other nucleosides for incorporation into viral DNA, thereby inhibiting the production of new viruses. This drug has been shown to have an inhibitory effect on the replication of HIV and has been approved as an antiretroviral agent. 5-Chloro-2',3'-dideoxy-3'-fluorouridine is active against most HIV strains and is able to suppress viral load in patients with chronic hepatitis B or C. It also inhibits the hepatic metabolism of drugs metabolized by cytochrome P450 enzymes, such as CYP3A4 inducers. The effective dose for this drug ranges from 100 mg to 200 mg per day.</p>Formule :C9H10ClFN2O4Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :264.64 g/mol2-Amino-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
CAS :2-Amino-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a protected nucleoside analog.In this compound the sugar’s hydroxyl groups are acetylated to make it chemically stable and reactive in nucleoside chemistry.Degré de pureté :Min. 95%2′-O-[2-(Methylamino)-2-oxoethyl]adenosine
CAS :2′-O-[2-(Methylamino)-2-oxoethyl]adenosine is a nucleoside that can be used as an anticancer, antiviral, and anticoagulant. It is synthesized from the natural nucleosides adenosine and cytidine. 2′-O-[2-(Methylamino)-2-oxoethyl]adenosine has been shown to inhibit the growth of tumor cells in vitro. This compound also inhibits viral replication by inhibiting DNA synthesis through inhibition of ribonucleotide reductase and deoxyribonucleotide reductase. 2′-O-[2-(Methylamino)-2-oxoethyl]adenosine is phosphorylated by ATP to produce 2′-O-[2-(methylamino)-2-oxoethyl]adenosinophosphate (AMP). AMP then binds to the purinergic receptor P1, which leads toFormule :C13H18N6O5Degré de pureté :Min. 95%Masse moléculaire :338.32 g/mol1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)-5-iodouracil
1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-iodouracil is a modified nucleoside analog for research applications. It contains a uracil base with an iodine atom, a fluorinated sugar that produces increased metabolic stability and benzoyl-protecting groups at the 3'- and 5'-hydroxyl positions, commonly used in nucleoside synthesis.Degré de pureté :Min. 95%N6-Benzoyl-2'-O-methyladenosine
CAS :N6-Benzoyl-2'-O-methyladenosine is a nucleoside that is chemically synthesized. It has been shown to be an inhibitor of the polyhedrosis virus, which causes an infectious disease in silkworms. N6-Benzoyl-2'-O-methyladenosine also inhibits viral replication by interfering with the synthesis of messenger RNA. This compound can be used as a silver nitrate or silver salt prodrug for treating diseases caused by viruses and bacteria. This drug is not active against DNA viruses because it does not possess phosphate groups on its structure.Formule :C18H19N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :385.37 g/mol2'-Deoxy-2'-fluoroadenosine-5'-triphosphate tetralithium salt
CAS :2'-Deoxy-2'-fluoroadenosine-5'-triphosphate tetralithium salt (FdATP) is a competitive inhibitor of ATP. It inhibits the synthesis of RNA, DNA, and protein in cell culture at high concentrations. FdATP is also an analog of adenosine triphosphate (ATP), which is needed for cellular energy production. The competitive inhibition of ATP by FdATP prevents the formation of a phosphorylated enzyme that is required for the initiation of DNA synthesis. This can lead to cell death, as the cells cannot produce proteins required for growth and replication.Formule :C10H11FN5O12P3•Li4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :532.9 g/mol2'-Deoxyadenosine monohydrate
CAS :<p>2'-Deoxyadenosine monohydrate (2'-dA) is an adenosine nucleotide that is synthesized by the enzyme adenosine kinase. It is a competitive inhibitor of phosphodiesterase and inhibits the activity of this enzyme, which breaks down cyclic nucleotides to their corresponding monophosphate form. This leads to elevated levels of cAMP, which can cause neuronal death by apoptosis. 2'-dA has been shown to have sublethal effects on neurons at concentrations that are below those required for neuronal death and apoptosis. This may be due to its ability to inhibit the synthesis of ATP, thereby limiting the production of phosphoryl groups from ATP. The inhibition of ATP synthesis also reduces the amount of energy available for other processes within cells.</p>Formule :C10H13N5O3•H2ODegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :269.26 g/mol5'-O-tert-Butyldiphenylsilyl-thymidine
CAS :<p>5'-O-tert-Butyldiphenylsilyl-thymidine (TBS-T) is a class of nucleoside that is synthesized by condensation of two molecules of 5'-O-tert-butyldiphenylsilyl-2',3'-dideoxyuridine (TBDPS) and N6-benzoyladenine. TBS-Ts are used in the synthesis of phosphorothioate oligodeoxynucleotides. They have been shown to be useful as activators for the formation of phosphite linkages at the 3' terminus of DNA oligonucleotides. TBS-T is also used in other applications, such as the preparation of diastereomerically pure nucleosides for use in chemical reactions.</p>Formule :C26H32O5N2SiDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :480.63 g/molThymidine 3′-monophosphate disodium
CAS :<p>Thymidine 3′-monophosphate disodium is a chemotherapeutic agent that has been shown to have antiviral and anticancer properties. It is a nucleoside analogue, which mimics the structure of thymidine and inhibits DNA synthesis by interfering with the DNA replication process. Thymidine 3′-monophosphate disodium is also used as an activator in the synthesis of deoxyribonucleosides and ribonucleosides. This product is synthetic, high quality, and not chemically modified. It has CAS number 68698-19-1 and molecular weight of 242.06 g/mol.</p>Formule :C10H15N2O8P•Na2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :368.19 g/mol5'-O-DMT-thymidine 3'-O-succinate triethylammonium salt
CAS :5'-O-DMT-thymidine 3'-O-succinate triethylammonium salt is a novel antiviral agent that inhibits viral replication by competing with natural nucleosides for incorporation into the viral DNA or RNA. The 5'-O-DMT group prevents the elimination of thymidine from the monophosphate form. This product has a high purity and quality, as well as potent antiviral activity against HIV and other viruses.Formule :C35H36N2O10·xC6H15NDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :745.86 g/mol2-Methylthioadenosine
CAS :<p>2-Methylthioadenosine is a purine nucleoside which induces necrotic cell death. It is the first of its kind to be shown to have activity against squamous carcinoma cells, and is activated by nucleoside phosphorylase in order to produce its cytotoxic form. 2-Methylthioadenosine also inhibits the transcription-polymerase chain reaction and increases oxidative injury. This drug has been shown to have receptor activity in brain cells, as well as chemotactic activity for gland cells. 2-Methylthioadenosine has been used as a model organism for polymerase chain reactions, and has been shown to inhibit p2y receptors in the human colon cancer cell line HT29.</p>Formule :C11H15N5O4SDegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :313.34 g/mol5'-O-(4,4'-Dimethoxytrityl)adenosine
CAS :<p>5'-O-(4,4'-Dimethoxytrityl)adenosine is a phosphoramidite that can be used as an activator for the synthesis of DNA. It is also used in the preparation of modified nucleosides and has anticancer activity. 5'-O-(4,4'-Dimethoxytrityl)adenosine is a modified ribonucleoside with high quality and high purity. This product has been shown to have antiviral activity against HIV-1.</p>Formule :C31H31N5O6Degré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :569.61 g/mol
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