Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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3'-Azido-N4-benzoyl-2',3'-dideoxycytidine
CAS :<p>3'-Azido-N4-benzoyl-2',3'-dideoxycytidine is a novel nucleoside analog with antiviral and anticancer activities. It is used for the treatment of HIV, hepatitis B and C, herpes, and influenza. 3'-Azido-N4-benzoyl-2',3'-dideoxycytidine has been shown to inhibit the proliferation of cells in culture and to induce apoptosis in various cancer cell lines.<br>The synthesis of 3'-azido-N4-benzoyl-2',3'-dideoxycytidine starts with the condensation of 4-(hydroxymethyl)phenylacetic acid (1) with 2,6-dichloroisonicotinic acid chloride (2) in the presence of triethylamine to give 4-(hydroxymethyl)phenylacetic acid chloride (3). The N4 benzoyl</p>Formule :C16H16N6O4Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :356.34 g/mol6-Chloro-9-(2'-deoxy-3',5'-di-O-toluoyl-b-ribofuranosyl)purine
CAS :<p>6-Chloro-9-(2'-deoxy-3',5'-di-O-toluoyl-b-ribofuranosyl)purine is a synthetic nucleoside with antiviral and anticancer activity. It is an activator of the DNA polymerase, which is involved in the synthesis of DNA. The high purity of this product makes it a good choice for use in research or as a starting material for further chemical modification. 6-Chloro-9-(2'-deoxy-3',5'-di-O-toluoyl-b-ribofuranosyl)purine has been shown to inhibit the growth of cancer cells, including breast, lung and colon carcinoma cells.</p>Formule :C26H23ClN4O5Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :506.95 g/molN4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
CAS :<p>N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a modified nucleoside with anticancer and antiviral properties. It is used in the synthesis of oligonucleotides as an activator, DNA or RNA. This product is also used as a phosphoramidite for the preparation of oligonucleotides. N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT cytidine has a CAS Number of 8125687.</p>Formule :C43H49N3O8SiDegré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :763.95 g/molN6-Benzoyl-5'-O-DMT-2'-O-methyladenosine
CAS :<p>N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine is a novel nucleoside that is structurally related to adenosine. It is synthesized through the reaction of N6-benzoyladenine with 2'-O-methyladenosine. This nucleoside has been shown to be an effective antiviral and anticancer agent.</p>Formule :C39H37N5O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :687.76 g/mol8-Bromoadenosine 3',5'-cyclic monophosphate
CAS :8-Bromoadenosine 3',5'-cyclic monophosphate (8-Br-cAMP) is a cyclic nucleotide that is involved in the regulation of energy metabolism. It is a pharmacological agent that regulates the intracellular levels of cAMP and plays an important role in regulating cell proliferation, differentiation, and survival. 8-Br-cAMP binds to specific protein kinases and alters their activity. It also inhibits the enzymatic activity of DNA polymerase II. 8-Br-cAMP has been shown to inhibit tumor growth in mice with bone cancer. The mechanism by which this drug exerts its antitumor effect appears to be related to increased expression of basic proteins and decreased expression of phosphatase 2A, leading to increased activation of protein kinase A. 8-Br-cAMP also causes cellular accumulation of Ca2+ ions by stimulating an increase in the activity of phospholipase C, which hydrolyzes phosphatFormule :C10H11BrN5O6PDegré de pureté :Min. 98 Area-%Couleur et forme :Beige PowderMasse moléculaire :408.11 g/mol1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N8-(dimethylamino)methyleneguanidin-1-yl)-D-altro-hexitol
CAS :1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N8-(dimethylamino)methyleneguanidin-1-yl)-D-altro-hexitol is a synthetic, protected nucleoside analog built on a D-altro-hexitol backbone — which is a six-carbon sugar alcohol structure — and it includes a highly modified guanidine-like base at the 2-position. It has possible applications in synthetic nucleic acid chemistryFormule :C28H28N6O6Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :544.57 g/molP1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate sodium salt
CAS :<p>P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate sodium salt is an intermediate in the biosynthesis of ATP. It is also a cofactor for adenylate kinase and pyruvate kinase. The synthesis of this compound takes place in human serum and requires the enzyme synthetase as well as sephadex g-100. Synthetase catalyzes the condensation of ATP with 5-AMP to yield P1-(5'-adenosyl) P3-(5'-adenosyl) triphosphate sodium salt. This reaction is reversible, and can be catalyzed by phosphohydrolases that hydrolyze ATP to AMP and inorganic phosphate. The physiological function of this compound is not yet clear, but it has been shown to increase intracellular Ca2+ levels in cardiac cells, leading to congestive heart failure. This compound has low potency, so it does not have any</p>Formule :C20H27N10O16P3•(Na)xDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :756.41 g/mol3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine
CAS :<p>3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine is a nucleoside monophosphate with antiviral activity. It is a synthetic nucleoside that has been modified to be resistant to degradation by ribonucleases. 3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine inhibits the synthesis of DNA, RNA and protein and is used for treatment of cancer. This drug is not active against other types of viruses such as herpes simplex virus or cytomegalovirus.</p>Formule :C13H15FN2O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :330.27 g/mol5'-Amino-5'-deoxyadenosine hydrochloride
CAS :<p>5'-Amino-5'-deoxyadenosine hydrochloride (5'-ADeA) is a nucleotide that is synthesized from ribose 5-phosphate and adenosine monophosphate. It has been shown to have potential as a biomarker for skin cancer. The synthesis of 5'-ADeA is catalyzed by the enzyme caffeic acid 4-monooxygenase, which converts caffeic acid into 5'-ADeA. This reaction requires molecular oxygen, NADPH, and iron ions. The activity of this enzyme can be inhibited by sodium carbonate or basic fibroblast growth factor (bFGF). This drug has been shown to have anti-inflammatory effects in vivo.</p>Formule :C10H14N6O3Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :266.26 g/molAdenosine 3',5'-cyclic monophosphate sodium salt
CAS :<p>Second messenger in intracellular signal transduction</p>Formule :C10H11N5NaO6PDegré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :351.19 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-O-succinate triethylamine salt
CAS :<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-O-succinate triethylamine salt is a synthetic antiviral agent that can be used in the treatment of HIV. This drug inhibits the viral DNA polymerase and prevents virus replication. N4-Benzoyl-2'-deoxy-5'-O-DMT cytidine 3'-O succinate triethylamine salt is a novel nucleoside analogue with a monophosphate group at the 5' position and an N4 benzoyl group at the 2' position. It is an activator of DNA synthesis, which can be used for cancer chemotherapy. The chemical name for this drug is CAS No. 74405-44-0 (free base).</p>Formule :C41H39N3O10·C6H15NDegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :834.95 g/mol8-Azidoadenosine 3',5'-cyclic monophosphosphate free acid
CAS :<p>8-Azidoadenosine 3',5'-cyclic monophosphosphate is used for nucleotide labelling via a click reaction involving the azide moiety and a terminal alkyne conjugated to a label. The reaction generates a stable nucleotide labelled adduct containing a triazole link.</p>Formule :C10H11N8O6PDegré de pureté :Min. 95%Couleur et forme :White to pale yellow solid.Masse moléculaire :370.22 g/molXanthosine
CAS :Produit contrôlé<p>Xanthosine is a purine nucleoside that is formed from the metabolism of adenosine. Xanthosine can be phosphorylated to form xanthosine 5'-monophosphate (XMP), which has been shown to have biochemical properties and metabolic responses in vitro. The p-hydroxybenzoic acid moiety of xanthosine has been shown to have therapeutic potential for the treatment of inflammatory diseases, such as rheumatoid arthritis. It also has a role in the regulation of disease activity, as it is found at high concentrations in human serum, and regulates the proliferation of cells through its binding to nuclear proteins. Xanthosine is an important component of dinucleotide phosphate (NDP) pools that are essential for cell nuclei function. NDPs are also important for DNA synthesis and repair, as well as protein synthesis. Xanthosine 5'-monophosphate can act as a metal chelate and is used in</p>Formule :C10H12N4O6Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :284.23 g/moltrans-Zeatin-o-glucoside riboside
CAS :<p>Trans-Zeatin-o-glucoside riboside is a nucleotide that is found in protonemata and is involved in the regulation of cell division, cytokinin production, and responses to light. It is a cytokinin that regulates the pathways of nitrogen metabolism and other metabolic pathways. Trans-Zeatin-o-glucoside riboside has been detected at detectable levels in cells, tissues, and fluids. It has been shown to be involved in the evolution of plants. It has been shown to regulate cell division by inhibiting the phosphorylation of fibrillarin protein kinase, which leads to an increase in cyclins D1/D2 with no change in cyclin E1/E2. This nucleotide may also play a role in regulating cytokinin production by binding to DNA and influencing gene transcription.</p>Formule :C21H31N5O10Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :513.5 g/mol3'-O-Allyladenosine
CAS :<p>3'-O-Allyladenosine is an antiviral agent that inhibits the replication of DNA and RNA viruses. It has been shown to have anticancer properties, and is a novel nucleoside analog with potential as an antitumor agent. 3'-O-Allyladenosine is a modified nucleoside analog that can be synthesized with high purity and quality. This compound has shown antiviral activity against influenza virus and herpes simplex virus type 1. In addition, 3'-O-Allyladenosine has been found to inhibit tumor growth in mice without any significant side effects.</p>Formule :C13H17N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :307.31 g/mol8-Azidoadenosine
CAS :<p>8-Azidoadenosine is an adenosine analogue conjugated with an azido group which can be used for oligonucleotide labelling. The azido group reacts with a terminal alkyne via a click reaction, forming the labelled nucleotide containing a triazole linker.</p>Formule :C10H12N8O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :308.25 g/molRibavirin 5'-diphosphate lithium
CAS :<p>Ribavirin is an antiviral drug that inhibits the production of viral RNA. Ribavirin 5'-diphosphate is formed in the liver through sequential actions of kinases.</p>Formule :C8H14N4O11P2•Li2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :418.03 g/molN4,3'-O-Dibenzoyl-2'-deoxycytidine
CAS :<p>N4,3'-O-Dibenzoyl-2'-deoxycytidine is a nucleoside that functions as a base. It is a diester of the naturally occurring nucleoside cytidine and 2′,6′-dibenzoyl-deoxyribose. The compound has been shown to be an inhibitor of DNA polymerases and nuclease activity in vitro. N4,3'-O-Dibenzoyl-2'-deoxycytidine has been shown to inhibit the growth of certain strains of bacteria and can be used for the treatment of tuberculosis. This drug also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis. !-- END OF PRODUCT DESCRIPTIONS --></p>Formule :C23H21N3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :435.44 g/mol7-Deaza-2'-deoxyadenosine
CAS :<p>7-Deaza-2'-deoxyadenosine is an oligodeoxynucleotide analog that has been shown to be a potent inhibitor of human ovarian carcinoma cells. It inhibits the uptake of organic anion transporters, which are proteins found in the cell membrane that transport organic anions such as nucleosides and nucleotides. 7-Deaza-2'-deoxyadenosine has also been shown to inhibit DNA synthesis and polymerase chain reactions by binding to the enzyme RNA polymerase II. This drug can be synthesized with solid phase chemistry, making it a highly reproducible product.</p>Formule :C11H14N4O3Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :250.26 g/molNicotinic acid riboside
CAS :<p>Nicotinic acid riboside is a nicotinic acid derivative that has been shown to increase NAD+ levels in cells. Nicotinic acid riboside has been shown to increase the activity of enzymes involved in energy metabolism and transfer reactions, as well as target enzymes such as nicotinamide phosphoribosyltransferase (NAMPT) and its substrate, nicotinamide mononucleotide (NMN). It also increases cellular NAD+ levels by inhibiting the degradative enzyme, nicotinamide phosphoribosyltransferase (NAMPT). Nicotinic acid riboside can be used to treat metabolic disorders such as diabetes mellitus type 2.</p>Formule :C11H13NO6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :255.22 g/mol
