Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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N4-Acetyl-5'-O-DMT-2'-O-methylcytidine
CAS :<p>N4-Acetyl-5'-O-DMT-2'-O-methylcytidine is a cytidine analogue that has been synthesized to be used as an enzyme-linked probe. It is labelled with biotin and can be detected by binding to an antibody which has been labelled with a fluorescent tag. Cytidine analogues are synthesized on a solid phase and then cleaved from the support material. The spacer arm is added to the 5' end of the nucleotide and the 3'-OH group is modified with 2'-O-methyl groups. N4-Acetyl-5'-O-DMT-2'-O-methylcytidine has been shown to be sensitive in techniques such as solid phase synthesis, nucleic acid research, and immunoassays.</p>Formule :C33H35N3O8Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :601.65 g/mol5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose
CAS :<p>Acadesine is a purine nucleoside analogue that inhibits the synthesis of ATP in cells. Acadesine blocks phosphorylation of adenosine monophosphate (AMP) to adenosine triphosphate (ATP) by inhibiting the activity of kinase-3, an enzyme involved in the production of ATP. Acadesine also inhibits the release of ATP from muscle cells into the blood stream and preferentially targets kidney cells, thereby reducing renal injury. Acadesine has been shown to be effective at reducing proteinuria and improving renal function in rats with acute kidney injury. Acadesine also has anti-inflammatory properties due to its ability to inhibit proteins that are involved in inflammation.</p>Formule :C9H14N4O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :258.23 g/mol2'-Deoxy-5-fluorouridine
CAS :<p>2'-Deoxy-5-fluorouridine is a nucleoside analog that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA. It has been shown to inhibit the growth of cancer cells and induce apoptosis in vivo. 2'-Deoxy-5-fluorouridine has also been shown to inhibit tumor growth in animal models by inhibiting the production of reactive oxygen species and upregulating tumor suppressor genes, such as p53. This drug also has inhibitory effects on enzymes that are involved in cell proliferation, such as protein kinase C and tyrosine kinases. 2'-Deoxy-5-fluorouridine is metabolized by water vapor, so it must be administered with a humidifier or nebulizer. 2'-Deoxy-5-fluorouridine may cause side effects such as nausea, vomiting, and diarrhea.</p>Formule :C9H11FN2O5Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :246.2 g/mol5-Methylcytidine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS :<p>5-Methylcytidine-5'-triphosphate sodium salt is a nucleoside diphosphate that is used as an activator in the synthesis of DNA. It is also used as a building block in the synthesis of anticancer agents, such as 5-methylcytosine monophosphate and phosphoramidites. The chemical name for this product is 5-methylcytidine-5'-triphosphate sodium salt and its CAS number is 327174-86-7. This product is available for purchase at Sigma Aldrich with a purity of 99%.</p>Formule :C10H18N3O14P3·xNaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :497.18 g/molAdenosine 5'-diphosphate monosodium salt
CAS :<p>Used for energy storage and in nucleic acid metabolism</p>Formule :C10H14N5NaO10P2Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :449.18 g/molAbacavir
CAS :<p>Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase (RT) inhibitor with anti-retroviral activity against HIV. Good oral bioavailability, high aqueous solubility and good cerebrospinal fluid penetrance. Synergistic with other nucleoside RT inhibitors such as AZT.</p>Formule :C14H18N6ODegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :286.33 g/mol2-Amino-2'-deoxyadenosine
CAS :<p>2-Amino-2'-deoxyadenosine is a modified nucleoside, closely related to adenosine in which the 2'-hydroxyl group is replaced by an amino group. This compound has potential research applications</p>Formule :C10H14N6O3Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :266.26 g/molAdenylyl-3'-5'-cytidine
CAS :<p>Adenylyl-3'-5'-cytidine (3'-5'-CYT) is a postulated naturally occurring dinucleoside that has been shown to be involved in many metabolic processes. It has been found to interact with serum albumin, which may be related to the molecule's ability to bind with the ligand and form a complex. 3'-5'CYT can be synthesized from cytidine using an enzyme called adenosine deaminase. This process is known as deamination. The product of this reaction can either be uracil or thymine, depending on the enzyme used. 3'-5'CYT is also a component of recombinant human polypeptides that have been shown to have anti-cancer properties.</p>Formule :C19H25N8O11PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :572.42 g/molRibavirin 5'-triphosphate tetrasodium salt - 10mM aqueous solution
CAS :<p>Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.</p>Formule :C8H15N4O14P3·Na4Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :576.1 g/molp-Coumaryl-coenzyme A
CAS :<p>Please enquire for more information about p-Coumaryl-coenzyme A including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C30H42N7O18P3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :913.68 g/mol5'-Azido-5'-deoxyguanosine
CAS :<p>5'-Azido-5'-deoxyguanosine is an analog of guanosine that can be synthesized in a solid-phase reaction. It can also be enzymatically generated from 5'-azido-5'-deoxyadenosine. This molecule is reactive and has been shown to be an effective inhibitor of DNA synthesis in vivo assays. The use of 5'-azido-5'-deoxyguanosine has been explored as a potential treatment for leishmaniasis, a disease caused by the protozoan parasite Leishmania donovani.</p>Formule :C10H12N8O4Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :308.25 g/molN4-Benzoyl-5'-O-DMT-cytidine
CAS :<p>N4-Benzoyl-5'-O-DMT-cytidine is a novel modified nucleoside that can be phosphorylated by T4 kinase to form 5'-O-DMT-N4-benzoyl cytidine, which is an antiviral agent. This active compound is also an activator of DNA polymerases and has anticancer properties. N4-Benzoyl-5'-O-DMT cytidine has been shown to inhibit the replication of HIV in human cells and inhibit tumor growth in animal models. It has been synthesized with high quality and high purity, and has been assigned CAS No. 81246-76-6.</p>Formule :C37H35N3O8Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :649.69 g/molAlloxan hydrate
CAS :<p>A pyrimidine derivative, widely used for the induction of diabetes in experimental animals. It preferentially accumulates in pancreatic β cells in Langerhans islets via glucose transporter GLUT2. In the presence of intracellular thiols such as glutathione, it gets involved in a cyclic redox reaction with its reduction product, dialuric acid. This triggers the production of toxic levels of reactive oxygen species (ROS) and directs the cells in necrosis. Alloxan also inhibits glucokinase, which regulates glucose-induced insulin secretion.</p>Formule :C4H2N2O4•xH2ODegré de pureté :Min. 95%Masse moléculaire :142.07 g/mol5-Carboxy-2'-deoxyuridine
CAS :<p>5-Carboxy-2'-deoxyuridine is a nucleoside analogue that inhibits herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) replication. It is used to treat genital herpes infections caused by HSV-1 or HSV-2. 5-Carboxy-2'-deoxyuridine has been shown to inhibit the growth of human cancer cells in culture, and is currently being investigated as a potential anticancer drug. This drug binds with high affinity to the viral DNA polymerase, forming a covalent bond with the uracil base in the viral DNA chain. This prevents further elongation of the chain, inhibiting viral replication. 5-Carboxy-2'-deoxyuridine also inhibits cellular protein synthesis and cell division, which may be due to its ability to bind with aldehyde groups on surfactant proteins.END></p>Formule :C10H12N2O7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :272.21 g/molAdenosine-5'-O-(1-thiotriphosphate) lithium salt - 100 mM aqueous solution
CAS :<p>Adenosine-5'-O-(1-thiotriphosphate) lithium salt is an inhibitor of the guanine nucleotide-binding protein that is reversibly inhibited by adenosine triphosphate. It has been shown to inhibit HIV infection by binding to the Ryanodine receptor and blocking the release of calcium ions from intracellular stores. This prevents the activation of caspases, which are enzymes that cause cell lysis. Adenosine-5'-O-(1-thiotriphosphate) lithium salt also blocks transcription and polymerase chain reactions, and may inhibit the growth of cancer cells by inhibiting epidermal growth factor receptors on the cell surface.</p>Formule :C10H12Li4N5O12P3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :546.98 g/molN6-Benzyl-2-deoxyadenosine
<p>N6-Benzyl-2-deoxyadenosine is a modified nucleotide that can be incorporated into DNA during replication. The compound has antiviral properties and can act as an activator for the transcription of genes involved in the immune response. It is synthesized by coupling two phosphate groups to adenosine monophosphate, which is then modified with a benzyl group. This modification prevents N6-benzyl-2-deoxyadenosine from being phosphorylated and degraded to adenosine monophosphate, resulting in a stable molecule that can be incorporated into DNA.</p>Formule :C17H19N5O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :341.36 g/mol9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)adenine
CAS :<p>9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine (9dFdA) is a potent inhibitor of the enzyme s-adenosylhomocysteine hydrolase, which is involved in the synthesis of adenosine. 9dFdA inhibits the growth of Trichomonas vaginalis and has shown good activity against other pathogens, such as Staphylococcus aureus and Mycobacterium tuberculosis. It also has been shown to have potent inhibitory activity against adenosine deaminase, which prevents an immune response by preventing cells from producing the amino acid adenosine. This compound also inhibits uridine phosphorylase, which is involved in nucleotide biosynthesis.</p>Formule :C10H12FN5O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :269.24 g/mol3'-Amino-2',3'-dideoxycytidine
CAS :<p>3'-Amino-2',3'-dideoxycytidine's lack of a 3'-hydroxyl group makes it a chain terminator for DNA polymerase, a key application in Sanger sequencing. Additionally, the 3'-amino group serves as a functional handle for modifying the 3' end of oligonucleotides with various labels or conjugates, expanding their utility in research and diagnostics.</p>Formule :C9H14N4O3Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :226.23 g/mol2'-Deoxyadenosine-5'-diphosphate sodium salt
CAS :<p>2'-Deoxyadenosine-5'-diphosphate sodium salt is a nucleotide that is involved in the synthesis of DNA. It is a structural analog of adenosine-5'-diphosphate and can be used as an experimental tool to study metabolic disorders. 2'-Deoxyadenosine-5'-diphosphate sodium salt binds to p2y receptors and blocks their activation, which inhibits cellular energy metabolism. This compound is structurally similar to adenosine-5'-triphosphate, but has been shown to inhibit the expansion of cells when heated, unlike adenosine-5'-triphosphate. 2'-Deoxyadenosine-5'-diphosphate sodium salt also inhibits cell proliferation in cancer cells and may have potential as a therapeutic agent for bowel disease.</p>Formule :C10H12N5O9P2·xNaDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :408.18 g/molN4-Acetyl-2'-O-methylcytidine
CAS :<p>N4-Acetyl-2'-O-methylcytidine is a chemical compound that is an analog of cytidine. It has been shown to have the ability to stabilize RNA molecules at high temperatures and has been used in the study of epigenetics and thermophilic organisms. N4-Acetyl-2'-O-methylcytidine is also known as AEMC. This compound can be used for reversed phase high performance liquid chromatography, which separates compounds based on their size and shape. Furiosus is a strain of bacteria that contains this chemical compound in its genome. Furiosus was found to contain this compound in its DNA by using posttranscriptional modification techniques such as high performance liquid chromatography (HPLC) and proton nuclear magnetic resonance (NMR).</p>Formule :C12H17N3O6Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :299.29 g/mol
