Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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Cytidine 5'-diphosphocholine
CAS :<p>Cytidine 5'-diphosphocholine is a nucleotide that is a precursor of uridine 5'-triphosphate and cytidine 5'-monophosphate, which are important for DNA synthesis. Cytidine 5'-diphosphocholine is used in the preparation of samples for experiments. This compound has been shown to induce neuronal death in an experimental model. It has also been shown to inhibit polymerase chain reactions and affect the activity of enzymes such as alpha-7 nicotinic acetylcholine receptors and glutamate decarboxylase. Cytidine 5'-diphosphocholine has been found to have no effect on basic fibroblast cells, but it does have physiological effects on human erythrocytes.</p>Formule :C14H26N4O11P2Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :488.32 g/mol7-Methyl-6-thioguanosine inner salt
CAS :<p>7-Methyl-6-thioguanosine inner salt is a compound that inhibits the activity of creatine kinase and phosphatase, which are enzymes involved in energy metabolism. It also binds to actin filaments and prevents their depolymerization. The binding mechanism of 7-methyl-6-thioguanosine inner salt is believed to be due to its ability to form disulfide bonds with cysteine residues on the surface of the enzyme. This inhibition has been shown to reduce the ATP production in mammalian cells and has been used as a model system for studying cellular processes.</p>Formule :C11H15N5O4SDegré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :313.33 g/molCytidine 5'-triphosphate disodium dihydrate
CAS :<p>Cytidine 5'-triphosphate (CTP) disodium dihydrate prevents the action of aspartate carbamoyltransferase, an enzyme involved in pyrimidine biosynthesis. CTP serves as a molecule of high energy and acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.</p>Formule :C9H16N3O14P3•(H2O)2•Na2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :565.17 g/mol2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl-guanosine
CAS :<p>2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl-guanosine is a synthetic nucleoside that has been modified with a tert-butyldimethylsilyl group. This modification is used to improve the efficiency of coupling reactions between nucleosides and phosphoramidites in oligonucleotide synthesis. The 2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl guanosine is also used as a chromophore in spectroscopy experiments and as a ligand in metal coordination chemistry.</p>Formule :C41H51N5O8SiDegré de pureté :Min. 98 Area-%Couleur et forme :Off-White PowderMasse moléculaire :769.96 g/molN4-Etheno 2'-deoxycytidine
CAS :<p>N4-Etheno 2'-deoxycytidine is an aromatic hydrocarbon that has been shown to be a potent inhibitor of DNA synthesis. It binds covalently with the N4 position of deoxycytidine in DNA, thereby inhibiting transcription and replication. This drug has been shown to be a potent inhibitor of DNA synthesis in human cells when it is added to the culture medium, but it does not inhibit protein synthesis. N4-Etheno 2'-deoxycytidine can also react with hydrogen bonds in cellular proteins and nucleosides that are involved in DNA repair mechanisms. This drug is reactive and may cause oxidative damage to cellular components, which may lead to carcinogenesis.</p>Formule :C11H13N3O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :251.24 g/molNicotinic acid adenine dinucleotide sodium
CAS :<p>Nicotinic acid adenine dinucleotide sodium (NAAD) is a novel anticancer and antiviral agent. NAAD is an analog of nicotinamide adenine dinucleotide (NAD) that has been modified to include a sodium ion. This modification inhibits the synthesis of DNA and RNA, which are required for cell division and replication. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. In addition, NAAD suppresses viral replication by inhibiting protein synthesis in cells infected with HIV-1 or influenza virus. NAAD has also been shown to be a potent inhibitor of ribonucleoside reductase, which converts ribonucleosides into deoxyribonucleosides. This inhibition prevents the conversion of diphosphate nucleotides into monophosphate nucleotides, which are necessary for DNA synthesis.</p>Formule :C21H26N6O15P2•NaDegré de pureté :Min. 95%Masse moléculaire :687.4 g/molCyclic inosine diphosphate ribose
CAS :<p>Cyclic inosine diphosphate ribose is a synthetic, fluorescent compound that can be used as a probe for assays. It has been synthesized by the solid-phase synthesis of a specific antibody and is bioconjugated with an oligo(ethylene glycol) moiety. Cyclic inosine diphosphate ribose can be used to measure lymphocyte activation, which is important for the study of autoimmune diseases and cancer. Cyclic inosine diphosphate ribose has also been shown to bind to the ryanodine receptor, which causes an increase in intracellular calcium concentration.</p>Formule :C15H20N4O14P2Degré de pureté :Min. 95%Masse moléculaire :542.29 g/molN6-Hydroxymethyladenosine
CAS :<p>Please enquire for more information about N6-Hydroxymethyladenosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C11H15N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :297.27 g/mol2'-Phosphoadenosine 5'-phosphosulfate tetralithium salt (mixture with 3'-isomer)
CAS :<p>2'-Phosphoadenosine 5'-phosphosulfate tetralithium salt (mixture with 3'-isomer) is a novel, modified nucleoside. It has antiviral properties and can be used for the treatment of cancer. 2'-Phosphoadenosine 5'-phosphosulfate tetralithium salt (mixture with 3'-isomer) inhibits viral replication by inhibiting the synthesis of viral DNA and RNA. This compound also inhibits cancer cell proliferation by inhibiting deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) synthesis.</p>Formule :C10H11N5O13P2S·4LiDegré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :531 g/molPolyguanylic acid potassium
CAS :<p>Polyguanylic acid potassium salt is a guanosine analog that is used as a probe for studying the interaction of cellular and target tissue. It has been found to be taken up by cells, with high affinity constants, and to be immobilized on cell surfaces. Polyguanylic acid potassium salt can also be used as an anticancer agent against epidermoid carcinoma cells with high affinity constants. The compound interacts with DNA and inhibits the growth of the tumor cells by interfering with the uptake of nucleic acids.</p>Formule :(C10H14N5O8P)x•KxDegré de pureté :Min. 95%Couleur et forme :Powder(E)-2'-Deoxy-2'-(fluoromethylene)cytidine
CAS :<p>(E)-2'-Deoxy-2'-(fluoromethylene)cytidine is a cytostatic compound that inhibits DNA synthesis in tumor cells. It has been shown to be more potent than tezacitabine and hl-60 cells, as well as being less toxic than benzimidazole compounds. This analog of cytosine has been shown to have potent antitumor activity against carcinoma cell lines and myeloid leukemia cell lines. The oral prodrug form of this drug has been shown to be an effective treatment for myeloid leukemia in mice.</p>Formule :C10H12FN3O4Degré de pureté :Min. 95%Masse moléculaire :257.22 g/mol2-Methylthio-N6-methyladenosine
CAS :<p>2-Methylthio-N6-methyladenosine is an adenosine nucleoside that is found in the DNA of eukaryotes. It is similar to 2-methylthio-n6-isopentenyladenosine, which is a modified form of n6-methyladenosine. The chemical structures of both molecules are related to the thermodynamic properties of the molecule and their ability to be postsynthetically modified. These modifications can lead to changes in their translation, which can have implications for the development and progression of disease. 2-Methylthio-N6-methyladenosine has a role in epigenetics, which is defined as changes in gene expression without any alterations in DNA sequence. In this case, it may modify the chloride ion concentration by changing its chemical structure, leading to epigenetic changes that can affect how genes are expressed or translated into proteins.</p>Formule :C12H17N5O4SDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :327.36 g/mol2',3',5'-Triacetyl -azacytidine
CAS :<p>2',3',5'-Triacetyl-azacytidine is a transcription factor that has dose-dependent effects on the production of melanin. It inhibits the synthesis of melanin by binding to two specific transcription factors, the microphthalmia-associated transcription factor and the histone methyltransferases. This drug also inhibits tyrosinase, which is an enzyme involved in the production of melanin. 2',3',5'-Triacetyl-azacytidine has been shown to inhibit the growth of murine melanoma cells and may be useful for treating skin cancer.</p>Formule :C14H18N4O8Degré de pureté :Min. 95%Masse moléculaire :370.31 g/molγ-(2-Azidoethyl)-ATP sodium, 10 mM aqueous solution
<p>Please enquire for more information about γ-(2-Azidoethyl)-ATP sodium, 10 mM aqueous solution including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C12H19N8O13P3•NaxDegré de pureté :Min. 95%S-Adenosyl-L-methionine
CAS :<p>S-Adenosyl-L-methionine (SAM-e) is a co-substrate involved in methyl group transfer to nucleic acids, proteins and lipids. SAM-e is produced in the liver from adenosine triphosphate (ATP) and methionine by action of the enzyme methionine adenosyltransferase. Therapeutic use of S-adenosyl-L-methionine includes osteoarthritis, liver disease and major depressive disorder. S-Adenosyl-L-methionine is available as a dietary supplement.</p>Formule :C15H22N6O5SDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :398.44 g/mol5-Carboxymethylaminomethyl- 2'-O-methyluridine
CAS :<p>5-Carboxymethylaminomethyl- 2'-O-methyluridine (5CmAMU) is a modified nucleobase that is categorized as a modified base. It is an analog of uridine, which has been shown to be effective against tuberculosis in mice. 5CmAMU inhibits the methylation of rRNA and DNA by binding to the enzyme RNA methyltransferase, thereby inhibiting transcription and replication. This modification has also been shown to inhibit cellular proliferation and promote apoptosis. 5CmAMU binds to guanine with a stoichiometry of 1:1, which provides evidence for its role in DNA synthesis and repair. The structural modifications on this molecule may lead to diagnostic applications or treatments for diseases such as tuberculosis.</p>Formule :C13H19N3O8Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :345.31 g/molCytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide
CAS :<p>Cytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide is a novel cytidine phosphoramidate monophosphate that has been shown to have anticancer and antiviral properties. It can be used as a DNA nucleoside phosphoramidite in the synthesis of oligonucleotides or as an antiviral agent by inhibiting viral RNA replication. Cytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide is chemically synthesized in high purity and quality for use in research in the field of DNA, nucleosides, and antiviral agents.</p>Formule :C30H52N7O9PDegré de pureté :Min. 95%Masse moléculaire :685.75 g/mol5,6-Dihydrothymidine
CAS :<p>5,6-Dihydrothymidine is a hydroxylated thymidine analogue. It binds to the leukocyte antigen, which is found on many different types of cells. 5,6-Dihydrothymidine inhibits the replication of herpes simplex virus and can be used for diagnostic purposes. 5,6-Dihydrothymidine has been shown to have conformational properties that are similar to those of thymine, which allows it to bind to the template strand in DNA. This binding prevents the synthesis of messenger RNA from DNA. 5,6-Dihydrothymidine is also able to inhibit cell growth in culture and can be used as a cell culture medium supplement.</p>Formule :C10H16N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :244.24 g/mol8-(p-Chlorophenylthio)-cGMP
CAS :<p>8-(p-Chlorophenylthio)-cGMP is a modified nucleoside that has anticancer activity. It inhibits DNA synthesis and the activation of protein kinases, which are enzymes that transmit signals from the cell surface to the nucleus. 8-(p-Chlorophenylthio)-cGMP can also inhibit viral replication by inhibiting the production of new virus particles and by inhibiting the action of reverse transcriptase, an enzyme that converts RNA into DNA.</p>Formule :C16H15ClN5O7PSDegré de pureté :Min. 95%Masse moléculaire :487.81 g/mol2-Deoxycytidine 3',5'-diphosphate
CAS :<p>2-Deoxycytidine 3',5'-diphosphate is an additive that is used in the production of DNA. It is a single-stranded nucleotide with a guanine base. 2-Deoxycytidine 3',5'-diphosphate has been shown to inhibit bacterial growth by reacting with hydrogen peroxide, which is produced during the process of oxidative phosphorylation. This reaction leads to the formation of reactive oxygen species, which damage DNA and cause cell death. The compound also binds to metal ions and prevents them from interacting with cellular components. 2-Deoxycytidine 3',5'-diphosphate can be used as a chromatographic agent for separating DNA fragments according to their size.</p>Formule :C9H15N3O10P2Degré de pureté :Min. 95%Masse moléculaire :387.18 g/mol
