Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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9-Deazaguanosine
CAS :<p>9-Deazaguanosine is a naturally occurring purine, which has been shown to inhibit the binding of adenosine deaminase enzyme. This enzyme is responsible for the conversion of adenosine to inosine, and plays a role in the replication of viruses. 9-Deazaguanosine has also been shown to have an inhibitory effect on trichomonas vaginalis, benzyl groups, and anomers. The hydroxyl group on 9-Deazaguanosine interacts with mammalian cells which may be related to its inhibitory effect on leishmania and hepatitis.</p>Formule :C11H14N4O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :282.25 g/mol2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine
CAS :2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine is a modified nucleoside analog for research applicationsFormule :C14H18FN5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :355.33 g/molPalmitoyl coenzyme A potassium salt
CAS :Palmitoyl coenzyme A potassium salt is a novel, modified nucleoside that has antiviral and anticancer activities. It is a phosphoramidite with a phosphate group at one end and a palmitoyl group at the other. The phosphate group is attached to the 5' position of the sugar, while the palmitoyl group is attached to the 3' position of the sugar. Palmitoyl coenzyme A potassium salt can be used in DNA synthesis.Formule :C37H65N7O17P3SKDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :1,044.03 g/mol2'-O-(2-Methoxyethyl)-5-methyluridine
CAS :<p>2'-O-(2-Methoxyethyl)-5-methyluridine is a uridine nucleoside that has been prepared by the reaction of amidite with 5-methyluridine. 2'-O-(2-Methoxyethyl)-5-methyluridine is an important intermediate in the synthesis of oligonucleotides, which are synthesized from phosphoramidites. The phenyl group on the amido group is a reactive group that reacts with other functional groups to form an oligonucleotide. 2'-O-(2-Methoxyethyl)-5-methyluridine has a high yield and can be used as a reagent for organic chemistry.</p>Formule :C13H20N2O7Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :316.31 g/mol2,6-Dichloro-9-(β-D-ribofuranosyl)purine
CAS :<p>2,6-Dichloro-9-(β-D-ribofuranosyl)purine is a nucleoside analog composed of a modified purine base and a ribose sugar. It has possible applications as an intermediate in nucleoside chemistry, particularly for the synthesis of functionalized purine nucleosides used in biological and pharmaceutical research.</p>Formule :C10H10Cl2N4O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :321.12 g/mol8-Aza-6-hydroxy-2-mercaptopurine
CAS :<p>8-Aza-6-hydroxy-2-mercaptopurine (8AzaMP) is a novel nucleoside analog that is an activator of the thymidylate synthase enzyme. It has been shown to inhibit the replication of many DNA viruses and to inhibit tumor growth in animal models. 8AZA MP has been evaluated in Phase I and II clinical trials for the treatment of various cancers, including malignant melanoma, renal cell carcinoma, and chronic lymphocytic leukemia. This drug has also shown promise as a chemotherapeutic agent for AIDS patients with HIV infection or AIDS-related complex.</p>Formule :C4H3N5OSDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :169.17 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine
CAS :<p>N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine is a cytosine analog with high affinity for the T cell receptor. It can be used to generate antibodies against cytosine and as a screening tool for plasmon resonance.</p>Formule :C32H32FN3O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :589.61 g/molCytidine 5'-monophosphate disodium salt
CAS :Cytidine 5'-monophosphate disodium salt (CMPDS) is a prodrug that is converted to cytidine 5'-monophosphate, an active form, in the acidic environment of cancer cells. CMPDS has been shown to inhibit the growth of squamous carcinoma and other solid tumours by binding to survivin, which regulates cell growth and apoptosis. CMPDS also inhibits the activity of matrix metalloproteinases-9 (MMP-9), an enzyme that promotes tumor growth by breaking down connective tissue. This drug can be used as a therapeutic agent for treatment of congestive heart failure due to its ability to increase mitochondrial membrane potential and decrease myocardial infarct size.Formule :C9H12N3Na2O8PDegré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :367.16 g/molGuanosine 5'-O-(2-thiodiphosphate) trilithium salt
CAS :Guanosine 5'-O-(2-thiodiphosphate) trilithium salt (GTPTS) is a membrane-permeable molecule that hyperpolarizes cells by inhibiting the movement of ions through the cell membrane. GTPTS is activated by extracellular calcium and potassium ions, which are involved in signal transduction pathways. It has been shown to inhibit the release of neurotransmitters, such as acetylcholine, dopamine, serotonin, and norepinephrine. GTPTS also blocks voltage-gated sodium channels, which leads to a reduction in neuronal excitability. The drug has been shown to have analgesic effects in animal models of pain and can be used to treat chronic pain due to nerve damage.Formule :C10H12Li3N5O10P2SDegré de pureté :Min. 85 Area-%Couleur et forme :PowderMasse moléculaire :477.06 g/mol5-Methoxycarbonylmethyl-2-thiouridine
CAS :<p>Nucleoside functionalised on the base</p>Formule :C12H16N2O7SDegré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :332.33 g/mol8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt
CAS :<p>8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt (8-CPT-cAMP) is a cyclic nucleotide that activates adenyl cyclase, which increases intracellular levels of the second messenger cAMP. It also inhibits P2Y receptors and other ion channels. 8-CPT-cAMP has been shown to be effective in activating cells expressing the enzyme camp levels, such as those found in heart muscle cells. This drug is used clinically to lower blood pressure, as it has been shown to activate amp-activated protein kinase and calcium chelator. 8-CPT-cAMP may have clinical applications for the treatment of cancer due to its ability to induce cell cycle arrest and apoptosis.</p>Formule :C17H16ClN5O6PS·NaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :507.82 g/mol(R)-N-(2,3-Dihydro-1H-indenyl)adenosine
CAS :<p>(R)-N-(2,3-Dihydro-1H-indenyl)adenosine is a purine nucleoside with the attachment of a 2,3-dihydro-1H-indenyl group via a nitrogen atom. This adenosine-based product can be used for research purposes</p>Formule :C19H21N5O4Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :383.4 g/mol5-(Cyanomethyl)-uridine
CAS :<p>5-(Cyanomethyl)-uridine (5-CMU) is a monophosphate nucleoside that is synthetically derived from uracil. This nucleoside has antiviral activity and can be used to treat infections caused by the herpesviridae family, such as herpes simplex virus type 1 and 2. 5-CMU is modified with cyanomethyl groups on the ribose moiety. It is also a phosphoramidite building block for DNA synthesis and can be used in the preparation of oligonucleotides. The CAS number for 5-CMU is 58479-73-5.</p>Formule :C11H13N3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :283.24 g/mol5-Fluorocytosine
CAS :Flucytosine is an antifungal agent that inhibits the synthesis of DNA by preventing the conversion of deoxyuridine monophosphate to uracil monophosphate. It is used as an antiretroviral therapy in combination with other drugs, such as zidovudine and dideoxyinosine, to treat HIV infections. Flucytosine has been shown to have a strong antitumor response in a model system involving mice with sarcoma 180. This drug can cause serious side effects, including drug interactions and resistance mutations in microorganisms. These side effects are often observed in patients undergoing cancer chemotherapy or immunosuppressive therapy.Formule :C4H4FN3ODegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :129.09 g/mol3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine
<p>3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is a nucleoside analog and activator that inhibits the replication of DNA. It is a novel antiviral drug that has antiproliferative properties and may be useful in the treatment of cancer. 3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is synthesized by reacting an activated phosphoramidite with 2',3'-dideoxyadenosine monophosphate to produce 3',5' dideoxythymidine 5'-monophosphate, which is then converted to 3',5' dideoxyuridine 5'-monophosphate. The last step involves the conversion of 3',5' dideoxyuridine 5'-monophosphate to 3' azidouridine 5'-monoph</p>Formule :C38H34N8O5Degré de pureté :Min. 95%Masse moléculaire :682.73 g/mol7-Deaza-2'-deoxy-6-methoxyguanosine
CAS :<p>7-Deaza-2'-deoxy-6-methoxyguanosine is a modified nucleoside and antiviral agent. It has been shown to inhibit the synthesis of DNA, RNA and protein in cells infected with the herpes simplex virus (HSV). 7-Deaza-2'-deoxy-6-methoxyguanosine is also an anticancer agent that has been shown to inhibit tumor growth in animal models. This compound is synthesized by phosphoramidite chemistry and is a novel precursor for the preparation of modified DNA and RNA. The purity of this product is greater than 98%.</p>Formule :C12H16N4O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :280.29 g/mol2',3',5'-Tri-O-acetyl-6-azauridine
CAS :<p>2',3',5'-Tri-O-acetyl-6-azauridine is a nucleoside analog for research purposes. The replacement of a carbon atom with a nitrogen atom on the uracil base affects how the molecule interacts with cellular processes. It has the potential to interfere with normal metabolic processes within cells, particularly those related to RNA synthesis. Due to its ability to disrupt cell growth, it could be studied for any potential antiviral or antitumor properties.</p>Formule :C14H17N3O9Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :371.3 g/mol3,5-Dichloro-4-pyridone-1-acetic acid
CAS :3,5-Dichloro-4-pyridone-1-acetic acid is a chlorinated derivative of 7-aminocephalosporanic acid that is synthesized from hydrochloric acid and chloroacetic anhydride. It is used in the pharmaceutical industry as a reagent to produce medicines such as antibiotics and anti-inflammatory agents. The product yield of this reaction is high, which makes it an excellent choice for industrial use. 3,5-Dichloro-4-pyridone-1-acetic acid also has a low toxicity profile and can be easily degraded by bacteria in the environment.Formule :C7H5Cl2NO3Degré de pureté :Min. 95%Masse moléculaire :222.02 g/mol3',5'-Di-O-acetylthymidine
CAS :3',5'-Di-O-acetylthymidine is a pyrimidine nucleoside that has antibacterial activity. It is an anomer of thymidine, which makes it a hydroxymethylated analog of thymine. It can be used in the preparation of uridine for the treatment of human immunodeficiency virus type 1 (HIV-1) infection and to study the mechanism of action of this nucleoside on HIV-1 replication. 3',5'-Di-O-acetylthymidine binds to the ribose moiety of pyrimidines and inhibits bacterial growth by inhibiting DNA synthesis. This compound also inhibits the growth of staphylococcus that are resistant to penicillin. The chemical structure of 3',5'-Di-O-acetylthymidine can be modified with different acetic acid substituents to produce other pyrimidine nucleosides with different antibacterial properties, such as 4-Formule :C14H18N2O7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :326.3 g/molN4-Benzoyl-5'-O-DMT-5-methylcytidine
CAS :N4-Benzoyl-5'-O-DMT-5-methylcytidine is a deoxyribonucleoside that has been modified to make it resistant to nucleases. N4-Benzoyl-5'-O-DMT-5-methylcytidine is an antiviral agent, which inhibits the synthesis of viral DNA by inhibiting the activity of viral DNA polymerase. It also acts as an activator for cellular DNA polymerases and phosphoramidites. The drug can be used in the treatment of HIV and other retroviruses, herpes viruses, and certain types of cancer.Formule :C38H37N3O8Degré de pureté :Min. 95%Couleur et forme :White SolidMasse moléculaire :663.73 g/mol
