Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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5-O-[[[(1S)-1-Methyl-2-(1-methylethoxy)-2-oxoethyl]amino]-phenoxyphosphinyl]-cytidine
CAS :5-O-[[[(1S)-1-Methyl-2-(1-methylethoxy)-2-oxoethyl]amino]-phenoxyphosphinyl]-cytidine is a modified nucleoside analog that inhibits the synthesis of DNA and RNA. It has been shown to have antiviral, anticancer, and antiinflammatory activities. 5-O-[[[(1S)-1-Methyl-2-(1-methylethoxy)-2-oxoethyl]amino]-phenoxyphosphinyl]-cytidine is a ribonucleoside that can be used as a building block for the production of deoxyribonucleosides (i.e., as an activator). This product also has high purity and quality, as well as being novel in structure.Formule :C21H29N4O9PDegré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :512.45 g/molN2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2-aminopurine
N2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2-aminopurine is a nucleoside that is modified with a chlorine group. The modification of the nucleoside may enhance its anticancer activity. N2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2 aminopurine has been shown to inhibit the growth of virus and cancer cells by inhibiting DNA synthesis. It has also been shown to induce apoptosis in human leukemia cells.Formule :C21H30ClN5O9Degré de pureté :Min. 95%Couleur et forme :White to beige solid.Masse moléculaire :531.94 g/molCytidine-2'-monophosphate sodium
CAS :Cytidine-2'-monophosphate sodium (CMP) is a nucleotide that is used as a monophosphate or diphosphate. It can be used to synthesize DNA and RNA. CMP also has antiviral, anticancer, and high purity properties. CMP is an activator of DNA polymerases and helps in the synthesis of DNA. It has novel properties that make it different from other nucleotides, such as its modified sugar moiety.
Formule :C9H12Na2N3O8PDegré de pureté :Min. 90%Couleur et forme :PowderMasse moléculaire :367.18 g/mol5'-O-DMT-2'-O-methyl-N6-phenylacetyladenosine
5'-O-DMT-2'-O-methyl-N6-phenylacetyladenosine is a synthetic nucleoside with anticancer properties. It is modified to be more resistant to phosphodiesterase which blocks the synthesis of DNA and RNA. This drug has been shown to activate the immune system, inhibit tumor growth, and inhibit viral replication. It has been shown to be effective in animal models against leukemia and lymphoma. The high quality pure chemical will be used for use in research purposes only.Degré de pureté :Min. 95%6-O-Methylinosine
CAS :6-O-Methylinosine is a modified nucleoside that is used in the synthesis of recombinant proteins. It is synthesized from the reaction of methylphosphate and 6-O-methylguanosine. The phosphate group of the 6-O-methylguanosine molecule reacts with methylphosphate in an acid or neutral environment, while it reacts with phosphoric acid in a basic environment. This reaction can be monitored by measuring the amount of free phosphate groups present after the reaction. The rate of this reaction can be increased by increasing temperature and pH. 6-O-Methylinosine has been shown to have anticancer activity, which may be due to its ability to inhibit enzyme catalysis and modify DNA structure.Formule :C11H14N4O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :282.25 g/mol7-Deaza-2'-deoxyguanosine
CAS :7-Deaza-2'-deoxyguanosine is an analog of guanosine that has been shown to inhibit the activity of telomerase. This enzyme synthesizes a sequence of DNA called a telomere, which protects the ends of chromosomes from deterioration and prevents chromosomal end-to-end fusion. 7-Deaza-2'-deoxyguanosine has an inhibitory effect on the polymerase chain reaction (PCR) in mammalian cells and inhibits the transcription-polymerase chain reaction (PCR) in vitro. It has also been shown to be potent against cancer cells. 7-Deaza-2'-deoxyguanosine is synthesized by solid phase synthesis, which is a chemical process that involves attaching one molecule to another molecule with similar structure, using organic solvents as intermediates.Formule :C11H14N4O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :266.26 g/mol2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine
CAS :2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is a purine nucleoside where the purine base has a 2-amino group at position 2 and a chlorine at position 6. The sugar is 2'-deoxy, meaning it is like the sugar found in DNA, lacking the 2'-hydroxyl group that is present in RNA. The amino and chloro groups on the purine base modify how this molecule behaves in biological systems making it useful in research applications.Formule :C10H12ClN5O3Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :285.69 g/mol5-Methyluridine
CAS :5-Methyluridine is a nucleoside that is used to inhibit the replication of cells. It is also used for the treatment of cancer, infectious diseases, and other conditions. 5-Methyluridine inhibits cellular replication by binding to ribothymidine and uridine in the nucleus. The inhibition of cellular proliferation is due to a lack of dna synthesis and RNA synthesis. This nucleoside has been shown to have inhibitory properties against mouse tumor cells grown in vitro, as well as the wild-type strain grown in vivo. 5-Methyluridine may be useful for the treatment of cancer tissues because it can suppress the growth of tumors by inhibiting their ability to replicate.Formule :C10H14N2O6Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :258.23 g/molTrifluorothymidine
CAS :Treats herpes-associated keratitis and keratoconjunctivitis; antineoplastic
Formule :C10H11F3N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :296.2 g/molCytidine-5'-diphosphate trisodium
CAS :Cytidine-5'-diphosphate trisodium (CDP-Tris) is a copolymerization agent that contains a formamide molecule, which is used to increase the viscosity of the polymer. It is also used as a hydrogen bond donor and acceptor in the synthesis of polymers. CDP-Tris can be used for DNA replication and repairs damaged DNA by binding to 7-methylguanine, one of the most common lesions found in DNA. This agent has been shown to be effective in diluting crude cell extracts from E. coli bacteria. CDP-Tris is also used to synthesize polymers with 3-methylcytidine monomers that contain nitrogen atoms. These polymers are then used as substitutes for natural polymers such as cellulose and starch, which can be difficult to process because they are hydrophobic.Formule :C9H12N3Na3O11P2Degré de pureté :Min. 95 Area-%Couleur et forme :White Yellow PowderMasse moléculaire :469.12 g/mol2',3'-Di-O-acetyl-D-uridine
CAS :2',3'-Di-O-acetyl-D-uridine is a nucleoside for use in research applicationsFormule :C13H16N2O8Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :328.27 g/mol2'-Deoxy-6-methylthioguanosine
CAS :2'-Deoxy-6-methylthioguanosine is a novel nucleoside and nucleotide analog with antiviral and anticancer activities. It has been shown to inhibit the replication of DNA by inhibiting the activity of DNA polymerase. The target of this drug is not related to any virus or bacterial species, but it inhibits the growth of cancer cells in vitro. The synthesis of 2'-deoxy-6-methylthioguanosine can be achieved by modifying commercially available phosphoramidites.Formule :C11H15N5O3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :297.33 g/mol2'-O-Benzoyl-5'-O-DMT-4-thiouridine
2'-O-Benzoyl-5'-O-DMT-4-thiouridine is a phosphoramidite monophosphate nucleoside analog. It has antiviral and anticancer properties, and has been shown to activate the immune system in mice. 2'-O-Benzoyl-5'-O-DMT-4-thiouridine is also novel because it is structurally different from all other nucleosides that have been studied for antiviral and anticancer activity. This drug can be used as an activator of DNA synthesis in vitro.Formule :C37H34N2O8SDegré de pureté :Min. 95%Couleur et forme :Yellow SolidMasse moléculaire :666.76 g/mol3',5'-O-(1,1,3,3-Tetraisopropyldisiloxane-1,3-diyl)-2'-ketouridine
CAS :Used as a protected 2'-ketouridine nucleoside in the synthesis of modified RNA oligonucleotides. The 1,1,3,3-tetraisopropyldisiloxane-1,3-diyl (TIPDS or TBDPSi2) group protects the 3' and 5' hydroxyl groups, while the 2'-keto (or 2'-oxo) modification introduces a specific functional group at the 2' position of the ribose sugar.Formule :C21H36N2O7Si2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :484.69 g/mol2'-O-Methyladenosine
CAS :2'-O-Methyladenosine (2'-OMeA) is a nucleoside that is a low-energy analog of adenosine. It has been shown to be an effective inhibitor of protein synthesis in vitro, by inhibiting RNA polymerase in the process of transcription. 2'-OMeA has also been shown to inhibit virus replication in vitro and to have potent inhibitory activity against human immunodeficiency virus type 1 (HIV-1). 2'-OMeA inhibits viral replication by binding to the viral ribonucleotide reductase enzyme and blocking the conversion of ribonucleotides into deoxyribonucleotides. The chemical structures of 2'-OMeA are similar to those found in fatty acids and can be detected using chemical ionization mass spectroscopy. The sequence for 2'-OMeA was determined through sequencing methods including NMR spectroscopy and nuclear magnetic resonance data analysis.Formule :C11H15N5O4Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :281.27 g/mol5-Fluorouridine-5'-triphosphate triethylammonium salt - aqueous solution
5-Fluorouridine-5'-triphosphate triethylammonium salt - aqueous solution is an activated nucleoside that is synthesized from the triethylamine salt of 5-fluorouridine. This product has antiviral and anticancer activities, and can be used as a DNA-synthesizing agent in the synthesis of deoxyribonucleosides. It has been shown to inhibit replication of human immunodeficiency virus (HIV) by inhibiting viral reverse transcriptase, as well as cytomegalovirus (CMV) by inhibiting viral DNA polymerase.
Formule :C33H74N6O15P3FDegré de pureté :Min. 95%Couleur et forme :Colorless PowderMasse moléculaire :906.89 g/mol2'-Deoxy-a-cytidine
CAS :2'-Deoxy-a-cytidine is a nucleoside analog that inhibits the growth of bacteria by competitively binding to the 5' position of the ribose sugar in RNA. This prevents the enzyme from adding a new linkage to the ribose, which results in an irreversible blockage of RNA synthesis. 2'-Deoxy-a-cytidine has been shown to be bacteriostatic against Escherichia coli and other bacterial species. It is also able to inhibit adenosine production, although it does not show any activity against DNA synthesis.
2'-Deoxy-a-cytidine has been shown to be effective against E. coli and other bacterial species, but does not show any activity against DNA synthesisFormule :C9H13N3O4Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :227.22 g/molInosine 5'-diphosphate disodium salt
CAS :Inosine-5'-diphosphate disodium salt (IDPS) is a nitro compound that is used in the synthesis of antibacterial drugs. It is also used in the production of polymers and as a precursor to other organic compounds. IDPS has been shown to have antibacterial activity against halogeno bacteria, such as buprestidae, and many Gram-positive bacteria, including encapsulated strains. IDPS has been shown to be effective against both damaged cells and healthy cells in culture. The mechanism of action may involve inhibition of protein synthesis by blocking the ribosomes or by interfering with DNA replication. This drug also inhibits growth rate of japonica rice and heterocycles.Formule :C10H12N4Na2O11P2Degré de pureté :Min. 90.0 Area-%Couleur et forme :White PowderMasse moléculaire :472.15 g/molBucladesine calcium salt
CAS :Protein kinase A inhibitor; cAMP agonistFormule :C18H24N5O8PCaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :489.42 g/mol5-Hydroxymethylcytidine
CAS :5-Hydroxymethylcytidine is a nucleoside that has been shown to inhibit the activity of RNA polymerase by forming hydrogen bonds with the enzyme. It is used in vitro to study the role of messenger RNA in regulating gene expression, and also as a probe for transcriptase activity. 5-Hydroxymethylcytidine has also been shown to have a biological function in solid tumours and may be an analytical method for detecting cancer.Formule :C10H15N3O6Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :273.24 g/mol
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