Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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N-Pyrrolo-2'-deoxycytidine
CAS :<p>N-Pyrrolo-2'-deoxycytidine is a nucleoside analog that is used in the laboratory as a template for DNA synthesis. It has been shown to be an effective inhibitor of human pathogens. N-Pyrrolo-2'-deoxycytidine binds to DNA and prevents replication by interfering with the binding of the enzyme polymerase to the template strand, which leads to denaturation of the complementary strand and blocking of DNA elongation. This drug has been shown to bind specifically to sequences that are unpaired in duplexes, such as single-stranded telomeres. N-Pyrrolo-2'-deoxycytidine can also be used as a fluorescence probe for detecting dsDNA duplexes.</p>Formule :C12H15N3O4Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :265.27 g/mol2'-Deoxy-2-methoxyadenosine
CAS :<p>2'-Deoxy-2-methoxyadenosine is a nucleoside that has been isolated from the sponge Spongospora. It is a glycosylated nucleoside that contains a formamidine chromophore and an amino function. The molecule has been synthesized by solid-phase synthesis, which involves the use of phosphoramidite chemistry to attach a series of building blocks onto an oligonucleotide template. 2'-Deoxy-2-methoxyadenosine was found to have thermal stability in phosphate buffer solutions and low reactivity with nucleophiles such as ammonia or methylamine. This nucleoside can be used as a substituent in synthetic organic chemistry and has been shown to inhibit the growth of bacteria such as Clostridium perfringens.</p>Formule :C11H15N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :281.27 g/mol2',3'-Dideoxy-5'-O-DMT-uridine
CAS :<p>2',3'-Dideoxy-5'-O-DMT-uridine is a nucleoside for use in research applications</p>Formule :C30H30N4O6Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :514.58 g/mol2'-Deoxypseudouridine
CAS :<p>2'-Deoxypseudouridine is a nucleotide that is synthesized from the sugar ribose-5-phosphate and uracil. It is used in biological systems to transfer phosphate groups, which are vital to the metabolism of energy. 2'-Deoxypseudouridine also binds to DNA, forming stable complexes with enzymes and other molecules. This nucleotide is often found in oligodeoxynucleotides, which are used as antiviral agents. 2'-Deoxypseudouridine has been shown to have antimicrobial activity against various viruses, including hepatitis B virus (HBV). It has also been tested for its ability to inhibit replication of HIV-1 in vitro. The enzyme glycosylase catalyzes the reaction of 2'-deoxypseudouridine with water, producing an unstable intermediate that spontaneously converts into dUMP and pyrophosphate.</p>Formule :C9H12N2O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :228.21 g/mol5'-O-Benzoyl-2'-deoxyinosine
5'-O-Benzoyl-2'-deoxyinosine is an antiviral agent that inhibits the replication of certain viruses. It is a nucleoside analog that contains a benzoyl group at the 5' position and a 2'-deoxyribose sugar moiety. It has been shown to inhibit the growth of cancer cells in vitro and to produce cytotoxic effects on human lymphocytes. This compound is synthesized by reacting an appropriate ribonucleotide with phosphoramidite reagents, which are used as starting materials for DNA synthesis.Degré de pureté :Min. 95%Uridine-5-oxyacetic acid
CAS :<p>Uridine-5-oxyacetic acid is a molecule that is synthesized from uridine and 5-oxo-4-pyrone. It is an intermediate in the synthesis of pyrimidine nucleotides, which are important for DNA replication, repair, and transcription. Uridine-5-oxyacetic acid has been shown to form stable complexes with subtilisin. These complexes have been determined by X-ray crystallography to be glycosidic bond between the uridine and the enzyme. The enzymatic activity of subtilisin can be inhibited by these complexes, which may lead to frameshifting during bacterial translation. This inhibition leads to a less efficient protein synthesis process and a decrease in the production of gene products.</p>Formule :C11H14N2O9Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :318.24 g/molMalonyl coenzyme A lithium salt - 97%
CAS :<p>Malonyl-CoA is a metabolite that regulates the storage of fat and the production of energy in adipose tissue. Malonyl coenzyme A lithium salt is a fatty acid, which has been shown to reduce insulin resistance in response to diet in mice. It also has an anti-obesity effect by lowering body weight and reducing fat mass accumulation. The mechanism for this is not fully understood but may involve regulation of tnf-α activity and adipocyte hypertrophy.</p>Formule :C24H37N7O19P3S·xLiDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :852.57 g/mol3'-Deoxyuridine
CAS :<p>3'-Deoxyuridine is a synthetic antibiotic that is used in the treatment of viral infections, such as hepatitis B and C, and HIV. 3'-Deoxyuridine competitively inhibits the synthesis of RNA by binding to the enzyme RNA polymerase. This drug also has antiviral activity against the human cytomegalovirus (CMV) and Hepatitis C virus (HCV). 3'-Deoxyuridine is synthesized from uracil in an organic solvent, trifluoroacetic acid, at low temperatures. The incorporation of deoxynucleoside triphosphates into DNA occurs after cleavage of the terminal phosphate group by water vapor.</p>Formule :C9H12N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :228.21 g/mol2',3'-Dideoxyguanosine
CAS :<p>2',3'-Dideoxyguanosine is a nucleoside for use in research applications</p>Formule :C10H13N5O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :251.25 g/mol4'-Thioadenosine
CAS :4'-Thioadenosine is a nucleoside that has been shown to inhibit the growth of leukemia cells by binding to adenosine receptors. It is also able to inhibit the activity of the mammalian phosphodiesterase PDE4, which is responsible for hydrolyzing cAMP. The cellular effects of 4'-thioadenosine can be seen in HL-60 human cells, and this drug has also shown promising results in animal models of kidney fibrosis and liver cirrhosis. 4'-Thioadenosine has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.Formule :C10H13N5O3SDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :283.31 g/molThymidylyl-3'-5'-thymidine ammonium
CAS :<p>Thymidylyl-3'-5'-thymidine ammonium is a cytotoxic drug that belongs to the class of thymidylate synthase inhibitors. It inhibits enzymes responsible for DNA synthesis and repair by binding to the active site of these enzymes and forming covalent bonds with amino acid residues. Thymidylyl-3'-5'-thymidine ammonium can be used as a therapeutic agent in radiation therapy because it is more effective than other drugs at inhibiting cell growth. Thymidylyl-3'-5'-thymidine ammonium has been shown to inhibit the activity of carcinogenic compounds, such as benzo[a]pyrene and benzene, in a model system. Thymidylyl-3'-5'-thymidine ammonium also has the ability to form covalent bonds with dna duplexes and change their conformational properties.</p>Formule :C20H27N4O12P·NH3Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :563.45 g/mol6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one
CAS :6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one is a novel nucleoside that has been shown to have anticancer and antiviral properties. In vitro studies have shown the compound to activate both DNA and RNA synthesis in cells. The compound also inhibits the replication of HIV viruses. 6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one is synthesized from ribonucleosides or deoxyribonucleosides through phosphoramidite chemistry. This product is available in high purity and high quality.Formule :C11H15N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :269.25 g/molGuanosine 5'-diphosphate disodium salt
CAS :Guanosine 5'-diphosphate (GDP) disodium salt is a nucleoside dipsphate and a pyruvate kinase substrate, which converts GDP to GTP.Formule :C10H13N5O11P2·2NaDegré de pureté :Min. 90 Area-%Couleur et forme :White PowderMasse moléculaire :487.17 g/mol5-Fluorouridine
CAS :<p>5-Fluorouridine, also called 1-(b-D-ribofuranosyl)-5-fluorouracil and 5-fluoro-D-uridine (FUrd), is a modified uridine nucleoside with a fluorine atom at position 5 of the uracil. 5-Fluorouridine is a highly cytotoxic metabolite of 5-fluorouracil, a drug used to treat a variety of cancers, on the market with the trade name Adrucil. Prodrugs of 5-fluorouridine have been investigated for anti-tumour properties in their own right and are close structural analogues of 5'-deoxy-5-fluorouridine, a cytostatic agent in chemotherapy.</p>Formule :C9H11FN2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :262.2 g/mol2'-Deoxycytidine
CAS :<p>2'-Deoxycytidine is a deoxyribonucleotide that is used in the synthesis of DNA. It has been shown to have potent antitumor activity against solid tumours and may be useful for the treatment of leukemic mice. This compound has been shown to inhibit the kinase activity of IL-2 receptor and Toll-like receptor, which are proteins that regulate the immune response. 2'-Deoxycytidine also inhibits DNA polymerase activity and thermal expansion, which may make it a good candidate as an anticancer drug.</p>Formule :C9H13N3O4Degré de pureté :Min. 99 Area-%Couleur et forme :PowderMasse moléculaire :227.22 g/mol1-(3'-5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-α-L-arabinofuranosyl)thymine
1-(3`-5`-Di-O-benzoyl-2`-deoxy-2`-fluoro-alpha-L-arabinofuranosyl)thymine is a nucleoside analog with modifications that influence its biological activity. It is made up of a thymine base, benzoyl groups that protect hydroxyl functionalities during chemical synthesis and a α-L-linkage, which impacts its biological interactions compared to β-L-nucleosides. This molecule also contains the sugar 2'-Deoxy-2'-fluoro-α-L-arabinofuranose which has a L-arabinose configuration, an α-Anomeric linkage and a 2'-Fluoro substitution. The latter modification has the potential to increase the molecule's metabolic stability and resistance to enzymatic degradationFormule :C24H21FN2O7Degré de pureté :Min. 95%Masse moléculaire :484.89 g/molThymidine
CAS :<p>Thymidine is a nucleoside that is found in cells and is involved in the synthesis of DNA. Thymidine has been shown to inhibit the growth of tumor cells through apoptosis. In addition, thymidine can be used for the treatment of bowel disease by reducing inflammation and increasing the production of mucin. The mechanism by which thymidine exerts its effects on tumor cells is not well understood, but it may involve interactions with dna binding activity and enzyme activities.</p>Formule :C10H14N2O5Degré de pureté :Min. 99 Area-%Masse moléculaire :242.23 g/molRef: 3D-Q-201829
1kgÀ demander5kgÀ demander250gÀ demander500gÀ demander2500gÀ demander-Unit-kgkgÀ demander2'-Deoxy-6-thioguanosine
CAS :2'-Deoxy-6-thioguanosine is a purine nucleoside analog that inhibits the activation of transcription factors such as nuclear factor kappa-B (NF-κB) and activator protein 1 (AP-1). It also inhibits the synthesis of proinflammatory cytokines, such as IL-1β, IL-6, and TNFα. The matrix effect is an important factor in the prevention of tumor progression. 2'-Deoxy-6-thioguanosine has been shown to inhibit cell proliferation and induce apoptosis in squamous cell carcinoma cells by modulating the expression of HLA class II molecules on tumors. It also prevents invasion by blocking matrix metalloproteinase activity. 2'-Deoxy-6-thioguanosine has been found to be effective against bowel diseases such as ulcerative colitis and Crohn's disease, as well as infectious diseases such as HIV/AIDS.Formule :C10H13N5O3SDegré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :283.31 g/mol5'-O-DMT-a-thymidine
<p>5'-O-DMT-a-thymidine is a modified nucleoside that is used in the synthesis of DNA and RNA. This product is a high quality and pure monophosphate, which has been modified to reduce its potential for activation by phosphatases. It is suitable for use in anticancer drugs and antiviral agents.</p>Formule :C31H32N2O7Degré de pureté :Min. 95%Masse moléculaire :544.6 g/mol2'-Deoxy-L-cytidine
CAS :<p>2'-Deoxy-L-cytidine is a nucleoside that is naturally found in the cells of E. coli K-12. It is an antioxidant compound that prevents lipid peroxidation and scavenges free radicals, which are generated by certain chemical reactions. 2'-Deoxy-L-cytidine has been shown to have antiviral potency in vitro, but its antiviral activity has not been evaluated in vivo. This compound also inhibits the growth of bacteria that are resistant to tetracycline, such as Mycobacterium tuberculosis and Helicobacter pylori. 2'-Deoxy-L-cytidine may cause drug interactions with other medications because it is metabolized by the CYP450 system and inhibits the activity of cytochrome P450 enzymes.</p>Formule :C9H13N3O4Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :227.22 g/mol
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