Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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3'-Azido-5'-O-benzoyl-3'-deoxythymidine
CAS :<p>3'-Azido-5'-O-benzoyl-3'-deoxythymidine is a novel antiviral agent that is synthesized by modifying the structure of thymidine. It has been shown to have high antiviral activity against HIV and other viruses in vitro. 3'-Azido-5'-O-benzoyl-3'-deoxythymidine also inhibits tumor growth in animal models and may be useful as an anticancer drug. This compound is found to be active against a number of cancers, including leukemia, colon cancer, and prostate cancer. 3'-Azido-5'-O-benzoyl-3'-deoxythymidine is phosphoramidites for DNA synthesis, which can be used in the production of ribonucleosides or deoxyribonucleosides.</p>Formule :C17H19N5O4Degré de pureté :Min. 95%Masse moléculaire :357.36 g/molCytidine 3',5'-cyclic monophosphate monosodium
CAS :<p>Cytidine 3',5'-cyclic monophosphate monosodium is a phosphotriester that is used as a building block to synthesize ribonucleosides, uridine, guanosine, and cytidine. The phosphate group in the molecule can be removed by nucleophilic substitution with ammonia or sodium hydroxide to form the corresponding nucleosides. Cytidine 3',5'-cyclic monophosphate monosodium has been shown to inhibit bacterial growth.</p>Formule :C9H11N3O7PNaDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :327.16 g/moltrans-Zeatin riboside-5'-monophosphate sodium salt
CAS :<p>Trans-zeatin riboside-5'-monophosphate sodium salt is a growth rate inhibitor that inhibits protein synthesis by binding to the 30S subunit of the ribosome. This compound has been shown to inhibit cell growth and proliferation in vitro when applied to tissue cultures of tabacum l. and other plants. Trans-zeatin riboside-5'-monophosphate sodium salt is not active against plant tissues grown in vivo, which may be due to its inability to cross the plasma membrane or cell wall.</p>Formule :C15H20N5O8PNa2Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :475.3 g/molL-Guanosine
CAS :<p>L-Guanosine is an enantiomer of adenosine. It has been shown to be effective in the treatment of autoimmune diseases and viruses, such as HIV. L-Guanosine is activated by phosphorylation, which leads to its binding with DNA and inhibition of viral replication. L-Guanosine is also a potent inhibitor of mammalian cell proliferation. It binds to the enzyme adenosyltransferase, thereby inhibiting the production of nucleotides, which are necessary for DNA synthesis. This inhibition causes cell death due to lack of DNA synthesis and protein production.</p>Formule :C10H13N5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :283.24 g/mol5-Cyanouridine
CAS :<p>5-Cyanouridine is a pyrimidine nucleoside that is synthesized from uracil. It is a potent inhibitor of the enzyme decarboxylase, which catalyzes the conversion of 5-cytosine to 5-uracil, and has been used for the treatment of malignant lymphoma. 5-Cyanouridine is also a substrate for DNA replication and can be used as a target for antiviral drugs. The drug inhibits viral RNA synthesis by acting on the vesicular stomatitis virus (VSV) in two different ways: first, by inhibiting viral RNA polymerase activity; second, by incorporation into viral DNA. This incorporation can lead to chain termination or to translesion synthesis. 5-Cyanouridine has been shown to inhibit VSV replication in cell culture at concentrations as low as 1 μM.</p>Formule :C10H11N3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :269.21 g/mol5,6-Dihydro-5-methyluridine
CAS :<p>5,6-Dihydro-5-methyluridine is a nucleoside that is found in the human genome. It is a precursor of uridine and can be used to synthesize 5-methylcytosine, which is an epigenetic modification that occurs in DNA. This modification can affect the expression of genes by changing the structure of chromatin. This drug has been identified as a potential drug target for cancer treatment and other diseases. Structural analysis has shown that this compound has a number of hydrogen bonds with oxygen atoms and hydroxyl groups, which may make it more effective than other drugs currently being studied. 5,6-Dihydro-5-methyluridine forms a phylogenetic tree with other compounds that are also found in the human genome, suggesting that it may have evolved through natural selection.</p>Formule :C10H16N2O6Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :260.24 g/molAdenosine 5'-phosphosulfate sodium salt, 10 mM in water
CAS :<p>Adenosine 5′-phosphosulfate sodium salt has been used quantify pyrophosphate and in enzyme-linked bioluminescence assay for adenosine triphosphate (ATP).Product provided as 10 mM solution in water.</p>Formule :C10H14N5O10PSDegré de pureté :Min. 90.0 Area-%Masse moléculaire :427.28 g/mol5-Carboxyhydroxymethyluridine
CAS :<p>5-Carboxyhydroxymethyluridine is a hydroxylated nucleoside that is used to study DNA repair. It is a nucleotide analogue that has been modified at the hydroxyl group by methylation. 5-Carboxyhydroxymethyluridine can be converted back to uridine by escherichia coli hydroxylases, but this conversion does not occur in vivo. 5-Carboxyhydroxymethyluridine can be used as a substrate for methyltransferase enzymes, which are involved in DNA repair. The enzyme 5'-methylthioadenosine phosphorylase converts 5-carboxyhydroxymethyluridine into S-adenosylhomocysteine and adenine. This conversion can be reversed by the enzyme methionine synthase. Some homologues of 5-carboxyhydroxymethyluridine have been found in nature and other modifications have been made on the</p>Formule :C11H14N2O9Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :318.24 g/mol5'-O-DMT-2'-O-methylcytidine
CAS :<p>5'-O-DMT-2'-O-methylcytidine is a monophosphate nucleoside of cytidine. It is used as an antiviral agent and has been shown to have anticancer effects in vitro. 5'-O-DMT-2'-O-methylcytidine is synthesized by modification of the natural deoxyribonucleosides, which are then phosphoramidited to form a 5'-O-DMT-2'-O-methylcytidine monophosphate. The synthesis process also produces diphosphate and triphosphate forms of the nucleoside, which can be used for other purposes.</p>Formule :C31H33N3O7Degré de pureté :Min. 95%Masse moléculaire :559.61 g/molGlycinamide ribonucleotide
CAS :<p>Glycinamide ribonucleotide (GAR) is a reactive metabolite that is formed from glycinamide, which is an intermediate in the synthesis of purines. GAR has been shown to bind to intracellular targets and inhibit their enzyme activities. GAR has been shown to inhibit the activity of enzymes that are involved in the synthesis of purines, such as ribonucleotides and nucleoside phosphates. These enzymes have been found in human tissues. GAR also inhibits the polymerase chain reaction (PCR) by binding to DNA and inhibiting its replication. This drug has also been shown to be effective against bowel disease by binding to bacterial dna gyrase, dna topoisomerase, and rna synthesis.</p>Formule :C7H15N2O8PDegré de pureté :Min. 80 Area-%Couleur et forme :PowderMasse moléculaire :286.18 g/molN1-Methyladenosine
CAS :<p>N1-Methyladenosine is a nucleoside that has been shown to inhibit the synthesis of proteins in the ribosome, which are essential for all cellular functions. N1-Methyladenosine has been shown to be effective against HIV infection, and has also been used as a chemotherapeutic agent in cancer cells. The optimum concentration of this drug is unknown, but it is known that at high concentrations, it can cause cellular death. N1-Methyladenosine has also been shown to be effective in treating metabolic disorders and autoimmune diseases.</p>Formule :C11H15N5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :281.27 g/molC2-Methyladenosine
CAS :<p>C2-Methyladenosine is a x-ray crystal structure of the mutant strain of Mycobacterium tuberculosis that has an efficient method for binding to the substrate. The uptake of C2-methyladenosine by the wild type strain was found to be at least four times higher than that of adenosine. The analog was also shown to have pharmacokinetic properties in fat cells, which leads to a decrease in ATP levels.</p>Formule :C11H15N5O4Degré de pureté :Min. 96 Area-%Couleur et forme :White PowderMasse moléculaire :281.27 g/molN3-Methylcytidine methosulfate
CAS :<p>N3-Methylcytidine methosulfate is a novel antiviral agent that inhibits the synthesis of DNA and RNA. It has been shown to be effective against hepatitis B virus, herpes simplex virus, varicella-zoster virus, human immunodeficiency virus, and cytomegalovirus. N3-Methylcytidine methosulfate was found to be active in a variety of animal models including mice and rats. This drug has anticancer properties in the treatment of leukemia, lymphoma, and breast cancer. The phosphoramidite derivative of N3-methylcytidine methosulfate is used as an activator for oligonucleotide synthesis.</p>Formule :C10H15N3O5·CH4SO4Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :369.35 g/molN6-Ethenoadenosine
CAS :<p>N6-Ethenoadenosine is a fluorescent derivative that is used in biology to study the binding of receptor molecules to DNA. N6-Ethenoadenosine binds to the dinucleotide phosphate, which is an important component for many metabolic processes. It also has been shown to be an effective inhibitor of DNA duplexes and ATPase activity. N6-Ethenoadenosine has a glycosidic bond with p-nitrophenyl phosphate, which is a substrate of creatine kinase and can be used as an indicator of its activity. This product is also used as a marker for damaged DNA.</p>Formule :C12H13N5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :291.26 g/molGuanosine 3',5'-cyclic monophosphate
CAS :<p>Guanosine 3',5'-cyclic monophosphate (cGMP) is a nucleotide that functions as a second messenger in the cell. It is involved in many cellular processes, including mitochondrial functions and energy metabolism. cGMP is synthesized from guanosine triphosphate (GTP) by the enzyme guanine nucleotide-binding protein, which hydrolyzes the phosphate group from GTP to form cGMP. cGMP has been shown to be involved in neuronal death, axonal growth, and glucose uptake in cells. Optimum concentrations of cGMP have been found to be between 1-10 μM. It has also been shown to be an important mediator of cyclic axonal growth and bowel disease. Guanosine 3',5'-cyclic monophosphate can also act as a polymerase chain reaction primer for DNA amplification in vitro.</p>Formule :C10H12N5O7PDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :345.21 g/mol2-Chloroisonicotinic acid
CAS :<p>2-Chloroisonicotinic acid is a halogenated derivative of isonicotinic acid where a chlorine atom is substituted at the 2-position of the pyridine ring (next to the carboxylic acid group).</p>Formule :C6H4ClNO2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :157.55 g/mol2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate triethylammonium salt - Aqueous solution
CAS :<p>2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate triethylammonium salt - Aqueous solution is a nucleoside analog for research purposes</p>Formule :C9H14F2N3O13P3·C24H60N4Couleur et forme :Colorless PowderMasse moléculaire :907.9 g/mol2'-Deoxy-2'-fluoro-5-methylcytidine
CAS :<p>2'-Deoxy-2'-fluoro-5-methylcytidine is a nucleoside analog that is a modified version of cytidine, where the sugar (deoxyribose) has a fluoro modification at the 2' carbon and a methyl group is attached at the 5' position of the cytosine base. This modification confers unique properties that can be useful in research and drug development.</p>Formule :C10H14FN3O4Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :259.23 g/molN4-Ethenocytidine
CAS :<p>N4-Ethenocytidine is a nucleoside analogue that has been synthesized and shown to be an effective inhibitor of the hepatitis C virus. N4-Ethenocytidine prevents the synthesis of viral RNA by attacking the 3'-hydroxyl group of uridine, which is involved in the formation of ribonucleotides. This compound can also inhibit rat liver microsomes through a hydrated attack on carbonyl groups. The reaction products are trifluoroacetic acid and chloride ions. N4-Ethenocytidine's fluorescence properties have been used to identify its reaction intermediates, which include uridylic acid and 4-etheno-N6-isopentenyladenosine.</p>Formule :C11H13N3O5Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :267.24 g/mol5'-O-DMT-2'-O-methyluridine
CAS :<p>5'-O-DMT-2'-O-methyluridine (5'-OMeT) is a phosphoramidite building block of a modified nucleoside that is used in biological research. The stability of 5'-OMeT has been studied by thermal denaturation studies and found to be more stable than other analogues such as 6-azacytidine, 6-azauridine, and 6-azathymidine. This may be due to its increased resistance to endonucleolytic cleavage. 5'-OMeT has not shown any significant biological activity in vivo or in vitro.</p>Formule :C31H32N2O8Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :560.61 g/mol8-(4-Chlorophenylthio)adenosine 3',5'-cyclic monophosphate monosodium salt
CAS :<p>8-(4-Chlorophenylthio)adenosine 3',5'-cyclic monophosphate monosodium salt (8-CPT-cAMP) is a cytosolic second messenger that regulates physiological processes. It interacts with the G protein coupled receptor 2-adrenergic receptor, and activates adenylyl cyclase to produce cAMP. 8-CPT-cAMP also induces mitochondrial membrane potential depolarization and Ca2+ release from the endoplasmic reticulum, which leads to cell death. The pro-apoptotic protein Bax is upregulated by 8-CPT-cAMP in cells and contributes to cell death.</p>Formule :C16H14ClN5NaO6PSDegré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :493.79 g/mol2',3'-Di-O-acetyladenoside
CAS :<p>2',3'-Di-O-acetyladenoside is a nucleoside for use in research applications</p>Formule :C14H17N5O6Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :351.31 g/mol2'-O-Methylguanosine
CAS :<p>2'-O-Methylguanosine is a nucleoside that contains a 2'-O-methyl group at the 2' position of the ribose. It is a component of many nucleic acids and is usually found as a minor component in RNA. 2'-O-Methylguanosine has been shown to be an inhibitor of DNA polymerase and an activator of RNA polymerase, which may be due to its ability to form hydrogen bonds with the phosphate backbone. This compound has also been shown to act as a competitive inhibitor for both wild-type and mutant bacterial strains, suggesting that it can inhibit DNA synthesis in bacteria by binding to the enzyme's active site. 2'-O-Methylguanosine is present in relatively high concentrations in tissues, such as liver and muscle, where it is involved in metabolism or energy production. The optimum concentration for detection by analytical methods varies depending on the type of detector used.</p>Formule :C11H15N5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :297.27 g/mol3'-O-Methylguanosine
CAS :<p>3'-O-Methylguanosine is a nucleoside that is found in the guanine molecule and has been shown to have inhibitory properties against malignant brain tumors. 3'-O-Methylguanosine blocks the synthesis of DNA, RNA, and peptide hormones. It also inhibits the growth of erythromycin-resistant strains of bacteria. The kinetic data for 3'-O-Methylguanosine was obtained from experiments with leukemic mice and carcinoma cell lines. The enzyme glut1 regulates the rate of metabolism of 3'-O-Methylguanosine. It is metabolized by dehydroascorbic acid reductase to 3'-deoxyadenosine monophosphate (dAMP) and then to adenosine monophosphate (AMP). The optimum pH for this reaction is 7.3 at 37 degrees Celsius.</p>Formule :C11H15N5O5Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :297.27 g/mol5-Hydroxycytidine
CAS :<p>5-Hydroxycytidine is a pyrimidine nucleoside that is found in DNA and RNA. It can be produced by the conversion of cytidine 5-monophosphate to cytidine 5'-diphosphate, which is then hydrolyzed to produce 5-hydroxycytidine. This conversion requires the enzyme cytidylate kinase. The structure of 5-hydroxycytidine differs from other pyrimidine nucleosides as its hydroxyl group does not have an acidic proton present. Biological functions that have been attributed to 5-hydroxydihydrocytidylic acid include its ability to inhibit translation and induce cell death in lung cells. This compound has also been shown to modify DNA duplexes and form bioconjugates with proteins or small molecules, such as fluorescein and digoxigenin. These modifications are used in analytical methods such as phase chromatography, nuclear magnetic resonance spectroscopy</p>Formule :C9H13N3O6Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :259.22 g/mol8-Bromoguanosine hydrate
CAS :<p>8-Bromoguanosine hydrate is a brominated form of guanosine. It is used as a marker for colorectal cancer in urine samples. 8-Bromoguanosine hydrate can be used to calibrate the results of chromatographic analyses and to identify metabolic disorders, such as fatty acid oxidation defects. The compound is also an endogenous ligand that interacts with adenosine receptors and may have pro-apoptotic effects on cancer cells by triggering their death. 8-Bromoguanosine hydrate has been shown to be more effective than other brominated nucleosides in inducing apoptosis in malignant cells, including colorectal carcinoma cells.</p>Formule :C10H12BrN5O5·xH2ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :362.14 g/mol2'-Deoxy-5-hydroxymethylcytidine
CAS :<p>2'-Deoxy-5-hydroxymethylcytidine is a nucleoside analog that inhibits the enzyme thymidylate synthase. The inhibition of this enzyme leads to a deficiency in the production of thymine, which is essential for DNA synthesis. 2'-Deoxy-5-hydroxymethylcytidine has been shown to be an effective anti-cancer agent in vitro and in vivo. It can also be used as a potential biomarker for cancer and can be used as a polymerase chain reaction (PCR) primer for detection of cancer tissue. This drug binds to the polymerase enzyme, preventing it from performing its function to replicate DNA, thereby halting cell division and causing cell death.</p>Formule :C10H15N3O5Degré de pureté :Min. 95%Couleur et forme :White Yellow PowderMasse moléculaire :257.24 g/mol3'-O-Propargyluridine
CAS :<p>3'-O-Propargyluridine is a synthetic nucleoside with an alkyne functional handle on the 3'-position of the sugar</p>Formule :C12H14N2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :282.25 g/mol5-(Methylaminomethyl)-2-thiouridine
CAS :<p>5-(Methylaminomethyl)-2-thiouridine is a nucleotide that is important for both DNA and RNA synthesis. It is the methyl donor in the formation of dTMP, an essential component of DNA. 5-(Methylaminomethyl)-2-thiouridine is synthesized by the enzyme thioredoxin reductase using NADPH and glutathione as cofactors. The synthesis of this nucleotide is regulated by hydrogen bonding, which may be due to its ability to form a cationic surfactant with a molecule such as typhimurium. This activity may be due to the presence of a disulfide bond that can react with other molecules such as guanine nucleotides.<br>5-(Methylaminomethyl)-2-thiouridine has been shown to have structural analysis and chemical biology applications when used in conjunction with E. coli K-12 cells, Methanobrevib</p>Formule :C11H17N3O5SDegré de pureté :(¹H-Nmr) Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :303.34 g/mol2-Chloro-2',3'-O-isopropylideneadenosine
CAS :<p>2-Chloro-2',3'-O-isopropylideneadenosine is a novel, anti-cancer drug that inhibits the synthesis of DNA. It is a phosphoramidite monophosphate with a molecular weight of 288.08 g/mol and an empirical formula C6H12ClNO5PS. The chemical name for this compound is 2-chloro-N-(2,3-diisopropyl)adenine diphosphate. This product has not yet been approved by the FDA for use in humans or animals.</p>Formule :C13H16ClN5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :341.75 g/molN4-Acetyl-2'-deoxy-2'-fluorocytidine
CAS :<p>N4-Acetyl-2'-deoxy-2'-fluorocytidine is a chemical compound that has been the subject of recent research in the field of complex system. It is an aromatic compound that is found in β-pinene, monoterpenes, and other plant products. N4-Acetyl-2'-deoxy-2'-fluorocytidine has not been shown to have any significant biological activity.</p>Formule :C11H14FN3O5Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :287.24 g/molCaged GTP
CAS :<p>Caged GTP is a modified nucleotide that is biologixally inactive until exposed to ultraviolet light, where GTP is released.</p>Formule :C18H23N6O16P3Degré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :672.33 g/mol2',3'-Dideoxyadenosine
CAS :<p>2',3'-Dideoxyadenosine is a nucleoside analog that inhibits HIV replication and is a competitive inhibitor of adenylyl cyclase. This latter action reduces levels of cyclic adenosine monophosphate (cAMP)</p>Formule :C10H13N5O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :235.25 g/mol5'-Deoxy-5'-iodoguanosine
CAS :<p>5'-Deoxy-5'-iodoguanosine is a synthetic nucleoside that is used as a molecular probe to study the biochemical and physiological effects of UV irradiation. It has been shown to be reactive under in vitro conditions, and to have functionalities in vivo. 5'-Deoxy-5'-iodoguanosine has been used as a polymerase inhibitor, and it can also be used for the synthesis of oligonucleotides.</p>Formule :C10H12IN5O4Degré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :393.14 g/mol2'-Deoxy-5'-O-DMT-N6-methyladenosine
CAS :<p>2'-Deoxy-5'-O-DMT-N6-methyladenosine is a mutant of the natural nucleoside adenosine which has been synthesized as a model for the study of the enzyme ribonucleotide reductase. The mutant has a frameshift mutation, and the resulting protein is unable to catalyze DNA synthesis. It can be complemented by adding wild type nucleotides to regenerate the original sequence. 2'-Deoxy-5'-O-DMT-N6-methyladenosine inhibits the synthetase activity of ribonucleotide reductase and also inhibits polymerization of erythromycin B and styrene.<br>2'-Deoxy-5'-O-DMT-N6-methyladenosine has been shown to inhibit dehydrogenase activity in auxotrophs of Escherichia coli.</p>Formule :C32H33N5O5Degré de pureté :Min. 98 Area-%Couleur et forme :Off-White PowderMasse moléculaire :567.64 g/mol5-Chloro-5'-deoxyuridine
<p>5-Chloro-5'-deoxyuridine is a nucleoside that is used as an antiviral agent and anticancer drug. It inhibits the viral DNA polymerase by acting as a phosphoramidite in the synthesis of viral DNA. 5-Chloro-5'-deoxyuridine is also used in the treatment of leukemia cells, which are resistant to other anticancer drugs. The high purity and modified nucleosides make this product highly desirable for research purposes. The novel syntheses of this product make it a desirable choice for many researchers.</p>Formule :C9H11ClN2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :262.65 g/mol2'-Deoxy-N2-DMF-guanosine
CAS :<p>2'-Deoxy-N2-DMF-guanosine is a synthetic nucleoside that is used as a primer in DNA sequencing and hybridization experiments. It binds to the 5' end of single-stranded DNA and is complementary to guanosine. The 2'-deoxy group on the sugar moiety prevents the formation of hydrogen bonds with other bases, which increases stability. In addition, it has a high affinity for dna binding proteins. This synthetic nucleoside has been shown to be useful in clinical diagnostics and can be used as a probe for detecting diazirine residues in DNA sequences.</p>Formule :C13H18N6O4Degré de pureté :Min. 97 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :322.33 g/mol2'-Deoxyuridine
CAS :<p>2'-Deoxyuridine (2'-dU) is an intermediate in the synthesis of thymidylate, which is a precursor for DNA synthesis. It can be prepared through high-performance liquid chromatography. 2'-dU has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death. 2'-dU has also been shown to have a protective effect against mitochondrial dysfunction induced by hydrogen fluoride. It is also known to bind with toll-like receptor 4 (TLR4), which is involved in inflammatory responses. 2'-dU has been used as a fluorescence probe for nucleic acids and as a polymerase chain reaction (PCR) substrate.</p>Formule :C9H12N2O5Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :228.21 g/mol3'-Amino-2',3'-dideoxyguanosine
CAS :<p>3'-Amino-2',3'-dideoxyguanosine's lack of a 3'-hydroxyl group makes it a chain terminator for DNA polymerase, a key application in Sanger sequencing. Additionally, the 3'-amino group serves as a functional handle for modifying the 3' end of oligonucleotides with various labels or conjugates, expanding their utility in research and diagnostics.</p>Formule :C10H14N6O3Degré de pureté :(%) Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :266.26 g/mol2-Thiouridine
CAS :<p>2-Thiouridine is a uridine derivative that acts as a precursor for protein synthesis. It is synthesized from 2-amino-5-thiazole carboxylic acid and uracil in two steps, first with the formation of 2-thiouridine monophosphate and then with the conversion to 2-thiouridine diphosphate. The synthesis of 2-thiouridine is catalyzed by the enzyme uridine phosphorylase, which converts it to uridine monophosphate. 2-Thiouridine has been shown to have immunomodulatory effects in cell culture systems and animal models. These effects are believed to be due to its ability to act as an inhibitor of fatty acid synthase, which generates fatty acids from acetyl CoA. This process prevents the production of prostaglandins and leukotrienes, thereby reducing inflammation.</p>Formule :C9H12N2O5SDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :260.27 g/molXanthosine 5'-monophosphate disodium salt
CAS :<p>Xanthosine 5'-monophosphate disodium salt is a nucleotide that has been shown to react with nitrite in aqueous solution to form xanthosine 5'-monophosphate. The reaction system can be prepared by adding nitrite to a solution of xanthosine 5'-monophosphate disodium salt and deionized water. The crystallization process can be done by adding ethanol dropwise to the reaction system under controlled conditions. Impurities may result from the preparation process, such as sodium chloride, sodium sulfate, and sodium hydroxide.</p>Formule :C10H11N4Na2O9PDegré de pureté :Min. 95%Couleur et forme :White Slightly Yellow PowderMasse moléculaire :408.17 g/mol2'-Deoxy-N3-methyluridine
CAS :<p>2'-Deoxy-N3-methyluridine is a nucleoside analog that is used as a substrate in the synthesis of DNA. It can be incorporated into the DNA strand by enzymes called thymidylate synthases. 2'-Deoxy-N3-methyluridine has been shown to inhibit bacterial growth in cell cultures, and it is also active against marine sponges. The protonation state of the molecule determines its hydrophobicity and can be altered by adding a test compound to the solution. Hydrophobic molecules are more likely to bind with water molecules than hydrophilic molecules, which are more soluble in water.</p>Formule :C10H14N2O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :242.23 g/mol2',3'-Dideoxyuridine
CAS :<p>Research tool for anti-viral and anti-cancer studies</p>Formule :C9H12N2O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :212.21 g/molN4,N4-Dimethylcytidine
CAS :<p>N4,N4-Dimethylcytidine is a nucleoside that is an analog of cytidine. It has antiviral potency against influenza virus and inhibits the RNA-dependent DNA polymerase. N4,N4-Dimethylcytidine can be used to treat influenza and other viruses that are resistant to other antiviral drugs. This drug can be used in cell culture to inhibit the production of mismatched DNA strands, which is important for the replication of RNA viruses such as influenza. N4,N4-Dimethylcytidine also has been shown to be an inhibitor of miRNA activity in mammalian cells.</p>Formule :C11H17N3O5Degré de pureté :(%) Min. 95%Couleur et forme :White PowderMasse moléculaire :271.27 g/molN4-Benzoyl-2'-O-methylcytidine
CAS :<p>N4-Benzoyl-2'-O-methylcytidine is a triester of cytidine that is used in various biochemical research applications. It is enzymatically synthesized from cytidine and benzoyl chloride. N4-Benzoyl-2'-O-methylcytidine has been shown to have the same electrophoretic mobility as 5-hydroxyl cytidine, but it does not react with hydroxylamine to produce the corresponding hydroxylated product. This compound has also been used to study nucleic acid structure and function.</p>Formule :C17H19N3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :361.35 g/mol6-Methylpurine-2'-deoxyriboside
CAS :<p>6-Methylpurine-2'-deoxyriboside (6MPdR) is a nucleoside analog that inhibits viral polymerase activity. It is used in the treatment of bowel diseases, such as inflammatory bowel disease and hepatitis C. 6MPdR can be used to treat cancer by inhibiting cellular proliferation and inducing apoptosis. This drug has been shown to inhibit leishmania growth in cell culture. 6MPdR can be administered orally or intravenously, and is pegylated for greater stability in the blood stream.</p>Formule :C11H14N4O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :250.25 g/molCoenzyme A hydrate
CAS :<p>Coenzyme A hydrate is essential in the metabolism of fatty acids and the synthesis of acetyl-CoA. It is also employed in pharmaceutical applications, especially in drug development and formulation. Its distinctive properties improve drug solubility and bioavailability, making it an essential component in the creation of therapeutic agents.</p>Formule :C21H36N7O16P3S·xH2ODegré de pureté :(Enzymatic) Min. 75%Couleur et forme :White Off-White Slightly Yellow PowderMasse moléculaire :767.54 g/molN-Pyrrolo-2'-deoxycytidine
CAS :<p>N-Pyrrolo-2'-deoxycytidine is a nucleoside analog that is used in the laboratory as a template for DNA synthesis. It has been shown to be an effective inhibitor of human pathogens. N-Pyrrolo-2'-deoxycytidine binds to DNA and prevents replication by interfering with the binding of the enzyme polymerase to the template strand, which leads to denaturation of the complementary strand and blocking of DNA elongation. This drug has been shown to bind specifically to sequences that are unpaired in duplexes, such as single-stranded telomeres. N-Pyrrolo-2'-deoxycytidine can also be used as a fluorescence probe for detecting dsDNA duplexes.</p>Formule :C12H15N3O4Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :265.27 g/mol2'-Deoxy-2-methoxyadenosine
CAS :<p>2'-Deoxy-2-methoxyadenosine is a nucleoside that has been isolated from the sponge Spongospora. It is a glycosylated nucleoside that contains a formamidine chromophore and an amino function. The molecule has been synthesized by solid-phase synthesis, which involves the use of phosphoramidite chemistry to attach a series of building blocks onto an oligonucleotide template. 2'-Deoxy-2-methoxyadenosine was found to have thermal stability in phosphate buffer solutions and low reactivity with nucleophiles such as ammonia or methylamine. This nucleoside can be used as a substituent in synthetic organic chemistry and has been shown to inhibit the growth of bacteria such as Clostridium perfringens.</p>Formule :C11H15N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :281.27 g/mol2',3'-Dideoxy-5'-O-DMT-uridine
CAS :<p>2',3'-Dideoxy-5'-O-DMT-uridine is a nucleoside for use in research applications</p>Formule :C30H30N4O6Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :514.58 g/mol
