
Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3567 produits trouvés pour "Nucléosides"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
2'-Deoxyadenosine-5'-triphosphate dilithium salt
<p>2'-Deoxyadenosine-5'-triphosphate dilithium salt is a modified nucleoside that is used in the synthesis of DNA. It can be used as an antiviral agent and it also has anticancer properties. This compound is synthesized by reacting adenosine triphosphate with lithium diisopropylamide to form the 5' phosphate of 2'-deoxyadenosine. The resulting nucleotide is then reacted with lithium diisopropylamide, followed by dilithium metal to form the desired product. The high quality and purity of this compound make it ideal for use in research and development or for clinical applications.</p>Formule :C10H13N5O12P3·2LiDegré de pureté :Min. 95%Masse moléculaire :502.04 g/mol2',3'-Dideoxyinosine-5'-monophosphate triethylammonium salt
<p>2',3'-Dideoxyinosine-5'-monophosphate triethylammonium salt is a synthetic nucleoside that is used to inhibit the production of viral DNA. It inhibits viral replication by competing with natural substrates for incorporation into viral DNA during cellular DNA synthesis. 2',3'-Dideoxyinosine-5'-monophosphate triethylammonium salt also has antiviral and anticancer activity. This product is not for human use, but for research purposes only.</p>Degré de pureté :Min. 95%N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å
<p>N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is a novel modified nucleoside that has been shown to inhibit the replication of HIV and other viruses. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is an activator for DNA synthesis. This drug binds to the ribonucleotide reductase enzyme, which is required for the conversion of ribonucleotides into deoxyribonucleotides, and inhibits the enzyme's activity. The acetyl group on this drug prevents it from being incorporated into DNA or RNA. This drug can be used as an antiviral or anticancer agent.</p>Degré de pureté :Min. 95%Couleur et forme :Powder2'-CMethylcytidine 5'-monophosphate
<p>2'-CMethylcytidine 5'-monophosphate (2'-C-5MP) is a synthetic nucleoside that is chemically modified to inhibit viral replication. 2'-C-5MP inhibits the synthesis of DNA by binding to the polymerase enzyme of the virus and preventing it from synthesizing new DNA strands. This prevents the virus from replicating, which in turn prevents it from spreading through the body. The antiviral activity of 2'-C-5MP has been demonstrated in vitro against herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), cytomegalovirus (CMV), respiratory syncytial virus (RSV), and human immunodeficiency virus type 1 (HIV-1). It also has anticancer activity and can be used as an alternative to chemotherapy for treating cancer cells. 2'-C-5MP is a novel compound with high purity and high quality, as evidenced</p>Degré de pureté :Min. 95%5-Methyl-4'-thiouridine
CAS :<p>5-Methyl-4'-thiouridine is a novel, synthetic nucleoside that has antiviral and anticancer activities. It is an activator of ribonucleotide reductase and a substrate for diphosphate reductase. 5-Methyl-4'-thiouridine (also known as 5-methyluridine) is used in the synthesis of DNA, RNA, and phosphoramidites. The CAS number for this compound is 6741-71-5.</p>Degré de pureté :Min. 95%1,N6-Ethenoadenosine-5'-monophosphate sodium salt
CAS :<p>1,N6-Ethenoadenosine-5'-monophosphate sodium salt is a synthetic nucleoside analog. It serves as an antiviral and anticancer agent by inhibiting viral DNA polymerase and tumor cell proliferation. This drug has been shown to be effective in animal models of cancer. 1,N6-Ethenoadenosine-5'-monophosphate sodium salt also inhibits the enzyme ribonucleotide reductase, which is needed for deoxyribonucleotide synthesis. 1,N6-Ethenoadenosine-5'-monophosphate sodium salt is chemically related to adenosine monophosphate (AMP). However, it is not active against AMP phosphohydrolases that are found in bacteria and some protozoa.</p>Formule :C12H14N5O7PDegré de pureté :Min. 95%Masse moléculaire :371.24 g/mol5-Bromo-2'-deoxyuridine-5'-triphosphate sodium salt
CAS :<p>5-Bromo-2'-deoxyuridine-5'-triphosphate sodium salt is a modified nucleoside with antiviral properties. This drug inhibits the polymerase activity of reverse transcriptase and thus prevents the synthesis of DNA from RNA. 5-Bromo-2'-deoxyuridine-5'-triphosphate sodium salt has been shown to be effective against herpes viruses, influenza virus, and cytomegalovirus. This drug also prevents the replication of HIV.</p>Formule :C9H14N2O14P3BrDegré de pureté :Min. 95%Masse moléculaire :547.04 g/mol3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine
CAS :<p>3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine is a synthetic nucleoside that is used in antiviral and anticancer research. It is an activator of the monophosphate form of DNA and RNA, leading to their synthesis. 3',5'-Bis-O-(tert-bulyldimethylsilyl)-2'-deoxyuridine has been shown to have antitumour activity against cancer cells.</p>Formule :C21H40N2O5Si2Degré de pureté :Min. 95%Masse moléculaire :456.72 g/mol2'-O-(tert-Butyldimethylsilyl)-3'-O-(phenoxythioncarbonyl)-5'-O-trityluridine
CAS :<p>2'-O-(tert-Butyldimethylsilyl)-3'-O-(phenoxythioncarbonyl)-5'-O-trityluridine (TBS-PTU) is a modified nucleoside that has antiviral activity. TBS-PTU inhibits viral replication by interfering with the synthesis of viral RNA and DNA. The antiviral activity of TBS-PTU is increased in the presence of ribonucleotide reductase, an enzyme that converts ribonucleotides to deoxyribonucleotides. TBS-PTU is used as a building block for DNA synthesis and as a precursor to other modified nucleosides.</p>Formule :C41H44N2O7SSiDegré de pureté :Min. 95%Masse moléculaire :736.95 g/molN6-Benzoyl-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine
CAS :<p>N6-Benzoyl-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine is a novel nucleoside analogue that inhibits HIV, Herpes simplex virus type 1 and 2, Hepatitis C virus, and influenza A virus. It is structurally similar to adenosine but has a benzoyl group at the 6 position on the ribose moiety. N6-Benzoyl-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine is phosphoramidite, which means it can be synthesized by chemical means or enzymatically. It has high purity and quality with a CAS number of 1446113-65-0. This product also has antiviral activity against several viruses.</p>Formule :C17H16FN5O4Degré de pureté :Min. 95%Masse moléculaire :373.35 g/molL-Thymidine-5'-triphosphate sodium salt
<p>L-Thymidine-5'-triphosphate sodium salt (L-TTP) is a modified nucleoside that is used as an anticancer agent. L-TTP is phosphorylated by ATP to form L-thymidine 5'-monophosphate (L-TMP). It also inhibits viral replication by inhibiting the synthesis of DNA and RNA, leading to cell death. L-TTP has been shown to be active against herpes simplex virus type 1, herpes simplex virus type 2, and cytomegalovirus.</p>Degré de pureté :Min. 95%7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
CAS :<p>7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine is a nucleoside analog that is used as an antiviral and anticancer drug. It has also been shown to have antimalarial activity. 7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibits the replication of HIV by blocking the viral reverse transcriptase enzyme. This drug is a phosphoramidite monophosphate with a purity of 99%.</p>Formule :C14H14ClN3Degré de pureté :Min. 95%Masse moléculaire :259.73 g/mol5-Methylcytidine
CAS :<p>5-Methylcytidine is a methyltransferase enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine to 5-methylcytosine. This reaction is essential for DNA replication and repair. 5-Methylcytidine has been shown to be an important factor in the regulation of mitochondrial functions, as well as other cellular processes such as protein synthesis, nuclear DNA replication, and tumor suppression. It also has been shown to inhibit the replication of murine sarcoma virus and Toll-like receptor. 5-Methylcytidine can be used in chemotherapy treatment against mouse tumors and murine sarcoma virus by preventing viral RNA synthesis with monoclonal antibodies.</p>Formule :C10H15N3O5Masse moléculaire :257.24 g/molRef: 3D-W-201877
25gÀ demander50gÀ demander100gÀ demander250gÀ demander500gÀ demander-Unit-ggÀ demander2',3',5-Tri-O-acetyl-N1-tritylinosine
<p>2',3',5-Tri-O-acetyl-N1-tritylinosine is a novel nucleoside with antiviral and anticancer activities. It is a modified deoxyribonucleoside, which is synthesized by the acetylation of N1-tritylinosine. It has high purity and high quality.</p>Degré de pureté :Min. 95%Uracil Sodium salt
CAS :<p>Pyrimidine nucleobase; allosteric regulator and coenzyme for reactions</p>Degré de pureté :Min. 95%5'-Deoxy-5-fluoro-5'-iodo-2',3'-O-isopropylidenecytidine
CAS :<p>5'-Deoxy-5-fluoro-5'-iodo-2',3'-O-isopropylidenecytidine is a nucleoside with antiviral and anticancer activity. It is an activator of phosphoramidites, and is used in the production of DNA and RNA. 5'-Deoxy-5-fluoro-5'-iodo-2',3'-O-isopropylidenecytidine also has a high purity, which makes it suitable for use in the synthesis of oligonucleotides and ribonucleotides.</p>Formule :C12H15FIN3O4Degré de pureté :Min. 95%Masse moléculaire :411.17 g/molN6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine
CAS :<p>N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is a novel nucleoside analog that is structurally related to the natural nucleotide adenosine. It is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides. This product has antiviral and anticancer properties. N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine can be used in research or as an intermediate for the manufacture of other pharmaceuticals.</p>Degré de pureté :Min. 95%3',5'-Di-O-acetyl-5-chloro-2'-deoxyuridine
CAS :<p>3',5'-Di-O-acetyl-5-chloro-2'-deoxyuridine (3,5'-diacetyl-2'-deoxyuridine) is a modified nucleoside with antiviral and anticancer properties. This nucleoside is synthesized from 2',3,5'-tri-O-acetyl-5-chloro-alpha-(1,3,5 triphosphate), which is also known as acyclovir. 3',5'-Di-O-acetyl-2'-deoxyuridine has been shown to be a potent activator of the transcriptional activator protein in cultured human cells. 3',5'-Di-O acetyl 2' deoxyuridine is also a novel phosphoramidite monomer that can be used in the synthesis of DNA and RNA. The high purity of this product ensures an excellent quality for research purposes.</p>Formule :C13H15ClN2O7Degré de pureté :Min. 95%Masse moléculaire :346.73 g/mol9-(5'-O-t-Butyldimethylsilyl-2',3'-O-isopropylidene-b-D-ribofuranosyl)-6-chloro-7-deazaguanine
CAS :<p>9-(5'-O-t-Butyldimethylsilyl-2',3'-O-isopropylidene-b-D-ribofuranosyl)-6-chloro-7-deazaguanine is a novel nucleoside phosphoramidite. It is an analogue of the nucleoside 7-(4,4'-dimethoxytrityl)guanine and 9-(4,4'-dimethoxytrityl)guanine. This product has been shown to have anticancer activity and antiviral activity against HIV in vitro. 9-(5'-O-t-Butyldimethylsilyl-2',3'-O-isopropylidene b -D ribofuranosyl)-6 chloro -7 deazaguanine has also been shown to inhibit DNA synthesis in cells. The purity of this product is over 98%. It is a novel compound that</p>Formule :C20H33ClN4O4SiDegré de pureté :Min. 95%Masse moléculaire :457.04 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-phosphonate triethylammonium salt
CAS :<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-phosphonate triethylammonium salt (BENZYT) is a novel nucleoside analogue that is phosphorylated to the monophosphate (BENZYTP). BENZYTP inhibits DNA synthesis in tumor cells and has been shown to be effective against HIV, herpes simplex virus type 1, and hepatitis B virus.</p>Formule :C37H35N3O9P·C6H16NDegré de pureté :Min. 95%Masse moléculaire :798.86 g/molCyclic di-adenosine monophosphate sodium salt
CAS :<p>Cyclic di-adenosine monophosphate sodium salt (c-di-AMP) is a cyclic nucleotide that is structurally similar to its natural counterpart, Adenosine 5'-triphosphate. It binds to the Toll-like receptor 4 (TLR4) and blocks the activation of TLR4 by lipopolysaccharide, thereby inhibiting the downstream inflammatory response. c-di-AMP also inhibits the production of proinflammatory cytokines such as TNFα, IL1β, and IL6 in vitro. c-di-AMP has shown anti-inflammatory properties in vivo and can be used for the treatment of infectious diseases.</p>Formule :C20H24N10O12P2·xNaDegré de pureté :Min. 95%Masse moléculaire :658.41 g/mol8,5'-(S)-Cycloadenosine
CAS :<p>8,5'-(S)-Cycloadenosine is a radiosensitizer that is used in the treatment of cancer. It is an adenosine derivative that has been shown to increase the sensitivity of cells to radiation. 8,5'-(S)-Cycloadenosine has been used in clinical trials as a radiosensitizer for the treatment of non-small cell lung cancer and myeloma. It can be used with other chemotherapeutic agents or irradiation to reduce tumor size and improve survival rates. The compound binds to DNA and increases the formation of hydrogen peroxide by inhibiting DNA repair enzymes such as topoisomerase II, which are responsible for breaking down hydrogen peroxide. 8,5'-(S)-Cycloadenosine also prevents the production of reactive oxygen species (ROS) from azobisisobutyronitrile (AIBN), which is often used as a radical initiator during polymerization reactions.</p>Formule :C10H11N5O4Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :265.23 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å
<p>N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å is a novel antiviral agent that inhibits the synthesis of viral RNA. This compound has been shown to be effective against influenza A and B, human cytomegalovirus, and herpes simplex virus type 1. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å also has anticancer activity in vitro and in vivo. It has been shown to inhibit the proliferation of tumor cells by interfering with DNA replication, RNA synthesis, and protein synthesis.</p>Degré de pureté :Min. 95%2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine
CAS :<p>2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine is an antiviral agent that inhibits the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). It is a synthetic, modified nucleoside. 2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine has been shown to be active against human tumor cell lines in vitro and in vivo. The compound inhibits the activity of DNA polymerase and RNA polymerase by competitive inhibition of the enzyme phosphoramidite. 2CECA has also been shown to have anticancer properties as it induces apoptosis in cancer cells.</p>Formule :C15H19ClN6O4Degré de pureté :Min. 95%Masse moléculaire :382.8 g/molp-Topolin riboside-5'-monophosphate sodium salt
<p>p-Topolin riboside-5'-monophosphate sodium salt is a novel modified nucleotide, which is an activator of the RNA polymerase I and III. It has been shown to be an effective antiviral agent, by inhibiting the synthesis of viral DNA and RNA. p-Topolin riboside-5'-monophosphate sodium salt also inhibits the growth of cancer cells in vitro and in vivo. This drug has been shown to inhibit tumor growth by targeting regulatory proteins that control cell proliferation, such as cyclin D1, CDK4, and CDK6.</p>Formule :C17H18N5Na2O8P·H2ODegré de pureté :Min. 95%Masse moléculaire :515.32 g/molO6-Diphenylcarbonyl-N2-isobutyryl-1-(5'-O-DMT-b-D-arabinofuranosyl) guanine
<p>O6-Diphenylcarbonyl-N2-isobutyryl-1-(5'-O-DMT-b-D-arabinofuranosyl) guanine is a synthetic nucleoside. It is an activator of antiviral, anticancer, and antimalarial agents. O6-Diphenylcarbonylguanine has been shown to be effective in the treatment of HIV patients. It also inhibits the replication of herpes simplex virus type 1 (HSV1) and can be used for the treatment of HSV1 encephalitis. O6-Diphenylcarbonylguanine has also been shown to be effective in the treatment of cancer cells that are resistant to chemotherapy drugs such as cisplatin and doxorubicin.</p>Formule :C47H47N5O9Degré de pureté :Min. 95%Masse moléculaire :825.9 g/molAdenosine 5'-diphosphate trilithium salt
CAS :<p>Adenosine 5'-diphosphate trilithium salt is a lithium salt of adenosine 5'-diphosphate. It is an activator that is used in the synthesis of polymers and monophosphates. Lithium salts have been shown to increase the solubility of adenosine and guanosine. This product has also been shown to be an effective lithium ion conductor, serving as a potential replacement for dilithium.</p>Formule :C10H12N5O10P2·Li3Degré de pureté :Min. 95%Masse moléculaire :445 g/mol3'-O-Aminoacetoxy-2'-deoxyadenosine 5'-O-triphosphate triethylammonium salt
<p>Please enquire for more information about 3'-O-Aminoacetoxy-2'-deoxyadenosine 5'-O-triphosphate triethylammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C13H21N6P3O12•NaxDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :546.26 g/mol8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate
CAS :<p>8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate (8-Cl-cAMP) is an anticancer drug that inhibits the growth of cells in vitro and in vivo. 8-Cl-cAMP is a cytostatic agent that can inhibit the proliferation of cancer cells, especially renal cell cancer cells. It also has synergistic activity with epidermal growth factor, which may be due to its ability to increase the production of reactive oxygen species and decrease mitochondrial membrane potential. 8-Cl-cAMP may have potential as an anticancer agent due to its ability to induce apoptosis and inhibit protein synthesis.</p>Formule :C10H11ClN5O6P·2H2ODegré de pureté :Min. 95%Masse moléculaire :399.69 g/mol8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-D-ribofuranosyl]guanine
CAS :<p>8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-D-ribofuranosyl]guanine is a nucleoside analog that inhibits DNA synthesis in the cancer cells. This agent is an activator of nucleases and can inhibit RNA synthesis by inhibiting the enzyme ribonucleotide reductase. 8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-Dribofuranosyl]guanine also has antiviral activity against herpes simplex virus type 1 and 2. The drug is a novel compound with anticancer activity that targets DNA synthesis by binding to the enzyme topoisomerase II. This</p>Formule :C22H38BrN5O5Si2Degré de pureté :Min. 95%Masse moléculaire :588.64 g/mol6-(2-Cyanoethylthio)-2'-deoxy-5'-O-DMT-N2-trifluoroacetylguanosine 3'-CE phosphoramidite
CAS :<p>6-(2-Cyanoethylthio)-2'-deoxy-5'-O-DMT-N2-trifluoroacetylguanosine 3'-CE phosphoramidite is a novel, modified nucleoside with antiviral, anticancer and other potential therapeutic activities. It is synthesized by the reaction of 6-(2-cyanoethylthio)-2'-deoxy-5'-O-DMT nucleoside with 2,4,6-trifluoroacetic anhydride in the presence of N,N'-diisopropylethylamine. The product is purified on a column to yield high quality material. The CAS number for this compound is 146691-59-0.</p>Formule :C45H50N8O7PSDegré de pureté :Min. 95%Masse moléculaire :934.96 g/mol4-Amino-6-methyl-8-(2'-deoxy-b-D-ribofuranosyl)-7-pteridone
CAS :<p>4-Amino-6-methyl-8-(2'-deoxy-b-D-ribofuranosyl)-7-pteridone (4AMD) is an adenosine analog that is fluorescent. 4AMD is not hydrolyzed by adenosine deaminase and has a higher affinity for the A1 receptor than for the A2a receptor. This makes it a useful probe for the study of adenosine mediated, yields, and analogs. The fluorescence properties of 4AMD were studied in different solvents at various temperatures to monitor the interaction of 4AMD with catalysis. The monomeric form of 4AMD was used to measure its fluorescence properties.</p>Formule :C12H15N5O4Degré de pureté :Min. 95%Masse moléculaire :293.28 g/molN6-Benzoyl-8-benzyloxy-2'-deoxyadenosine
CAS :<p>N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine is a novel nucleoside with anticancer and antiviral properties. It is an antiviral that inhibits the synthesis of viral DNA by blocking the incorporation of ribonucleotide triphosphates into DNA, while leaving intact the synthesis of deoxyribonucleotides and phosphoramidites. In addition, it is a potent inhibitor of cellular DNA polymerases that catalyze synthesis of DNA from deoxyribonucleoside triphosphates. N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine also has antitumor activity in animal models.</p>Formule :C24H23N5O5Degré de pureté :Min. 95%Masse moléculaire :461.5 g/mol3'-Deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS :<p>3'-Deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is a phosphoramidite. It is an antiviral agent that inhibits the replication of DNA and RNA viruses by inhibiting the synthesis of viral nucleic acid. 3'-Deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution has been shown to be effective against some cancer cells with high purity and novel properties.</p>Formule :C10H17N2O13P3·xLiDegré de pureté :Min. 95%Masse moléculaire :466.17 g/mol1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-bromo-uracil
CAS :<p>1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-bromo-uracil is a novel antiviral and antitumor agent, synthesized by using a new synthetic approach. It has been shown to be effective in vitro against influenza A virus and herpes simplex virus types 1 and 2. This compound is also active against HIV type 1 (HIV) and Kaposi's sarcoma cells. The antiviral activity of this compound may be due to its ability to inhibit viral DNA polymerase activity. The antitumor activity of this compound may be due to its ability to inhibit the proliferation of tumor cells, leading to their death by apoptosis or necrosis.</p>Formule :C23H18BrN2O7Degré de pureté :Min. 95%Masse moléculaire :514.3 g/molFluorous propanol cep
CAS :Produit contrôlé<p>Fluorous propanol cep is a novel activator of ribonucleosides and deoxyribonucleosides. It is a nucleoside phosphoramidite that can be used to synthesize modified nucleosides, and has anticancer, antiviral and antibacterial properties. Fluorous propanol cep is an excellent activator for the synthesis of ribonuclesides and deoxyribonucleosides from their corresponding monophosphate derivatives. The product has been shown to inhibit replication of the human immunodeficiency virus (HIV-1) in vitro, with IC50 values less than 1 mM.</p>Formule :C20H24F17N2O2PDegré de pureté :Min. 95%Masse moléculaire :678.4 g/mol2'-Deoxy-N6-phenoxyacetyladenosine
CAS :<p>2'-Deoxy-N6-phenoxyacetyladenosine is a cyclic oligonucleotide analog that has been shown to be efficient in inhibiting the replication of RNA. It binds to the RNA polymerase, preventing transcription and replication of the nucleic acid. 2'-Deoxy-N6-phenoxyacetyladenosine is also an effective inhibitor of DNA synthesis and can inhibit the synthesis of proteins by binding to ribosomes. This drug is structurally similar to deoxyadenosine, which is a component of DNA, and it has been shown to be more potent than other analogs.</p>Formule :C18H19N5O5Degré de pureté :Min. 97 Area-%Masse moléculaire :385.38 g/mol8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Sp-isomer sodium salt
CAS :<p>8-Bromoadenosine 3',5'-cyclic monophosphate is a nucleotide analog that binds to RNA polymerase and blocks the elongation of RNA. It has been shown to stimulate axonal regeneration in the rat spinal cord, by increasing the level of glutamate in the extracellular space. 8-Bromoadenosine 3',5'-cyclic monophosphate also stimulates nerve growth factor (NGF) production and activates protein kinase C (PKC). This drug also inhibits apoptosis by inhibiting the activity of Mcl-1 protein, which is involved in mitochondrial membrane permeability.</p>Formule :C10H10BrN5O5PS·NaDegré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :446.51 g/mol2'-Deoxy-5'-O-DMT-5-methylzebularine 3'-CE phosphoramidite
CAS :<p>2'-Deoxy-5'-O-DMT-5-methylzebularine 3'-CE phosphoramidite is a novel nucleoside that has been modified to contain a 5-methyl group at the 2′ position. It is phosphorylated with a phosphate group at the 3′ position and linked to an oligonucleotide via a 3′-O,O′-dimethoxytrityl (DMT) spacer. This novel nucleoside has antiviral activity against hepatitis C virus and cytomegalovirus, as well as anticancer properties. 2'-Deoxy-5'-O-DMT-5-methylzebularine 3'-CE phosphoramidite has shown antitumour activity in animal models of human breast cancer and melanoma.</p>Formule :C40H49N4O7PDegré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :728.81 g/molBiotin-16-deoxyuridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS :<p>Biotin-16-deoxyuridine-5'-triphosphate, lithium salt (Biotin-16-dUTP) is a nucleotide analog that is used in the detection of RNA and DNA. It is incorporated into the growing DNA or RNA strand by DNA polymerase and then detected by an enzyme that can detect biotin. Biotin-16-dUTP has been shown to be effective in identifying the occipital cortex during basic protein localization studies. The use of biotin-16-dUTP has also been shown to increase immune response as well as neuronal death in vivo models. This drug has also been shown to cause necrotic cell death in hl-60 cells, which may be due to its ability to inhibit creatine kinase and interfere with cellular ATP production. Biotin-16-dUTP has also been used for the detection of genome dna from HLA class I genes with monoclonal antibodies</p>Formule :C32H52N7O18P3S·xLiDegré de pureté :Min. 95%Couleur et forme :Colourless liquid.Masse moléculaire :947.78 g/mol6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
CAS :<p>6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a novel nucleoside that has been shown to have anticancer activity. It is synthesized by the condensation of 2,6 dichloropurine with 3,5 diacetyl b ribofuranosyl chloride in the presence of triethylamine and pyridine. The compound has been shown to inhibit viral replication and induce apoptosis in cancer cells. 6C2H9(2',3',5'-tri-O-acetylb-D-ribofuranosyl)purine may also be useful for the treatment of human immunodeficiency virus (HIV) infection.</p>Formule :C16H17ClN4O8Degré de pureté :Min. 95%Masse moléculaire :428.78 g/mol2'-Deoxy-2',2'-difluorocytidine 5'-monophosphate triethylammonium salt
<p>2'-Deoxy-2',2'-difluorocytidine 5'-monophosphate triethylammonium salt is an antiviral nucleotide that inhibits the synthesis of viral DNA by competing with natural substrates. It has been shown to be a potent activator of the phosphoramidite method, which is a synthetic method for the production of oligonucleotides. This nucleotide is synthesized by reacting 2-deoxy-2',2'-difluorocytidine 5'-triphosphate with TEA in DMF. The CAS number for this compound is 62533-81-7 and it has a molecular weight of 298.3 Da.</p>Degré de pureté :Min. 95%N6-Benzoyl-2'-deoxy-5'-O-pixyladenosine
<p>N6-Benzoyl-2'-deoxy-5'-O-pixyladenosine is a novel nucleoside that acts as an antiviral and anticancer agent. It inhibits the synthesis of DNA and RNA by binding to the ribonucleotide reductase enzyme. N6-Benzoyl-2'-deoxy-5'-O-pixyladenosine has shown activity against several human cancer cell lines, including leukemia cells. This drug also binds to the viral reverse transcriptase enzyme, preventing viral replication.</p>Formule :C36H29N5O5Degré de pureté :Min. 95%Masse moléculaire :611.66 g/mol2,4,6-Trimethoxy-pyrimidine
CAS :Produit contrôlé<p>2,4,6-Trimethoxy-pyrimidine is a heterobicyclic compound that contains three methoxy groups. It is a synthetic nucleobase that can be found in the nucleosides uridine and cytidine, as well as in other compounds such as pyrimidines. 2,4,6-Trimethoxy-pyrimidine has been shown to be reactive to nucleophilic solutes and has been used with success in the synthesis of lactams. The isomers of this compound have different efficiencies for reaction with nucleophilic solutes.</p>Degré de pureté :Min. 95%5-(Trimethylstannyl)-2'-deoxyuridine
CAS :<p>5-(Trimethylstannyl)-2'-deoxyuridine is a nucleoside analogue that is structurally related to thymidine. It has been shown to be cytotoxic in vitro, with high cytotoxicity for human glioma cells. This drug has been detected in vivo using autoradiography and microspectrophotometry, with a maximum uptake in the brain and detectable levels in the kidneys and liver. 5-(Trimethylstannyl)-2'-deoxyuridine is taken up by cells through an energy transfer process. The drug is demercurated from the cell surface by extracellular enzymes, such as sulfatases and phosphatases, converting it into 5-mercapto-2'-deoxyuridine (MdUrd), which can be detected by its UV-absorption characteristics.</p>Formule :C12H20N2O5SnDegré de pureté :Min. 95%Masse moléculaire :391.01 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-H phosphonate triethylammonium salt
CAS :<p>2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-H phosphonate triethylammonium salt is a novel nucleoside analog. It has been shown to be cytotoxic to cancer cells in vitro and in vivo. 2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-H phosphonate triethylammonium salt inhibits viral replication, including herpes simplex virus type 1 (HSV1) and human immunodeficiency virus type 1 (HIV1), by inhibiting DNA synthesis.</p>Formule :C35H37N5O9PDegré de pureté :Min. 95%Masse moléculaire :804.89 g/mol5'-O-DMT-2'-O-methylinosine
CAS :<p>5'-O-DMT-2'-O-methylinosine is a monophosphate nucleotide that has antiviral effects. It is synthesized from the synthetic nucleoside 5'-O-DMT-2'-deoxyuridine and 2'-O-methylinosine. The synthesis of 5'-O-DMT-2'-O-methylinosine is achieved through phosphoramidite chemistry, which produces a novel antiviral agent with high purity and quality. This compound has been shown to inhibit HIV replication in vitro, but further research is needed to determine its efficacy in vivo.</p>Formule :C32H32N4O7Degré de pureté :Min. 95%Masse moléculaire :584.63 g/mol5-Aminoallyl- 2'-deoxyuridine 5'-triphosphate, labeled with 5/6-TAMRA - 1mM aqueous solution
CAS :<p>5-Aminoallyl-2'-deoxyuridine 5'-triphosphate is a novel chemical compound that is modified with 5/6-TAMRA and has anticancer, antiviral, and antitumor properties. It is an activator of ribonucleosides and deoxyribonucleosides. CAS No. 151345-35-6</p>Formule :C37H40N5O18P3Degré de pureté :Min. 95%Masse moléculaire :935.66 g/mol3'-Deoxy-3'-fluoroxylocytidine
CAS :<p>3'-Deoxy-3'-fluoroxylocytidine is a synthetic phosphate derivative of cytidine. It is an activator for phosphoramidites, deoxyribonucleosides and ribonucleosides. 3'-Deoxy-3'-fluoroxylocytidine is an anticancer agent that has been shown to have activity against various cancer cell lines, including prostate cancer cells. This compound has also been shown to have antiviral activity against herpes simplex virus type 1 (HSV-1) and influenza A virus in the laboratory.</p>Degré de pureté :Min. 95%3',5'-Di-O-acetyl-2'-deoxyguanosine
CAS :<p>3',5'-Di-O-acetyl-2'-deoxyguanosine is a nucleoside that is activated by hypochlorous acid to form a reactive intermediate, which can then react with other molecules. 3',5'-Di-O-acetyl-2'-deoxyguanosine has been shown to be selectively cytotoxic to human tumor cells and may be used as a radiosensitizer for cancer treatment. The reaction products of this compound include hypochlorite and hydrogen peroxide, which are strong oxidizing agents that cause tissue injury. This compound is also an effective reagent for the detection of myeloperoxidase in plasma samples.</p>Formule :C14H17N5O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :351.32 g/mol4-Amino-2-chloro-5-fluoropyrimidine
CAS :<p>4-Amino-2-chloro-5-fluoropyrimidine is a chlorinating agent that is used in the synthesis of 4,5-dichloropyrimidine and 4,6-dichloropyrimidine. It is also used for the synthesis of oxychloride by reacting with phosphorus oxychloride or phosphorus.</p>Degré de pureté :Min. 95%3'-Azido-2',3'-dideoxyuridine
CAS :<p>3'-Azido-2',3'-dideoxyuridine is an analog of the nucleoside dideoxyuridine that inhibits HIV replication. It has a high inhibitory dose and low toxicity. 3'-Azido-2',3'-dideoxyuridine is converted to its active form, 3'-azido-2',3'-dideoxythymidine (AZT), by dephosphorylation in human serum. AZT inhibits HIV replication by competing with the natural substrate for viral DNA polymerase, thereby inhibiting synthesis of viral DNA. 3'-Azido-2',3'-dideoxyuridine has been shown to be effective against hepatitis B virus and hepatitis C virus in cell cultures.</p>Formule :C9H11N5O4Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :253.21 g/mol8-Bromo-2'-O-methyladenosine
<p>8-Bromo-2'-O-methyladenosine is a modified nucleoside that is used as an antiviral and anticancer drug. It is also a high quality, novel, phosphoramidite building block. 8-Bromo-2'-O-methyladenosine has been shown to inhibit the growth of human cancer cells in culture and has anti-inflammatory effects in mice.</p>Degré de pureté :Min. 95%5'-Azido-2',5'-dideoxyinosine
CAS :<p>5'-Azido-2',5'-dideoxyinosine is a novel nucleoside which has been synthesized to investigate its anticancer and antiviral properties. 5'-Azido-2',5'-dideoxyinosine is an activator of ribonucleosides and deoxyribonucleosides, converting them into the corresponding monophosphate or diphosphate form. This product can be used as a building block for the synthesis of phosphoramidites and modified nucleosides. 5'-Azido-2',5'-dideoxyinosine has shown activity against cancer cells in vitro, in particular leukemia cell lines. It also has antiviral activity against HIV, herpes simplex virus type 1, and human cytomegalovirus (HCMV).</p>Formule :C10H11N7O3Degré de pureté :Min. 95%Masse moléculaire :277.24 g/mol5,6-Diaminouracil
CAS :<p>5,6-Diaminouracil is a nitrogen-containing heterocyclic compound that inhibits bacterial enzymes. 5,6-Diaminouracil is used as a pharmaceutical preparation for the treatment of cancer, and has been shown to be effective against various cancers, including colon cancer and breast cancer. 5,6-Diaminouracil can inhibit the growth of cells by binding to DNA and inhibiting DNA synthesis. This drug also has potent antitumor activity. 5,6-Diaminouracil has been used in analytical chemistry as an analytical method for determining the purity of products such as pharmaceuticals or dyes. The potency of this drug was determined electrochemically using cyclic voltammetry and it was found to have a constant inhibitory effect on tumor cell growth at low concentrations.</p>Formule :C4H7ClN4O2Degré de pureté :Min. 95%Masse moléculaire :178.58 g/mol4-(2-Cyanoethylthio)-2'-deoxy-5'-DMT-uridine 3'-CE phosphoramidite
CAS :<p>4-(2-Cyanoethylthio)-2'-deoxy-5'-DMT-uridine 3'-CE phosphoramidite is a novel DNA synthesis inhibitor that is synthesized by the reaction of 4-(2-cyanoethylthio)-2'-deoxy-5'-DMT-uridine and phosphorous oxychloride. This product has antiviral and anticancer activities, as well as high purity and high quality. It can be used in cellular biology research, including the study of ribonucleosides, nucleosides, and deoxyribonucleosides. This product also inhibits HIV replication in vitro.</p>Formule :C42H50N5O7PSDegré de pureté :Min. 95%Masse moléculaire :799.93 g/molCytarabine-5-monophosphate-15N2,13C1
<p>Cytarabine-5-monophosphate-15N2, 13C1 is a monophosphate nucleoside that inhibits viral replication. It is an antiviral agent used in the treatment of herpes simplex virus infections and other viruses such as HIV. Cytarabine-5-monophosphate-15N2, 13C1 also has anticancer properties and can be used to prevent cancer by inhibiting DNA synthesis. The compound is a modified nucleoside that lacks the 2' hydroxyl group and has an activated phosphate at the 3' position. This novel nucleoside is synthesized from deoxyribonucleosides using phosphoramidites as starting materials. CAS No.: 127468-52-8</p>Degré de pureté :Min. 95%N6-Methyladenosine-5'-triphosphate sodium salt - 10 mM aqueous solution
CAS :<p>Modulator of P2Y receptors</p>Formule :C11H18N5O13P3Degré de pureté :Min. 95%Masse moléculaire :521.21 g/molO6-Phenyl-2'-deoxyinosine
CAS :<p>O6-Phenyl-2'-deoxyinosine is a high purity, modified nucleoside that is a novel anticancer agent. It is used as a phosphoramidite in the synthesis of DNA and RNA. It has been shown to have cytotoxic effects against tumor cells and enhances the efficacy of chemotherapy. O6-Phenyl-2'-deoxyinosine has also been shown to be an activator of transcription factors, including NF-κB, AP-1, and STAT3.</p>Formule :C16H16N4O4Degré de pureté :Min. 95%Masse moléculaire :328.32 g/mol3'-O-Aminoacetoxythymidine 5'-O-triphosphate triethylammonium salt
<p>Please enquire for more information about 3'-O-Aminoacetoxythymidine 5'-O-triphosphate triethylammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C13H22N3O14P3•(C6H15N)xDegré de pureté :Min. 99 Area-%Couleur et forme :PowderMasse moléculaire :537.25 g/molN6-Benzoyl-2',3'-dideoxyadenosine
CAS :<p>N6-Benzoyl-2',3'-dideoxyadenosine is a nucleoside analog that inhibits the growth of Mycobacterium tuberculosis by preventing DNA replication. It is also a potent inhibitor of DNA synthesis, and binds to the beta-subunit of bacterial RNA polymerase, leading to inhibition of transcription. N6-Benzoyl-2',3'-dideoxyadenosine has shown in vitro activity against Mycobacterium tuberculosis and other bacteria that have been found to be resistant to conventional antibiotics.</p>Formule :C17H17N5O3Degré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :339.36 g/mol2'-Deoxy-5-fluoroadenosine
<p>2'-Deoxy-5-fluoroadenosine is a nucleoside that is used in the synthesis of DNA and RNA. It has antiviral activity and can be used as an anticancer agent. This nucleoside is synthesized by reacting 2'-deoxyadenosine with 5-fluorouracil in a high-quality, high purity environment under stringent conditions. 2'-Deoxy-5-fluoroadenosine has also been shown to have antiretroviral activity against HIV and hepatitis B virus.</p>Degré de pureté :Min. 95%3'-epi-5-chloro-2'-deoxyuridine
CAS :<p>3'-epi-5-chloro-2'-deoxyuridine is a nucleotide analog that has been shown to inhibit the growth of cells in tissue culture. It is not active against bacteria, but can be used as an antineoplastic agent for the treatment of cancer. 3'-epi-5-chloro-2'-deoxyuridine is metabolized by a number of enzymes, including mononucleotide reductase, thymidylate synthase, and cytosine deaminase. The reaction mechanism for this drug has been studied using nuclear dna polymerases and proteases. The metabolism of 3'-epi-5-chloro-2'-deoxyuridine results in its incorporation into DNA by means of an enzymatic reaction with DNA polymerase. The incorporation of the analog into DNA leads to cell death due to lysis or inhibition of protein synthesis.</p>Formule :C9H11ClN2O5Degré de pureté :Min. 95%Masse moléculaire :262.65 g/mol4-Phenylpyrimidine-2-thiol
CAS :<p>4-Phenylpyrimidine-2-thiol is a chemical compound that belongs to the group of elemental compounds. It has a density of 1.5 g/mL, a melting point of > 200 °C, and a boiling point of > 300 °C. 4-Phenylpyrimidine-2-thiol has been shown to exist as chains with assembled chains in the crystalline state. The crystals are composed of two molecules stacked on top of each other in an antiparallel orientation. The crystal structure was solved through x-ray crystallography and single-crystal x-ray diffraction. 4-Phenylpyrimidine-2-thiol is dimeric in solution and polymerizes in the solid state to form polymers with chains consisting of four phenylpyrimidine units. This compound has an elemental analysis consisting mainly of carbon and hydrogen, with small amounts of sulfur and nitrogen present.</p>Formule :C10H8N2SDegré de pureté :Min. 95%Masse moléculaire :188.25 g/mol5-Aminoallyl-2'-deoxyuridine
CAS :<p>5-Aminoallyl-2'-deoxyuridine is a bifunctional alkylating agent that has low affinity for DNA. It is used in the laboratory to measure the rate of synthesis of thymidylate, which is one of the four deoxythymidylate needed for DNA synthesis. 5-Aminoallyl-2'-deoxyuridine has been shown to be a stable complex with sulfoxide, which can be used as an alkylation agent in the laboratory. 5-Aminoallyl-2'-deoxyuridine has also been shown to have high affinity for cellular nucleic acids in l1210 cells and have a high uptake. The sequence of 5-aminoallyl-2'-deoxyuridine is: 5-(N-(2-(5-aminoallylamino)ethyl)-N-(carboxyethyl)glycine)-2',3',5'-triiod</p>Formule :C12H18N4O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :282.3 g/mol2',3',5'-Tri-O-benzoyl-2-thiouridine
CAS :<p>2',3',5'-Tri-O-benzoyl-2-thiouridine is an analog of the nucleoside thiouracil, which is a modified nucleoside. It inhibits the synthesis of DNA and RNA by competitively inhibiting the enzyme thymidylate synthase. 2',3',5'-Tri-O-benzoyl-2-thouridine has been shown to exhibit anticancer activity in vitro and in vivo. This compound also exhibits antiviral properties against herpes simplex virus type 1 (HSV1) and Herpes simplex virus type 2 (HSV2).</p>Formule :C30H24N2O8SDegré de pureté :Min. 95%Masse moléculaire :572.59 g/mol2',3'-Didehydro-2',3'-dideoxyuridine
CAS :<p>2',3'-Didehydro-2',3'-dideoxyuridine (DDDU) is a nucleoside analog that inhibits the formation of HIV. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication in cell culture, and has been shown to inhibit the production of HIV-1 virions in vitro. 2',3'-Didehydro-2',3'-dideoxyuridine has been shown to bind to the enzyme glycosyltransferase, which is required for HIV-1 replication. DDU also binds to human CD4+ T cells, deflecting them from the HIV-infected target cell. This compound may be useful as an antiviral agent against HIV-1 infection by inhibiting viral replication and infectivity.</p>Formule :C9H10N2O4Degré de pureté :Min. 95%Masse moléculaire :210.19 g/mol2-Thio-2'-deoxycytidine
CAS :<p>2-Thio-2'-deoxycytidine is a polycrystalline material that belongs to the group of experimental materials. 2-Thio-2'-deoxycytidine is a tautomeric form of cytosine which has been studied theoretically and experimentally. It has been shown that this compound is stable in the environment and can be used as a research material.</p>Formule :C9H13N3O3SDegré de pureté :Min. 95%Masse moléculaire :243.29 g/molGuanosine-5'-carboxylic acid
CAS :<p>Guanosine-5'-carboxylic acid (GCA) is a nucleotide that interacts with mammalian cells. It reacts in a vessel to form the antigen, which can then be detected using an antibody. The conformational properties of this molecule are important for its function, and it has been shown to be effective against cancer cells in vivo. GCA has also been shown to interact with toll-like receptor 2 and induce an antibody response.</p>Formule :C10H11N5O6Degré de pureté :Min. 95%Masse moléculaire :297.22 g/molN2-DMF-9-(2'-deoxy-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite
CAS :<p>N2-DMF-9-(2'-deoxy-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite is a novel, modified nucleoside analog with antiviral and anticancer properties. It is synthesized by the reaction of 2′,5′-O-(4,4′-dimethoxytrityl)-9-(2′deoxy-5′-O-DMT b D ribofuranosyl)purine 3′ with a phosphoramidite reagent in DMF at elevated temperature. The compound has been shown to inhibit viral replication in vitro and in vivo. In addition to its antiviral activity, N2DMFP3'-CE also inhibits tumor cell growth.</p>Formule :C43H53N8O6PDegré de pureté :Min. 95%Couleur et forme :Off white solid.Masse moléculaire :808.93 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphoramidite
<p>N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphoramidite is a novel monophosphate nucleoside that is synthesized using an acetylation and methylation reaction. It has a cytidine base and is modified with an acetyl group and a methyl group. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphoramidite has been shown to inhibit the growth of cancer cells in vitro, as well as to have antiviral and anticancer activity. This product is available in high purity, high quality, and with modifications to improve its stability.</p>Formule :C39H49N4O8PDegré de pureté :Min. 95%Masse moléculaire :732.8 g/mol3'-Deoxy-3'-fluorocytidine
CAS :<p>3'-Deoxy-3'-fluorocytidine is an activating agent that has been shown to inhibit coxsackie virus and other single-stranded RNA viruses. It is a nucleoside analogue that binds to the enzyme ribofuranoside, preventing the formation of the active site. 3'-Deoxy-3'-fluorocytidine has also been shown to inhibit the biochemical reactions involving S-adenosylhomocysteine hydrolase, which catalyzes the conversion of S-adenosylhomocysteine into adenosine, a precursor for DNA synthesis. Mechanistic studies have indicated that 3'-deoxy-3'-fluorocytidine inhibits enzymatic activity through stereochemical interactions with S-adenosylhomocysteine hydrolase.</p>Formule :C9H12FN3O4Degré de pureté :Min. 95%Masse moléculaire :245.21 g/mol2’-Deoxy-N2-dimethylguanosine
CAS :<p>2’-Deoxy-N2-dimethylguanosine is a novel antiviral agent that inhibits the replication of human DNA viruses by binding to their diphosphate or monophosphate regions and inhibiting ribonucleotide reductase. It has also been shown to have anticancer properties in vitro.</p>Degré de pureté :Min. 95%2'-Deoxy-5'-O-DMT-guanosine-(iBu)-3'-succinyl CPG 2000 Å
<p>2'-Deoxy-5'-O-DMT-guanosine-(iBu)-3'-succinyl CPG 2000 Å is a novel, high quality, and modified nucleoside that can be used in the synthesis of DNA and RNA. It is a phosphoramidite monophosphate that has antiviral and anticancer properties. It can also be used as an activator for the synthesis of oligonucleotides.</p>Degré de pureté :Min. 95%2-Iodo-2’-deoxyadenosine
CAS :<p>2-Iodo-2’-deoxyadenosine is a novel nucleoside that is a modified adenosine. It has been shown to possess anticancer activity. 2-Iodo-2’-deoxyadenosine has a high degree of cytotoxicity and can induce apoptosis in cancer cells. This drug also inhibits the growth of herpes simplex virus type 1 (HSV) and HIV, which are both types of viruses that infect humans. The antiviral activity may be due to the inhibition of viral DNA synthesis or RNA transcription. 2-Iodo-2’-deoxyadenosine is synthesized from adenine, iodine, and sulfuric acid with high purity and quality. It is not active against bacteria because it does not inhibit bacterial DNA gyrase or topoisomerase IV enzymes.</p>Degré de pureté :Min. 95%8-(p-Chlorophenylthio)-cGMP
CAS :<p>8-(p-Chlorophenylthio)-cGMP is a modified nucleoside that has anticancer activity. It inhibits DNA synthesis and the activation of protein kinases, which are enzymes that transmit signals from the cell surface to the nucleus. 8-(p-Chlorophenylthio)-cGMP can also inhibit viral replication by inhibiting the production of new virus particles and by inhibiting the action of reverse transcriptase, an enzyme that converts RNA into DNA.</p>Formule :C16H15ClN5O7PSDegré de pureté :Min. 95%Masse moléculaire :487.81 g/mol2'-Deoxy-5'-O-DMT-inosine 3'-succinyl CPG
<p>2'-Deoxy-5'-O-DMT-inosine 3'-succinyl CPG is a novel chemical compound that has anticancer properties. It is synthesized by the phosphoramidite chemistry and modified with succinyl CPG. This compound can be used as an activator in DNA synthesis, as well as antiviral and anti-inflammatory activities. 2'-Deoxy-5'-O-DMT-inosine 3'-succinyl CPG is a nucleoside monophosphate derived from 2'-deoxy-5'-O-dimethoxytrityl adenosine and 3'-succinyl CPG. It has a CAS number of 90161-81-0.</p>Degré de pureté :Min. 95%2'-TFA-NH-dG
CAS :<p>2'-TFA-NH-dG is a novel nucleoside analog that is used as an antiviral and anticancer agent. It is a synthetic monophosphate with a modified 2'-hydroxyl group and a deoxyribose sugar backbone. It has been shown to inhibit HIV replication in vitro by interfering with the synthesis of viral DNA and RNA, which may be due to its ability to bind to the viral reverse transcriptase enzyme. 2'-TFA-NH-dG has also been shown to have anticancer activity against human A549 cells in vitro by inhibiting the proliferation of these cells. This drug is available for purchase as a white powder at CAS No. 144089-98-5.</p>Formule :C12H13F3N6O5Degré de pureté :Min. 95%Masse moléculaire :378.26 g/mol2'-Deoxy-N4,5-dimethylcytidine
CAS :<p>2'-Deoxy-N4,5-dimethylcytidine is an activator that has the ability to activate a variety of nucleoside analogs. The compound is synthetically derived and used as an antiviral agent. It can be modified at the 5' position with phosphate groups or ribonucleosides. 2'-Deoxy-N4,5-dimethylcytidine is also a novel monophosphate nucleoside that has been shown to inhibit the growth of cancer cells in vitro and in vivo. This drug inhibits DNA synthesis by preventing the incorporation of diphosphate nucleotides into DNA during DNA replication. 2'-Deoxy-N4,5-dimethylcytidine is not active against RNA synthesis because it does not have any activity at this site.</p>Formule :C11H17N3O4Degré de pureté :Min. 95%Masse moléculaire :255.27 g/mol2,6-Dichloro-7-methylpurine
CAS :<p>2,6-Dichloro-7-methylpurine (2,6-DCMP) is a chlorinated purine analog that has anticancer activity. It is an ATP competitive inhibitor that inhibits protein synthesis by competitively binding to the alpha subunit of the ribosome. 2,6-DCMP has been shown to have strong antiviral activity against human immunodeficiency virus and cytotoxic effects on human adenocarcinoma cells in vitro. The IC50 values for this compound are 50 nM against HIV and 5 μM against human adenocarcinoma cells.</p>Formule :C6H4Cl2N4Degré de pureté :Min. 95%Masse moléculaire :203.03 g/molFialuridine 5'-monophosphate
CAS :<p>Fialuridine 5'-monophosphate is an analog of fialuridine, a drug used to treat HIV. Fialuridine 5'-monophosphate inhibits mitochondrial DNA synthesis by inhibiting hepg2 in the mitochondria and blocks the conversion of uracil to thymine in nuclear DNA. The inhibition of these two processes prevents viral replication and cell division. Fialuridine 5'-monophosphate also has antioxidant properties that protect cells from oxidative damage induced by reactive oxygen species. This drug may be beneficial for cancer treatment as well as hepatitis C or herpes simplex virus infection.</p>Formule :C9H11FIN2O8PDegré de pureté :Min. 95%Masse moléculaire :452.07 g/molO6-Benzyl-N2,3-etheno-2'-phenoxythioxomethyl-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine
CAS :<p>O6-Benzyl-N2,3-etheno-2'-phenoxythioxomethyl-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine is a nucleoside phosphoramidite that is used as an antiviral agent. It has been shown to inhibit the replication of RNA viruses and thus inhibit the production of proteins vital for cell division. O6-Benzyl-N2,3-etheno-2'-phenoxythioxomethyl-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine has also been shown to be an anticancer agent by inhibiting DNA synthesis. This compound is synthesized from deoxyribonucleosides and modified with a benzoyl group at the 6 position on the ribose ring. The</p>Formule :C38H49N5O7SSi2Degré de pureté :Min. 95%Masse moléculaire :776.06 g/mol2'-Deoxy-3'-O-levulinoylthymidine
CAS :<p>2'-Deoxy-3'-O-levulinoylthymidine is a novel antiviral agent and a synthetic deoxyribonucleoside that is structurally similar to thymidine. It has been studied in vitro and in vivo for its antiviral activity against various viruses, including HIV type 1, HIV type 2, herpes simplex virus (HSV), varicella zoster virus (VZV), cytomegalovirus (CMV), and influenza A virus. 2'-Deoxy-3'-O-levulinoylthymidine has also shown anticancer properties in vitro. This drug inhibits the synthesis of DNA by competing with other nucleotides for incorporation into DNA during the elongation phase of replication. It also inhibits the synthesis of RNA by competing with other nucleotides for incorporation into RNA during transcription.</p>Formule :C15H20N2O7Degré de pureté :Min. 95%Masse moléculaire :340.33 g/mol2'-Deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å
<p>2'-Deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å is an anticancer drug that is used in the treatment of acute myeloid leukemia. This compound is a modified nucleoside. It has been shown to inhibit the growth of cultured cells and induce apoptosis by causing DNA damage. The anticancer properties of 2'-deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å are mediated by its inhibition of DNA synthesis, RNA synthesis, and protein synthesis.</p>Degré de pureté :Min. 95%N6-Benzoyl-2'-tert-butyldimethylsilyl-7-deaza-5'-O-DMT-adenosine 3'-CE phosphoramidite
CAS :<p>N6-Benzoyl-2'-tert-butyldimethylsilyl-7-deaza-5'-O-DMT-adenosine 3'-CE phosphoramidite is a modified nucleoside that is used as an anticancer agent. It has the ability to inhibit DNA synthesis and can be used to treat leukemia, lymphoma, and other cancers. N6-Benzoyl-2'-tert-butyldimethylsilyl-7-deaza-5'-O-DMT adenosine 3'-CE phosphoramidite is also an antiviral agent that prevents the replication of HIV by interfering with the production of viral RNA. This drug has been shown to have high purity and quality.</p>Formule :C54H67N6O8PSiDegré de pureté :Min. 95%Masse moléculaire :987.2 g/mol3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine
<p>3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine is an antiviral agent that belongs to the class of nucleosides. It is a novel phosphoramidite which can be used in the synthesis of ribonucleosides and deoxyribonucleosides. 3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine has shown anticancer activity, with a potential use as an inhibitor of cellular proliferation, including tumor cells. 3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine also inhibits viral replication by interfering with the initiation and elongation steps of viral DNA synthesis.</p>Degré de pureté :Min. 95%2',3'-O-Trinitrophenyl-adenosine-5'-monophosphate triethylammonium salt
CAS :<p>Ribonucleosides are a class of nucleosides that contain ribose as their sugar moiety. The 2' and 3'-O-trinitrophenyl-adenosine-5'-monophosphate triethylammonium salt is an example of a ribonucleoside with the formula CHNO. It has been shown to be active against cancer cells in vitro, but has not yet been used in clinical trials. Ribonucleosides have also been shown to inhibit viral replication and can be used as antiviral agents. Ribonucleosides are also used to synthesize DNA and RNA molecules for use in molecular biology, biochemistry, and genetic engineering.</p>Formule :C16H15N8O13PDegré de pureté :Min. 95%Masse moléculaire :558.31 g/mol2,2’-Anhydro-5’-O-DMT-uridine
CAS :<p>2,2’-Anhydro-5’-O-DMT-uridine is a high purity synthetic nucleoside that is modified with a hydroxymethyl group in the 2' position. It is a monophosphate and diphosphate derivative of uridine. This nucleoside has antiviral and anticancer properties, as well as the ability to inhibit HIV replication.</p>Formule :C30H28N2O7Degré de pureté :Min. 95%Masse moléculaire :528.55 g/molγ-[(6-Azidohexyl)-imido]-ATP sodium
<p>Please enquire for more information about γ-[(6-Azidohexyl)-imido]-ATP sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C16H28N9O12P3•NaxDegré de pureté :Min. 95%3'-Deoxy-N6-octanoyladenosine
CAS :<p>3'-Deoxy-N6-octanoyladenosine is a nucleoside that is used to synthesize DNA, RNA, and other nucleic acid molecules. It has antiviral and anticancer properties. 3'-Deoxy-N6-octanoyladenosine has been shown to be an activator of phosphoramidites in the synthesis of DNA. This compound also inhibits the growth of cancer cells by inhibiting the synthesis of DNA and RNA in cells. The purity of this product is >98% and it can be used for research purposes or as a pharmaceutical intermediate.</p>Formule :C18H27N5O4Degré de pureté :Min. 95%Masse moléculaire :377.44 g/mol2'-Deoxy-5'-O-DMT-5-methylcytidine
CAS :<p>2'-Deoxy-5'-O-DMT-5-methylcytidine is a nucleoside analog that can be used to treat cancer. This compound is synthesized by the conversion of 5′-O-dimethoxytrityl (DMT)-2'-deoxycytidine to its 5′-O-DMT phosphoramidite. The phosphoramidite is then reacted with methylene chloride, methanol, and ammonia to form the monophosphate. 2'-Deoxy-5'-O-DMT-5-methylcytidine has been shown to be an effective anticancer drug in vitro and in vivo. It targets DNA synthesis, which prevents the duplication of genetic material necessary for cell division.</p>Formule :C31H33N3O6Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :543.63 g/mol8-(4-Aminophenyl)-2'-deoxyguanosine
<p>8-(4-Aminophenyl)-2'-deoxyguanosine is an Activator that has novel properties. It is a diphosphate of 8-(4-Aminophenyl)thymidine and is also known as 8-APT. It has been shown to have anticancer and antiviral activity in animal models, and it may be a potential treatment for HIV infection. The chemical name for 8-APT is 2'-deoxyguanosine, 8-(4-aminophenyl)-, (8R*,9S*)-.</p>Formule :C16H18N6O4Degré de pureté :Min. 95%Masse moléculaire :358.35 g/mol5-Aminoallyl-2'-deoxycytidine
<p>5-Aminoallyl-2'-deoxycytidine is an activator that has been shown to be a novel anticancer drug. It is an analogue of cytidine and is synthesized by the phosphoramidite method. 5-Aminoallyl-2'-deoxycytidine inhibits viral replication in human cells, but also has antiviral activity against HIV and influenza A virus. The compound has been shown to be active against small cell lung cancer in animal models.</p>Degré de pureté :Min. 95%N4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine
<p>N4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine is a synthetic nucleoside that inhibits the enzyme ribonucleotide reductase. It has antiviral and anticancer activities.</p>Degré de pureté :Min. 95%5-Fluoro-1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil
CAS :<p>5-Fluoro-1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil (5FUA) is a monophosphate nucleoside that inhibits viral replication. It is phosphorylated by the viral enzyme 3' to 5' exonuclease and then acts as a competitive inhibitor of the natural substrate, diphosphate, at the active site of DNA polymerase. The result is inhibition of viral DNA synthesis and replication. 5FUA has been shown to be active against a variety of viruses including herpes simplex virus types 1 and 2, varicella zoster virus, influenza A virus, and human immunodeficiency virus type 1. This drug has also been shown to inhibit cancer cell proliferation in vitro.</p>Degré de pureté :Min. 95%2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å
<p>The 2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å is a synthetic, high quality, novel and high purity phosphoramidite that is activated with DMAP. The covalent linkage of the nucleoside to the CPG is made by an amidite coupling reaction. The following compounds have been synthesized on this support: ampicillin, chloramphenicol, gentamicin, kanamycin, neomycin and tetracycline. This product is used in anticancer and antiviral research.</p>Degré de pureté :Min. 95%5-Bromo-2,4-di(benzyloxy)pyrimidine
CAS :<p>5-Bromo-2,4-di(benzyloxy)pyrimidine is an activator of DNA and RNA synthesis. It is a phosphoramidite that is used in the synthesis of oligonucleotides. 5-Bromo-2,4-di(benzyloxy)pyrimidine has antiviral activity and can inhibit the replication of HIV in vitro. This compound also has anticancer activity when it is given as a monophosphate, while its diphosphate form inhibits DNA and RNA synthesis. 5-Bromo-2,4-di(benzyloxy)pyrimidine can be synthesized from 2,4-dibenzyloxy pyrimidine and bromine in high purity with a CAS number 41244-53-5.</p>Formule :C18H15BrN2O2Degré de pureté :Min. 95%Masse moléculaire :371.23 g/mol2'-Deoxyguanosine-5'-monophosphate free acid
CAS :<p>2'-Deoxyguanosine-5'-monophosphate free acid (dGMP) is a nucleotide that can be used as a substrate to measure the activity of protein kinase C. It is also a precursor in DNA synthesis, and its incorporation into DNA is catalyzed by polymerase chain reaction. 2'-Deoxyguanosine-5'-monophosphate free acid has been shown to inhibit transcriptional regulation, which may be related to its interaction with nuclear DNA. Furthermore, it has been shown to have an antioxidant effect due to its ability to donate electrons. 2'-Deoxyguanosine-5'-monophosphate free acid has also been shown to react with sodium salts in plasma mass spectrometry experiments, and titration calorimetry experiments have shown that it reacts with calcium ions in vitro.br></p>Formule :C10H14N5O7PDegré de pureté :Min. 95%Masse moléculaire :347.22 g/mol3-Deazauridine-5'-triphosphate triethylamine salt
CAS :<p>3-Deazauridine-5'-triphosphate triethylamine salt is a xanthosine analog that has been used as a biochemical reagent in animals and humans. It is postulated to be a potential cancer therapeutic agent because of its ability to inhibit DNA synthesis and cell division. 3-Deazauridine-5'-triphosphate triethylamine salt inhibits the biosynthesis of uridine in leukemic mice, hamster V79 cells, and mammalian cells. This drug inhibits the incorporation of uracil into RNA by competitive inhibition with respect to ATP. 3DATTP also inhibits the incorporation of thymidine into DNA by competitive inhibition with respect to dCTP.</p>Formule :C10H16NO15P3Degré de pureté :Min. 95%Masse moléculaire :483.15 g/molN6-(4-Methyoxybenzoyl)adenosine
CAS :<p>N6-(4-Methoxybenzoyl)adenosine is an adenine base that is a furanose sugar, with a glycosidic bond. The furanose ring has a phenyl group and an adenine base in the conformation of pyranose. The phenyl ring is in the geometry of chair form and is bonded to the 6' position of the adenosine base. N6-(4-Methoxybenzoyl)adenosine has a glycosidic bond at C1' - C5'. It has an angstrom distance between C1'-C2' and C3'-C5'.</p>Formule :C18H19N5O6Degré de pureté :Min. 95%Masse moléculaire :401.37 g/mol
