Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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5-Phenylcytidine
CAS :5-Phenylcytidine is a nitro compound that is used as an antiviral agent. It inhibits the replication of the virus by interfering with viral DNA synthesis and preventing the assembly of viral proteins. 5-Phenylcytidine is also capable of inhibiting influenza A virus in vitro at concentrations below 1 μM and has been shown to inhibit herpes simplex virus type 1 (HSV-1) in cell culture. The antiviral activity of 5-phenylcytidine may be due to its ability to form a stable reaction product with cytosine in alkaline conditions, which prevents the incorporation of this nucleobase into DNA or RNA.Degré de pureté :Min. 95%Xanthosine-5'-monophosphate ammonium salt
CAS :Xanthosine-5'-monophosphate ammonium salt is a monophosphate compound that is formed by the reaction of xanthosine and ammonium hydroxide. It has been shown to have an optimum concentration of 1 mM in dextran sulfate solutions and to be active against a range of bacteria at this concentration. The antimicrobial activity of xanthosine-5'-monophosphate ammonium salt is due to its inhibition of energy metabolism and synthesis, which leads to cell death. Xanthosine-5'-monophosphate ammonium salt also inhibits the production of tetracycline resistance in leukemic mice and k562 cells, which may be due to its ability to form a complex enzyme with tetracycline synthetase.Degré de pureté :Min. 95%3'-O-Allyluridine
3'-O-Allyluridine is a nucleoside that has antiviral, anticancer, and antibacterial activities. 3'-O-Allyluridine is an activator of RNA polymerase and is used to synthesize DNA in vitro. It can be used as a substrate for phosphoramidites in the synthesis of oligonucleotides with modified backbones. 3'-O-Allyluridine has been shown to inhibit the growth of cancer cells by blocking the synthesis of DNA and RNA. The drug also inhibits the production of ribonucleases, which are enzymes that break down RNA in cells.Formule :C12H16N2O6Degré de pureté :Min. 95%Masse moléculaire :284.27 g/molN4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-2'C-methylcytidine 3'-CE phosphoramidite
N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-2'C-methylcytidine 3'-CE phosphoramidite is a novel, deoxynucleoside phosphoramidite with high purity and high quality. It has been used in the synthesis of anticancer agents, ribonucleotide analogues and antiviral agents. N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-2'C-methylcytidine 3'-CE phosphoramidite can be used as an activator for DNA polymerase to synthesize DNA molecule.Formule :C53H68N5O9PSiDegré de pureté :Min. 95%Masse moléculaire :978.19 g/molAdenylyl-3'-5'-uridine ammonium salt
CAS :Adenylyl-3'-5'-uridine ammonium salt is a novel antiviral agent that has been shown to inhibit the activity of viral DNA polymerase, RNA polymerase and reverse transcriptase. It is also an anticancer agent that can be used as a cytotoxic agent against leukemia and lymphoma cells. Adenylyl-3'-5'-uridine ammonium salt is synthesized by the reaction of adenosine monophosphate with uracil in the presence of phosphate and ammonia. This compound can then be converted to ribonucleosides or deoxyribonucleosides by phosphorylation. SYNONYMS: AMP-uridine; AMP-U; UMPFormule :C19H24N7O12PDegré de pureté :Min. 95%Masse moléculaire :573.41 g/molN6-(tert-Butylphenoxyacetyl)-2'-O-methyl-5'-O-DMT-adenosine 3'-CE phosphoramidite
N6-(tert-Butylphenoxyacetyl)-2'-O-methyl-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel anticancer, antiviral and antifungal agent. It is synthesized by reacting the nucleoside adenosine with tert-butyl phenoxyacetic acid to form an activated ester derivative which reacts with 2'-O-methyl 5'-O-DMT in the presence of a phosphoramidite reagent to form a DNA precursor. The modified nucleotide has been shown to have high purity and good quality, as well as high antiviral and anti-cancer activities.Formule :C53H64N7O9PDegré de pureté :Min. 95%Masse moléculaire :974.09 g/molThymidine 5’-triphosphate sodium hydrate
Thymidine 5’-triphosphate (dTTP) sodium hydrate is a fundamental building block in chemical biology. As one of the four natural deoxynucleotides, it plays a crucial role in DNA replication and repair, where dTTP is incorporated into growing DNA strands by DNA polymerases, ensuring fidelity during genetic duplication. The use of dTTP spans various applications, including PCR, DNA sequencing, and site-directed mutagenesis.
Degré de pureté :Min. 95%5-Chloro-1-(b-D-arabinofuranosyl)cytidine
CAS :5-Chloro-1-(b-D-arabinofuranosyl)cytidine is a monophosphate that is used as a precursor in the synthesis of antiviral and anticancer drugs. 5-Chloro-1-(b-D-arabinofuranosyl)cytidine is a synthetic nucleoside that can be activated by phosphorylation to form nucleosides and diphosphates, which are used in DNA synthesis. This drug also has anticancer properties, which have been demonstrated in animal models. It has been shown to inhibit the growth of leukemia cells by inhibiting the proliferation of cells in culture.Formule :C9H12CIN3O5Degré de pureté :Min. 95%Masse moléculaire :277.66 g/molN4-Acetyl-5'-O-DMT-cytidine 3'-CE phosphoramidite
N4-Acetyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a monophosphate nucleoside that is an important building block in nucleic acid synthesis. It has been shown to be effective against cancer cells and HIV infection. N4-Acetyl-5'-O-DMT-cytidine 3'-CE phosphoramidite also inhibits the production of viral proteins, including new viral particles, by binding to the RNA polymerase enzyme in cells. This compound can be used as a novel antiviral agent for the treatment of human immunodeficiency virus type 1 (HIV1) infections.Degré de pureté :Min. 95%5'-O-DMT-N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine 3'-CE phosphoroamidite
5'-O-DMT-N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine 3'-CE phosphoroamidite is a high purity, modified phosphoramidite that is used as an activator for the synthesis of DNA. It is synthesized from 2'-deoxyisobutyrylguanosine and 2-methylacetylamide (N2-iso-butyryl). 5'-O-DMT-N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine 3'-CE phosphoroamidite has a novel structure and is used in anticancer therapy. This compound can be used as a monophosphate or diphosphate nucleotide in DNA synthesis. 5'-O-DMT-N2-Isobutyryl - 2'- O-(2 - methylacetamido)Degré de pureté :Min. 95%2'-Deoxy-N2-isobutyryl-a-cytidine
2'-Deoxy-N2-isobutyryl-a-cytidine (DBIC) is a modified nucleoside that is used in the synthesis of DNA. It is an activator that can be used to enhance the antitumor effects of other drugs. DBIC has been shown to inhibit the proliferation of human tumor cells by inactivating the p53 protein, which regulates cell cycle progression and suppresses tumorigenesis. This drug also has antiviral, anticancer, and anti-inflammatory properties.Formule :C13H19N3O5Degré de pureté :Min. 95%Masse moléculaire :297.31 g/molN4-Acetyl-2'-Deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å
N4-Acetyl-2'-Deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å is a nucleoside analog. It is an antiviral and anticancer agent that inhibits the synthesis of DNA. This compound has a high purity, reactivity and solubility. N4-Acetyl-2'-Deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å can be used in the synthesis of oligonucleotides for research purposes or as pharmaceutical ingredients.Degré de pureté :Min. 95%4-Amino-5-(2-deoxy-b-D-ribofuranosyl)-1-methyl-2(1H)-pyrimidinone
CAS :4-Amino-5-(2-deoxy-b-D-ribofuranosyl)-1-methyl-2(1H)-pyrimidinone is a novel activator that is a ribonucleoside and deoxyribonucleoside diphosphate, as well as phosphoramidite and modified nucleosides. It has been shown to have anticancer, antiviral, and antimalarial activities in vitro. This compound has been synthesized in high purity and high quality with CAS No. 1166395-05-6.Formule :C10H15N3O4Degré de pureté :Min. 95%Masse moléculaire :241.24 g/mol3'-Deoxy-N6-propionyladenosine
CAS :3'-Deoxy-N6-propionyladenosine is a prodrug that is modified in the body to form adenosine. It has been shown to have a high bioavailability and pharmacokinetic profile, with a high initial concentration and rapid elimination. 3'-Deoxy-N6-propionyladenosine has been shown to be effective against tuberculosis and leprosy, with a half-life of approximately 1 hour. The pharmacokinetic curves for this drug have exceeded those of other drugs used for these diseases.Formule :C13H17N5O4Degré de pureté :Min. 95%Masse moléculaire :307.31 g/mol2'-Deoxy-2'-fluoro-2'-C-methylcytidine
CAS :2'-Deoxy-2'-fluoro-2'-C-methylcytidine is a nucleoside analog with modifications on both the sugar and the nucleobase. It is a derivative of cytidine, with fluorine attached to the 2' carbon of the sugar (deoxyribose) and a methyl group at the 2' carbon of the sugar as well. These modifications provide the compound with unique properties, such as potnetial increased resistance to enzymatic degradation, which can make it useful in antiviral and anticancer applications.Formule :C10H14FN3O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :259.23 g/mol3'-Deoxy-3'-fluoro-2'-C-methylguanosine
CAS :3'-Deoxy-3'-fluoro-2'-C-methylguanosine is a nucleoside analog that is used in the treatment of cancer. It is an activator of the anticancer drug 5-FU, which inhibits DNA synthesis and cell division. 3'-Deoxy-3'-fluoro-2'-C-methylguanosine may also be used as a starting material for the synthesis of other nucleosides, such as 2',3'-deoxyadenosine and 3',5' -deoxycytidine.Formule :C11H14FN5O4Degré de pureté :Min. 95%Masse moléculaire :299.26 g/molN6-Dansylhexyl-5'-ethylcarboxamidoadenosine
CAS :N6-Dansylhexyl-5'-ethylcarboxamidoadenosine is a fluorescent molecule that can be used in the field of microscopy and cytometry. It has been shown to be an adenosine receptor agonist, which may be due to its ability to bind to the adenosine receptor and activate it. This ligand has also been shown to bind with high affinity to the fluorescence resonance transfer protein, resulting in a fluorescent signal. In addition, this molecule is a linker for fluorescence resonance energy transfer between two molecules that are not close enough for direct contact.Formule :C30H40N8O6SDegré de pureté :Min. 95%Masse moléculaire :640.75 g/molN6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE phosphoramidite
CAS :N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE phosphoramidite is an antiviral agent that inhibits the activity of viral DNA polymerase. This chemical has been shown to be effective against herpes virus, pox virus and HIV. N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE phosphoramidite is a novel nucleotide analogue that contains a modified deoxyribose sugar backbone. It has been shown to be active against cancer cells in vitro, but not in vivo.Formule :C47H51FN7O7PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :875.95 g/mol2-Aminopyrimidine-5-boronic acid
CAS :2-Aminopyrimidine-5-boronic acid is a synthetic compound that has been shown to inhibit the activity of cellulase enzymes in vitro. It also has neuroprotective effects and potent inhibition against cancer cells. 2-Aminopyrimidine-5-boronic acid's mechanism of action is reversible covalent, meaning that it reacts with DNA by forming an N2-(2'-aminopyrimidine) adduct with guanine at position 6 in the purine ring. This reaction inhibits DNA synthesis, leading to cell death. 2-Aminopyrimidine-5-boronic acid is not currently being used as a cancer therapy, but it is being researched for its potential use in cancer treatments.
Formule :C4H6BN3O2Degré de pureté :Min. 95%Masse moléculaire :138.92 g/mol2',3'-Di-O-acetyl-5'-O-DMT-5-methyluridine
2',3'-Di-O-acetyl-5'-O-DMT-5-methyluridine is a monophosphate nucleotide, which is an antiviral agent. It is a novel, high quality and high purity compound. The CAS number for 2',3'-Di-O-acetyl-5'-O-DMT-5-methyluridine is 69681-06-8. It has antiviral activity against the herpes simplex virus type 1 (HSV1) and Epstein Barr virus (EBV). This drug also inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. This product can be used in research to synthesize phosphoramidites, activator molecules, and nucleosides.Degré de pureté :Min. 95%
