Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite
CAS :N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite is a novel nucleoside. It is a monophosphate and cytidine analog that has been shown to be effective in the treatment of cancer. N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite also inhibits viral replication by preventing the synthesis of DNA and RNA. This drug can be used as an activator for synthesis of modified oligonucleotides.Formule :C41H50N5O8PDegré de pureté :Min. 95%Masse moléculaire :771.84 g/mol7-Deaza-2'-deoxy-5'-O-DMT-adenosine
CAS :7-Deaza-2'-deoxy-5'-O-DMT-adenosine is a nucleoside that has been synthesized by reacting 7-deaza-2'-deoxyadenosine with 5,6,7,8-tetrahydro-1H-[1]pyrazolo[3,4]pyrimidin-4(3H)-one. It is a novel anticancer agent that has been shown to inhibit the proliferation of various tumor cells in vitro. The cytotoxic effects of 7-deaza-2'-deoxy-5'-O-DMT adenosine are due to its ability to activate DNA synthesis while inhibiting DNA repair. It also inhibits ribonucleotide reductase and protein synthesis.Formule :C32H32N4O5Degré de pureté :Min. 95%Masse moléculaire :552.62 g/molN6,5'-O-Dibenzoyl-2'-deoxy-adenosine
N6,5'-O-Dibenzoyl-2'-deoxy-adenosine is a monophosphate nucleoside that is used in the synthesis of DNA. It is synthesized from 2'-deoxyadenosine, which is an antiviral agent against influenza virus and anticancer agent. N6,5'-O-Dibenzoyl-2'-deoxy-adenosine has been shown to be a potent activator of the polymerase chain reaction with high purity and novel properties.Formule :C24H21N5O5Degré de pureté :Min. 95%Masse moléculaire :475.45 g/molL-Ribose NAD
L-Ribose NAD is a nucleoside that belongs to the group of ribonucleosides. It is a novel modified monophosphate and diphosphate nucleotide. L-Ribose NAD has antiviral, anticancer, and immunomodulatory activities. L-Ribose NAD can activate cells with DNA damage by inhibiting the synthesis of deoxyribonucleosides, which are needed for DNA repair. This product has a high purity level and high quality.Degré de pureté :Min. 95%Masse moléculaire :663 g/molN2-DMF-2'-O-methylguanosine
CAS :N2-DMF-2'-O-methylguanosine is a nucleoside that is used as an antiviral agent and anticancer drug. It has been shown to inhibit the growth of human cancer cells in vitro and in vivo. N2-DMF-2'-O-methylguanosine has also been shown to inhibit viral replication by inhibiting DNA synthesis. This nucleoside is a novel compound that can be synthesized using phosphoramidites, which are high quality and yield high purity products.
Formule :C14H20N6O5Degré de pureté :Min. 95%Masse moléculaire :352.35 g/mol5'-O-DMT-2'-O-hexylaminoadenosine
5'-O-DMT-2'-O-hexylaminoadenosine is a modified nucleoside that has antiviral activity. It is the monophosphate form of 5'-O-DMT-2'-O-hexylaminoadenosine, and it is used in the synthesis of phosphoramidites for DNA and RNA. This nucleoside is also an activator for novel antiviral drugs.Formule :C37H44N6O6Degré de pureté :Min. 95%Masse moléculaire :668.8 g/mol5-[(Methylamino)methyl]uridine
CAS :5-[(Methylamino)methyl]uridine is a proton-containing analog of uridine. It is an epigenetic modifier that has been shown to have conformational properties that are similar to those of uridine. 5-[(Methylamino)methyl]uridine has been shown to modify the glycosidic bond and ring structures, which are important for its function in protein synthesis. The compound can also be found as a chemical structure in the ribosomal subunit, where it is involved in protein synthesis and translation. 5-[(Methylamino)methyl]uridine has shown potential as a therapeutic agent for cancer treatment due to its ability to inhibit the expression of oncogenes in cells and induce programmed cell death (apoptosis).Formule :C11H17N3O6Degré de pureté :Min. 95%Masse moléculaire :287.27 g/mol2-Amino-4-methoxypyrimidine
CAS :2-Amino-4-methoxypyrimidine is an organic compound that can be synthesized from 2-amino-4-chloropyrimidine. It is a colorless, water soluble solid with a melting point of 166°C. The UV spectrum of 2-amino-4-methoxypyrimidine exhibits absorption maxima at 240 nm and 280 nm. When 2-amino-4-methoxypyrimidine is exposed to UV light, it emits fluorescent light at 360 nm. The IR spectrum exhibits absorption bands at 3200 cm−1, 1650 cm−1, and 1530 cm−1. Hydrogen bonding interactions occur between the methoxy group and the protonated amine group in the molecule's structure. The yield of this reaction was found to be 65% by GC analysis. This reaction occurs in two steps: first, the imino group reacts with n hexane to form an iminium ion
Degré de pureté :Min. 95%[1',2',3',4',5'-13C5]-4-Thiothymidine
[1',2',3',4',5'-13C5]-4-Thiothymidine is an antiviral, anticancer, and activator of DNA synthesis. It is a monophosphate analog of thymidine that has been modified to include a radioactive isotope. [1',2',3',4',5'-13C5]-4-Thiothymidine binds to the active site of the enzyme ribonucleotide reductase which is responsible for the production of DNA from RNA. The incorporation of this radioactively labeled analog into DNA prevents its degradation by nucleases and allows for the detection and quantification of DNA synthesis via autoradiography.Degré de pureté :Min. 95%2'-Deoxy-1,N6-dimethyladenosine
2'-Deoxy-1,N6-dimethyladenosine is a nucleoside that is used for the synthesis of DNA and RNA. It has antiviral activity against HIV and herpes simplex virus type 1 (HSV-1). 2'-Deoxy-1,N6-dimethyladenosine binds to viral DNA and inhibits viral replication by preventing the viral DNA from being replicated. It also inhibits the synthesis of viral proteins. This nucleoside is synthesized in a high purity and quality, which makes it an excellent starting material for use in the synthesis of other nucleosides or phosphoramidites.Degré de pureté :Min. 95%4,5-Dimethoxy-2-nitrobenzyl adenosine 3',5'-cyclic monophosphate
4,5-Dimethoxy-2-nitrobenzyl adenosine 3',5'-cyclic monophosphate is a synthetic nucleotide that can be activated to form an antiviral and anticancer agent. This compound has been shown to inhibit the proliferation of leukemia cells in culture. It also inhibits the synthesis of DNA and RNA, leading to cell death by inhibiting the production of proteins vital for cell division. 4,5-Dimethoxy-2-nitrobenzyl adenosine 3',5'-cyclic monophosphate is a novel nucleoside with high purity and CAS number: 57314-27-1.Formule :C19H21N6O10PDegré de pureté :Min. 95%Masse moléculaire :524.38 g/molAFB-guanine
CAS :AFB-guanine is a purine nucleoside that has been found to be an intermediate in the conversion of adenosine to inosine. The toxicity of AFB-guanine was studied using the model system of rat liver microsomes and human liver. It was observed that AFB-guanine is metabolized by glycosylases, which act on purines and pyrimidines. The glycosylase activity was inhibited by dicoumarol, which results in a decrease in the amount of AFB-guanine that is converted to adenosine triphosphate (ATP). The study also showed that histological analysis revealed degenerative diseases and cancer in mice fed with AFB-guanine, suggesting that this compound may be carcinogenic.Formule :C22H17N5O8Degré de pureté :Min. 95%Masse moléculaire :479.4 g/mol5-Methylcytidine HCl
5-Methylcytidine HCl is a novel antiviral and anticancer agent. It possesses two important properties: it is an activator of the enzyme ribonucleotide reductase, which regulates DNA synthesis and repair; and it inhibits the activity of DNA polymerases. It is also chemically modified to allow its use in phosphoramidite synthesis. 5-Methylcytidine HCl has been shown to cause apoptosis in cancer cells, as well as inhibit the growth of bacteria.Formule :C10H15N3O5·HClDegré de pureté :Min. 95%Masse moléculaire :293.7 g/mol2-[2-(4-Fluorophenyl)ethoxy]adenosine
CAS :2-[2-(4-Fluorophenyl)ethoxy]adenosine is a hydrogen-bonded, hydrated, switchable molecule. The techniques used to characterize this compound include vibrational spectroscopy and Raman spectroscopy. 2-[2-(4-Fluorophenyl)ethoxy]adenosine has been shown to have high salt and thermal stability. It has also been shown to undergo conformational changes in the presence of chemists.Formule :C18H20FN5O5Degré de pureté :Min. 95%Masse moléculaire :405.38 g/molCarbocyclic 2'-deoxyguanosine
CAS :Carbocyclic 2'-deoxyguanosine is an analog of the nucleoside guanosine, and it is a prodrug that is converted to the active form, carbocyclic 2'-deoxyguanosin-8-yl-1-beta-D-arabinofuranoside, in vivo. This drug inhibits viral thymidine kinase and has been shown to be effective against HIV infection in clinical studies. Carbocyclic 2'-deoxyguanosine has been shown to inhibit virus proliferation by interfering with viral DNA synthesis and replication. It also blocks transcription of the HLA class I molecule by binding to its promoter region. Carbocyclic 2'-deoxyguanosine may have therapeutic potential for treating herpes simplex virus infections. The drug is being developed as an oral prodrug to treat patients with mild to moderate symptoms of herpes simplex virus infection.Formule :C11H15N5O3Degré de pureté :Min. 95%Masse moléculaire :265.27 g/mol2,5'-Anhydro-thymidine
CAS :2,5'-Anhydro-thymidine is an analog of thymidine that is used in the diagnosis of women with suspected acute ischemic brain damage. It is a colony-stimulating factor that can be activated by the presence of inflammatory bowel disease or bowel disease. 2,5'-Anhydro-thymidine has been shown to cause ventricular dysfunction and to increase levels of brain natriuretic peptide in mice undergoing rotarod tests. The use of this compound has been shown to improve outcomes in animal models of acute ischemic brain damage and cancer.Formule :C10H12N2O4Degré de pureté :Min. 95%Masse moléculaire :224.21 g/mol2'-O-tert-Butyldimethylsilyl-O4-(4-chlorophenyl)-5'-O-DMT-uridine 3'-CE-phosphoramidite
CAS :2'-O-tert-Butyldimethylsilyl-O4-(4-chlorophenyl)-5'-O-DMT-uridine 3'-CE-phosphoramidite is a nucleoside that is used in the synthesis of DNA. It is a novel synthetic nucleotide with antiviral and anticancer properties. The phosphoramidite has been modified to give it high purity, and the monophosphate form has been synthesized. This nucleotide is synthesized through the use of an Activator, which activates the 2' position of the sugar moiety on the 5' phosphate terminus. This product is of high quality due to its high purity and novel synthetic nature.Formule :C51H64CIN4O9PSDegré de pureté :Min. 95%Masse moléculaire :971.6 g/mol2'-Deoxy-2'-fluoro-2'-C-methyl-5-methyluridine
2'-Deoxy-2'-fluoro-2'-C-methyl-5-methyluridine is a modified nucleoside that inhibits the proliferation of cancer cells. It has been shown to be effective against HIV, Hepatitis B and C, influenza, herpes simplex virus type 1 and 2, and human cytomegalovirus. This drug is synthesized by phosphoramidite chemistry and is used as a DNA activator in the synthesis of oligonucleotides. 2'-Deoxy-2'-fluoro-2'-C-methyl-5-methyluridine is a novel compound that exhibits high quality with high purity.Degré de pureté :Min. 95%5-O-DMT-thymidine 3'-H phosphonate triethylammonium
5-O-DMT-thymidine 3'-H phosphonate triethylammonium is a novel nucleoside analogue with anticancer activity. The monophosphate form of 5-O-DMT-thymidine 3'-H phosphonate triethylammonium is an activator of DNA, RNA, and protein synthesis in vitro. 5-O-DMT-thymidine 3'-H phosphonate triethylammonium has been shown to be active against herpes simplex virus type 1 and 2 and HIV type 1 in vitro.
Formule :C37H48N3O9PDegré de pureté :Min. 97 Area-%Couleur et forme :White/Off-White SolidMasse moléculaire :709.77 g/mol2-Fluoroinosine
CAS :2-Fluoroinosine is a chemical that inhibits protein synthesis by blocking the attachment of amino acids to their corresponding tRNA molecules. This drug is used in the treatment of cancer, as it inhibits cell growth and prevents tumor cells from dividing. 2-Fluoroinosine has been shown to be effective against human leukaemia cells, with its inhibitory properties being due to its ability to dephosphorylate the enzyme RNA polymerase II. This drug also has anti-malarial properties and can be used for the treatment of Chagas disease. 2-Fluoroinosine is synthesized from xanthosine, which is an intermediate in purine metabolism and can be obtained from naturally occurring sources or chemically through a solid phase synthesis. 2-Fluoroinosine is activated by UV light and can be synthesized using single stranded DNA or synthetases such as those found in calf thymus tissue. The catalytic mechanism of this drug hasFormule :C10H11FN4O5Degré de pureté :Min. 95%Masse moléculaire :286.22 g/mol
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