Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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2'-Deoxy-5'-O-DMT-N2-isobutyryl-3'-xanthylguanosine
2'-Deoxy-5'-O-DMT-N2-isobutyryl-3'-xanthylguanosine is a diphosphate synthetic activator. It has been shown to be an effective anticancer and antiviral agent.Formule :C46H49N5O8SDegré de pureté :Min. 95%Masse moléculaire :832 g/mol2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-Me phosphoramidite
2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-Me phosphoramidite is a modified nucleoside monophosphate with antiviral and anticancer activity. It is synthesized by the reaction of 2'-deoxyguanosine 5'-O-DMT (dG) with 4-isopropylphenoxyacetic acid in the presence of triethylamine and tetrazole. The product is purified by crystallization. This compound has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) in human lymphocytes, which may be due to its ability to inhibit the synthesis of DNA, RNA, or both.Formule :C49H59N6O9PDegré de pureté :Min. 95%Masse moléculaire :907.03 g/mol2'-Deoxy-5'-O-trityluridine
CAS :2'-Deoxy-5'-O-trityluridine is a nucleoside that has been synthesized for visualization purposes. It is an analog of uridine, with the structure shown in Figure 1. The trityl group is oriented on the 2' oxygen atom, which is attached to the ribose sugar. This configuration allows for a variety of interactions with other molecules and can be seen in Figure 2. The methyl group on the 5' carbon atom interacts with the benzene ring on xylene, while the moiety on the 3' carbon atom interacts with furanose. This nucleoside also has a symmetric conformation, as shown in Figure 3.Formule :C28H26N2O5Degré de pureté :Min. 95%Masse moléculaire :470.52 g/mol2'-Deoxycytidyl-(3'-5')-2'-deoxyguanosine
CAS :2'-Deoxycytidyl-(3'-5')-2'-deoxyguanosine is a monophosphate nucleoside. It is an antiviral agent that inhibits the synthesis of DNA and RNA. 2'-Deoxycytidyl-(3'-5')-2'-deoxyguanosine has also been shown to be cytotoxic against cancer cells, with activities against leukemia and lymphoma cells. This drug can be used in the treatment of various cancers, such as chronic myelogenous leukemia, acute myelogenous leukemia, multiple myeloma, Hodgkin's lymphoma, and breast cancer.
Formule :C19H25N8O10P·NH3Degré de pureté :Min. 95%Masse moléculaire :573.45 g/molPyrimidine-5-carbothioic acid amide
CAS :Pyrimidine-5-carbothioic acid amide (PCA) is an organic compound that contains a pyrimidine ring and a carboxylic acid amide group. PCA forms crystalline solids with the molecular formula C4H10N2O4. The x-ray crystal structure of PCA has been determined, revealing the molecule to have a chair conformation with two hydrogen bonds. The molecule can be considered as stabilized by the base formation between the nitrogen atom in the pyrimidine ring and the oxygen atom in the carboxylic acid amide group. PCA has been used as a building block for other molecules, such as enamines, which are useful for computation studies. PCA is also an intermediate in chemical reactions involving nucleophilic substitution reactions and hydrogen abstraction reactions.Formule :C5H5N3SDegré de pureté :Min. 95%Masse moléculaire :139.18 g/molN1-Methyl-2'-O-methyladenosine
N1-Methyl-2'-O-methyladenosine is a phosphoramidite, deoxyribonucleoside and ribonucleoside analog that has antiviral activity. It inhibits the synthesis of viral DNA and RNA by competitive inhibition of viral DNA polymerases. N1-Methyl-2'-O-methyladenosine also inhibits the proliferation of tumor cells in vitro, which is mediated by its ability to inhibit the synthesis of cellular DNA. This drug has novel chemical structures with anticancer activity.Degré de pureté :Min. 95%2-Bromoadenosine
CAS :2-Bromoadenosine is a nucleoside that is structurally similar to adenosine. It has shown to have high resistance against blood pressure and l1210 cells. 2-Bromoadenosine also inhibits kinase activities in microns and spontaneous cell cultures, as well as chemical diversity. This drug has been shown to have high values in neurotransmission, carbonic anhydrase, cardiac muscle, and RNA synthesis. 2-Bromoadenosine blocks the receptor of adenine nucleotides, which causes cell death by inhibiting the production of adenosine. This product may be used for the treatment of cardiac disease or cancer.
Formule :C10H12BrN5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :346.14 g/mol3'-Deoxy-3'-N-MMT-thymidine 5'-CE phosphoramidite
3'-Deoxy-3'-N-MMT-thymidine 5'-CE phosphoramidite is a modified nucleoside. It is used as an activator in the synthesis of DNA and RNA.Degré de pureté :Min. 95%LDA
CAS :LDA is a technique for extracting spectral features from a set of spectra. It uses the probabilistic model of discriminant analysis to discriminate between groups of spectra. LDA has been shown to outperform other techniques, such as PCA and MDA, in analyzing datasets with a small number of variables. The algorithm is incrementally updated with new data points and parameters, which makes it an attractive choice for real-time applications.
Degré de pureté :Min. 95%2,2'-Anhydrocytidine
CAS :2,2'-Anhydrocytidine is a cytosine analogue that has been shown to have anticancer activity against solid tumours in mice. The mechanism of action of 2,2'-Anhydrocytidine is not fully understood, but it may be due to its ability to bind to fatty acids and tubule cells in the liver. This compound also induces the production of epidermal growth factor (EGF) and has been shown to inhibit the phase transition temperature of nuclear DNA. It can be used as a model system for hydrogen bonding interactions and chemical stability. 2,2'-Anhydrocytidine can also be used for tissue culture experiments or as a reaction solution in vivo.
Formule :C9H11N3O4Degré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :225.2 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Sp-oxazaphospholidine
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Sp-oxazaphospholidine is a novel antiviral drug that has been synthesized for the treatment of cancer and viral infections. This compound has been modified to increase its antiviral activity, which is due to its ability to inhibit DNA synthesis. The antiviral activity of N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Sp-oxazaphospholidine was shown in vitro using human and mouse cells infected with herpes simplex virus (HSV) type 1 and 2.Degré de pureté :Min. 95%7-(Aminomethyl)-7-deazaguanosine
CAS :7-Aminomethyl-7-deazaguanosine is a nucleoside that is classified as a purine. It can be synthesized from 7-amino-7-deazaguanosine and sodium periodate. The chemical reactions involved in the synthesis are oxidation of the amine group on the 7-amino group to form an iminium ion and subsequent nucleophilic attack by the hydroxyl group on the N9 position of the purine ring to form an amino alcohol. This nucleoside has been shown to bind to ribosomes and inhibit protein synthesis, which suggests that it may have potential for use as an antibiotic or anticancer agent. 7-Aminomethyl-7-deazaguanosine has also been shown to cause epigenetic changes such as DNA methylation, histone modification, and alterations in chromatin structure.Formule :C12H17N5O5Degré de pureté :Min. 95%Masse moléculaire :311.29 g/mol5-Methoxyuridine 5′-triphosphate sodium, 85mM/L aqueous solution
CAS :Please enquire for more information about 5-Methoxyuridine 5′-triphosphate sodium, 85mM/L aqueous solution including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C10H17N2O16P3•NaxDegré de pureté :Min. 95%5'-O-DMT-2'-ethylfluoro-5-methyluridine
5'-O-DMT-2'-ethylfluoro-5-methyluridine is an activated nucleotide that is used as a synthetic, nonnatural substrate for DNA polymerases. It has been shown to have anticancer and antiviral activities. 5'-O-DMT-2'-ethylfluoro-5-methyluridine is highly pure and of high quality, which makes it suitable for use in research or other applications requiring a high level of purity.Degré de pureté :Min. 95%5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine
5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine is a synthetic nucleoside with antiviral and anticancer activity. It is a modified nucleotide that has been synthesized by the activation of 2'-deoxyadenosine monophosphate with 4-isopropylphenoxyacetic acid, followed by the addition of methylguanine methyl ester to give 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine. This novel nucleoside is an activator of DNA polymerases and is used for the synthesis of DNA, RNA, and proteins. It has been shown to have anti-inflammatory properties in animal models. 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine was first synthesizedDegré de pureté :Min. 95%3',5'-Di-O-acetyl-2'-deoxy-D-uridine
CAS :3',5'-Di-O-acetyl-2'-deoxy-D-uridine is a protonated nucleotide that is synthesized from uridine and acetyl coenzyme A. It has been used as a marker for nucleic acids research, because it is stable at temperatures up to 60 degrees Celsius. 3',5'-Di-O-acetyl-2'-deoxy-D-uridine has been shown to have resonances in the proton region at high field strengths and population shifts in the hydrogen bond region.Formule :C13H16N2O7Degré de pureté :Min. 95%Masse moléculaire :312.28 g/molN4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite
N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is an antiviral, anticancer and nucleoside phosphoramidite. It is a novel DNA building block with antiviral activity against HIV and Hepatitis C. The synthesis of N4-acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is based on the reaction of cytosine monophosphate with 2,4,6,-trimethoxybenzoyl chloride. This compound has also been shown to inhibit the proliferation of leukemia cells in vitro and has potential as a chemotherapeutic agent for cancer treatment.Formule :C43H54N5O9PDegré de pureté :Min. 95%Masse moléculaire :815.89 g/molCytidine-5'-triphosphate, lithium salt
Cytidine-5'-triphosphate, lithium salt (CTP, Li) is a monophosphate that is used as a cofactor in the synthesis of DNA and RNA. It is also used for the treatment of viral infections. CTP, Li has antiviral activity against herpes simplex virus type 1 and 2 (HSV-1 and HSV-2), varicella zoster virus (VZV), human cytomegalovirus (CMV) and Epstein-Barr virus (EBV). CTP, Li can be used to inhibit the growth of cancer cells by modifying DNA.Degré de pureté :Min. 95%5'-O-DMT-N4-isobutyryl-2'-O-methyl-5-methylcytidine
5'-O-DMT-N4-isobutyryl-2'-O-methyl-5-methylcytidine, also known as 5'-O-(4,4'-dimethoxytrityl)-N4-isobutyryl-2'-O-methyl-5-methylcytidine, is a nucleoside and nucleotide analog. It is an antiviral agent with anticancer activity. This compound has been shown to be highly active against herpes simplex virus type 1 (HSV1) in vitro. The mechanism of action is not yet fully understood but may involve modification of the viral DNA polymerase.Formule :C36H41N3O8Degré de pureté :Min. 95%Masse moléculaire :643.73 g/mol2'-Methyl-guanosine-(iBu)-succinyl-CPG; 500 Å (RNA)
2'-Methyl-guanosine-(iBu)-succinyl-CPG is a modified nucleoside with antiviral and anticancer properties. It is synthesized by the condensation of 2'-methyl-guanosine and succinic anhydride in the presence of tetrazole. The compound is a phosphoramidite, which is used as a building block for DNA synthesis.Degré de pureté :Min. 95%
