Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3567 produits trouvés pour "Nucléosides"
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2'-O-tert-Butyldimethylsilyl-5'-O-MMT-uridine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-5'-O-MMT-uridine 3'-CE phosphoramidite is a monophosphate that is synthesized by reacting 2'-O-tert-butyldimethylsilyl-5'-O-methylguanosine 3'-CE with uridine 3'-CE. This nucleoside has been shown to be an activator of the immune system and to inhibit cancer cell growth in vitro. It also inhibits the synthesis of DNA and RNA, as well as ribonucleosides and deoxyribonucleosides. The purity of this product is high, with no detectable impurities or toxic substances known to the manufacturer. It is also stable at room temperature for at least six months. This product does not contain any phosphate groups or other reactive functional groups that could interfere with downstream reactions.<br>2'-O-tert-Butyldimethylsily</p>Formule :C44H59N4O8PSiDegré de pureté :Min. 95%Masse moléculaire :831.04 g/molN4-Acetyl-2'-deoxycytidine
CAS :<p>N4-Acetyl-2'-deoxycytidine is a nucleoside analogue that acts as an inhibitor of DNA synthesis. It binds to the active site of the enzyme ribonucleotide reductase, blocking the conversion of ribonucleotides to deoxyribonucleotides. This prevents DNA synthesis and replication, which leads to cell death. N4-Acetyl-2'-deoxycytidine has been shown to be more efficient than other analogues in terms of energy efficiency, control levels, and constant linear model. This compound is reactive and can cause low yields when isolated from solutions with high concentrations. A diode can be used for analytical purposes, while calcium binding may be used as a mathematical model in order to analyze this drug.</p>Formule :C11H15N3O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :269.25 g/mol8-(2-Amino-1-methyl-D3-6-phenylimidazo[4,5-b]pyridyl-2'-deoxyguanosine
CAS :Produit contrôlé<p>8-(2-Amino-1-methyl-D3-6-phenylimidazo[4,5-b]pyridyl-2'-deoxyguanosine) is a modified nucleoside that is used as an antiviral agent. It is not active against DNA viruses but has been shown to inhibit the replication of RNA viruses such as human immunodeficiency virus type 1 (HIV). 8-(2-Amino-1-methyl-D3-6-phenylimidazo[4,5-b]pyridyl)-2'-deoxyguanosine has been found to be more effective than acyclovir (Zovirax), a commonly used antiviral drug. This nucleoside also has anticancer properties, which may be due to its ability to inhibit the synthesis of DNA and RNA.</p>Formule :C23H20D3N9O4Degré de pureté :Min. 95%Masse moléculaire :492.5 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite
CAS :<p>2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite is a nucleoside analogue that has been modified to contain an isobutyryl group. It is an activator of the polymerase enzyme, which helps to synthesize DNA. This product can be used in the synthesis of oligonucleotides for use as therapeutic or diagnostic agents.<br>It has anticancer and antiviral activities, due to its ability to inhibit viral replication. This product also has high purity and quality.</p>Formule :C44H54N7O8PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :839.92 g/mol1-(2'C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one
CAS :<p>1-(2'C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one (1) is a synthetic nucleoside that has been modified to be activated with the addition of a phosphoryl group. It inhibits viral replication by inhibiting viral DNA synthesis. It also inhibits cancer cell growth, and has shown potential as an antiviral agent against HIV, herpes simplex type 2, and influenza A viruses. 1 is a novel monophosphate nucleoside with high purity and high quality. CAS No. 2072145-17-4.</p>Degré de pureté :Min. 95%2'-O-Methyl-N6-phenoxyacetyladenosine
CAS :<p>2'-O-Methyl-N6-phenoxyacetyladenosine is a phosphoramidite nucleoside that is used in the synthesis of DNA and RNA. It has antiviral, anticancer, and antiribonucleases properties. The chemical structure of 2'-O-Methyl-N6-phenoxyacetyladenosine is similar to that of adenosine, but contains a methyl group on C2' position and an oxyalkyl group on N6. This compound can be used as a novel anticancer agent and has been shown to have high affinity for the purine receptor, inhibiting cancer cell proliferation by activating the p53 tumor suppressor pathway.</p>Formule :C19H21N5O6Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :415.41 g/mol8-Azidoadenosine 5'-monophosphate sodium salt
CAS :<p>8-Azidoadenosine 5'-monophosphate sodium salt is an azido-conjugated adenosine monophosphate derivative used to introduce a label on oligonucleotides. A click reaction between the azide-functionalised nucleotide and a terminal alkyne-functionalised labelled moiety (with either a fluorophore or biotin) generates a stable conjugate containing a triazole link.</p>Formule :C10H13N8O7PDegré de pureté :Min. 95%Masse moléculaire :388.23 g/molN4-Benzoyl-2-aza-3’-deazaadenine
CAS :<p>N4-Benzoyl-2-aza-3’-deazaadenine is a modified nucleoside that is synthesized from the natural deoxyribonucleoside adenine. It has been shown to have antiviral and anticancer properties. N4-Benzoyl-2-aza-3’-deazaadenine is a DNA Activator and can be used in the treatment of viral infections, such as HIV and herpes, as well as cancer. The drug binds to the viral DNA polymerase and prevents it from making new copies of the virus. This results in an accumulation of defective viruses within infected cells and ultimately cell death.</p>Degré de pureté :Min. 95%2-Thiocytidine
CAS :<p>2-Thiocytidine is a nucleoside that is an intermediate in the synthesis of thiamine. It has been shown to be effective in the treatment of prostate cancer cells, which may be due to its ability to inhibit protein synthesis. 2-Thiocytidine binds to the catalytic site of ribonucleotide reductase (RR) and inhibits the enzyme's activity, thereby inhibiting DNA synthesis. This drug also has been shown to inhibit crosslinking caused by UV light or other agents that generate reactive oxygen species. 2-Thiocytidine binds to the active site of RR and prevents the formation of the enzyme-substrate complex. This binding prevents reduction of ribose into ribonucleotides and inhibits DNA synthesis.</p>Formule :C9H13N3O4SDegré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :259.28 g/molN6-Benzoyl-2'-O-methyladenosine
CAS :<p>N6-Benzoyl-2'-O-methyladenosine is a nucleoside that is chemically synthesized. It has been shown to be an inhibitor of the polyhedrosis virus, which causes an infectious disease in silkworms. N6-Benzoyl-2'-O-methyladenosine also inhibits viral replication by interfering with the synthesis of messenger RNA. This compound can be used as a silver nitrate or silver salt prodrug for treating diseases caused by viruses and bacteria. This drug is not active against DNA viruses because it does not possess phosphate groups on its structure.</p>Formule :C18H19N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :385.37 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine
CAS :<p>N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine is a cytosine analog with high affinity for the T cell receptor. It can be used to generate antibodies against cytosine and as a screening tool for plasmon resonance.</p>Formule :C32H32FN3O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :589.61 g/mol5'-O-p-Anisoyl-D3-thymidine
Produit contrôlé<p>5'-O-p-Anisoyl-D3-thymidine is a nucleoside analogue that is used in antiviral and anticancer treatments. It is synthesized by the condensation of 3,4-dihydroxyacetophenone with 2,6-diaminopurine followed by phosphorylation of the 5' hydroxyl group. This product has been shown to be an activator of both DNA polymerase and RNA polymerase. In addition, it can inhibit the production of viral proteins such as HIV protease without affecting protein synthesis in mammalian cells. It also inhibits cancer cell growth by stopping DNA replication at the G2 phase.<br>5'-O-p-Anisoyl-D3-thymidine has been shown to be highly purified and can be used for research purposes. This product may have a CAS number but it will not be listed on this website due to company policy.</p>Formule :C18H17N2O7D3Degré de pureté :Min. 95%Masse moléculaire :379.38 g/mol4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
CAS :<p>4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a nucleoside monophosphate that is used as an antiviral agent. It inhibits the synthesis of viral DNA and RNA by inhibiting the activity of enzymes needed for nucleotide synthesis. 4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine has shown anticancer properties in vitro against human colon cancer cells. This drug has been shown to inhibit the growth of tumor cells with high expression levels of cyclin D1 and low levels of p27 (a cell cycle regulatory protein).</p>Degré de pureté :Min. 95%N2,N2-Dimethylguanosine
CAS :<p>N2,N2-Dimethylguanosine is a purine nucleoside that is found in human serum. It belongs to the group of purines and has been shown to be involved in energy metabolism. N2,N2-Dimethylguanosine has been shown to be present at high levels in patients with autoimmune diseases such as rheumatoid arthritis. The x-ray crystal structures of wild-type strains of Escherichia coli and Streptococcus pneumoniae have been determined, which revealed that this compound interacts with the enzyme activity for primary sclerosing cholangitis. This nucleoside can also be detected by LC-MS/MS methods and multivariate logistic regression analysis.</p>Formule :C12H17N5O5Degré de pureté :Min. 98 Area-%Couleur et forme :Off-White PowderMasse moléculaire :311.3 g/molS-Adenosylmethione-1,4-butanedisulfonate
CAS :<p>S-adenosylmethionine is a compound that is naturally produced in the body and has been shown to be involved in many biochemical reactions. It can be found as a supplement at health food stores, but also is available as a prescription for the treatment of certain liver diseases such as hepatitis. S-adenosylmethionine may have some drug transporter function and can affect the metabolism of other drugs.</p>Formule :C42H74N12O28S8Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :1,451.63 g/mol9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl-b-L-ribofuranosyl)-6-chloropurine
CAS :<p>9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl-b-L-ribofuranosyl)-6-chloropurine is a modified nucleoside. It is synthesized by attaching an acetyl group to the 2' position of the sugar moiety and a toluoyl group to the 3' position of the ribose moiety. 9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl]-6 chloropurine has been shown to be an activator of RNA polymerase II and III, which are involved in transcription and replication. This drug also has antiviral properties against influenza virus, herpes simplex virus type 1, Epstein Barr Virus (EBV), and HIV as well as anticancer activity against human cells. 9-[2'-O-Acetyl]-6 chlor</p>Degré de pureté :Min. 95%5'-ODMT-thymidine 3'-Sp-oxazaphospholidine
<p>5'-ODMT-thymidine 3'-Sp-oxazaphospholidine is a modified nucleoside that can be used as an anticancer drug. It is a high purity, diphosphate, Anticancer, Modified, Phosphoramidites. 5'-ODMT-thymidine 3'-Sp-oxazaphospholidine is synthesized by the phosphorylation of thymidine with oxazaphospholidine. It has been shown to inhibit DNA and RNA synthesis in cancer cells.</p>Degré de pureté :Min. 95%3'-Azido-3'-deoxy-b-L-cytidine
CAS :<p>3'-Azido-3'-deoxy-b-L-cytidine is a novel nucleoside that has been shown to be an activator of the ribonuclease activity of purified RNase A in vitro. This product is suitable for use in synthesis of oligodeoxynucleotides and phosphoramidites. 3'-Azido-3'-deoxy-b-L-cytidine can be used as a potential anticancer drug or antiviral agent.</p>Degré de pureté :Min. 95%Cytidine 5'-monophosphate disodium salt
CAS :<p>Cytidine 5'-monophosphate disodium salt (CMPDS) is a prodrug that is converted to cytidine 5'-monophosphate, an active form, in the acidic environment of cancer cells. CMPDS has been shown to inhibit the growth of squamous carcinoma and other solid tumours by binding to survivin, which regulates cell growth and apoptosis. CMPDS also inhibits the activity of matrix metalloproteinases-9 (MMP-9), an enzyme that promotes tumor growth by breaking down connective tissue. This drug can be used as a therapeutic agent for treatment of congestive heart failure due to its ability to increase mitochondrial membrane potential and decrease myocardial infarct size.</p>Formule :C9H12N3Na2O8PDegré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :367.16 g/mol2'-Deoxy-5'-O-MMT-uridine
CAS :<p>2'-Deoxy-5'-O-MMT-uridine is a monophosphate nucleoside that is an antiviral and anticancer drug. It is synthesized from the pentaphosphate derivative of cytosine and uracil, and inhibits RNA synthesis by forming a covalent bond with the enzyme ribonucleotide reductase. This product can be used as a starting material for the synthesis of other nucleosides, such as 2'-deoxy-5'-O-methylcytidine. 2'-Deoxy-5'-O-MMT-uridine can also be used to modify DNA by replacing uracil residues in DNA with their corresponding 2'-deoxy counterparts.</p>Formule :C29H28N2O6Degré de pureté :Min. 95%Masse moléculaire :500.56 g/mol
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