Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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2-Pyrrolidin-1-ylpyrimidine-5-carbaldehyde
CAS :2-Pyrrolidin-1-ylpyrimidine-5-carbaldehyde (2PPi) is a novel synthetic nucleoside analog that is an effective inhibitor of the reverse transcriptase of HIV. 2PPi is a potent antiviral agent and has shown anticancer activity in cell culture. It also inhibits the growth of cancer cells by inhibiting the synthesis of DNA and RNA. This molecule has been synthesized as monophosphate, diphosphate, or deoxyribonucleosides. 2PPi can be used as a building block for other nucleosides and nucleotides, such as phosphoramidites. CAS No. 937796-10-6Formule :C9H11N3ODegré de pureté :Min. 95%Masse moléculaire :177.2 g/molN4-Benzoyl-5-bromo-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite
CAS :N4-Benzoyl-5-bromo-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite is a novel modified cytosine derivative. It has anticancer activity and can be used in the treatment of cancer cells that are resistant to other anticancer drugs. This product has a high purity and quality, which allows it to be widely used in the synthesis of DNA, RNA, and ribonucleosides. In addition, N4-Benzoyl-5-bromo-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite is an activator for diphosphate formation as well as a nucleotide analogue with antiviral effects. This product is also an inhibitor of DNA polymerase α and β, which are enzymes involved in DNA replication.Formule :C46H51BrN5O8PDegré de pureté :Min. 95%Masse moléculaire :912.8 g/mol3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT-uridine
3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT-uridine is a novel, modified nucleoside. This product is an activator of the ribonucleotide reductase enzyme and is used as a precursor in the synthesis of deoxyribonucleosides. It has antiviral activity against herpes simplex virus type 1 and cytomegalovirus. It has also been shown to have anticancer properties, as it inhibits DNA synthesis and tumor cell proliferation without affecting healthy cells. 3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT uridine is synthesized from 5-(3,4,5)-trimethoxybenzaldehyde, 2′(2,6 dichloro)amino]methyl]benzeneacetic acid methyl ester and 5Degré de pureté :Min. 95%N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine
N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine is a nucleoside analog that is used as an antiviral, anticancer, and antiretroviral agent. It is a potent inhibitor of HIV replication in vitro and in vivo. N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine inhibits the activity of viral reverse transcriptase and DNA polymerase by binding to their RNA template strand. The drug shows efficacy against leukemia cells in vitro and against murine leukemia L1210 cells in vivo. Treatment with N4-acetyl-2'-deoxy-5'-O-DMT cytidine has been shown to reduce the size of tumors in mice with fibrosarcoma, melanoma, or glioma xenografts. N4 acetyl 2’ deoxy 5’ O DMT cytidine is alsoFormule :C33H35N3O7Degré de pureté :Min. 95%Masse moléculaire :585.65 g/mol3’-O-(2-Methoxyethyl)adenosine
CAS :3’-O-(2-Methoxyethyl)adenosine is a nucleoside, a kind of building block for DNA. It is an antiviral agent that inhibits viral replication by preventing the incorporation of viral nucleic acid into host DNA. 3’-O-(2-Methoxyethyl)adenosine also has anticancer properties, which makes it useful as a chemotherapeutic agent. 3’-O-(2-Methoxyethyl)adenosine is synthesized from adenosine monophosphate in two steps: first, the methoxy group is attached to the 2’ position of the ribose sugar by phosphoramidite chemistry; second, the 5' hydroxyl group is oxidized to form the phosphate ester.Formule :C13H19N5O5Degré de pureté :Min. 95%Masse moléculaire :325.32 g/mol2',3',5'-Triacetyl -azacytidine
CAS :2',3',5'-Triacetyl-azacytidine is a transcription factor that has dose-dependent effects on the production of melanin. It inhibits the synthesis of melanin by binding to two specific transcription factors, the microphthalmia-associated transcription factor and the histone methyltransferases. This drug also inhibits tyrosinase, which is an enzyme involved in the production of melanin. 2',3',5'-Triacetyl-azacytidine has been shown to inhibit the growth of murine melanoma cells and may be useful for treating skin cancer.Formule :C14H18N4O8Degré de pureté :Min. 95%Masse moléculaire :370.31 g/mol3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine
3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine is a novel nucleoside analog that has been shown to have anticancer activity in vitro. The compound is a monophosphate, which is synthesized from 2'-deoxyuridine and benzoyl chloride. 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine was found to have antiviral activity against herpes simplex virus type 1 (HSV1) and cytomegalovirus (CMV). It also inhibited the production of HIV in human lymphocytes. This nucleoside analog can be activated by phosphorylation at the 5' position to form a diphosphate, which inhibits DNA synthesis by incorporating into the growing DNA chain and preventing the movement of RNA polymerase along the template strand.Formule :C23H19FN2O7Degré de pureté :Min. 95%Masse moléculaire :454.42 g/molL-Inosine
CAS :L-Inosine is a purine nucleoside that is found in plants and animals. It is an intermediate in the pentose phosphate pathway and can be synthesized from the amino acid L-lysine. L-Inosine has been shown to inhibit the growth of trichomonas vaginalis and giardia, but not uninfected human erythrocytes. The mechanism of action of L-Inosine is not well understood, but it may have a role in transporting adenosine into cells. The oral bioavailability of L-Inosine is low due to its rapid conversion to l-adenosine by nonsaturable enzymes. L-Inosine does not appear to be a substrate for transport across mammalian cells, but it does act as a competitive inhibitor for glucose transport.Formule :C10H12N4O5Degré de pureté :Min. 95%Couleur et forme :Off-White SolidMasse moléculaire :268.23 g/mol1-(2'-Deoxy-2'-chloro-b-L-arabinofuranosyl)-thymine
1-(2'-Deoxy-2'-chloro-b-L-arabinofuranosyl)-thymine is a synthetic nucleoside that acts as an activator of DNA synthesis and inhibits viral replication. It is used in the treatment of cancer and antiviral therapy. 1-(2'-Deoxy-2'-chloro-b-L-arabinofuranosyl)-thymine is also used as a building block for the modification of other nucleosides, including deoxyribonucleosides, ribonucleosides, and nucleotides. The drug is available in high purity at a low cost.
Formule :C10H13ClN2O5Degré de pureté :Min. 95%Masse moléculaire :276.67 g/molAdenosine 5′-diphosphoribose monosodium
CAS :Adenosine 5′-diphosphoribose monosodium is a novel nucleotide that can be used in the synthesis of antiviral, anticancer, and anti-inflammatory drugs. Adenosine 5′-diphosphoribose monosodium is a modified form of adenosine 5′-triphosphate (ATP) with an added phosphate group at the 5′ position on the ribose sugar. It is synthesized from ATP by phosphoramidite chemistry. The CAS number for this product is 68414-18-6. Adenosine 5′-diphosphoribose monosodium has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) and herpes simplex virus type 1 (HSV-1).Formule :C15H23N5O14P2•NaDegré de pureté :Min. 95%Masse moléculaire :582.31 g/mol2-Iodo-2',3'-O-isopropylideneadenosine
CAS :2-Iodo-2',3'-O-isopropylideneadenosine is a phosphoramidite nucleoside that is used for the synthesis of oligonucleotide DNA. It has antiviral and anticancer properties, as well as a novel chemical structure. 2-Iodo-2',3'-O-isopropylideneadenosine has been synthesized in high purity and quality. It is also available in CAS No. 141018-25-9.Formule :C13H16IN5O4Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :433.21 g/mol3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite
CAS :3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite is a novel nucleoside, which is structurally similar to cytidine and has been synthesized for the first time. 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite has antiviral and anticancer activities. It inhibits the growth of viruses by inhibiting DNA synthesis. 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite also inhibits the growth of cancer cells by inhibiting RNA synthesis.Formule :C43H53N8O7PDegré de pureté :Min. 95%Masse moléculaire :824.9 g/mol2,2'-Anhydro-5'-O-DMT-thymidine
2,2'-Anhydro-5'-O-DMT-thymidine (2,2'-ADT) is a synthetic nucleoside that is structurally similar to thymidine. It has antiviral and anticancer properties. 2,2'-ADT inhibits viral replication by inhibiting the synthesis of DNA and RNA. This drug has also been shown to inhibit cancer cell growth in vitro and in vivo. In addition, this nucleotide analog has been shown to have efficacy against leukemia cells and against some types of solid tumor cells.
Degré de pureté :Min. 95%Stavudine 5'-monophosphate triethyammonium salt
Stavudine 5'-monophosphate triethylammonium salt is a nucleoside analog that is structurally related to the natural deoxyribonucleosides. It has antiviral activity and is used in the treatment of HIV-1. Stavudine 5'-monophosphate triethylammonium salt inhibits viral replication by inhibiting DNA polymerase, which leads to a decrease in the production of new copies of the virus. This drug has also been shown to have anticancer properties, although it is not currently approved for this use. Stavudine 5'-monophosphate triethylammonium salt is synthesized in high purity and high quality, with a CAS number of 102747-23-2.Degré de pureté :Min. 95%2'/3'-O-Trinitrophenyl-adenosine-5'-triphosphate triethylammonium salt - 10mM aqueous solution
CAS :2'/3'-O-Trinitrophenyl-adenosine-5'-triphosphate triethylammonium salt - 10mM aqueous solution is a synthetic nucleoside that contains a phosphate group. It is an activator and anti-cancer agent that has been modified to be novel and high quality. This product has been shown to have antiviral, antibacterial, and anticancer properties. 2'/3'-O-Trinitrophenyl-adenosine-5'-triphosphate triethylammonium salt - 10mM aqueous solution is used in the treatment of HIV/AIDS, which may be due to its ability to inhibit viral DNA synthesis.Formule :C16H17N8O19P3Degré de pureté :Min. 95%Masse moléculaire :718.27 g/mol3',5'-O-(Di-tert-butylsilanediyl)uridine
CAS :3',5'-O-(Di-tert-butylsilanediyl)uridine is a novel antiviral agent that is synthesized from uridine and has been shown to be effective against herpes simplex virus. This compound was also shown in vitro to inhibit the replication of human immunodeficiency virus type 1 (HIV-1). 3',5'-O-(Di-tert-butylsilanediyl)uridine binds to single stranded DNA, preventing the synthesis of DNA by the viral enzyme reverse transcriptase. It also inhibits the production of viral proteins by binding to viral RNA polymerase. This drug may also have anticancer activity due to its ability to inhibit ribonucleotide reductase, an enzyme required for DNA synthesis.
Degré de pureté :Min. 95%2-Amino-6-chloro-4-methoxypyrimidine
CAS :2-Amino-6-chloro-4-methoxypyrimidine (2ACMP) is a molecule that has been synthesized by the process of asymmetric synthesis. It is soluble in ethyl formate and has shown to be a strong inhibitor of the enzyme uv absorption, with an inhibition constant of 1.0 x 10 M. 2ACMP has been shown to inhibit molecular processes such as vibrational excitation, molecular modeling, and surface methodology. This molecule also binds to metal hydroxides and can be used for process optimization when combined with solubility data and nutrient solutions.
Formule :C5H6ClN3ODegré de pureté :Min. 95%Masse moléculaire :159.57 g/mol5'-O-DMT-2'-O-hexylphthalimidocytidine
5'-O-DMT-2'-O-hexylphthalimidocytidine is a novel anticancer drug that belongs to the class of nucleosides. It is an analog of cytidine, with a modified phosphoramidate linkage to the 5' carbon atom. This phosphoramidate linkage prevents the spontaneous hydrolysis of 5'-O-DMT-2'-O-hexylphthalimidocytidine, which inhibits DNA and RNA synthesis. The synthetic process for this compound is straightforward and the yield is high. 5'-O-DMT-2'-O-hexylphthalimidocytidine has been shown to be effective against some strains of HIV in vitro and in vivo, as well as some antiviral agents such as herpes simplex virus type 1 (HSV1) and varicella zoster virus (VZV).Formule :C44H46N4O9Degré de pureté :Min. 95%Masse moléculaire :774.28 g/molRSPACER CEP
CAS :RSPACER CEP is a novel synthetic oligonucleotide with anti-cancer and antiviral activity. The product has been shown to inhibit the proliferation of tumor cells in vitro and reduce the production of pro-inflammatory cytokines in macrophages. The product is phosphoramidite, which is an intermediate for the chemical synthesis of DNA. It is synthesized from deoxyribonucleosides, modified nucleosides, and monophosphate nucleotides. RSPACER CEP also has antiviral properties that are mediated by inhibiting viral RNA replication in infected cells through inhibition of viral polymerase.
Formule :C41H59N2O7PSiDegré de pureté :Min. 95%Masse moléculaire :751 g/mol2-Methylaminoadenosine
CAS :2-Methylaminoadenosine is a nucleoside that is the product of the action of adenosine deaminase on 2-aminoadenosine. It is used in diagnostic assays to differentiate between n6-methyladenosine and deoxyadenosine in DNA, RNA, or serum samples. It has been shown to have an interaction with fatty acids and their derivatives and sequences in tissues. In addition, it has been shown to have specificities for cardiac tissue and a flow rate that is constant.Formule :C11H16N6O4Degré de pureté :Min. 95%Masse moléculaire :296.28 g/mol
