Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å
The 2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å is a synthetic, high quality, novel and high purity phosphoramidite that is activated with DMAP. The covalent linkage of the nucleoside to the CPG is made by an amidite coupling reaction. The following compounds have been synthesized on this support: ampicillin, chloramphenicol, gentamicin, kanamycin, neomycin and tetracycline. This product is used in anticancer and antiviral research.Degré de pureté :Min. 95%5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylideneuridine
CAS :5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylideneuridine is a synthetic nucleoside analogue. It has been used as a research tool for studying the activity of the enzyme thymidine phosphorylase, which is involved in the regulation of DNA synthesis. 5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylideneuridine was synthesized by condensing 1,6-dichlorobenzene with 2,3,4,6-tetraiodopyrimidine in the presence of potassium carbonate and zinc chloride. The thermal analysis showed that this compound exhibits high enthalpy and low entropy values. This means that it decomposes into products at high temperatures and has a relatively low reactivity.Formule :C12H14ClIN2O5Degré de pureté :Min. 95%Masse moléculaire :428.61 g/mol2'-Deoxy-N2,N8-di-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite
CAS :2'-Deoxy-N2,N8-di-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite is a novel nucleoside that has shown anticancer activity. It is a modified deoxyribonucleoside with an N2,N8-di-DMF group attached to the 2' position of the ribose and a 5'-O-DMT group at the 8 position of the ribose. The compound binds to DNA and inhibits viral protein synthesis by preventing RNA polymerase from initiating transcription. It also inhibits bacterial DNA gyrase, which results in inhibition of bacterial DNA replication. This product is synthesized using high purity chemical reagents and yields a high quality product that is free of contaminants.Formule :C46H59N10O7PDegré de pureté :Min. 95%Masse moléculaire :895.02 g/mol3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride
3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride is a nucleoside that belongs to the class of diphosphates. It has been shown to be an anticancer agent and is used in the treatment of patients with hematological malignancies. 3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride is synthesized from 5'-deoxyuridine monophosphate and amidites, which are modified phosphoramidites. This compound can be used as a building block for DNA synthesis by incorporating into a growing chain, or as an activator for DNA polymerases. 3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride has been shown to induce apoptosis, or programmed cell death, in cancer cells.Degré de pureté :Min. 95%3'-O-Methyluridine-5'-triphosphate lithium salt - 100 mM in water
CAS :3'-O-Methyluridine-5'-triphosphate lithium salt is a nucleoside that inhibits viral replication and tumor growth. It is a modified form of uridine with an extra methyl group at the 3′ position. The phosphoramidite can be used as an activating reagent for the synthesis of DNA. 3'-O-Methyluridine-5'-triphosphate lithium salt can also be used in the production of antiviral drugs, anticancer drugs, and novel compounds for research purposes.Formule :C10H13N2O15P3Li4Degré de pureté :Min. 98 Area-%Couleur et forme :Clear LiquidMasse moléculaire :521.9 g/mol8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphate sodium salt
CAS :8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphate sodium salt (8CPTcGMP) is a fluorescent compound that is used to study the localization of proteins in living cells. It has been shown to bind to polypeptides that are involved in apoptotic cell death and its binding can be used as an indicator of apoptosis. 8CPTcGMP binds to chaperones, which are proteins that assist protein folding and other cellular processes by preventing misfolding. Fluorescence resonance energy transfer (FRET) between 8CPTcGMP and a fluorophore attached to another molecule can be used to detect the presence of this protein. The genetic code for 8CPTcGMP is ACACTCA.Formule :C16H14ClN5O7PS·NaDegré de pureté :Min. 95%Masse moléculaire :509.79 g/molN6-(4-Methyoxybenzoyl)adenosine
CAS :N6-(4-Methoxybenzoyl)adenosine is an adenine base that is a furanose sugar, with a glycosidic bond. The furanose ring has a phenyl group and an adenine base in the conformation of pyranose. The phenyl ring is in the geometry of chair form and is bonded to the 6' position of the adenosine base. N6-(4-Methoxybenzoyl)adenosine has a glycosidic bond at C1' - C5'. It has an angstrom distance between C1'-C2' and C3'-C5'.
Formule :C18H19N5O6Degré de pureté :Min. 95%Masse moléculaire :401.37 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 1400 Å
N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 1400 Å is a nucleoside that has antiviral activity. It is the monophosphate, ribonucleoside, and diphosphate analog of adenosine. The novel analog N6-benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 1400 Å has been shown to be an effective anticancer drug and also to activate gene expression in cultured cells. This nucleoside can be used in the synthesis of DNA, as well as phosphoramidites for chemical synthesis of deoxyribonucleic acid (DNA).
Degré de pureté :Min. 95%Couleur et forme :PowderN4-Acetyl-2'-deoxy-5'-O-DMT-5-iodocytidine
CAS :N4-Acetyl-2'-deoxy-5'-O-DMT-5-iodocytidine is a synthetic nucleoside that has antiviral and anticancer properties. It is an activator of deoxyribonucleosides and can be used to synthesize DNA, RNA, or other modified nucleosides. This compound is modified with acetyl groups at the 2' position and 5' position of the ribose sugar to increase its stability in biological systems. N4-Acetyl-2'-deoxy-5'-O-DMT-5-iodocytidine has been shown to inhibit viral replication by acting as a monophosphate or diphosphate and inhibiting the synthesis of viral DNA.Formule :C32H32IN3O7Degré de pureté :Min. 95%Masse moléculaire :697.52 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-methyladenosine
CAS :N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-methyladenosine is a nucleoside analog. It is an antiviral and anticancer agent that inhibits the synthesis of RNA by inhibiting the DNA polymerase enzyme. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-methyladenosine has been shown to be active against both DNA and RNA viruses, including herpesviruses. It has also been shown to have anti-inflammatory effects.Formule :C24H33N5O5SiDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :499.64 g/molN4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)-5-methylcytidine
N4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)-5-methylcytidine is an antiviral nucleoside that is a phosphoramidite. It inhibits the synthesis of viral RNA and DNA, as well as the activation of viruses. N4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)-5 methylcytidine is a novel nucleoside analog with anticancer activity and good solubility in organic solvents. This compound has been synthesized by the reaction of 3,4,5,6 tetrahydrobenzo[d]oxazolone with 2’ chloroethylamino 5’ methyl cytidine. The purity of this compound is very high (>98%). The CAS number for this compound is 10Degré de pureté :Min. 95%5’-O-(4-Cyanobenzyl)-2’,3’-di-O-isopropylideneadenosine
CAS :5’-O-(4-Cyanobenzyl)-2’,3’-di-O-isopropylideneadenosine is a monophosphate nucleoside. It is a novel and modified nucleoside with antiviral and anticancer activity. 5'-O-(4-Cyanobenzyl)-2'-,3'-di-O-isopropylideneadenosine is an activator of DNA synthesis and has been shown to be effective against human papilloma virus (HPV), Epstein Barr Virus (EBV), and HIV. This compound also has high purity, CAS No. 1134156-51-6, diphosphate, Deoxyribonucleosides, Activator, High quality, Synthetic, Novel, Nucleosides, Modified that makes it suitable for use in pharmaceuticals.Degré de pureté :Min. 95%2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine
2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine is a nucleoside that is used in the production of DNA and RNA. It is an activator of phosphoramidites, which are used to synthesize oligonucleotides. 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine can be used as an anti-cancer drug and has antiviral activity. It has been shown to inhibit the replication of HIV by interfering with viral enzymes such as reverse transcriptase and integrase. 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine can also be used for the treatment of influenza A virus infections. This drug is highly purified, with a high quality, monophosphate form as well as a diphosphate form. There are no known side effects associated with this product.!--
Formule :C32H30F3N3O8Degré de pureté :Min. 95%Masse moléculaire :641.61 g/mol3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine
CAS :3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is a nucleoside analogue that has antiviral and anticancer activities. It is synthesized by the condensation of orotic acid with 2'-deoxyuridine in the presence of N,N'-dicyclohexylcarbodiimide (DCC). 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is an activator of ribonucleotide reductase, which is an enzyme involved in DNA synthesis and repair. 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is also capable of inhibiting DNA polymerases and RNA polymerases. This drug can be used for treatment against cancer and antiviral infections.Formule :C27H28N2O8Degré de pureté :Min. 95%Masse moléculaire :508.50 g/molLutonarin
CAS :Lutonarin is a naturally occurring compound in the plant Pueraria lobata. It has been shown to have anti-cancer properties and can be used as an alternative to radiation therapy for cancer treatment. Lutonarin is a membrane-hyperpolarizing agent that is able to pass through the cell membrane, leading to membrane hyperpolarization. Lutonarin also inhibits the production of gamma-aminobutyric acid (GABA), which leads to increased cell proliferation and inhibition of root formation. Lutonarin has been found to inhibit enzyme activities, such as glucose monitoring and protocatechuic acid, phenolic acid, and crystalline cellulose degradation. This leads to reduced glucose levels in blood plasma and reduced degradation of polysaccharides in roots.Formule :C27H30O16Degré de pureté :Min. 95%Masse moléculaire :610.5 g/molNicotinamide guanine dinucleotide sodium salt
CAS :Nicotinamide guanine dinucleotide sodium salt is a nucleoside that is the product of the reaction between nicotinamide and guanosine triphosphate. It is an immunosuppressant that binds to CD38, which is expressed on immune cells, to inhibit the activation of T cells by antigen receptors. Nicotinamide guanine dinucleotide sodium salt has been shown to be effective in treating patients with rheumatoid arthritis and ulcerative colitis who have failed treatment with other drugs. This drug also inhibits antibody production by binding to IgG1 antibodies.
Formule :C21H28N7O15P2·xNaDegré de pureté :Min. 95%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :680.43 g/molBiotin-11-cytidine-5'-triphosphate lithium salt - 1mM aqueous solution
Biotin-11-cytidine-5'-triphosphate lithium salt - 1mM aqueous solution is a novel nucleotide analogue that is synthesized by the coupling of a deoxyribonucleoside with a diphosphate. It has antiviral and anticancer activity, and may also be used to treat various types of infections. Biotin-11-cytidine-5'-triphosphate lithium salt - 1mM aqueous solution is an excellent activator of DNA polymerase in vitro, which can be used in the synthesis of DNA or RNA. This product has high purity, as well as monophosphate, diphosphate, and triphosphate forms.Formule :C28H46N7O17P3S·xLiDegré de pureté :Min. 95%Masse moléculaire :877.69 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Sp-oxazaphospholidine
2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Sp-oxazaphospholidine is a DNA synthesis inhibitor. It is modified with a 2'-deoxy-5'-O-dimethoxytrityl group on the 2' position and an N2,N2-(isobutyryl) guanine moiety on the 5' position. This compound inhibits DNA synthesis by forming a covalent bond to the 3' phosphate of DNA. This product is synthesized in high purity and quality. It can be used for anticancer research or as an activator for phosphoramidites for the synthesis of DNA. CAS No.: 63787-03-6Degré de pureté :Min. 95%5'-O-DMT-thymidine 3'-thiophosphoramidite
5'-O-DMT-thymidine 3'-thiophosphoramidite is a nucleoside that is used as a building block for the synthesis of DNA and RNA. The compound is also used to create antiviral drugs, anticancer agents, and novel drugs with antimicrobial properties. The chemical structure of 5'-O-DMT-thymidine 3'-thiophosphoramidite has been modified from the natural ribonucleoside thymidine. This modification prevents the phosphorylation of 5'-O-DMT-thymidine 3'-thiophosphoramidite by cellular kinases, which makes this compound more stable in vivo.Formule :C44H48N3O8PS2Degré de pureté :Min. 95%Masse moléculaire :841.97 g/mol3'-epi-idoxuridine
CAS :3'-Epi-idoxuridine is a nucleoside analog that inhibits viral DNA synthesis. It is an antiviral agent that prevents the synthesis of viral DNA by competitive inhibition with deoxyuridine, which is required for the formation of dTMP. 3'-Epi-idoxuridine inhibits the incorporation of deoxyribonucleotides into HIV-1 and other retroviruses and may be useful in the treatment of AIDS.Formule :C9H11IN2O5Degré de pureté :Min. 95%Masse moléculaire :354.1 g/mol
