Nucléosides

<p>8-Amino-2’-deoxyadenosine (8AAD) is a nucleoside that is used in the laboratory for the analysis of dna duplexes. It stabilizes dna duplexes in an acidic environment, and it can be used to analyze the stability of dna duplexes at neutral pH. 8AAD can also stabilize triplex structures formed by 8AAD, amines, and purines. The orientation of these bases in the triplex structure is important because they can determine which strands are cleaved during hydrolysis.</p>

<p>N6-Benzyladenosine 5'-diphosphate sodium salt is a modified nucleoside that has a high purity, which is suitable for synthesis of DNA or RNA. It can be used in the modification of deoxyribonucleosides, ribonucleosides, and phosphoramidites. N6-Benzyladenosine 5'-diphosphate sodium salt has been shown to have anticancer effects and antiviral effects. This drug also has novel properties such as an ability to inhibit the proliferation of cancer cells.</p>

<p>Thymidine-3',5'-diphosphate disodium salt is an antiviral and anticancer drug. It is a modified nucleoside which is synthesized from thymidine-3',5'-diphosphate and sodium bicarbonate (NaHCO3). This drug inhibits the synthesis of DNA and RNA, thereby inhibiting viral replication. Thymidine-3',5'-diphosphate disodium salt also has an antitumor effect by preventing the production of DNA in tumor cells.</p>

<p>2',3'-O-Isopropylideneinosineis a nucleoside for use in research applications</p>

<p>m-Methoxytopolin riboside is a nucleoside that is a phosphoramidite derivative of the natural nucleoside, topolin riboside. This compound has antiviral and anticancer activities. It inhibits viral DNA synthesis and also induces apoptosis in cancer cells. m-Methoxytopolin riboside is modified with a methoxy group at the 3' position of the sugar moiety. This modification prevents incorporation into DNA and RNA, thereby inhibiting viral replication and inducing apoptosis in cancer cells.</p>

<p>N6-Benzoyl-3-deaza-2'-deoxy-5'-O-DMT-3-methyladenosine 3' is a nucleoside that has been modified to be resistant to the enzymatic degradation by ribonucleases. The phosphoramidite is used in the synthesis of DNA and can be used as an antiviral or anticancer drug. It also acts as a competitive inhibitor of adenosine deaminase, which is an enzyme involved in the metabolism of purines. N6-Benzoyl-3-deaza-2'-deoxy-5'-O-DMT-3 methyladenosine 3' can inhibit viral replication by inhibiting RNA polymerase activity, and it has been shown to have antifungal properties.</p>

<p>Adenosine 3'-monophosphate sodium is a nucleotide that is used as a substrate for enzymes. It has been shown to increase the enzymatic activity of papaverine, litoralis, subtilis, and histidine phosphatase. Adenosine 3'-monophosphate sodium also has protease activity, which can be activated by adding an enzyme preparation containing subtilisin and trypsin. This compound also has a pH optimum of 8.0-9.5 and is active at an alkaline pH of 9.5-10.5. The specific strain of bacteria will determine the optimal pH range for activity, with enterobacter bacterial strains having a maximum range of 6-7 and brevibacterium bacteria strains having a range of 4-6.</p>

<p>2'-O-Methyl-p-thiouridynyl-(3'-&gt;5')-2'-deoxyadenosine is an analog of the nucleoside uridine. It is a potent inhibitor of protein synthesis in cells, and has the potential to be used as a long-term treatment for tuberculosis. 2'-O-Methyl-p-thiouridynyl-(3'-&gt;5')-2'-deoxyadenosine has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) in mice with influenza or hepatitis, and also inhibits the replication of HIV. This drug may also have antibacterial properties due to its ability to inhibit bacterial DNA gyrase and topoisomerase IV. 2'-O-Methyl-p-thiouridynyl-(3'-&gt;5')-2'-deoxyadenosine binds to an antigen on the surface of cells, activating them.</p>

<p>Methyluridine is a derivative of uridine that is used in the synthesis of pyrimidine nucleotides. This drug is also an inhibitor of orotidine 5′-monophosphate decarboxylase, which converts orotic acid to uracil. The conformational properties of methyluridine have been studied and found to be similar to those of other purine derivatives, such as adenine and guanine. In addition, methyluridine has been shown to inhibit the growth of typhimurium and increase the production of uracil in human lymphocytes. Methyluridine is metabolized by hydroxylation in liver microsomes, yielding 6-carboxylic acid.</p>

<p>N6-Benzoyl-2'-deoxy-5'-O-DMT-8-oxoadenosine 3'-CE phosphoramidite is an 8-oxo modified amidite</p>

<p>2-Phenylaminoadenosine (2-PA) is a potent and selective inhibitor of the P2Y receptor. 2-PA has been shown to reduce myocardial infarct size in vivo in mice, which may be due to its ability to inhibit the release of dopamine from the brain. In addition, 2-PA binds to LPS receptors on endothelial cells, reducing the production of proinflammatory cytokines and preventing platelet aggregation. 2-PA also inhibits the activation of toll-like receptor 4 (TLR4) in human monocytes, leading to reduced expression of proinflammatory cytokines and increased expression of anti-inflammatory cytokines.<br>2-PA is an agonist that binds with high affinity to P2Y receptors on erythrocytes. This binding results in decreased adenosine triphosphate (ATP) production by adenosine deaminase, which leads to decreased intracellular calcium levels and inhibition of neutroph</p>

<p>2'-O-Methyluridine-5'-monophosphate triethylammonium salt is a modified nucleoside analogue that is an antiviral agent. It inhibits viral replication by acting as an inhibitor of RNA synthesis and DNA polymerase, which are necessary for the virus to replicate. This compound also has anticancer activity and can be used as a chemotherapeutic agent. 2'-O-Methyluridine-5'-monophosphate triethylammonium salt is synthesized from uracil, phosphoramidite, and triethylamine. It has high purity and high quality with a CAS number of 67624-43-5.</p>

<p>Please enquire for more information about O1-(Dimethoxytrityl)propane-1,3-diol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2'-O-Methyladenosine 5'-monophosphate triethylammonium salt is an antiviral nucleoside that is used in the treatment of hepatitis B and C. It is a modified nucleoside that inhibits the replication of RNA by binding to the enzyme ribonuclease, which plays a vital role in the synthesis of DNA. 2'-O-Methyladenosine 5'-monophosphate triethylammonium salt also has anticancer properties and can inhibit DNA synthesis. This compound is a novel phosphoramidite building block for oligonucleotide synthesis and has been shown to be an activator for deoxyribonucleosides.</p>

<p>Please enquire for more information about 2′-C-Methyl-2′,3′-O-(1-methylethylidene)adenosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-Acetyl-2'-deoxy-2',2'-difluorocytidine is a novel nucleoside analog. It is phosphorylated at the 5' position and converted to a monophosphate by adenylyl cyclase, which is an enzyme that catalyzes the conversion of ATP to cyclic AMP. This nucleoside analog has antiviral activity in vitro and in vivo against HIV-1. It also has been shown to inhibit DNA replication of human cells infected with herpes simplex virus type 1 (HSV-1).</p>

<p>10umol is approx 5mg.2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate is a novel nucleoside phosphorylated on the 5' position</p>

<p>Please enquire for more information about 5'-o-(4,4'-Dimethoxytrityl)-2'-deoxythymidine-3'-(methyl-N,N-diisopropyl)phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>10umol is approximately 5mg.2'-O-(2-Methoxyethyl)adenosine 5'-monophosphate is a nucleoside compound that has been phosphorylated in the 5'-position.</p>

<p>Abacavir 5'-phosphate is a nucleoside analog that inhibits the replication of the herpes virus by covalently binding to the viral DNA polymerase and blocking its ability to polymerize dNTPs. Abacavir 5'-phosphate's anti-viral potency has been shown in vivo using a model with herpes simplex virus, and it has been shown to inhibit viral replication in cell culture. The drug also reacts with cellular components such as proteins, lipids, and nucleic acids, which may lead to drug reactions. Abacavir 5'-phosphate is chemically stable, so it can be subjected to analytical methods without degradation. It is an analog of zidovudine (AZT).</p>