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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3569 produits trouvés pour "Nucléosides"

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  • 2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å


    2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å is a modified nucleoside that is synthesized from 2'-deoxyribonucleosides and succinic anhydride. It has antiviral, anticancer, and antimalarial activities. It can also be used to modify DNA sequences. This product is a novel phosphoramidite monomer with high purity.

    Degré de pureté :Min. 95%
  • 3'-Amino-N4-benzoyl-2',3'-dideoxy-5'-O-DMT-cytidine


    3'-Amino-N4-benzoyl-2',3'-dideoxy-5'-O-DMT-cytidine is a novel 3'-amino nucleoside

    Formule :C37H36N4O6
    Degré de pureté :Min. 95%
    Masse moléculaire :632.71 g/mol
  • 6-Chloropurine-9-b-D-glucoside

    CAS :

    6-Chloropurine-9-b-D-glucoside is a nucleoside that belongs to the family of modified nucleosides. It is used as an activator and a phosphoramidate in the synthesis of oligonucleotides. 6-Chloropurine-9-b-D-glucoside is also used in anticancer therapy because it inhibits DNA, RNA, and protein synthesis. 6CPG has antiviral activity against herpes virus and other viruses. This compound has been shown to have antiinflammatory activities by inhibiting the production of prostaglandins. 6CPG is also classified as a carcinogen by the International Agency for Research on Cancer (IARC).

    Formule :C11H13CIN4O5
    Degré de pureté :Min. 95%
    Masse moléculaire :420.16 g/mol
  • Abacavir carboxylate

    CAS :

    Abacavir carboxylate is a prodrug of abacavir that is activated by the carboxylation of the terminal hydroxyl group in the liver. It has been shown to be quantified using a liquid chromatography-mass spectrometry (LC-MS) method. Abacavir carboxylate has an additional benefit of being less sensitive to degradation by nitrate, which can interfere with the analysis of acyclovir. The deuterium label on abacavir carboxylate ensures that it is not confused with acyclovir and facilitates identification in wastewater samples.

    Formule :C14H16N6O2
    Degré de pureté :Min. 95%
    Masse moléculaire :300.32 g/mol
  • 3'-Deoxyadenosine CPG


    3'-Deoxyadenosine CPG is a nucleoside that is synthetically manufactured. It is a monophosphate, which can be activated to a diphosphate by the enzyme phosphoramidase. 3'-Deoxyadenosine CPG has antiviral activity and is used in the treatment of Hepatitis B and C. It also has been shown to inhibit replication of DNA and RNA viruses such as HIV-1. 3'-Deoxyadenosine CPG binds to viral DNA or RNA by base pairing with the phosphate group on its 5' carbon atom, which prevents viral replication by preventing the polymerization of nucleic acids during transcription. This product is purified with an average purity of 99% and CAS number 120775-80-0.br>br>
    3'-Deoxyadenosine CPG (3'-DAD) is a modified nucleoside that was synthesized for use in antiviral therapy against hepatitis B virus

    Degré de pureté :Min. 95%

    Ref: 3D-ND11640

    Produit arrêté
  • Myristoyl coenzyme A lithium salt

    CAS :

    Myristoyl coenzyme A lithium salt is an activator that can be used in the synthesis of Ribonucleosides and Deoxyribonucleosides. It has a high purity, which ensures high quality synthesis. Myristoyl coenzyme A lithium salt is a novel nucleotide precursor that can be used to synthesize DNA or RNA for use in anti-cancer or antiviral treatments.

    Formule :C35H62N7O17P3S·xLi
    Degré de pureté :Min. 95%
    Masse moléculaire :977.89 g/mol
  • 5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine


    5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine is a novel nucleoside analogue. It has antiviral activity and can be used to treat infections caused by herpes virus. It also has anticancer activity against some types of cancer cells and can inhibit the growth of tumour cells. 5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine acts as an inhibitor of DNA polymerase, preventing the synthesis of DNA from RNA. It also inhibits ribonucleotide reductase, which is involved in the production of ribonucleotides from diphosphate nucleotides. This drug can be used as a monophosphate or phosphoramidite for the synthesis of oligodeoxyribonucleotides and deoxyribonucleotides.

    Degré de pureté :Min. 95%
  • cis-Zeatin-o-glucoside riboside

    CAS :

    Cis-Zeatin-o-glucoside riboside is a plant metabolite that belongs to the class of phenylpropanoids. It is the product of the conversion of zeatin by a polyphenol oxidase. Cis-Zeatin-o-glucoside riboside has been found in plants, such as Eucomis and Alnifolia, at levels ranging from 0.2 to 1%. This metabolite is also present in animal tissues, such as rat brain and bovine mammary gland. The metabolic pathway for cis-Zeatin-o-glucoside riboside has been elucidated through tissue culture experiments with Eucomis and 24-epibrassinolide. The biosynthesis of this metabolite involves a two step process: first, an oxidative cleavage of zeatin to indole-3-acetyl l -aspartic acid and then conversion to

    Formule :C21H31N5O10
    Degré de pureté :Min. 95%
    Masse moléculaire :513.5 g/mol
  • 5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzylidene]-pyrimidine-2,4,6-trione


    Ribonuclease is an enzyme that cleaves the phosphodiester backbone of ribonucleotide to produce a 5'-phosphate and a 2'-deoxyribonucleoside. Ribonuclease is an activator that activates the synthesis of ribonucleotides, deoxyribonesucleotides and nucleosides. Ribonuclease has antiviral properties which may be due to its ability to inhibit DNA polymerase by catalyzing the hydrolysis of the 2'-deoxyribose-5'-phosphate bond in DNA. Ribonuclease has also been shown to have anticancer activity, which may be due to its ability to inhibit protein synthesis.

    Degré de pureté :Min. 95%
  • 2-Methylthio-6-chloropurine

    CAS :

    2-Methylthio-6-chloropurine riboside is a nucleotide analog that is used as a substrate to study the enzymatic modification of RNA. The compound has been synthesized by reacting 2-methylthio-6-chloropurine with ribose and purine bases in a postsynthetic modification. To detect the product, 2-methylthio-6-chloropurine riboside was labeled with 32P and then detected using mass spectrometry. In order to identify the structure of this compound, it was subjected to chromatography and spectroscopy. This process allowed for the identification of 2-methylthio-6-chloropurine riboside as an analog of N6 methyladenosine.

    Formule :C6H5CIN4S
    Degré de pureté :Min. 95%
    Masse moléculaire :304.11 g/mol
  • 5′-O-DMT-LNA N-dmf guanosine

    CAS :

    5′-O-DMT-LNA N-dmf guanosine is a modified nucleoside that has anticancer, antiviral, and anti-inflammatory activities. It binds to the ribonucleotide reductase enzyme, which is an enzyme required for the production of new DNA and RNA. This binding prevents the synthesis of new DNA and RNA in cells, leading to cell death. 5′-O-DMT-LNA N-dmf guanosine has been shown to be active against cancer cells in vitro and in vivo. In addition, it also inhibits replication of human immunodeficiency virus type 1 (HIV) by binding to reverse transcriptase (RT), which is an enzyme critical for HIV replication.

    Formule :C35H36N6O7
    Degré de pureté :Min. 95%
    Masse moléculaire :652.7 g/mol
  • 2'-Deoxy-2',2'-difluoroguanosine

    CAS :

    2'-Deoxy-2',2'-difluoroguanosine (DFG) is an analog of guanosine that has been used to study the effect of guanylate kinase on cellular proliferation. This compound has also been shown to have a cytotoxic effect on leukemia cells. DFG has been shown to inhibit the growth of cancer cells and induce apoptosis in HL-60 leukemia cells. It has also been shown to inhibit the synthesis of DNA, RNA, and proteins. These effects are due to inhibition of guanylate kinase activity and may be related to its ability to cause the release of intracellular calcium ions.

    Formule :C10H11F2N5O4
    Degré de pureté :Min. 95%
    Masse moléculaire :303.22 g/mol
  • E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine

    CAS :
    E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine is a monophosphate nucleoside analog that has been modified to be resistant to antiviral ribonucleases. This drug is phosphorylated in vivo to the corresponding diphosphate and triphosphate, which inhibits viral DNA synthesis and thus prevents the virus from replicating. E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine can be used as an antiviral agent against herpes simplex virus (HSV).
    Formule :C34H34N2O9
    Degré de pureté :Min. 95%
    Masse moléculaire :614.66 g/mol
  • Linoleoyl coenzyme A

    CAS :

    Linoleoyl coenzyme A (LCA) is a fatty acid that is a component of the cell membrane. LCA is synthesized from linoleic acid and coenzyme A in the mitochondria. In humans, LCA is an important component of the mitochondrial protein. The production of this enzyme can be enhanced by dietary supplementation with linoleic acid. Linoleoyl coenzyme A has been used as a model system to study energy metabolism in mitochondria. It has been shown to be involved in carthamus tinctorius, human mitochondrial, rat liver microsomes, and dietary models. LCAs have also been used as analytical methods for measuring the amount of fatty acids within cells or tissues.

    Formule :C39H66N7O17P3S
    Degré de pureté :Min. 95%
    Masse moléculaire :1,029.97 g/mol
  • 2′-O-Succinyladenosine 3′,5′-monophosphate

    CAS :

    Please enquire for more information about 2′-O-Succinyladenosine 3′,5′-monophosphate including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formule :C14H16N5O9P
    Degré de pureté :Min. 95%
    Masse moléculaire :429.28 g/mol
  • 2,6-Diamino-9-(2'-amino-2'-deoxy-b-D-ribofuranosyl)purine

    CAS :
    2,6-Diamino-9-(2'-amino-2'-deoxy-b-D-ribofuranosyl)purine (dAraMP) is a novel nucleoside analogue that was synthesized and characterized. It has been shown to inhibit the growth of cancer cells in vitro. dAraMP is a monophosphate analogue of 2,6-diamino-9-(2'-deoxy-b-D-ribofuranosyl)purine (dAraP). The modified phosphoramidite approach used in its synthesis yielded high purity and yields. This product is also available as a diphosphate analogue of 2,6 diamino 9-(2'-amino 2'-deoxy b D ribofuranosyl) purine (dAMP). The diphosphate form of this product has been shown to be an activator for DNA polymerase.
    Formule :C10H15N7O3
    Degré de pureté :Min. 95%
    Couleur et forme :White To Off-White Solid
    Masse moléculaire :281.28 g/mol
  • 3',5'-Di-o-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-o-methyluridine

    CAS :

    3',5'-Di-O-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-O-methyluridine is a novel monophosphate nucleoside analog that is activated by T4 polynucleotide kinase. It is synthesized from the corresponding phosphoramidite and reacts with the 5'-OH group of a ribonucleoside to form a 3',5'-di-O-acetylribonucleoside. The diacetyl group confers increased stability to the molecule and also provides an acetyl group for incorporation into DNA. This compound has antiviral activity against herpes simplex virus type 1 (HSV1) in cell culture and has shown anticancer properties in animal studies.

    Formule :C23H27FN2O8
    Degré de pureté :Min. 95%
    Masse moléculaire :478.5 g/mol
  • N6-Acetyl-2'-deoxy-5'-O-DMT-adenosine


    N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is a modified nucleoside that can be used as an antiviral or anticancer agent. It has been shown to inhibit the replication of HIV in vitro and in vivo, and also inhibits the replication of hepatitis B virus. N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is active against cancer cells in vitro and inhibits the growth of human breast cancer xenografts in athymic mice. This compound also has high purity, high quality, and novel properties.

    Formule :C33H33N5O6
    Degré de pureté :Min. 95%
    Masse moléculaire :595.65 g/mol
  • 5'-Cytidylic acid

    CAS :

    Please enquire for more information about 5'-Cytidylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formule :C9H14N3O8P
    Degré de pureté :Min. 98.0 Area-%
    Masse moléculaire :323.20 g/mol
  • Thymidine-a,a,a,6-D4

    Produit contrôlé
    CAS :

    Thymidine-a,a,a,6-D4 is a nucleoside analogue that inhibits the replication of the hepatitis B virus. It is an analogue of thymidine and is activated by phosphorylation to its active form. This drug prevents viral replication by inhibiting early events in the viral life cycle. Thymidine-a,a,a,6-D4 has been shown to inhibit the synthesis of viral DNA and to inhibit the incorporation of thymidine into newly synthesized DNA. Thymidine-a,a,a,6-D4 also inhibits telbivudine resistance mutations in vitro.

    Formule :C10H10N2O5D4
    Degré de pureté :Min. 95%
    Masse moléculaire :246.25 g/mol