Nucléosides

<p>DMF functionalised 2'-O-methyladenosine</p>

<p>3'-O-Methylcytidine 5'-triphosphate lithium salt is an antiviral agent that inhibits the synthesis of RNA by inactivating the enzyme ribonuclease. The compound has been shown to be effective against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). 3'-O-Methylcytidine 5'-triphosphate lithium salt is a novel nucleoside analogue that can be used as a phosphoramidite building block for DNA synthesis. It is also a high quality synthetic product with high purity and high purity.</p>

<p>Cytidine 5'-diphosphoglycerol disodium salt is a modified nucleotide that belongs to the group of phosphoramidites. It is a cytidine derivative with a 2-hydroxymethylene bridge, which makes it resistant to degradation by cytidine deaminase and therefore enhances its anticancer activity. Cytidine 5'-diphosphoglycerol disodium salt has been shown to inhibit the growth of cancer cells in vitro and in vivo models, as well as inhibit viral replication. Cytidine 5'-diphosphoglycerol disodium salt is stable at high temperatures and can be used for activation of DNA synthesis in vitro. This product has not been tested on animals or humans and should not be taken internally.</p>

<p>Please enquire for more information about Long trebler phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Octanoyl coenzyme A lithium salt hydrate (OCCA) is a metabolite of octanoic acid, which is formed by the oxidation of fatty acids. OCCA has been shown to have relevance in the metabolism of fatty acids, as it can be conjugated with other molecules and transported into cells. This compound has been detected in human liver tissues and was found to be metabolized by primary rat hepatocytes in vitro. The metabolic pathway of OCCA is not yet fully understood, but it has been investigated in vivo studies.</p>

<p>Base labile TFA protected deoxyguanosine</p>

<p>Lauroyl coenzyme A potassium salt is a potent inhibitor of fatty acid synthase. It has the ability to inhibit the enzyme activity of fatty acid synthase in vitro, which belongs to the class of irreversible inhibitors. Lauroyl coenzyme A potassium salt inhibits the synthesis of fatty acids by inhibiting the enzyme activity of fatty acid synthase. This inhibitor also reversibly inhibits other enzymes with a similar mechanism, such as acetyl-coenzyme A carboxylase and phosphatidate phosphohydrolase. The reaction mechanism can be understood through titration calorimetry studies, demonstrating that lauroyl coenzyme A potassium salt binds to the active site of these enzymes and blocks access to substrates. The binding affinity is higher for wild type strains than for mutant strains, which may be due to differences in protein structure or other factors. Lauroyl coenzyme A potassium salt has been shown to have no effect on wild-type strains but inhibits polymer</p>

<p>Please enquire for more information about Doubler phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2'-Deoxy-5-fluorouridine-5'-triphosphate sodium salt - 100 mM solution in water is a nucleotide analog that inhibits the synthesis of RNA. It is used for the treatment of cancer. This agent binds to DNA and prevents the formation of RNA by inhibiting the enzyme ribonucleotide reductase. 2'-Deoxy-5-fluorouridine-5'-triphosphate sodium salt - 100 mM solution in water also has a perchloric acid component, which may be responsible for its haematopoietic effects.</p>

<p>N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-thiophosphoramidite is a modified phosphoramidite that can be used to synthesize DNA oligomers. The nucleoside is an antiviral and antitumor agent. It is also used to inhibit the replication of RNA by inhibiting the activity of DNA polymerase. N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-thiophosphoramidite has novel properties that have not been seen in any other nucleosides. This product is for research use only, not for diagnostics or therapeutic purposes.</p>

<p>Nucleobase functionalised deoxynucleoside</p>

<p>2',3'-Dehydro-5'-O-tritylthymidine is an anticancer compound, which is a novel nucleoside phosphoramidite. It is synthesized from thymidine in two steps: first, the 2',3'-dideoxyribose phosphate moiety is prepared by reacting 2',3'-dideoxyribose with chloroacetic acid in the presence of triethylamine, followed by reaction with trityl chloride to form the 5' position of the thymidine. 2',3'-Dehydro-5'-O-tritylthymidine has been shown to inhibit DNA synthesis and antiviral activity.</p>

<p>2'-Deoxy-5'-O-DMT-5-acetoxymethyluridine 3'-CE phosphoramidite is a novel nucleoside analogue with anticancer activity. It is synthesized from 2'-deoxy-5'-O-DMT-5-acetoxymethyluridine and 3'-chloroethyl phosphate. The compound has been shown to inhibit DNA, RNA, and protein synthesis in vitro, as well as to induce apoptosis in human cancer cell lines. 2'-Deoxy-5'-O-DMT-5-acetoxymethyluridine 3'-CE phosphoramidite is a modified nucleoside that can be used in the production of oligonucleotides for use in gene therapy.</p>

<p>2,2'-Anhydro-L-thymidine is an antiviral, anticancer agent and a synthetic nucleoside. It is a monophosphate that was first synthesized in 1967 and has been used as a potential antiviral agent. 2,2'-Anhydro-L-thymidine has been shown to be effective against the herpes simplex virus type 1 (HSV1). However, it does not inhibit viral nucleic acid synthesis or viral protein synthesis. It also does not inhibit the growth of tumor cells in culture.</p>

<p>4-Thiothymidine-5'-triphosphate lithium salt - 100mM aqueous solution is thio-base modified thymidine nucleotide</p>

<p>Methylglyoxal (MGO) is a reactive byproduct formed by several metabolic precursors notably glycolysis. dG-MGO is therefore a useful marker to in monitoring various glycation pathways</p>

<p>Please enquire for more information about 2’-Deoxy-N2-DMF-2’-fluoroguanosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Bromo substituted deoxyadenosine</p>

<p>7-Deaza-2'-deoxy-7-ethynyladenosine is a fluorescent analog of adenosine that has been synthesized to be used as an antimicrobial agent. This compound has shown to be effective against both Gram-positive and Gram-negative bacteria, including methicillin resistant Staphylococcus aureus and Escherichia coli. 7DDAE is also able to inhibit the growth of fungus and yeast, such as Candida albicans. This drug has been shown to have no cytotoxic effects on mammalian cells at concentrations up to 50 μM. 7DDAE has been found to be very photostable in solution, which means it does not degrade when exposed to light.</p>

<p>5-Fluorouridine-5'-diphosphate sodium salt is a nucleoside analog that inhibits the synthesis of RNA and DNA. It is used to treat cancer, as well as opportunistic infections, such as cryptococcal disease. 5-Fluorouridine-5'-diphosphate sodium salt binds to the enzyme thymidylate synthase and prevents it from synthesizing dTMP, which is needed for DNA synthesis. This drug also has been shown to be effective against monoclonal antibodies in mice with cancer. 5-Fluorouridine-5'-diphosphate sodium salt may also be useful in gene therapy for cancer treatment. This drug can be taken up by cells where it is converted into uracil, which inhibits protein synthesis by competing with the natural substrate tRNA for binding sites on ribosomes.</p>