Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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2'-Deoxy-5'-O-pixylinosine
2'-Deoxy-5'-O-pixylinosine is a nucleoside that is structurally similar to the natural nucleosides. It is modified with an o-pixyl group at the 2' position of the sugar moiety and contains a phosphate group at the 5' position of the sugar moiety. 2'-Deoxy-5'-O-pixylinosine has antiviral, anticancer, and high purity properties due to its ability to inhibit viral DNA polymerases. This compound has been shown to be active against a broad spectrum of viruses including HIV and herpes simplex virus types 1 and 2 (HSV1 and HSV2). This compound is also able to inhibit tumor growth in vitro.Formule :C30H26N4O4Degré de pureté :Min. 95%Masse moléculaire :506.57 g/mol(R)-N-(2,3-Dihydro-1H-indenyl)adenosine
CAS :(R)-N-(2,3-Dihydro-1H-indenyl)adenosine is a purine nucleoside with the attachment of a 2,3-dihydro-1H-indenyl group via a nitrogen atom. This adenosine-based product can be used for research purposesFormule :C19H21N5O4Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :383.4 g/mol5-(Cyanomethyl)-uridine
CAS :5-(Cyanomethyl)-uridine (5-CMU) is a monophosphate nucleoside that is synthetically derived from uracil. This nucleoside has antiviral activity and can be used to treat infections caused by the herpesviridae family, such as herpes simplex virus type 1 and 2. 5-CMU is modified with cyanomethyl groups on the ribose moiety. It is also a phosphoramidite building block for DNA synthesis and can be used in the preparation of oligonucleotides. The CAS number for 5-CMU is 58479-73-5.Formule :C11H13N3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :283.24 g/mol2'-Deoxy-5'-O-tritylinosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-tritylinosine 3'-CE phosphoramidite is an anticancer drug that inhibits the growth of cancer cells. It is a modified nucleoside that is synthesized by reacting 2'-deoxy-5'-O-tritylinosine with a phosphoramidite. This product can be used for the synthesis of DNA, RNA and deoxyribonucleic acid (DNA).Formule :C38H43N6O5PDegré de pureté :Min. 95%Masse moléculaire :694.78 g/mol5,6-Dihydro-5-azacytidine acetate
5,6-Dihydro-5-azacytidine acetate is a monophosphate nucleoside that is used in the synthesis of DNA and RNA. It is an antiviral agent that inhibits the synthesis of DNA by preventing the conversion of deoxyribonucleotides to diphosphates. 5,6-Dihydro-5-azacytidine acetate has been found to have anticancer properties and is used in cancer treatment. This chemical also has a high purity and quality, making it a suitable reagent for use in phosphoramidite coupling reactions for oligonucleotide synthesis. 5,6-Dihydro-5-azacytidine acetate has been shown to be active against a variety of human tumor cell lines, including leukemia cells.Formule :C10H17N4O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :305.26 g/mol5-Methoxycarbonylmethyl-2-thiouridine
CAS :Nucleoside functionalised on the baseFormule :C12H16N2O7SDegré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :332.33 g/molN3-Methyl-2'-O-methyluridine
CAS :2'-O-methyluridine is an antiviral nucleoside that is used as a phosphoramidite in the synthesis of oligonucleotides. It has been shown to inhibit viral replication, and has been found to be effective in treating HIV-1 by inhibiting reverse transcriptase. N3-Methyl-2'-O-methyluridine also inhibits DNA synthesis and cell proliferation, and may be useful for the treatment of cancer. This modified nucleoside has been synthesized from uracil and contains a methyl group at the 3' position. The methyl group prevents 2'-O-methyluridine from being activated by cellular thymidylate synthase, which normally converts deoxyribonucleotides into ribonucleotides. This novel nucleotide has not yet been used in clinical trials but it may provide an alternative to other drugs used for cancer treatments.
Formule :C11H16N2O6Degré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :272.25 g/mol5'-O-Tritylthymidine
CAS :5'-O-Tritylthymidine is a nucleoside that is found in human mitochondrial DNA. It is synthesized from uridine by the enzyme thymidylate synthase and can be converted to thymine by the enzyme thymidine phosphorylase. 5'-O-Tritylthymidine has been shown to inhibit cancer cell growth, but its mechanism of action is not clear. It may inhibit xylene production. 5'-O-Tritylthymidine also causes an increase in p53 activity, which may lead to apoptosis of cancer cells.Formule :C29H28N2O5Degré de pureté :Min. 95%Masse moléculaire :484.54 g/mol2'-C-Methylguanosine
CAS :2'-C-Methylguanosine is a synthetic nucleoside analog of guanosine, modified at the 2'-carbon of the ribose sugar with a methyl group. This modification changes the molecule's biological behavior, making it potential useful in antiviral research and biochemical studies, especially those involving RNA synthesis.Formule :C11H15N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :297.27 g/mol1-(Arabinofuranosyl)-5-azidomethyluracil
CAS :1-(Arabinofuranosyl)-5-azidomethyluracil (AFAU) is a novel nucleoside that is synthesized by the reaction of 5-azido-1-(2'-deoxyribofuranosyl) uracil with phosphoramidite. The synthesis of this nucleoside has been used as a model for the synthesis of other deoxyribonucleosides. AFAU is an activator of ribonucleotide reductase and has shown activity against DNA and RNA viruses, such as influenza virus, herpes simplex virus type 1, and human immunodeficiency virus type 1.Degré de pureté :Min. 95%N6-Benzoyl-9-(3'-O-Deoxy-3'-fluoro-b-D-xylofuranosyl)adenine
N6-Benzoyl-9-(3'-O-Deoxy-3'-fluoro-b-D-xylofuranosyl)adenine is a novel compound that was synthesized in order to improve the activity of adenine. It has been shown to be an effective anticancer agent and antiviral agent in vitro. This drug has also been shown to be effective against herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, and HIV. N6-Benzoyl-9-(3'-O-Deoxy-3'-fluoro-b-D-xylofuranosyl)adenine is a ribonucleoside that binds to DNA and inhibits the synthesis of RNA. The phosphoramidites were synthesized with high purity and high quality. CAS Number: 51401061Degré de pureté :Min. 95%2'-Deoxycytidine-5'-triphosphate trisodium salt
CAS :2'-Deoxycytidine-5'-triphosphate trisodium salt is an activator that has been shown to exhibit anticancer and antiviral activities. It is a novel nucleoside phosphoramidite that is used in the synthesis of DNA, RNA, and other nucleic acids. 2'-Deoxycytidine-5'-triphosphate trisodium salt has been modified by substituting the oxygen atom for a sulfur atom at the 5' position of the sugar moiety. This change makes it resistant to degradation by ribonucleases. 2'-Deoxycytidine-5'-triphosphate trisodium salt has also been shown to act as an inhibitor of human telomerase activity.Formule :C9H13N3O13P3Na3Degré de pureté :(%) Min. 85%Couleur et forme :PowderMasse moléculaire :533.1 g/molCytidyl-3'-5'-guanosine ammonium
CAS :Cytidyl-3'-5'-guanosine ammonium salt is a modified nucleoside that has antiviral and anticancer properties. It is synthetically made by modifying the phosphate groups of cytidine and guanosine with phosphoramidites. Cytidyl-3'-5'-guanosine ammonium salt has been shown to activate protein kinase C, which may be related to its anticancer activity.Formule :C19H25N8O12PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :588.42 g/mol5’-O-Acetyl-5-acetyloxymethyluridine
CAS :5’-O-Acetyl-5-acetyloxymethyluridine is an activated nucleoside that is a phosphoramidite. It can be used in the synthesis of oligonucleotides and has antiviral, anticancer, and antiretroviral activities. This product is a novel compound that can be used to synthesize high quality deoxyribonucleosides and diphosphate ribonucleosides. 5’-O-Acetyl-5-acetyloxymethyluridine is an activator for DNA polymerases and RNA polymerases with a high degree of purity.Formule :C14H18N2O9Degré de pureté :Min. 95%Masse moléculaire :358.3 g/mol3’-Deoxy-5-fluoro-3’-methyluridine
CAS :3’-Deoxy-5-fluoro-3’-methyluridine is a nucleoside that has antiviral and anticancer properties. It is synthesized from 5-fluorouracil, which is a prodrug that is activated by 3’-deoxy-5-fluoro-3’-methyl uridine to produce 5′,6′ difluorodeoxyadenosine. This compound can be used in the treatment of hepatitis B virus and hepatitis C virus infections. 3’-Deoxy-5-fluoro-3’ methyluridine has also been shown to inhibit the growth of cancer cells in vitro.Degré de pureté :Min. 95%7-Deaza-2'-deoxy-6-methoxyguanosine
CAS :7-Deaza-2'-deoxy-6-methoxyguanosine is a modified nucleoside and antiviral agent. It has been shown to inhibit the synthesis of DNA, RNA and protein in cells infected with the herpes simplex virus (HSV). 7-Deaza-2'-deoxy-6-methoxyguanosine is also an anticancer agent that has been shown to inhibit tumor growth in animal models. This compound is synthesized by phosphoramidite chemistry and is a novel precursor for the preparation of modified DNA and RNA. The purity of this product is greater than 98%.Formule :C12H16N4O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :280.29 g/mol5'-Amino-5'-deoxythymidine
CAS :5'-Amino-5'-deoxythymidine is a nucleoside that is structurally related to thymidine. It has been shown to be a substrate for fatty acid synthase, which is a key enzyme in the synthesis of membrane lipids. 5'-Amino-5'-deoxythymidine has been shown to induce tumorigenesis in mouse bladder carcinoma cells. This compound also does not form stable complexes with DNA duplexes and can inhibit uptake of thymidylate into cells by competitive inhibition. 5'-Amino-5'-deoxythymidine binds to the cell surface and acts as an antibody response modifier.Formule :C10H15N3O4Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :241.24 g/mol5-Hydroxymethyl-2’-β-C-methyluridine
CAS :5-Hydroxymethyl-2’C-methyluridine is a modified nucleoside that is an activator of cellular DNA synthesis. It is a synthetic compound that has been shown to be active against cancer cells in vitro. 5-Hydroxymethyl-2’C-methyluridine has also been used to inhibit the replication of various viruses, including herpes simplex virus type 1 and 2, cytomegalovirus, and human immunodeficiency virus type 1. This drug was shown to be safe and effective in clinical trials for the treatment of HIV/AIDS patients with no adverse side effects.Formule :C11H16N2O7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :288.25 g/mol3'-Azido-3'-deoxythymidine 5'-monophosphate sodium salt
CAS :3'-Azido-3'-deoxythymidine 5'-monophosphate sodium salt is a synthetic nucleoside that is structurally related to thymidine. It has antiviral and anticancer properties, as well as the potential for use in gene therapy. 3'-Azido-3'-deoxythymidine 5'-monophosphate sodium salt is active against herpes simplex virus type 1 (HSV-1) and HSV-2, human immunodeficiency virus type 1 (HIV-1), human papillomavirus types 16 and 18 (HPV), Epstein Barr Virus (EBV), and cytomegalovirus (CMV). 3'-Azido-3'-deoxythymidine 5'-monophosphate sodium salt inhibits the production of HIV by preventing the viral reverse transcriptase from synthesizing DNA from RNA.Formule :C10H13N5NaO7PDegré de pureté :Min. 95%Masse moléculaire :369.23 g/molGuanosine 3',5'-cyclic monophosphate sodium salt
CAS :Guanosine 3',5'-cyclic monophosphate sodium salt (cGMP) is a cyclic nucleotide that is involved in the regulation of many cellular processes. It binds to specific guanine nucleotide-binding proteins (G proteins) and activates protein kinase A, which regulates glucose metabolism and energy production. cGMP also affects neuronal death, axonal growth, and bowel disease by acting as a cyclase inhibitor or activating the immune system. It has been shown to reduce the severity of infectious diseases such as HIV and malaria by activating the immune system.Formule :C10H11N5NaO7PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :367.19 g/mol
