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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3567 produits trouvés pour "Nucléosides"

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  • 2'-Deoxy-L-adenosine

    CAS :
    <p>2'-Deoxy-L-adenosine is an adenosine analogue that has been shown to inhibit the growth of tumor cells in mice. The mechanism of this inhibition is not well understood, but it is thought that 2'-deoxy-L-adenosine inhibits the adenosine A3 receptor and blocks the activation of toll-like receptors. This drug also has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. It has been used as a model system for studying cellular responses to DNA damage caused by ultraviolet radiation. 2'-Deoxy-L-adenosine also has been shown to have a cytotoxic effect on human HL60 cells, which is mediated by nuclear DNA fragmentation.</p>
    Formule :C10H13N5O3
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Off-White Powder
    Masse moléculaire :251.25 g/mol

    Ref: 3D-ND04246

    1g
    336,00€
    2g
    550,00€
    5g
    1.067,00€
    10g
    1.920,00€
    500mg
    200,00€
  • 2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite


    <p>2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is a novel nucleoside analog that has been synthesized to have the same chemistry as 2,3'-dideoxycytidine 5'-C phosphoramidite. It has antiviral and anticancer properties. This compound can be used in the synthesis of oligonucleotides for DNA sequencing and for gene therapy.<br>2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is not toxic to normal cells, but it inhibits replication of viruses such as HIV and herpes simplex virus.</p>
    Formule :C25H32N5O5P
    Degré de pureté :Min. 95%
    Masse moléculaire :513.54 g/mol

    Ref: 3D-PA09083

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  • N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine

    CAS :
    <p>N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine is a cytosine analog with high affinity for the T cell receptor. It can be used to generate antibodies against cytosine and as a screening tool for plasmon resonance.</p>
    Formule :C32H32FN3O7
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :589.61 g/mol

    Ref: 3D-NA06052

    5g
    291,00€
    10g
    437,00€
    25g
    806,00€
    50g
    1.193,00€
    100g
    1.952,00€
  • N6-Dimethyl-3’-b-C-methyladenosine

    CAS :
    <p>N6-Dimethyl-3’-b-C-methyladenosine is a novel nucleoside analog that has antiviral and anticancer properties. It is a phosphoramidite, which can be used as an activator for the synthesis of modified oligonucleotides. N6-Dimethyl-3’-b-C-methyladenosine has been shown to activate ribonucleosides and deoxyribonucleosides in vitro. This compound also has anticancer properties, which may be due to its ability to act as an activator in the synthesis of DNA.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND163082

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    À demander
  • 1'-13CCytidine

    CAS :
    <p>Please enquire for more information about 1'-13CCytidine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formule :CC8H13N3O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :244.21 g/mol

    Ref: 3D-NC34303

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  • 5'-O-p-Anisoyl-D3-thymidine

    Produit contrôlé

    <p>5'-O-p-Anisoyl-D3-thymidine is a nucleoside analogue that is used in antiviral and anticancer treatments. It is synthesized by the condensation of 3,4-dihydroxyacetophenone with 2,6-diaminopurine followed by phosphorylation of the 5' hydroxyl group. This product has been shown to be an activator of both DNA polymerase and RNA polymerase. In addition, it can inhibit the production of viral proteins such as HIV protease without affecting protein synthesis in mammalian cells. It also inhibits cancer cell growth by stopping DNA replication at the G2 phase.<br>5'-O-p-Anisoyl-D3-thymidine has been shown to be highly purified and can be used for research purposes. This product may have a CAS number but it will not be listed on this website due to company policy.</p>
    Formule :C18H17N2O7D3
    Degré de pureté :Min. 95%
    Masse moléculaire :379.38 g/mol

    Ref: 3D-NA08692

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    À demander
  • 5'-Amino-5'-deoxythymidine

    CAS :
    <p>5'-Amino-5'-deoxythymidine is a nucleoside that is structurally related to thymidine. It has been shown to be a substrate for fatty acid synthase, which is a key enzyme in the synthesis of membrane lipids. 5'-Amino-5'-deoxythymidine has been shown to induce tumorigenesis in mouse bladder carcinoma cells. This compound also does not form stable complexes with DNA duplexes and can inhibit uptake of thymidylate into cells by competitive inhibition. 5'-Amino-5'-deoxythymidine binds to the cell surface and acts as an antibody response modifier.</p>
    Formule :C10H15N3O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :241.24 g/mol

    Ref: 3D-NA06395

    1g
    1.515,00€
    50mg
    254,00€
    100mg
    400,00€
    250mg
    723,00€
    500mg
    1.047,00€
  • 4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

    CAS :
    <p>4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a nucleoside monophosphate that is used as an antiviral agent. It inhibits the synthesis of viral DNA and RNA by inhibiting the activity of enzymes needed for nucleotide synthesis. 4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine has shown anticancer properties in vitro against human colon cancer cells. This drug has been shown to inhibit the growth of tumor cells with high expression levels of cyclin D1 and low levels of p27 (a cell cycle regulatory protein).</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND162980

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  • N2,N2-Dimethylguanosine

    CAS :
    <p>N2,N2-Dimethylguanosine is a purine nucleoside that is found in human serum. It belongs to the group of purines and has been shown to be involved in energy metabolism. N2,N2-Dimethylguanosine has been shown to be present at high levels in patients with autoimmune diseases such as rheumatoid arthritis. The x-ray crystal structures of wild-type strains of Escherichia coli and Streptococcus pneumoniae have been determined, which revealed that this compound interacts with the enzyme activity for primary sclerosing cholangitis. This nucleoside can also be detected by LC-MS/MS methods and multivariate logistic regression analysis.</p>
    Formule :C12H17N5O5
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Off-White Powder
    Masse moléculaire :311.3 g/mol

    Ref: 3D-ND05647

    10mg
    230,00€
    25mg
    359,00€
    50mg
    555,00€
    100mg
    970,00€
    250mg
    2.044,00€
  • 2',3'-Dideoxy-5-iodouridine

    CAS :
    <p>2',3'-Dideoxy-5-iodouridine is a synthetic nucleoside analog derived from uridine, one of the natural building blocks of RNA. This molecule has been chemically modified to disrupt the normal processes of DNA and RNA synthesis, making it a candidate for antiviral and anticancer research.</p>
    Formule :C9H11IN2O4
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :338.1 g/mol

    Ref: 3D-ND07998

    2mg
    135,00€
    5mg
    149,00€
    10mg
    239,00€
    25mg
    492,00€
    50mg
    637,00€
  • Guanosine 3',5'-cyclic monophosphate sodium salt

    CAS :
    <p>Guanosine 3',5'-cyclic monophosphate sodium salt (cGMP) is a cyclic nucleotide that is involved in the regulation of many cellular processes. It binds to specific guanine nucleotide-binding proteins (G proteins) and activates protein kinase A, which regulates glucose metabolism and energy production. cGMP also affects neuronal death, axonal growth, and bowel disease by acting as a cyclase inhibitor or activating the immune system. It has been shown to reduce the severity of infectious diseases such as HIV and malaria by activating the immune system.</p>
    Formule :C10H11N5NaO7P
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :367.19 g/mol

    Ref: 3D-NG08975

    1g
    1.120,00€
    2g
    2.078,00€
    100mg
    268,00€
    250mg
    480,00€
    500mg
    705,00€
  • 1-(2'-Deoxy-3',5'-di-O-toluoyl-b-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine

    CAS :
    <p>1-(2'-Deoxy-3',5'-di-O-toluoyl-b-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine is a nucleoside derivative that features a modified pyrimidinone (triazine) base attached to a protected deoxyribose sugar. This molecule can be used in research.</p>
    Formule :C24H24N4O6
    Degré de pureté :Min. 95%
    Couleur et forme :White To Off-White Solid
    Masse moléculaire :464.48 g/mol

    Ref: 3D-ND04704

    10mg
    140,00€
  • 3'-O-Acetyl-5'-O-DMT-5-iodo-2'-O-methyuridine

    CAS :
    <p>3'-O-Acetyl-5'-O-DMT-5-iodo-2'-O-methyuridine is a novel nucleoside analog with antiviral and anticancer activities. It is an activator that binds to the ribonucleotide reductase enzyme, which is essential for the production of RNA and DNA. This compound has been shown to inhibit the growth of several cancer cells in vitro.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA15556

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    À demander
  • 5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine

    CAS :
    <p>5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine is a monophosphate nucleoside that inhibits viral replication by inhibiting the synthesis of both DNA and RNA. This compound is used to treat cancers such as leukemia, lymphoma, and multiple myeloma. It also has antiviral properties that are active against herpes simplex virus (HSV) and human cytomegalovirus (CMV). 5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine is a modified nucleoside with a phosphoramidite group on the 2' position of the ribose sugar.</p>
    Formule :C13H14ClN5O5
    Degré de pureté :Min. 95%
    Couleur et forme :Off-White Powder
    Masse moléculaire :355.74 g/mol

    Ref: 3D-NC06333

    25mg
    135,00€
    50mg
    148,00€
  • Inosine-3',5'-cyclic-monophosphate triethylammonium - 10 mM aqueous solution


    <p>Inosine-3',5'-cyclic-monophosphate triethylammonium is a synthetic nucleoside that functions as an activator of the deoxyribonucleotide synthesis. It has antiviral and anticancer properties, and has been shown to have anti-inflammatory activities. Inosine-3',5'-cyclic-monophosphate triethylammonium has been shown to inhibit the growth of cells in culture and induce apoptosis. This is due to its ability to inhibit DNA synthesis by inhibiting the enzyme ribonucleotide reductase.</p>
    Formule :C10H11N4O7P·NC6H15
    Degré de pureté :Min. 95%
    Masse moléculaire :431.38 g/mol

    Ref: 3D-NI170530

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    À demander
  • 5-Carbamoylmethyluridine

    CAS :
    <p>5-Carbamoylmethyluridine is a nucleoside that is structurally related to uridine. It is synthesized from uridine by methyl esterification with carbamic acid and methoxycarbonyl chloride. 5-Carbamoylmethyluridine interacts with actin filaments and has been shown to alter the expression of messenger RNA in eukaryotes. 5-Carbamoylmethyluridine also acts as a competitive inhibitor of the formation of a ternary complex, which includes ATP, GTP, and UTP, at the level of ribonucleotide reductase. This inhibition leads to decreased synthesis of messenger RNA in cells.</p>
    Formule :C11H15N3O7
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :301.25 g/mol

    Ref: 3D-NC159473

    1mg
    309,00€
    2mg
    463,00€
    5mg
    721,00€
    10mg
    1.011,00€
    25mg
    1.838,00€
  • 5’-O-DMT-2’-b-C-methyladenosine


    <p>5’-O-DMT-2’-b-C-methyladenosine is a modified nucleoside with antiviral and anticancer activity. It is an activator of DNA synthesis, and can be used as a precursor for phosphoramidites for the synthesis of oligonucleotides. The 5’-O-DMT group in this compound may be replaced with other activating groups to synthesize different modified nucleosides.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND163091

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    À demander
  • 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine


    <p>2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine is a nucleoside that is used in the production of DNA and RNA. It is an activator of phosphoramidites, which are used to synthesize oligonucleotides. 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine can be used as an anti-cancer drug and has antiviral activity. It has been shown to inhibit the replication of HIV by interfering with viral enzymes such as reverse transcriptase and integrase. 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine can also be used for the treatment of influenza A virus infections. This drug is highly purified, with a high quality, monophosphate form as well as a diphosphate form. There are no known side effects associated with this product.!--</p>
    Formule :C32H30F3N3O8
    Degré de pureté :Min. 95%
    Masse moléculaire :641.61 g/mol

    Ref: 3D-ND08249

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    À demander
  • Lamivudine 5'-triphosphate triethylammonium salt (Ethanol solution)

    CAS :
    <p>Sold by weight of nucleoside as solution in ethanol.</p>
    Formule :C20H46N5O12P3S
    Degré de pureté :Min. 95%
    Couleur et forme :Clear Liquid
    Masse moléculaire :673.59 g/mol

    Ref: 3D-NL15940

    1mg
    200,00€
    2mg
    315,00€
    5mg
    478,00€
    10mg
    793,00€
    500µg
    134,00€
  • Cytarabine hydrochloride

    CAS :
    <p>Anti-viral; anti-neoplastic</p>
    Formule :C9H13N3O5·HCl
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :279.68 g/mol

    Ref: 3D-NA05780

    10g
    193,00€
    25g
    330,00€
    50g
    510,00€
    100g
    945,00€
    250g
    1.894,00€