Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3567 produits trouvés pour "Nucléosides"
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1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)thymine
CAS :<p>1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)thymine is a chemically modified nucleoside analog. This compound contains a thymine base, a 2'-fluoro-β-D-arabinofuranose sugar, which alters biological stability and function and benzoyl protecting groups at the 3' and 5' positions, commonly used in nucleoside synthesis to control selective modifications.</p>Formule :C23H19FN2O7Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :454.42 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-tritylthymidine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-5'-O-tritylthymidine 3'-CE phosphoramidite is a novel monophosphate derivative that is used as an activator for DNA synthesis. This compound is synthesized by reacting 2,4,6-triisopropylbenzenesilyl chloride with 5'-O-tritylthymidine 3'-hydroxyl in the presence of a base. The resulting intermediate is then converted to the desired product with 1,1'-carbonyldiimidazole and 2-(N,N-dimethylamino)ethoxychloroformate.<br>2'-O-tert-Butyldimethylsilyl-5'-O-tritylthymidine 3'-CE phosphoramidite has been shown to be effective against hepatitis B virus and herpes simplex virus type 1 (HSV1).</p>Formule :C44H59N4O7PSiDegré de pureté :Min. 95%Masse moléculaire :815.04 g/molS-Adenosylmethione-1,4-butanedisulfonate
CAS :<p>S-adenosylmethionine is a compound that is naturally produced in the body and has been shown to be involved in many biochemical reactions. It can be found as a supplement at health food stores, but also is available as a prescription for the treatment of certain liver diseases such as hepatitis. S-adenosylmethionine may have some drug transporter function and can affect the metabolism of other drugs.</p>Formule :C42H74N12O28S8Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :1,451.63 g/mol2-Methoxy-9-(b-D-ribofuranosyl)purine
CAS :<p>2-Methoxy-9-(b-D-ribofuranosyl)purine (2MeO) is a nucleoside that is structurally similar to adenosine. It has antiviral and anticancer activities, as well as the ability to activate phosphoramidites. The 2MeO molecule consists of a modified 9-mer ribofuranose phosphate, which can be synthesized from 2-deoxyribofuranose phosphate by selective oxidation. 2MeO has been shown to inhibit the growth of tumor cells in vitro and in vivo, and also inhibits the replication of DNA and RNA viruses. This drug is considered novel because it does not exist naturally in any organism.</p>Degré de pureté :Min. 95%5-Aminoallyl 2'-deoxycytidine-5'-triphosphate lithium, 100mM aqueous solution
<p>5-Aminoallyl 2'-deoxycytidine-5'-triphosphate lithium salt - 100mM aqueous solution is a novel modified nucleoside that can be activated to the corresponding phosphoramidite.</p>Formule :C12H17N4O13P3•Li4Degré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :545.97 g/mol3’-Deoxy-3’-fluoro-2-thiouridine
CAS :<p>3’-Deoxy-3’-fluoro-2-thiouridine is a nucleoside analog that has been modified to have antiviral and anticancer activity. It is an activator of the ribonucleotide reductase enzyme, which is involved in DNA synthesis. 3’-Deoxy-3’-fluoro-2-thiouridine has been used successfully as an antiviral agent against HIV and other viruses, and as an anticancer agent against leukemia. The monophosphate form of this drug has been shown to inhibit DNA replication in vitro.</p>Degré de pureté :Min. 95%3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine
CAS :Produit contrôlé<p>3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine is a synthetic nucleoside analogue that inhibits the synthesis of DNA. It is a monophosphate and diphosphate analog of thymidine, which are incorporated into DNA during replication. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine is an activator of RNA polymerase II and inhibits viral replication by inhibiting the function of reverse transcriptase. This drug has been shown to be effective against HIV in vitro and in vivo, as well as herpes simplex virus type 1. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine also has antitumor activity as it inhibits the growth of</p>Formule :C16H26N3O5SiD3Degré de pureté :Min. 95%Masse moléculaire :374.52 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite
CAS :<p>2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite is a nucleoside analogue that has been modified to contain an isobutyryl group. It is an activator of the polymerase enzyme, which helps to synthesize DNA. This product can be used in the synthesis of oligonucleotides for use as therapeutic or diagnostic agents.<br>It has anticancer and antiviral activities, due to its ability to inhibit viral replication. This product also has high purity and quality.</p>Formule :C44H54N7O8PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :839.92 g/molN2-DMF-guanosine
<p>N2-DMF-guanosine is a novel antiviral agent that has been synthesized by modifying the nucleoside guanosine. It is an analog of guanosine in which the 2'-hydroxyl group has been replaced with a 2'-deoxy-2'-fluoro group, and it inhibits viral replication by inhibiting viral DNA polymerase. N2-DMF-guanosine is also used as a high quality deoxyribonucleoside monophosphate for the synthesis of ribonucleosides and nucleosides. This compound has a CAS number of 6074-37-4.</p>Formule :C13H18N6O5Degré de pureté :Min. 95%Masse moléculaire :338.32 g/mol5'-O-p-Anisoyl-N6-benzoyl-2'-deoxyadenosine
<p>5'-O-p-Anisoyl-N6-benzoyl-2'-deoxyadenosine is a novel nucleoside analog with anticancer, antiviral, and antimalarial activities. It is synthesized by the condensation of 2'-deoxyadenosine with anisic acid in the presence of phosphoramidites. The compound is a potent inhibitor of DNA synthesis in cultured cells, and has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) in vitro. 5'-O-p-Anisoyl-N6-benzoyl-2'-deoxyadenosine also exhibits antiinflammatory activity against carrageenan induced paw edema in rats.</p>Formule :C25H23N5O6Degré de pureté :Min. 95%Masse moléculaire :489.48 g/mol5-Hydroxymethylcytidine
CAS :<p>5-Hydroxymethylcytidine is a nucleoside that has been shown to inhibit the activity of RNA polymerase by forming hydrogen bonds with the enzyme. It is used in vitro to study the role of messenger RNA in regulating gene expression, and also as a probe for transcriptase activity. 5-Hydroxymethylcytidine has also been shown to have a biological function in solid tumours and may be an analytical method for detecting cancer.</p>Formule :C10H15N3O6Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :273.24 g/mol5'-O-DMT-N2-phenoxyacetyl-2'-O-methylguanosine 3'-CE phosphoramidite
<p>5'-O-DMT-N2-phenoxyacetyl-2'-O-methylguanosine 3'-CE phosphoramidite is a nucleoside analog that inhibits DNA synthesis by forming a covalent bond with the beta-subunit of DNA polymerase. It is a modified nucleoside that has been synthesized from 2'-O-methylguanosine and N2,N2-dimethoxyacetyl. 5'-O-DMT-N2-phenoxyacetyl-2'-O methylguanosine 3'-CE phosphoramidite possesses the CAS No. 16053526.</p>Degré de pureté :Min. 95%3’-Deoxy-3’-α-C-methyl-N6,N6-dimethyladenosine
<p>3’-Deoxy-3’-alpha-C-methyl-N6,N6-dimethyladenosine is a nucleoside with anticancer activity. It is a novel nucleoside that has been shown to have antiviral and antitumor activities. Research has shown that 3’-Deoxy-3’-alpha-C-methyl-N6,N6-dimethyladenosine inhibits tumor growth in animals without toxicity to the normal cells of the body. This nucleoside also has an effect on DNA and RNA synthesis, which may be due to its ability to inhibit viral replication enzymes.</p>Degré de pureté :Min. 95%3’,2-anhydro-2'-deoxyuridine
CAS :<p>3’,2-anhydro-2'-deoxyuridine is a nucleoside analog that has antiviral and anticancer activities. It is an activator of the ribonucleotide reductase enzyme, which catalyses the conversion of ribonucleotide diphosphates to deoxynucleotides. 3’,2-anhydro-2'-deoxyuridine also inhibits DNA synthesis by cytostatic mechanisms. This product is used as a building block in phosphoramidite synthesis and can be used for the preparation of novel nucleosides and phosphoramidites. This product was originally synthesized for use as an antiviral agent against herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV). It is also used as an anticancer agent in preclinical research.</p>Degré de pureté :Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-MMT-uridine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-5'-O-MMT-uridine 3'-CE phosphoramidite is a monophosphate that is synthesized by reacting 2'-O-tert-butyldimethylsilyl-5'-O-methylguanosine 3'-CE with uridine 3'-CE. This nucleoside has been shown to be an activator of the immune system and to inhibit cancer cell growth in vitro. It also inhibits the synthesis of DNA and RNA, as well as ribonucleosides and deoxyribonucleosides. The purity of this product is high, with no detectable impurities or toxic substances known to the manufacturer. It is also stable at room temperature for at least six months. This product does not contain any phosphate groups or other reactive functional groups that could interfere with downstream reactions.<br>2'-O-tert-Butyldimethylsily</p>Formule :C44H59N4O8PSiDegré de pureté :Min. 95%Masse moléculaire :831.04 g/mol3'-Azido-3'-deoxy-5'-O-DMT-D3-thymidine
Produit contrôlé<p>3'-Azido-3'-deoxy-5'-O-DMT-D3-thymidine is a novel nucleoside that has antiviral, anticancer and phosphoramidite activities. It is an activator of the thymidine kinase enzyme and phosphorylates its substrate to form 3'-azido-3'-deoxy-5'-O-DMT-diphosphate. It is also a monophosphate and diphosphate analog of thymidine. This product can be used in the synthesis of DNA or RNA by modifying the sugar moiety. 3'-Azido-3'-deoxy-5'-O-DMT-D3 -thymidine can also be used for anticancer therapy because it inhibits ribonucleotide reductase, which is necessary for DNA synthesis.</p>Formule :C31H28N5O7D3Degré de pureté :Min. 95%Masse moléculaire :588.62 g/mol5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine
CAS :<p>5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine is a synthetic nucleoside that belongs to the class of deoxyribonucleosides. It is a modified nucleoside with an anisoyl group at the 5' position and a benzoyl group at the 2' position. This product can be used in the synthesis of DNA, RNA, and phosphoramidites. 5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine has antiviral properties and has been shown to inhibit viral replication in vitro and in vivo. It also has anticancer activities as it inhibits cell proliferation and induces apoptosis, which may be due to its ability to inhibit DNA synthesis.</p>Formule :C24H23N3O6Degré de pureté :Min. 95%Masse moléculaire :449.46 g/molN4-Acetyl-2'-deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-cytidine
CAS :<p>N4-Acetyl-2'-deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-cytidine is a novel anticancer agent that is modified with a phosphoramidite. It is a nucleoside analog that selectively inhibits DNA polymerases and RNA polymerases, and therefore prevents the synthesis of DNA and RNA. N4-Acetyl-2'-deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-cytidine has been shown to be highly active against various cell lines in vitro, including human leukemia cells (HL60), human prostate cancer cells (PC3), human breast cancer cells (MCF7), and human mammary tumor cells (HTB6). This compound has also been shown to have antiestrogenic activity in vivo.</p>Formule :C32H33N3O7Degré de pureté :Min. 98 Area-%Masse moléculaire :571.62 g/mol5'-Adenylic acid monoanhydride with (dichlorophosphonomethyl)phosphonic acid
CAS :<p>5'-Adenylic acid monoanhydride with (dichlorophosphonomethyl)phosphonic acid is a neuronal blocker that inhibits the enzyme acetylcholinesterase. It is an efficient inhibitor of AChE and has been shown to be effective in animal models of Alzheimer's disease. The inhibition of AChE by 5'-Adenylic acid monoanhydride with (dichlorophosphonomethyl)phosphonic acid leads to increased levels of acetylcholine, which can stimulate nerve impulses and slow or stop the progression of Alzheimer's disease.</p>Formule :C11H16Cl2N5O12P3Degré de pureté :Min. 95%Masse moléculaire :574.1 g/mol9-(b-D-Arabinofuranosyl)isoguanine
CAS :<p>9-(b-D-Arabinofuranosyl)isoguanine is a modified nucleoside that has antiviral activity. It is synthesized by substituting the 2'-hydroxyl group of deoxyribose with an arabinofuranose, which can be phosphorylated to form 9-(b-D-arabinofuranosyl)isoguanine 5'-monophosphate. This novel antiviral agent inhibits the synthesis of viral DNA and RNA, and is effective against a wide range of viruses in vitro. The drug was shown to have anticancer activities in animal models and has been patented for use as a chemotherapeutic agent against leukemia, lymphoma, and other cancers.</p>Formule :C10H13N5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :283.25 g/mol
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