Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3567 produits trouvés pour "Nucléosides"
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β-Nicotinamide adenine dinucleotide sodium dihydrate
CAS :<p>Coenzyme and regenerating electron donor in catabolic processes</p>Formule :C21H26N7NaO14P2•(H2O)2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :721.44 g/mol2',3',5'-Tri-O-acetyl-6-azauridine
CAS :<p>2',3',5'-Tri-O-acetyl-6-azauridine is a nucleoside analog for research purposes. The replacement of a carbon atom with a nitrogen atom on the uracil base affects how the molecule interacts with cellular processes. It has the potential to interfere with normal metabolic processes within cells, particularly those related to RNA synthesis. Due to its ability to disrupt cell growth, it could be studied for any potential antiviral or antitumor properties.</p>Formule :C14H17N3O9Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :371.3 g/mol5-Chloro-2-iodopyrimidine
CAS :<p>5-Chloro-2-iodopyrimidine is an organic molecule that belongs to the class of trifluoromethylated molecules. It was discovered by a team of chemists in 2006 and has been used as a reagent for the efficient trifluoromethylation of organic molecules. 5-Chloro-2-iodopyrimidine can be catalyzed with copper, which is responsible for its unique reactivity. The synthesis of this molecule has been shown to be efficient in organic chemistry.<br>END></p>Formule :C4H2ClIN2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :240.43 g/molb-Nicotinamide mononucleotide
CAS :<p>b-Nicotinamide mononucleotide, or NMN, is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme found in all living cells that is essential for various metabolic processes. NAD+ is involved in critical functions such as DNA repair, gene expression, and cellular stress responses.</p>Formule :C11H15N2O8PDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :334.22 g/mol3-Methyl-2-nitropyridine
CAS :<p>3-Methyl-2-nitropyridine is a high yield byproduct of formamide, which can be activated to form an intermediate for the synthesis of nucleosides. The kinetics and labeling of this intermediate were studied using a transfer experiment. 3-Methyl-2-nitropyridine is acidic, with a pKa value of 3.6, and is reactive towards nucleophiles. It is also catalytic, yielding methyl groups and dioxane as products when heated at temperatures between 180°C and 220°C. In addition, it undergoes nucleophilic substitutions at methoxy groups.</p>Formule :C6H6N2O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :138.12 g/molN4-Benzoyl-2'-deoxycytidine
CAS :<p>N4-Benzoyl-2'-deoxycytidine is a fluorescent nucleoside that has been used to study the molecular interactions between sugar residues and the phosphate groups of nucleic acids. It is used as a reagent for glycosidation, which involves the formation of a glycosidic linkage between an alcohol group in a saccharide or oligosaccharide and the hydroxyl group in an aromatic acid. N4-Benzoyl-2'-deoxycytidine has also been synthesized by solid-phase techniques. This synthetic method is based on phosphoramidite chemistry and uses an automated DNA synthesizer to produce oligonucleotides with specific sequences. The synthesis of this nucleoside relies on the use of fluorescent dyes such as fluorescein, rhodamine, and coumarin to monitor progress during synthesis.</p>Formule :C16H17N3O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :331.33 g/molInosine 5'-triphosphate lithium salt
<p>Inosine 5'-triphosphate lithium salt is a nucleoside that is used as an activator for DNA polymerase in the synthesis of deoxyribonucleotides. It has been shown to have anticancer properties and can be used to treat leukemia, lymphoma, and ovarian cancer. Inosine 5'-triphosphate lithium salt has also been shown to inhibit the growth of bacteria by inhibiting RNA synthesis.</p>Formule :C10H15N4O14P3FDegré de pureté :Min. 95%Masse moléculaire :527.16 g/molN2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine
CAS :<p>N2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-diyl)guanosine is a nucleoside that is activated by phosphorylation. It has been shown to be an inhibitor of cancer cell growth and proliferation in vitro. This compound was also found to inhibit the expression of two oncogenes (c-MYC and c-Ki67) and induce the expression of the tumor suppressor gene p53. This nucleoside is synthesized from 2'-deoxyadenosine monophosphate (2'-DAMP) with a modified DNA synthesis protocol.</p>Formule :C26H45N5O7Si2Degré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :595.84 g/mol3'-Deoxy-3'-iodothymidine
CAS :<p>3'-Deoxy-3'-iodothymidine is a nucleoside that is found in DNA. It has a constant of -1.5 and can be protonated to form the anion. The molecule has a reactive radical anion, which is stabilized by electron delocalization with the aromatic rings. 3'-Deoxy-3'-iodothymidine has been studied for use as a medicine for cancer treatment, but it also has applications in biology and chemistry. This compound can be used in conductometry and electron spectroscopy, as well as other chemical experiments that require ionic compounds or radiation.</p>Formule :C10H13IN2O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :352.13 g/mol2’-Amino-2’-deoxy-β-D-arabinouridine
CAS :<p>2’-Amino-2’-deoxy-β-D-arabinouridine is a modified nucleoside based on uridine, in which the 2'-hydroxyl group of the sugar has been replaced with an amino group, and the sugar itself is arabinose (a stereoisomer of ribose). This compound is of possible interest in nucleic acid chemistry and antisense or RNA-interference research.</p>Formule :C9H13N3O5Degré de pureté :Min. 95%Couleur et forme :solid.Masse moléculaire :243.22 g/mol9-(2'-Deoxy- 2'- fluoro- a- D- arabinofuranosyl) -9H- purin- 6- amine
CAS :<p>9-(2'-Deoxy- 2'- fluoro- a- D- arabinofuranosyl) -9H- purin- 6- amine is an antiviral and anticancer agent. It can be used as a monophosphate or as a phosphoramidite for the synthesis of DNA, RNA, and modified nucleosides. The chemical name is 9-(2'-deoxy-2'-fluoro-a-D-arabinofuranosyl)-9H-purin-6-amine. It has the CAS number 20187-82-0. This drug was synthesized in 1976 by Koehler and colleagues at Bayer.<br>The molecular weight is 268.46 g/mol, with a melting point of 190°C, boiling point of 320°C and density of 1.408 g/mL at 20°C. It is soluble in water, methanol, ethanol, chloroform and acetic acid</p>Formule :C10H12FN5O3Degré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :269.23 g/mol4-Amino-5-chloro-2,6-dimethylpyrimidine
CAS :<p>4-Amino-5-chloro-2,6-dimethylpyrimidine is a supramolecular complex that is characterized by the coordination geometry of its metal ion and the donor atoms. It has been proposed as a potential drug for the treatment of bacterial infections, such as tuberculosis. The 4-Amino-5-chloro-2,6,dimethylpyrimidine is structurally similar to nucleobases and may be able to form hydrogen bonds with water molecules. This molecule also has a high melting point and is not soluble in water. It can be protonated at different pH values and forms complexes with hydroxyl groups found in nucleic acids.</p>Formule :C6H8ClN3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :157.6 g/mol(2R,3R,4S,5R)-2-(4-Aminothieno[3,4-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CAS :<p>(2R,3R,4S,5R)-2-(4-Aminothieno[3,4-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol is a nucleoside analog for research purposes</p>Formule :C11H13N3O4SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :283.3 g/mol2'-O-Propargylcytidine
CAS :<p>2'-O-Propargylcytidine is a novel nucleoside that has been modified from cytidine. It is designed to inhibit the activity of RNA polymerase and to be used in anticancer therapy. The synthesis of 2'-O-propargylcytidine has been achieved by modifying the nucleotide with propargylic chloride, which is then reacted with sodium cyanide. The resulting product is purified by column chromatography and recrystallization.<br>2'-O-Propargylcytidine is a phosphoramidite that can be used for DNA synthesis or as a monophosphate in RNA synthesis. This high purity product has a CAS number of 206552-85-4 and it can be used as an activator for ribonucleosides, such as adenosine, guanosine, uridine, cytidine, and thymidine.</p>Formule :C12H15N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :281.26 g/mol2'-Deoxyisocytidine
CAS :<p>2'-deoxyisocytidine is a nucleoside that is used in biochemical research. It can be synthesized by two methods: solid-phase synthesis and depyrimidination. 2'-deoxyisocytidine has been shown to be more efficient than other fluorescent nucleosides when used with the excimer laser technique. The stability of this compound has also been shown to be greater than other fluorescein-based compounds, which makes it an appropriate substitute when using phosphoramidite chemistry.</p>Formule :C9H13N3O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :227.22 g/molQueuine hydrochloride
CAS :<p>Queuine is a modified nucleoside found in tRNA. It is synthesized from guanosine by the enzyme queuine tRNA-ribosyltransferase, which converts guanosine to queuosine. Queuine hydrochloride is a synthetic form of queuine that can be used for research purposes to examine the anticodon loop and other structural features of the molecule. The prokaryotic and eukaryotic organisms studied showed different levels of synthesis of queuine, with bacteria synthesizing more than mammals. Bacteria were found to have a greater affinity for queuine than eukaryotes, which may be due to modification of the trna anticodon loop or to differences in ribosomal proteins.</p>Formule :C12H15N5O3·HClDegré de pureté :(%) Min. 90%Couleur et forme :Light (Or Pale) Beige To Light (Or Pale) Purple SolidMasse moléculaire :313.74 g/molN2-Isobutyryl-2'-O-methylguanosine
CAS :<p>N2-Isobutyryl-2'-O-methylguanosine (IBOG) is a modified nucleoside that can be used as an activator for DNA synthesis. IBOG is a high purity, high quality chemical with CAS No. 63264-29-9 and has antiviral and anticancer properties.</p>Formule :C15H21N5O6Degré de pureté :Min. 95%Couleur et forme :White To Yellow SolidMasse moléculaire :367.36 g/mol2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite is a novel modified ribonucleoside that has been synthesized to mimic the natural nucleotide. It has been shown to activate DNA synthesis, inhibit cancer cell division and proliferation, and inhibit viral replication. 2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMTguanosine 3'-CE phosphoramidite is a monophosphate nucleotide with an anticancer activity. It has also showed antiviral effects against HIV and Hepatitis B virus. This novel modified ribonucleoside is highly pure and can be used for the synthesis of high quality DNA, RNA, or phosphoramidites.</p>Formule :C49H66N7O8PSiDegré de pureté :Min. 95%Masse moléculaire :940.17 g/molN6-Cyclopentyl-2'-C-methyl-adenosine
CAS :<p>N6-Cyclopentyl-2'-C-methyl-adenosine is an antiviral agent that inhibits the synthesis of DNA by preventing the formation of RNA from DNA. It has been shown to be effective against HIV and other retroviruses. N6-Cyclopentyl-2'-C-methyl-adenosine is a synthetic nucleoside that is activated by phosphorylation in cells, which leads to the synthesis of monophosphate (5'-AMP). This compound is used for the treatment of cancer and HIV infection.</p>Formule :C16H23N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :349.39 g/mol
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