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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3567 produits trouvés pour "Nucléosides"

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  • 3',5'-Di-O-acetyl-5-bromo-2'-deoxyuridine

    CAS :
    <p>Please enquire for more information about 3',5'-Di-O-acetyl-5-bromo-2'-deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formule :C13H15BrN2O7
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :391.18 g/mol

    Ref: 3D-ND04658

    1g
    148,00€
  • 3’-O-tert-butyldimethylsilyl-5’-O-DMT-N1-methylpseudouridine

    CAS :
    <p>3′-O-tert-butyldimethylsilyl-5′-O-DMT-N1-methylpseudouridine is a synthetic nucleoside that is used in the synthesis of deoxyribonucleosides. It is an activator nucleoside that has antiviral activity and provides high purity, novel monophosphate nucleosides, and modified nucleosides. 3′-O-tert-butyldimethylsilyl-5′-O-DMT-N1 methylpseudouridine has CAS No. 875302–43–5 and can be used for the synthesis of phosphoramidites or ribonucleotides.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB162907

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  • Flavin adenine dinucleotide

    CAS :
    <p>Flavin adenine dinucleotide, also known as FAD, plays a crucial role in several enzymatic reactions involved in metabolism. It is essential for the function of flavoproteins, which are involved in processes such as the electron transport chain and the citric acid cycle.</p>
    Formule :C27H33N9O15P2
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :785.5 g/mol

    Ref: 3D-NF182245

    25mg
    264,00€
    50mg
    413,00€
    100mg
    588,00€
    250mg
    1.044,00€
  • N4-Benzoyl-5'-O-benzoyl-2'-deoxycytidine

    CAS :
    <p>N4-Benzoyl-5'-O-benzoyl-2'-deoxycytidine is a nucleoside monophosphate that is used in the treatment of HIV infection. The antiviral activity of N4-Benzoyl-5'-O-benzoyl-2'-deoxycytidine is due to its ability to inhibit viral DNA synthesis by competing with natural substrates for incorporation into the growing chain. This compound also inhibits cancer cell proliferation and may be useful in the treatment of other forms of cancer. N4-Benzoyl-5'-O-benzoyl-2'-deoxycytidine is synthesized from 2,4,6,-trichlorophenylpiperazine (TCPP) and cyanogen bromide in a two step process using phosphoramidites.</p>
    Formule :C23H21N3O6
    Degré de pureté :Min. 95%
    Masse moléculaire :435.44 g/mol

    Ref: 3D-NB08667

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  • N4-Benzoyl-2’,3’-di-O-tert-butyldimethylsilyl-5’-O-DMT-N4-methylcytidine


    <p>N4-Benzoyl-2’,3’-di-O-tert-butyldimethylsilyl-5’-O-DMT-N4-methylcytidine is a modified nucleoside that is used as an antiviral agent. It inhibits the activity of reverse transcriptase, which is an enzyme that catalyzes the conversion of RNA into DNA. This nucleoside inhibits viral replication and prevents the production of new viruses in cells infected by HIV. N4-Benzoyl-2’,3’-di-O -tert -butyldimethylsilyl -5’ -O -DMT -N4 methylcytidine also inhibits DNA synthesis by inhibiting the activity of DNA polymerases.<br>This drug has been shown to be effective against cancer cells and may have anticancer properties.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB162891

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  • 2-Acetamido-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine

    CAS :
    <p>2-Acetamido-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a modified purine nucleoside, protected with acetyl groups, which protect the sugar during chemical reactions. This compound is based on a purine ring and also contains an acetamido group at position 2, a chlorine atom at position 6 and a β-D-ribofuranosyl sugar.</p>
    Formule :C18H20ClN5O8
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :469.83 g/mol

    Ref: 3D-NA04442

    1g
    1.334,00€
    2g
    2.369,00€
    100mg
    239,00€
    250mg
    454,00€
    500mg
    781,00€
  • 6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine


    <p>6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine (6ADRP) is a synthetic nucleoside that is used as an activator of ribonucleosides and diphosphates in DNA synthesis. 6ADRP has antiviral activity against HIV and herpes simplex virus type 1. It binds to the viral DNA polymerase and prevents the addition of nucleotides to the growing DNA strand. 6ADRP is phosphorylated by T7 kinase to form the active metabolite, 6-amino-1-(2'-deoxy-[alpha]-D-ribofuranosyl)-5'-triphosphate (6ATP), which inhibits viral replication by preventing the formation of RNA primers.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA162940

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  • 2-Iodoadenosine

    CAS :
    <p>2-Iodoadenosine is a chemical compound that is produced from the oxidation of uridine. It is used in the synthesis of peptides, which are important for biological processes like signal transduction and cell growth. 2-Iodoadenosine can be made by coupling other molecules to an adenosine molecule. This process involves a cross-coupling reaction with palladium catalysts or hydroxylation reactions with sodium borohydride. The resulting product has been shown to have anticancer and anti-microbial activities against protozoan parasites and cyclic peptide structures.</p>
    Formule :C10H12IN5O4
    Degré de pureté :Min. 97 Area-%
    Couleur et forme :Powder
    Masse moléculaire :393.14 g/mol

    Ref: 3D-NI04749

    1g
    430,00€
    2g
    598,00€
    5g
    962,00€
    10g
    1.494,00€
    500mg
    250,00€
  • Adenosine 5'-difluoromethylene-5'-triphosphate triethylammonium salt


    <p>Adenosine 5'-difluoromethylene-5'-triphosphate triethylammonium salt is a novel nucleotide activator that has antiviral, anticancer, and ribonucleoside activities. This activator is a phosphoramidite monomer with an adenine base. The pharmaceutical industry uses this activator as a starting material in the synthesis of anticancer drugs and antiviral drugs. It is also used as a reagent in the production of modified DNA and RNA molecules for use in gene therapy and drug discovery.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA31345

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  • N6-Benzoyl-8-hydroxy-2'-O-methyladenosine


    <p>N6-Benzoyl-8-hydroxy-2'-O-methyladenosine is a nucleoside analogue that inhibits the replication of RNA and DNA. It is a monophosphate, which can be converted to a diphosphate through phosphorylation. N6-Benzoyl-8-hydroxy-2'-O-methyladenosine has been shown to inhibit cancer cells and may have potential for use in antiviral therapy. This compound was synthesized from 2,4,5,6 tetrahydrobenzyl alcohol and 2'-deoxyadenosine. The CAS number for this compound is 79430-89-1.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB145742

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  • 7-(2-C-Methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

    CAS :
    <p>7-(2-C-Methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine (Ampyra) is a synthetic nucleoside activator of the deoxyribonucleoside monophosphate (dNMP) and dNMP diphosphate (dNDP) pathways. It has antiviral and anticancer activities, as well as an inhibitory effect on DNA synthesis by blocking the polymerization of deoxyribonucleotides.<br>It is also an inhibitor of histone acetyltransferase and may be useful in the treatment of Alzheimer's disease. Ampryra is a novel compound with high purity and high quality. It is phosphoramidite that can be used for the preparation of oligodeoxynucleotides for use in DNA sequencing or gene therapy.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NM14094

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  • 2-Chloro-6-O-methylinosine

    CAS :
    <p>2-Chloro-6-O-methylinosine is a modified nucleoside analog. Its structure is based on inosine and at position 2 a chlorine atom replaces the hydrogen. At position 6, the keto oxygen (normally part of the purine ring) is O-methylated, forming a methoxy group (-OCH₃)</p>
    Formule :C11H13ClN4O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :316.7 g/mol

    Ref: 3D-NC16520

    100mg
    167,00€
  • 8-Bromoinosine

    CAS :
    <p>8-Bromoinosine is a potent chemical probe that can be used to study the molecular mechanism of cGMP-dependent protein kinase (PKG). 8-Bromoinosine reacts with the acceptor site in PKG, which is located at the base of the active site cleft. Electrons from hydrogen bond donor sites on 8-bromoadenosine are transferred to chloride ion and the resulting 8-bromoinosine chloride complex is an effective inhibitor of PKG. It has been shown that stereoselectivity plays a role in this reaction mechanism.</p>
    Formule :C10H11BrN4O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :347.13 g/mol

    Ref: 3D-NB08274

    50mg
    256,00€
    100mg
    376,00€
    250mg
    669,00€
    500mg
    951,00€
  • 2,3'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine


    <p>2,3'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine is a synthetically modified thymidine analog for use in research</p>
    Degré de pureté :Min. 95%
    Couleur et forme :White to off-white solid.

    Ref: 3D-NA145608

    1g
    134,00€
    2g
    200,00€
    5g
    403,00€
    10g
    598,00€
  • 2'-Deoxy-2'-fluoroadenosine

    CAS :
    <p>2’-Deoxy-2’-fluoro nucleosides and nucleotides have been shown to demonstrate anti-viral activity against influenza, SARS and HIV. More specifically the phosphonate of 2'-Deoxy-2'-fluoroadenosine has been evaluated as an inhibitor of Hepacivirus C (HCV).</p>
    Formule :C10H12FN5O3
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :269.24 g/mol

    Ref: 3D-ND02827

    5g
    358,00€
    10g
    502,00€
    25g
    786,00€
    50g
    1.139,00€
    100g
    1.765,00€
  • N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite

    CAS :
    <p>N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite is a modified nucleoside, which is an important building block for DNA and RNA synthesis. It is synthesized by the condensation of 6-benzoyladenosine with 2'-O-propynyladenosin. The stability of this compound has been demonstrated by its resistance to hydrolysis and oxidation, while it can also be activated with a variety of activators, including NaBH4 or NaCNBH3. This novel nucleotide has shown anticancer activity in vivo and antiviral activity against HIV.</p>
    Formule :C50H54N7O8P
    Degré de pureté :Min. 95%
    Masse moléculaire :911.98 g/mol

    Ref: 3D-PB139174

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  • 6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine

    CAS :
    <p>6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine is a novel nucleoside that has been shown to be an efficient activator of the transcription factor NFκB in vitro. 6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine is synthesized by phosphoramidite chemistry and purified by HPLC. It has been demonstrated to inhibit the replication of human immunodeficiency virus (HIV) in a dose dependent manner, which may be due to its ability to inhibit the synthesis of viral DNA and RNA. This product is highly pure and can be used for many purposes, including as a synthetic building block for DNA or as an antiviral drug.</p>
    Formule :C11H12ClN3O4
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :285.69 g/mol

    Ref: 3D-NC05369

    1g
    1.910,00€
    2g
    2.951,00€
    100mg
    268,00€
    250mg
    500,00€
    500mg
    717,00€
  • 1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N4-benzoylcytidin-1-yl)-D-altro-hexitol

    CAS :
    <p>1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N4-benzoylcytidin-1-yl)-D-altro-hexitol is a synthetic nucleoside analog for use in research</p>
    Formule :C24H22N2O7
    Degré de pureté :Min. 95%
    Couleur et forme :White To Off-White Solid
    Masse moléculaire :450.45 g/mol

    Ref: 3D-NA07163

    1g
    550,00€
    50mg
    135,00€
    100mg
    154,00€
    200mg
    235,00€
    500mg
    457,00€
  • 1-(2’-Deoxy-2’-fluoro-b-D-arabinofuranosyl)-N3-[3-(tert-butoxycarbonyl)amino]propyluracil

    CAS :
    <p>1-(2’-Deoxy-2’-fluoro-b-D-arabinofuranosyl)-N3-[3-(tert-butoxycarbonyl)amino]propyluracil is a nucleoside with antiviral and anticancer properties. It is an activator of DNA synthesis and has been shown to inhibit the proliferation of cancer cells. 1-(2’-Deoxy-2’-fluoro-b-D-arabinofuranosyl)-N3-[3-(tert-butoxycarbonyl)amino]propyluracil is a modified nucleoside that has been synthesized by modifying the sugar moiety of ribonucleosides or deoxyribonucleosides. It contains a 2'-deoxypyrimidine base, which can be substituted with different atoms or groups to produce different drugs. The drug inhibits viral replication by inhibiting the growth of</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND162853

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  • 2'-Deoxy-6-thioguanosine-5'-monophosphate

    CAS :
    <p>Azathioprine is a drug that suppresses the immune system and is used to treat autoimmune disorders such as rheumatoid arthritis, lupus erythematosus, and inflammatory bowel disease. It is an immunosuppressant that prevents the formation of antibodies by blocking the enzyme thiopurine S-methyltransferase. Azathioprine is metabolized in the liver to 6-mercaptopurine, which has been shown to cause leukopenia. The genetic polymorphism of this enzyme can lead to differences in the metabolism and toxicity of azathioprine therapy.</p>
    Formule :C10H14N5O6PS
    Degré de pureté :Min. 95%
    Masse moléculaire :363.29 g/mol

    Ref: 3D-ND159697

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    À demander