Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3573 produits trouvés pour "Nucléosides"
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2,2'-Anhydro-L-uridine
CAS :2,2'-Anhydro-L-uridine is a nucleoside used in for research purposes. It is of particular interest due to it being an L-isomer which is different from the D-form sugars used by the human body. It is useful to study these kinds of molecules for their use in medicine, especially as antiviralsFormule :C9H10N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :226.19 g/molN4-Acetyl-2'-deoxycytidine
CAS :N4-Acetyl-2'-deoxycytidine is a nucleoside analogue that acts as an inhibitor of DNA synthesis. It binds to the active site of the enzyme ribonucleotide reductase, blocking the conversion of ribonucleotides to deoxyribonucleotides. This prevents DNA synthesis and replication, which leads to cell death. N4-Acetyl-2'-deoxycytidine has been shown to be more efficient than other analogues in terms of energy efficiency, control levels, and constant linear model. This compound is reactive and can cause low yields when isolated from solutions with high concentrations. A diode can be used for analytical purposes, while calcium binding may be used as a mathematical model in order to analyze this drug.Formule :C11H15N3O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :269.25 g/molN4-Benzoyl-2'-O-propargyladenosine
CAS :N4-Benzoyl-2'-O-propargyladenosine (BAP) is an antiviral monophosphate nucleoside that inhibits the synthesis of DNA. It is a novel, synthetic, and high quality nucleoside with antiviral activity. BAP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1), human cytomegalovirus (HCMV), and herpes simplex virus type 2 (HSV2). This drug also has anticancer activity as it inhibits the production of cancer cells in vitro. As a phosphoramidite, BAP can be used for the synthesis of DNA.Degré de pureté :Min. 95%N6-Benzoyl-5'-O-benzyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite
N6-Benzoyl-5'-O-benzyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite is an activator of ribonucleosides and deoxyribonucleosides. It is a novel synthetic nucleoside, which has high quality and purity. The chemical modification of the base allows for the synthesis of DNA with modified bases. This product has been shown to have anticancer effects in vitro and in vivo, as well as antiviral activities against HIV.Formule :C39H54N7O6PSiDegré de pureté :Min. 95%Masse moléculaire :775.97 g/molO2-3'-anhydro-β-D-fructofuranosyluracil
O2-3'-anhydro-beta-D-fructofuranosyluracil is a novel nucleoside analogue that has antiviral and anticancer properties. It is synthesized by the reaction of beta-D-fructofuranosyluracil with phosphoramidites. The product is purified by HPLC and characterized by IR spectroscopy, UV spectroscopy, and mass spectrometry.Degré de pureté :Min. 95%9-(b-D-Arabinofuranosyl)adenine
CAS :9-(b-D-Arabinofuranosyl)adenine is a nucleoside that is used as an antiviral agent. It binds to viral RNA and inhibits viral replication. 9-(b-D-Arabinofuranosyl)adenine has been shown to have potent side-effect profiles, including myocardial infarct, neuronal death, and immunological reactions. These effects are due to its ability to inhibit the synthesis of guanine nucleotides in the heart and brain cells, which are essential for energy production and neurotransmitter release respectively. 9-(b-D-Arabinofuranosyl)adenine also binds to toll-like receptors (TLRs), which are proteins found on the surface of cells that recognize invading microbes or foreign substances. This binding leads to activation of immune response pathways.Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :267.24 g/mol6-Azauridine-5'-monophosphate
CAS :6-Azauridine-5'-monophosphate (6-AU) is a compound that is synthesized by the enzyme Azoarcus sp. 6-AU synthetase and is a precursor to azauridine, an intermediate in the biosynthesis of purines. It has been shown to inhibit bacterial growth in tissue culture and depression in mice. The kinetic data were obtained using a titration calorimetry assay at 25 degrees Celsius using subtilis. This drug also has convulsant effects on animals and can cause orotic aciduria when administered orally in high doses. 6-AU has been shown to be effective against cancer cells as well as infectious diseases such as tuberculosis and malaria.
Formule :C8H12N3O9PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :325.17 g/molStavudine 5'-triphosphate sodium salt - 100 mM aqueous solution
Stavudine 5'-triphosphate sodium salt is a modified nucleoside analog with antiviral and anticancer properties. It is a phosphoramidate of stavudine, which has been modified by the replacement of the L-cysteine moiety with a 2-thiophenecarboxamide group. The novel chemical structure of stavudine 5'-triphosphate sodium salt leads to higher solubility in water than other analogues and improved pharmacokinetics. Stavudine 5'-triphosphate sodium salt is an activator for the synthesis of DNA, RNA, and protein. It also inhibits viral replication by interfering with viral DNA polymerase and ribonucleotide reductase, which are essential enzymes for viral replication.Formule :C10H17N2O13P3·xNaDegré de pureté :Min. 95 Area-%Couleur et forme :Clear LiquidMasse moléculaire :466.17 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-thiophosphoramidite
N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-thiophosphoramidite is a novel nucleoside that has been shown to inhibit the growth of cancer cells in vitro. It is an analogue of cytidine and inhibits DNA synthesis by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. This drug also inhibits the synthesis of viral RNA in cells infected with human immunodeficiency virus (HIV) and herpes simplex virus type 1 (HSV-1). N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-thiophosphoramidite is a phosphoramidite that is synthesized from 2,4,6-trichlorobenzoyl chloride, 5'-O-[(N,N-diisopropFormule :C50H51N4O8PS2Degré de pureté :Min. 95%Masse moléculaire :931.07 g/molN2-Acetyl-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite
CAS :N2-Acetyl-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is an organic compound that has been modified to be an anticancer agent. It has been shown to have antiviral and antiparasitic activities. N2-Acetyl-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is a nucleoside analog, which means it substitutes for the natural ribonucleoside in DNA or RNA. The modified nucleotide prevents the incorporation of the normal nucleotide into DNA or RNA, thereby inhibiting replication. This compound also inhibits tumor growth by interfering with viral replication and inhibiting tumor angiogenesis.Formule :C43H52N7O9PDegré de pureté :Min. 95%Masse moléculaire :841.89 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine
CAS :N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine is a versatile nucleoside building block.
Formule :C38H35N5O6Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :657.72 g/molXanthosine 5'-monophosphate disodium salt
CAS :Xanthosine 5'-monophosphate disodium salt is a nucleotide that has been shown to react with nitrite in aqueous solution to form xanthosine 5'-monophosphate. The reaction system can be prepared by adding nitrite to a solution of xanthosine 5'-monophosphate disodium salt and deionized water. The crystallization process can be done by adding ethanol dropwise to the reaction system under controlled conditions. Impurities may result from the preparation process, such as sodium chloride, sodium sulfate, and sodium hydroxide.Formule :C10H11N4Na2O9PDegré de pureté :Min. 95%Couleur et forme :White Slightly Yellow PowderMasse moléculaire :408.17 g/molN4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
CAS :N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a diploid DNA molecule that is synthesized by the enzyme diploid. The clone was obtained from a yeast strain, and it has been shown to catalyze the conversion of isoprene to isopentenyl diphosphate. The optical spectra of this compound have been characterized in detail, and it has been found to have an absorption maximum at 243 nm. This compound has also been used in the disruption of yeast chromosomes, and its spectrum has been used as a reference for other compounds with similar chemical structures.Formule :C47H54N5O9PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :863.96 g/molN4-Benzoyl-2’-O-(2-ethoxyethyl)-5-methylcytidine
CAS :N4-Benzoyl-2’-O-(2-ethoxyethyl)-5-methylcytidine is an antiviral, monophosphate nucleoside. It is a novel anticancer agent that inhibits the synthesis of DNA and RNA in cells, and is a potent activator of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. N4-Benzoyl-2’-O-(2-ethoxyethyl)-5-methylcytidine has been shown to have high purity and high quality. It is synthesized by the reaction of 5′ phosphoramidite with 2’, 4′, 5′ benzoyl cytidine.Degré de pureté :Min. 95%2'-Deoxy-N2-isobutyrylguanosine
CAS :2'-Deoxy-N2-isobutyrylguanosine (2'-DIBG) is an inhibitor of bacterial translocation that has been shown to inhibit the growth of several bacterial species. This drug binds to fatty acids, which are important for maintaining the integrity of the cell membrane and preventing bacterial translocation. 2'-DIBG also inhibits the production of reactive oxygen species by bacteria, which contributes to its antimicrobial activity. Inflammation can be reduced by inhibiting prostaglandin synthesis with 2'-DIBG. The inhibition of prostaglandin synthesis may be due to its ability to form acid conjugates with fatty acids and dicarboxylic acids, which are precursors for prostaglandins. 2'-DIBG also inhibits the synthesis of adenosine triphosphate (ATP) in bacteria, leading to a decrease in bacterial growth rate.
Formule :C14H19N5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :337.34 g/molCaged GTP
CAS :Caged GTP is a modified nucleotide that is biologixally inactive until exposed to ultraviolet light, where GTP is released.Formule :C18H23N6O16P3Degré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :672.33 g/mol2'-Azido-2'-deoxycytidine
CAS :2'-Azido-2'-deoxycytidine is a nucleoside analog derived from cytidine, in which the 2'-hydroxyl group of the ribose is replaced by an azido group (–N₃), while the cytosine base and remaining sugar structure are preserved. This substitution imparts the molecule with bioorthogonal reactivity, enabling its use in chemical biology applications such as nucleic acid labeling via azide-alkyne "click" chemistry. The azido group also sterically and electronically alters sugar conformation and enzymatic recognition, which can affect its incorporation into DNA or RNA by polymerases. Consequently, 2'-azido-2'-deoxycytidine is a useful research tool.
Formule :C9H12N6O4Degré de pureté :Min. 95 Area-%Couleur et forme :Slightly Yellow PowderMasse moléculaire :268.2 g/molGuanosine 5'-diphosphate disodium salt
CAS :Guanosine 5'-diphosphate (GDP) disodium salt is a nucleoside dipsphate and a pyruvate kinase substrate, which converts GDP to GTP.Formule :C10H13N5O11P2·2NaDegré de pureté :Min. 90 Area-%Couleur et forme :White PowderMasse moléculaire :487.17 g/mol2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methyluridine
CAS :2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methyluridine is a nucleoside that is synthesized from 2’,3’,5’triphosphate and 5-methyluridine. It has been shown to be an activator of monophosphate synthesis in cells and to have anti-cancer properties. This compound is used in the synthesis of phosphoramidites for DNA sequencing.Degré de pureté :Min. 95%
