Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3573 produits trouvés pour "Nucléosides"
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3’-b-C-Methyl-5-methyluridine
CAS :3’-b-C-Methyl-5-methyluridine is a phosphoramidite that is used as an antiviral agent. It is also known as (2’,3’)-O-(2-methoxyethyl) 5'-O-(4,4'-dimethoxytrityl)thymidine or 3’-b-C-Methyluridine. It has been shown to have anticancer properties in vitro and in vivo, and it can be used for the treatment of prostate cancer. 3’-b-C-Methyluridine is synthesized by the reaction of uracil with bis(trimethylsilyl)acetamide followed by reaction with methylamine. The synthesis of this drug was first reported in 1975.Degré de pureté :Min. 95%7-Deaza-2'-deoxyinosine
CAS :7-Deaza-2'-deoxyinosine is a purine nucleoside analog that has been shown to be a hydrogen bond donor and formamide acceptor. This drug destabilizes duplex DNA by interfering with the formation of the hydrogen bonds between the bases, which may result in strand breakage. 7-Deaza-2'-deoxyinosine has also been shown to inhibit RNA polymerase activity, thereby inhibiting protein synthesis. It has been used as a tool for studying enzyme mechanisms and in solid phase synthesis.
Formule :C11H13N3O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :251.24 g/mol8-Azaadenosine
CAS :8-Azaadenosine is a purine nucleoside that is used as a template for DNA replication. The zwitterionic form of 8-Azaadenosine is found in plants and is converted to the charged form by enzymatic reactions. 8-Azaadenosine binds to the dna template strand and acts as a hydrogen bond donor, which stabilizes the transition state of the reaction and inhibits enzyme activity. This drug has been shown to affect polymerase chain reaction (PCR) by inhibiting DNA synthesis and it has been used in cancer cell lines with resistant mutants, such as Herpes simplex virus type 1 (HSV1).Formule :C9H12N6O4Degré de pureté :Min. 97 Area-%Couleur et forme :Off-White PowderMasse moléculaire :268.23 g/mol5’(R)-C-Methylguanosine
CAS :5’-C-Methylguanosine (5’-GMG) is a nucleoside that is the major product of viral RNA replication. It has been shown to be effective against tobacco mosaic virus and other plant viruses, including strains resistant to other nucleosides. 5’-GMG can be used in combination with other antiviral agents as an inoculant or as a systemic agent for treatment of plants infected with viruses. The sensitivity of cowpea chlorotic mottle virus to 5’-GMG was found to be dependent on the strain of the virus. Incubation of infected leaves with 5’-GMG resulted in a greater number of chlorotic lesions than incubation with water or uninfected leaves.Degré de pureté :Min. 95%7-Deaza-2'-deoxy-2'-fluoroguanosine
7-Deaza-2'-deoxy-2'-fluoroguanosine is a nucleoside that can be phosphorylated to form 7-deaza-2'-deoxy-2'-fluoroguanosine 5'-triphosphate. This compound has antiviral properties and may be used as an antiviral agent in the treatment of HIV/AIDS. 7DGTP inhibits HIV replication by inhibiting the reverse transcriptase enzyme. The mechanism by which this drug exerts its effects is not yet well understood, but it is believed that it binds to the active site of the enzyme and prevents it from hydrolyzing dNTPs.Formule :C11H14FN4O4Degré de pureté :Min. 95%Masse moléculaire :284.25 g/mol2'-C-Methylguanosine 5'-diphosphate triethylammonium salt
2'-C-Methylguanosine 5'-diphosphate triethylammonium salt is a synthetic nucleotide analog for use in researchFormule :C11H16N5O11P2·C18H45N3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :759.79 g/mol2'-Deoxycytidine-5'-monophosphate
CAS :2'-Deoxycytidine-5'-monophosphate (dCMP) is a nucleotide that is synthesized by the enzyme cytidine monophosphate synthetase. It has been shown to inhibit the activity of many enzymes, including those involved in DNA synthesis and repair. The incorporation of dCMP into DNA can be used as a probe for studying various biological processes, such as radiation damage and cellular physiology. In addition, it has been shown that dCMP inhibits the growth of human osteosarcoma cells. This drug is also used in combination preparations with other drugs, such as with 5-fluorouracil and doxorubicin, to treat cancer tumors.Formule :C9H14N3O7PDegré de pureté :Min. 99 Area-%Couleur et forme :White PowderMasse moléculaire :307.2 g/mol3'-Deoxy-2'-C-methyluridine
CAS :3'-Deoxy-2'-C-methyluridine is a nucleoside with antiviral, anticancer and deoxyribonucleoside properties. It is a synthetic nucleoside that can be activated to form a monophosphate or diphosphate. It has been shown to inhibit the replication of DNA and RNA viruses in vitro. 3'-Deoxy-2'-C-methyluridine has also been shown to induce apoptosis in cancer cells and inhibit tumor growth in vivo.Degré de pureté :Min. 95%2'-O-Allylcytidine
CAS :2'-O-Allylcytidine is a synthetic nucleotide that contains an allylated amino function. It is synthesized by the regiospecific allylation of uridine and guanosine. 2'-O-Allylcytidine has been used in research studies for the synthesis of oligonucleotides with specific sequences and for high-yield production of synthons.Formule :C12H17N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :283.28 g/molE-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine
CAS :E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is a nucleoside that is a modified form of uridine. It is a nucleotide analog that inhibits the synthesis of DNA and RNA and can be used to treat cancer. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is an activator that activates the phosphoramidites in the synthesis of DNA and RNA. This drug can also be used as antiviral therapy for herpes simplex virus type 1, influenza virus, and HIV. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis.Formule :C13H16N2O7Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :312.28 g/mol2-Chloro-9-(b-D-ribofuranosyl)purine
CAS :2-Chloro-9-(b-D-ribofuranosyl)purine is a monophosphate nucleoside that has been shown to have antiviral and anticancer activity. It is synthesized through the chemical conversion of 2,4-dichloropyrimidine with b-D-ribofuranose. This product is a novel nucleoside analogue that has been shown to be an activator of DNA synthesis. In addition, 2-chloro-9-(b-D ribofuranosyl) purine may be used as a phosphoramidite for oligonucleotide synthesis.Degré de pureté :Min. 95%(E)-5-(2-Carboxyvinyl)-2'-deoxyuridine
CAS :(E)-5-(2-Carboxyvinyl)-2'-deoxyuridine is a nucleoside for a range of applicationsFormule :C12H14N2O7Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :298.25 g/molOleoyl coenzyme A
CAS :Oleoyl coenzyme A is an acyl-coa that is synthesized from oleic acid. Its synthesis is regulated by transcriptional factors. The enzyme ATP-binding cassette transporter transports the oleoyl coenzyme A to the endoplasmic reticulum, where it is converted to caprylic acid by synthetase. Caprylic acid is then transported back to the cytosol, where it can be converted into other compounds. Oleoyl CoA has been shown to regulate cellular metabolism and energy production in the liver, which may be related to its ability to prevent hepatic steatosis and reduce cancer tissues. Oleoyl CoA also has a role in regulating the activity of various enzymes in cells through a polymerase chain reaction (PCR) technique.Formule :C39H68N7O17P3SDegré de pureté :Min. 95%Masse moléculaire :1,031.98 g/mol5'-O-Benzyl-N2-DMF-2'-deoxyguanosine
5'-O-Benzyl-N2-DMF-2'-deoxyguanosine is a deoxyribonucleoside that is synthesized from 5'-O-benzyl-N2,N4-dimethoxypyridinium chloride and 2'-deoxyguanosine. It is a novel anticancer and antiviral agent that has shown to be more active than other analogues in inhibiting the growth of human cancer cells in culture. The drug has also been shown to inhibit the replication of herpes simplex virus type 1 (HSV1) in animal models. 5'-O-Benzyl-N2,N4-dimethoxypyridinium chloride was used as the precursor for this drug, which can be prepared by reacting benzaldehyde with dimethoxypyrimidine.Formule :C20H24N6O4Degré de pureté :Min. 95%Masse moléculaire :412.44 g/mol2’,3’-Bis-O-tert-butyldimethylsilyl-5’-deoxy-4’,5’-Didehydrouridine
CAS :2’,3’-Bis-O-tert-butyldimethylsilyl-5’-deoxy-4’,5’-Didehydrouridine is a phosphoramidite that is used in the synthesis of DNA, RNA and nucleotide analogues. It has antiviral and antitumor properties and can be used for the treatment of leukemia. 2’,3’-Bis-O-tert-butyldimethylsilyl-5’-deoxyuridine is an activator for ribonucleotides and deoxyribonucleotides. It also has anticancer properties due to its ability to inhibit DNA replication, which may lead to apoptosis or cell death.Degré de pureté :Min. 95%2'-Deoxy-5-propynylcytidine
CAS :Deoxynucleoside with an alkyne handle on the base which can be used for conjugation via click chemistry.Formule :C12H15N3O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :265.27 g/mol3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine
CAS :3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine is an antiviral drug. It is a modified nucleoside with phosphoramidite and azido groups. This product can be used as an activator for DNA synthesis, in anticancer drug development, as well as in the treatment of HIV. 3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine has been shown to inhibit the growth of human tumor cells by inhibiting protein synthesis and enhancing the production of reactive oxygen species (ROS). It also inhibits the activity of ribonucleotide reductase, which is a critical enzyme for DNA synthesis.Degré de pureté :Min. 95%Cytidine 2',3'-cyclic monophosphate monosodium
CAS :Cytidine 2',3'-cyclic monophosphate monosodium salt is a nucleotide that is used in the synthesis of DNA and RNA. It has antiviral and anticancer properties. Cytidine 2',3'-cyclic monophosphate monosodium salt is a high purity, high quality nucleotide with strong activator properties. It is also an excellent substrate for DNA polymerases, which may be due to its ability to bind to the phosphate groups on the enzyme's active site. This product can be used as a phosphoramidite during DNA synthesis or as an antiviral agent that inhibits viral replication by inhibiting the formation of viral DNA.Formule :C9H11N3O7P•NaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :327.16 g/mol5'-O-Methyl-D3-thymidine
Produit contrôlé5'-O-Methyl-D3-thymidine is a synthetic nucleoside that has been modified to contain a methyl group at the 5' position. It is used in the synthesis of DNA and RNA, as well as in the preparation of phosphoramidites for oligonucleotide synthesis. This nucleoside has antiviral and anticancer properties and may be useful for treating diseases such as AIDS, hepatitis B, and leukemia. The compound can also act as an activator during polymerase chain reactions. 5'-O-Methyl-D3-thymidine is readily soluble in water and in organic solvents and is highly pure with a high yield of 99%.Formule :C11H13N2O5D3Degré de pureté :Min. 95%Masse moléculaire :259.27 g/mol2'-Deoxy-2'-fluoro-L-uridine
CAS :2'-Deoxy-2'-fluoro-L-uridine is a synthetic nucleoside analog of uridine where the sugar is both fluorinated at the 2' position and in the L-configuration, which is the mirror image of naturally occurring D-nucleosides. This modification makes it structurally distinct and biologically significant for certain applications in drug development and biochemical research.
Formule :C9H11FN2O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :246.2 g/mol
