Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3571 produits trouvés pour "Nucléosides"
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[1,2,4]Triazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS :[1,2,4]Triazolo[1,5-a]pyrimidine-2-carboxylic acid is a heterocyclic compound made up of a pyrimidine ring and a triazole ring. It can be used in research applicationsFormule :C6H4N4O2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :164.12 g/mol3,5-Dichloro-4-pyridone-1-acetic acid
CAS :3,5-Dichloro-4-pyridone-1-acetic acid is a chlorinated derivative of 7-aminocephalosporanic acid that is synthesized from hydrochloric acid and chloroacetic anhydride. It is used in the pharmaceutical industry as a reagent to produce medicines such as antibiotics and anti-inflammatory agents. The product yield of this reaction is high, which makes it an excellent choice for industrial use. 3,5-Dichloro-4-pyridone-1-acetic acid also has a low toxicity profile and can be easily degraded by bacteria in the environment.Formule :C7H5Cl2NO3Degré de pureté :Min. 95%Masse moléculaire :222.02 g/mol2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt
CAS :2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt is a prodrug that is converted to fluorouracil in the body. Fluorouracil inhibits the activity of thymidylate synthase and other enzymes involved in DNA synthesis, which are associated with cancer. It is also an inhibitor binding to the enzyme RNA polymerase II, which may contribute to its anti-cancer effects. 2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt has been shown to inhibit the growth of human tumor cells in culture and in animal models. The matrix effect may be responsible for this activity. 2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt can be used as a model system for studying cancer tissues.Formule :C9H12FN2O8P·xNaDegré de pureté :Min. 85 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :326.17 g/mol9-(2',3',5'-Tri-O-benzoyl-2'C-methyl-b-D-ribofuranosyl)purine
CAS :9-(2',3',5'-tri-O-benzoyl-2'C-methyl-β-D-ribofuranosyl)purine is a nucleoside that was synthesized and patented in 1993. It is a novel modified nucleoside with antiviral, anticancer, and DNA activating properties. 9-(2',3',5'-tri-O-benzoyl-2'C-methyl-β-D-ribofuranosyl)purine has been shown to inhibit HIV replication by inhibiting the viral reverse transcriptase enzyme. It also inhibits the growth of human cancer cells in culture and has been studied as an anticancer drug. This nucleoside is a substrate for ribonucleotide reductase and phosphoramidite synthase, which convert it into its monophosphate form. The monophosphate form can be converted into the triphosphate form by phosphatases or polymerasesDegré de pureté :Min. 95%2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine 3'-CE phosphoramidite
CAS :2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine 3'-CE phosphoramidite is a novel antiviral agent that inhibits the synthesis of DNA, RNA, and proteins. It is synthesized by the reaction of 5-fluoro-2'-deoxyuridine with 2',3' -dideoxyadenosine 5'-O-(4,4'-dimethoxytrityl)-3',5' -cyanoethyl phosphate in an organic solvent. The product is purified by column chromatography and crystallized from ethyl acetate. 2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine 3'-CE phosphoramidite has been shown to be an anticancer agent against breast cancer cells in vitro and in vivo.Formule :C40H48FN4O8PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :762.82 g/mol5-Chloro-2-pyridinecarboxylic acid methyl ester
CAS :5-Chloro-2-pyridinecarboxylic acid methyl ester is a monophosphate nucleoside that can be used in the synthesis of DNA and RNA. It is also an antiviral, anticancer, and anticoagulant agent. 5-Chloro-2-pyridinecarboxylic acid methyl ester has been shown to inhibit DNA replication and transcription by inhibiting the activity of enzymes involved in these processes. It can be used as a building block for the synthesis of DNA and RNA. The purity of this product is high, with no detectable impurities at levels above 0.1%.Formule :C7H6ClNO2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :171.58 g/mol2’,3’,5’-Tri-O-benzoyl-5-difluoromethyluridine
CAS :2’,3’,5’-Tri-O-benzoyl-5-difluoromethyluridine is a novel modified nucleoside. It is a high quality monophosphate that can be used as an activator for DNA synthesis. This compound has shown anticancer activity in various cell lines and has antiviral properties. It can be used as a phosphoramidite for the synthesis of oligonucleotides. 2’,3’,5’-Tri-O-benzoyl-5-difluoromethyluridine is synthesized by using 5'-DMT-2',3',5' -triphosphate as the starting material. The diphosphate is then oxidized to form the corresponding triphosphate (the active form).Formule :C31H24F2N2O9Degré de pureté :Min. 95%Masse moléculaire :606.53 g/mol3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)cytidine
CAS :Used as a protected cytidine nucleoside in RNA synthesis. Similar to its adenosine counterpart, the 1,1,3,3-tetraisopropyl-1,3-disiloxanediyl (TIPDS or TBDPSi2) group serves as a bulky and selectively acid-labile protecting group for the 3' and 5' hydroxyl groups of the cytidine ribonucleoside during RNA oligonucleotide synthesis.Formule :C21H39N3O6Si2Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :485.72 g/molUridine-2',3'-cyclic monophosphate sodium salt
CAS :Uridine-2',3'-cyclic monophosphate sodium salt (CAS No. 15718-50-0) is a novel anticancer agent that has been shown to inhibit the growth of cancer cells in vitro and in vivo. It is a nucleoside analog that inhibits the synthesis of DNA by inhibiting ribonucleotide reductase and deoxyribonucleotide reductase, two enzymes involved in the production of DNA. Uridine-2',3'-cyclic monophosphate sodium salt is also an antiviral agent used to treat herpesvirus infections, such as herpes simplex type 1 and 2. This drug binds to viral RNA polymerase, which prevents viral replication by preventing mRNA synthesis.Formule :C9H10N2NaO8PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :328.15 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-thiophosphoramidite
2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-thiophosphoramidite is a novel antiviral agent that inhibits the replication of viruses. It acts by competitively inhibiting the activity of viral DNA polymerase, preventing the addition of nucleotides to the growing DNA strand and thereby halting viral replication. This product is a deoxyribonucleoside monophosphate that is synthesized from an antiviral ribonucleoside monophosphate. 2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-thiophosphoramidite has been shown to have anticancer properties in vitro. It also has immunostimulating effects, which may be due to its ability to activate cells involved in immune responses.Formule :C48H53N6O8PS2Degré de pureté :Min. 95%Masse moléculaire :937.08 g/mol2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-fluorouridine
CAS :2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-fluorouridine is a nucleoside that inhibits the synthesis of RNA by inhibiting the enzyme RNA polymerase. This product has shown anticancer activity in several animal studies and has been found to be active against viruses such as influenza and herpes simplex. 2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-fluorouridine is an extremely potent inhibitor of HIV replication with a much lower cytotoxicity in comparison to other antiviral drugs. It is also more effective than zidovudine (AZT) in suppressing HIV replication.Degré de pureté :Min. 95%9-(2',3',5'-Tri-O-acetyl-β-D-ribofuranosyl)-6-chloropurine
CAS :9-(2',3',5'-Tri-O-acetyl-b-D-ribofuranosyl)-6-chloropurine is an anticancer drug that belongs to the class of nucleosides. It is a modified nucleoside with a 2'-deoxyribose sugar and a 6-chloropurine base. The synthesis of 9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-6-chloropurine can be achieved by phosphoramidite chemistry. Modified nucleosides have been found to have high antiviral and antitumour activities, as well as being promising for the treatment of HIV infections. 9-(2',3',5'-tri-O acetyl b D ribofuranosyl)-6 chloropurine has also been shown to inhibit the replication of RNA in cells infected with HIV, although it has not yet been used in humans.Formule :C16H17ClN4O7Degré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :412.78 g/molRibavirin 5'-diphosphate lithium
CAS :Ribavirin is an antiviral drug that inhibits the production of viral RNA. Ribavirin 5'-diphosphate is formed in the liver through sequential actions of kinases.Formule :C8H14N4O11P2•Li2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :418.03 g/molN4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine
CAS :N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is a novel nucleoside that was synthesized by converting the ribonucleoside 5'-O-DMT to its deoxyribonucleoside form. N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is an antiviral and antiproliferative agent that inhibits DNA synthesis. It also has anticancer activity, but does not have any effect on RNA synthesis. This product is available in high quality and high purity with CAS No. 171486-51-4.Formule :C41H37N5O7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :711.76 g/mol2',3',5'-Tri-O-benzoyl-2'-C-methylcytidine
CAS :2',3',5'-Tri-O-benzoyl-2'-C-methylcytidine is a modified cytidine analog. Cytidine is a pyrimidine nucleoside, composed of cytosine attached to a ribose sugar via a β-glycosidic bond. The hydroxyl groups on the ribose sugar at the 2′, 3′, and 5′ positions are protected with benzoyl groups which can prevent side reactions during chemical synthesis. A methyl group is also added to the 2′ carbon of the sugar ring.Formule :C31H27N3O8Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :569.56 g/mol1-(2’,3’,5’-Tri-O-benzyl-4’-thio-b-D-arabinofuranosyl)uracil
CAS :Ribonucleosides are a type of nucleoside that contains ribose sugar in its structure. Ribonucleosides have been synthesized from 1-(2’,3’,5’-tri-O-benzyl-4’-thio-b-D-arabinofuranosyl)uracil using phosphoramidites. These compounds are novel nucleosides and deoxyribonucleosides with the potential to be used as anticancer agents and antiviral drugs. Ribonucleosides can also act as activators for DNA polymerases, which may be useful in the treatment of cell proliferation disorders. They are modified nucleotides that are high purity, high quality and CAS No. 267665-69-0.Degré de pureté :Min. 95%Thymidine-5'-diphosphate-D-viosamine disodium salt
CAS :Thymidine-5'-diphosphate-D-viosamine disodium salt is a nucleoside that has been conjugated to a carrier molecule. This compound is an anomeric, pyranose, and conjugate acid. It has been shown to have antiviral activity in vitro and in vivo against herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and human cytomegalovirus (CMV). Thymidine-5'-diphosphate-D-viosamine disodium salt inhibits the synthesis of viral DNA by inhibiting the incorporation of uracil into the viral DNA strand. This inhibition prevents the production of new viruses by preventing replication.Formule :C16H25N3O14P2Na2Degré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :591.31 g/mol3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine
CAS :3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine is a nucleoside monophosphate with antiviral activity. It is a synthetic nucleoside that has been modified to be resistant to degradation by ribonucleases. 3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine inhibits the synthesis of DNA, RNA and protein and is used for treatment of cancer. This drug is not active against other types of viruses such as herpes simplex virus or cytomegalovirus.
Formule :C13H15FN2O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :330.27 g/mol3'-Amino-2',3'-dideoxy-5'-O-DMT-N2-isobutyrylguanosine
a specifically designed building block for introducing a 3'-amino group into oligonucleotides. The dideoxy sugar ensures the amino group is the primary functionality at the 3' end, while the DMT and isobutyryl protecting groups ensure controlled reactivity during oligonucleotide synthesis and subsequent modification steps.Formule :C35H38N6O6Degré de pureté :Min. 95%Masse moléculaire :638.71 g/mol5’-Azido-5’-deoxy-2’-O,4’-C-methyleneuridine
CAS :5’-Azido-5’-deoxy-2’-O,4’-C-methyleneuridine is a novel modified nucleoside that is phosphorylated to the 5′ position. It can be used as a purine analogue in the synthesis of DNA and RNA. This compound has antiviral activity, which may be due to its ability to inhibit viral DNA polymerase and/or viral RNA polymerase. 5’-Azido-5’-deoxy-2’-O,4’-C methyleneuridine also has anticancer properties by inhibiting DNA synthesis and cell division.Formule :C10H11N5O5Degré de pureté :Min. 95%Masse moléculaire :281.22 g/mol
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