Nucléosides
3570 produits trouvés pour "Nucléosides"
3'-Azido-3'-deoxy-5'-O-tritylthymidine
CAS :An intermediate in the production of Zidovudine, the FDA approved medication for treatment of AIDS.Formule :C29H27N5O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :509.56 g/mol2',3'-Dideoxyguanosine-5'-triphosphate
CAS :2',3'-Dideoxyguanosine-5'-triphosphate (ddGTP) is a nucleotide analog that inhibits the formation of DNA and RNA, which are important for protein synthesis. It is used in clinical studies to assess prognosis and to evaluate drug elimination. ddGTP has been shown to inhibit mitochondrial membrane potential, decrease mitochondrial superoxide, and inhibit cancer growth. It also prevents allergic reactions by preventing the release of histamine. The use of probiotic bacteria containing ddGTP may help in the treatment of inflammatory bowel disease.Formule :C10H14N5O6PDegré de pureté :Min. 95%Masse moléculaire :331.22 g/mol5'-O-DMT-thymidine-3'-lcaa-CPG
5'-O-DMT-thymidine-3'-lcaa-CPG is a nucleoside, ribonucleoside, and diphosphate that inhibits viral DNA synthesis. It is a novel compound with antiviral properties that has been shown to inhibit the replication of human cytomegalovirus (HCMV) and herpes simplex type 1 virus. 5'-O-DMT-thymidine-3'-lcaa-CPG also functions as an anticancer agent by inhibiting DNA synthesis in tumor cells. This nucleoside analog is phosphoramidite, which can be used for the preparation of modified oligonucleotides. 5'-O-DMT-thymidine-3'-lcaa-CPG has high purity and high quality.Degré de pureté :Min. 95%Couleur et forme :Powder5-Hydroxy-DC CEP
CAS :Please enquire for more information about 5-Hydroxy-DC CEP including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C53H56N5O10PDegré de pureté :Min. 95%Masse moléculaire :954 g/mol5'-O-DMT-N2-isopropylphenoxyacetyl-2'-O-(2-methoxyethyl)guanosine 3'-O succinate TEA salt
5'-O-DMT-N2-isopropylphenoxyacetyl-2'-O-(2-methoxyethyl)guanosine 3'-O succinate TEA salt is a modified nucleoside with anticancer activity. It is a diphosphate that can be used for the synthesis of DNA and RNA. This product is synthesized by the reaction of 5'-O-dimethoxytritylthymidine (5'-DMTT), 2'-O-(2-methoxyethyl)hydroxylamine hydrochloride, and succinic anhydride in the presence of triethylamine. The product is purified by column chromatography, followed by recrystallization from hot acetonitrile. CAS No.: 102972-73-0Formule :C49H52N5O13·C6H16NDegré de pureté :Min. 95%Masse moléculaire :1,021.16 g/mol7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine
CAS :7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a diphosphate nucleoside analogue that can be activated by phosphoramidites. It is a novel, synthetic, and high quality nucleotide with antiviral and anticancer properties. This drug has been shown to inhibit the synthesis of DNA and RNA at the transcriptional level. 7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a monophosphate nucleoside analogue that can be used in ribonucleotide synthesis for the treatment of cancer.Formule :C16H16F3N5O3Masse moléculaire :383.33 g/molRef: 3D-J-700297
-Unit-ggÀ demander1gÀ demander50mgÀ demander100mgÀ demander250mgÀ demander500mgÀ demander5’-Deoxy-5’-iodouridine
CAS :5’-Deoxy-5’-iodouridine (5DIU) is an antiviral agent that inhibits the synthesis of DNA by interfering with the enzyme thymidine kinase, which converts thymine to uracil. It is used in the treatment of cutaneous herpes simplex virus infections. 5DIU has been shown to inhibit viral replication and yield in vitro. The drug showed no significant toxicity in mice, rats, or hamsters. In addition, it has been observed that 5DIU does not interfere with human cell growth, which may be due to its lack of activity against a wide range of human enzymes.Degré de pureté :Min. 95%Gemcitabine 5'-elaidate
CAS :Gemcitabine 5'-elaidate is an analog of gemcitabine that has hydrophobic properties. It has been shown to be active against solid tumours, including lung cancer. In a study on murine xenografts, gemcitabine 5'-elaidate was found to have the same degree of efficacy as gemcitabine in reducing tumour growth and increasing survival time. Gemcitabine 5'-elaidate also has good antitumour activity against infectious diseases such as HIV and malaria, which may be due to its ability to bind to the epidermal growth factor receptor (EGFR) on the surface of cells. This binding prevents EGFR from initiating cellular signaling.
Formule :C27H43F2N3O5Degré de pureté :Min. 95%Masse moléculaire :527.66 g/mol2-Amino-4-(thien-2-yl)pyrimidine
CAS :2-Amino-4-(thien-2-yl)pyrimidine is a bioavailable, water soluble antiallergy drug. 2-Amino-4-(thien-2-yl)pyrimidine has been shown to be effective against allergic asthma and other allergic diseases. It is thought to work by blocking the release of histamine from mast cells, thereby preventing the production of inflammatory prostaglandins and leukotrienes. This drug also blocks the response to allergies by inhibiting the release of IgE antibodies that bind to allergens. The therapeutic effect of 2-amino-4-(thien-2-yl)pyrimidine is repeatable and it does not cause any adverse effects on potassium or carbonate metabolism.Formule :C8H7N3SDegré de pureté :Min. 95%Masse moléculaire :177.23 g/molAMP PNP tetralithium salt
CAS :Non-hydrolyzable AMP analog
Formule :C10H13Li4N6O12P3Degré de pureté :Min. 95%Masse moléculaire :529.93 g/mol5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide
CAS :5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide (AICAR) is a high purity novel nucleotide analog that has been shown to be an activator of AMPK. AICAR can act as a substitute for ATP, the molecule that drives cellular energy production. AICAR has been shown to inhibit tumor growth and induce apoptosis in cancer cells. This compound also inhibits viral RNA replication by competitively binding to the enzyme polymerase, which is essential for viral replication.
Formule :C15H20N4O8Degré de pureté :Min. 95%Masse moléculaire :384.34 g/mol3'-Deoxy-3'-C-methyluridine
CAS :3'-Deoxy-3'-C-methyluridine is a novel and modified nucleoside that is synthesized from uridine. It is a monophosphate and has been shown to be an activator of the mammalian enzyme ribonucleotide reductase. 3'-Deoxy-3'-C-methyluridine has also been shown to have antiviral effects, as well as anticancer activity in studies with mice. The high purity and high quality of this product make it ideal for use in research, pharmaceuticals, and other applications.Formule :C10H14N2O5Degré de pureté :Min. 95%Masse moléculaire :242.23 g/molRibavirin 5'-monophosphate sodium salt
CAS :Ribavirin is an antiviral drug that is used in the treatment of a number of viral infections, including chronic hepatitis C, respiratory syncytial virus, and influenza. Ribavirin inhibits the synthesis of RNA by interfering with ribonucleotide reductase. Ribavirin 5'-monophosphate sodium salt (RPMPS) is a prodrug that is hydrolyzed to form ribavirin 5'-triphosphate (RTP). This active form inhibits the polymerase chain reaction by binding to DNA polymerase. Ribavirin has been shown to be effective against cell lines resistant to other antiviral drugs such as zirconium oxide. RPMPS has also been shown to be an inhibitor of structural analysis and energy metabolism in erythrocytes.Formule :C8H13N4O8P·xNaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :324.18 g/mol5'-O-DMT-cytidine
CAS :5'-O-DMT-cytidine is a modified nucleoside that is used as an activator for phosphoramidites and as a building block for DNA, RNA, and other nucleic acids. 5'-O-DMT-cytidine has been shown to have anticancer and antiviral properties in laboratory tests. It is also known to inhibit the replication of HIV virus by blocking the reverse transcriptase enzyme. The compound is available with high purity and high quality. This product can be synthesized into a diphosphate, monophosphate or ribonucleotide form.
Formule :C30H31N3O7Degré de pureté :Min. 95%Masse moléculaire :545.58 g/molS-Adenosyl-L-methionine
CAS :S-Adenosyl-L-methionine (SAM-e) is a co-substrate involved in methyl group transfer to nucleic acids, proteins and lipids. SAM-e is produced in the liver from adenosine triphosphate (ATP) and methionine by action of the enzyme methionine adenosyltransferase. Therapeutic use of S-adenosyl-L-methionine includes osteoarthritis, liver disease and major depressive disorder. S-Adenosyl-L-methionine is available as a dietary supplement.Formule :C15H22N6O5SDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :398.44 g/mol1-Hydroxyethyl-2'-deoxyadenosine
CAS :1-Hydroxyethyl-2'-deoxyadenosine (1HEDA) is an antiviral drug that inhibits the synthesis of viral DNA by blocking the formation of a ribonucleoside triphosphate intermediate. 1HEDA is a novel monophosphate nucleoside that has been modified to be resistant to phosphodiesterase enzymes and can be used as a chemotherapeutic agent for cancer. 1HEDA has been shown to have anticancer activity in vitro, in vivo, and in human clinical trials.Formule :C12H17N5O4Degré de pureté :Min. 95%Masse moléculaire :295.29 g/molGuanosine 5'-[γ-thio]triphosphate tetralithium
CAS :Guanosine 5'-[γ-thio]triphosphate tetralithium (GTPγS) is a guanine nucleotide analog that has been shown to modulate the signal transduction pathway in many types of cells. GTPγS activates the extracellular signal-transducing receptor kinase and phospholipase C, which are involved in cellular proliferation and differentiation. This agent also blocks calcium channels, thereby inhibiting neuromuscular transmission. It has been shown to be effective against pertussis toxin and other agents that block G protein coupling by inhibiting adenylate cyclase. In addition, GTPγS inhibits staurosporin-sensitive K+ channels in some neuronal cells, but not those that are insensitive to this blocker.Formule :C10H12Li4N5O13P3SDegré de pureté :Min. 90 Area-%Couleur et forme :PowderMasse moléculaire :562.98 g/molGuanylyl-3'-5'-uridine ammonium salt
CAS :Guanylyl-3'-5'-uridine ammonium salt is a nucleoside compound that has been synthesized to inhibit the growth of cancer cells. The guanylyl-3'-5'-uridine monophosphate (GMP) is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. It also inhibits DNA synthesis by inhibiting the activity of DNA polymerase and DNA gyrase, which are enzymes that maintain the integrity of DNA. Guanylyl-3'-5'-uridine ammonium salt has been shown to be active against leukemia and colon cancer cells in vitro and in vivo.
Formule :C19H24N7O13P·NH3Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :606.45 g/molUridylyl-3'-5'-guanosine ammonium salt
Ribonucleosides are a group of nucleosides that includes ribose, 2'-deoxyribose, and their derivatives. Ribonucleosides are the building blocks of DNA and RNA. Uridylyl-3'-5'-guanosine ammonium salt is a novel monophosphate nucleotide with antiviral properties. It has been shown to inhibit the synthesis of viral proteins by binding to viral dsDNA and preventing them from being transcribed into mRNA. This drug is also an activator that increases the activity of RNA polymerase II during transcription initiation. The high purity and quality make Uridylyl-3'-5'-guanosine ammonium salt suitable for use in research or as a pharmaceutical ingredient for the manufacture of other drugs.Formule :C19H24N7O13PDegré de pureté :Min. 95%Masse moléculaire :589.41 g/molgamma-(BBT)-GTP
gamma-(BBT)-GTP is a synthetic nucleoside phosphoramidite that is used in the synthesis of DNA and RNA. It has antiviral properties and can be used as an activator of DNA polymerase in the deoxyribonucleotide synthesis. This chemical is novel because it can be modified to contain a phosphate group at the 2'-position, which is not found in natural nucleosides or nucleotides. gamma-(BBT)-GTP is a high-purity chemical that can be synthesized using CAS No. 72335-45-2.
Formule :C24H22N7O14P3S2·xNaDegré de pureté :Min. 95%Masse moléculaire :789.52 g/mol
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