
Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3567 produits trouvés pour "Nucléosides"
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Cytidine 5'-triphosphate disodium dihydrate
CAS :<p>Cytidine 5'-triphosphate (CTP) disodium dihydrate prevents the action of aspartate carbamoyltransferase, an enzyme involved in pyrimidine biosynthesis. CTP serves as a molecule of high energy and acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.</p>Formule :C9H16N3O14P3•(H2O)2•Na2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :565.17 g/molN4-Etheno 2'-deoxycytidine
CAS :<p>N4-Etheno 2'-deoxycytidine is an aromatic hydrocarbon that has been shown to be a potent inhibitor of DNA synthesis. It binds covalently with the N4 position of deoxycytidine in DNA, thereby inhibiting transcription and replication. This drug has been shown to be a potent inhibitor of DNA synthesis in human cells when it is added to the culture medium, but it does not inhibit protein synthesis. N4-Etheno 2'-deoxycytidine can also react with hydrogen bonds in cellular proteins and nucleosides that are involved in DNA repair mechanisms. This drug is reactive and may cause oxidative damage to cellular components, which may lead to carcinogenesis.</p>Formule :C11H13N3O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :251.24 g/molPolyguanylic acid potassium
CAS :<p>Polyguanylic acid potassium salt is a guanosine analog that is used as a probe for studying the interaction of cellular and target tissue. It has been found to be taken up by cells, with high affinity constants, and to be immobilized on cell surfaces. Polyguanylic acid potassium salt can also be used as an anticancer agent against epidermoid carcinoma cells with high affinity constants. The compound interacts with DNA and inhibits the growth of the tumor cells by interfering with the uptake of nucleic acids.</p>Formule :(C10H14N5O8P)x•KxDegré de pureté :Min. 95%Couleur et forme :Powder2'-Phosphoadenosine 5'-phosphosulfate tetralithium salt (mixture with 3'-isomer)
CAS :<p>2'-Phosphoadenosine 5'-phosphosulfate tetralithium salt (mixture with 3'-isomer) is a novel, modified nucleoside. It has antiviral properties and can be used for the treatment of cancer. 2'-Phosphoadenosine 5'-phosphosulfate tetralithium salt (mixture with 3'-isomer) inhibits viral replication by inhibiting the synthesis of viral DNA and RNA. This compound also inhibits cancer cell proliferation by inhibiting deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) synthesis.</p>Formule :C10H11N5O13P2S·4LiDegré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :531 g/molCyclic inosine diphosphate ribose
CAS :<p>Cyclic inosine diphosphate ribose is a synthetic, fluorescent compound that can be used as a probe for assays. It has been synthesized by the solid-phase synthesis of a specific antibody and is bioconjugated with an oligo(ethylene glycol) moiety. Cyclic inosine diphosphate ribose can be used to measure lymphocyte activation, which is important for the study of autoimmune diseases and cancer. Cyclic inosine diphosphate ribose has also been shown to bind to the ryanodine receptor, which causes an increase in intracellular calcium concentration.</p>Formule :C15H20N4O14P2Degré de pureté :Min. 95%Masse moléculaire :542.29 g/mol(E)-2'-Deoxy-2'-(fluoromethylene)cytidine
CAS :<p>(E)-2'-Deoxy-2'-(fluoromethylene)cytidine is a cytostatic compound that inhibits DNA synthesis in tumor cells. It has been shown to be more potent than tezacitabine and hl-60 cells, as well as being less toxic than benzimidazole compounds. This analog of cytosine has been shown to have potent antitumor activity against carcinoma cell lines and myeloid leukemia cell lines. The oral prodrug form of this drug has been shown to be an effective treatment for myeloid leukemia in mice.</p>Formule :C10H12FN3O4Degré de pureté :Min. 95%Masse moléculaire :257.22 g/molMyristoyl coenzyme A
CAS :<p>Myristoyl coenzyme A is a potential drug that inhibits the binding of human pathogens to protein. It also has been shown to have potential as an inhibitor for reactions involving myristoylation, which is a process where proteins are modified with myristic acid. Myristoyl coenzyme A was synthesized using titration calorimetry and in vitro assays. The compound has been shown to have the ability to inhibit polymerase chain reaction (PCR) and reduce the growth of bacteria in vitro. Myristoyl coenzyme A may be useful in treating metabolic disorders and infectious diseases such as AIDS, tuberculosis, and malaria.</p>Formule :C35H62N7O17P3S·H2ODegré de pureté :Min. 90%Couleur et forme :White PowderMasse moléculaire :995.91 g/molNicotinic acid adenine dinucleotide sodium
CAS :<p>Nicotinic acid adenine dinucleotide sodium (NAAD) is a novel anticancer and antiviral agent. NAAD is an analog of nicotinamide adenine dinucleotide (NAD) that has been modified to include a sodium ion. This modification inhibits the synthesis of DNA and RNA, which are required for cell division and replication. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. In addition, NAAD suppresses viral replication by inhibiting protein synthesis in cells infected with HIV-1 or influenza virus. NAAD has also been shown to be a potent inhibitor of ribonucleoside reductase, which converts ribonucleosides into deoxyribonucleosides. This inhibition prevents the conversion of diphosphate nucleotides into monophosphate nucleotides, which are necessary for DNA synthesis.</p>Formule :C21H26N6O15P2•NaDegré de pureté :Min. 95%Masse moléculaire :687.4 g/mol5-Formylamino-4-imidazolecarboxamide ribonucleotide
CAS :<p>5-Formylamino-4-imidazolecarboxamide ribonucleotide is a nucleoside that is synthesized from 5-aminoimidazole ribonucleotide. It has antiviral and anticancer properties and is used as a precursor for the synthesis of other nucleosides. 5-Formylamino-4-imidazolecarboxamide ribonucleotide can be used in the preparation of oligodeoxyribonucleotides, which are involved in DNA replication, transcription, and translation. This compound also has been shown to inhibit the growth of cells with HIV or cancerous cells.</p>Formule :C10H15N4O9PDegré de pureté :(Elemental Analysis) Min. 85%Masse moléculaire :366.22 g/molN6-Hydroxymethyladenosine
CAS :<p>Please enquire for more information about N6-Hydroxymethyladenosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C11H15N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :297.27 g/molLevovirin
CAS :Produit contrôlé<p>Applications Levovirin is a monocyclic L-nucleosides with type 1 cytokine-inducing activity. Levovirin is the L-enantiomer of Ribavirin (R414475) with similar immunomodulatory activity but does not have direct antiviral activity or hemolytic anemia.<br>References Ramasamy, K.S. et al.: J. Med. Chem., 43, 1019 (2000); Fang, C. et al.: J. Appl. Toxicol., 23, 453 (2003):<br></p>Formule :C8H12N4O5Couleur et forme :NeatMasse moléculaire :244.20N-Succinyl-5-aminoimidazole-4-carboxamide ribose 5'-phosphate
CAS :<p>N-Succinyl-5-aminoimidazole-4-carboxamide ribose 5'-phosphate is a synthetase that is involved in the biosynthesis of purines and pyrimidines. It catalyzes the ATP-dependent formation of N-succinyl5'-aminoimidazole-4-carboxamide ribose 5'-phosphate from succinyl CoA and aspartic acid. This enzyme has been studied in wild type strains of bacteria, such as Escherichia coli, but not in humans or other organisms. N-Succinyl5'-aminoimidazole-4-carboxamide ribose 5'-phosphate has been shown to be an inhibitor of antimicrobial agents such as penicillin G, erythromycin, and tetracycline. The mechanism for this inhibition is unclear, but it may involve hydrogen bonding interactions or structural changes that prevent binding</p>Formule :C13H19N4O12PDegré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :454.28 g/mol5'-Tosyl-2'-deoxycytidine
CAS :<p>5'-Tosyl-2'-deoxycytidine is a nucleoside with anticancer activity and is a novel derivative of cytidine. It has been shown to inhibit the proliferation of human cancer cells in culture. 5'-Tosyl-2'-deoxycytidine is also an antiviral agent that inhibits the synthesis of viral DNA by inhibiting the enzyme RNA polymerase. This product is synthetic, water soluble, and stable at pH 2.0 to 10.5, making it suitable for use in pharmaceutical formulations. The purity of this product is high and its chemical structure has been modified from cytidine to increase its stability against degradation by intracellular phosphatases.</p>Formule :C16H19N3O5SDegré de pureté :Min. 95%Masse moléculaire :365.41 g/mol2',3'-Dideoxycytidine 5'-monophosphate
CAS :<p>Dideoxycytidine 5'-monophosphate (DDCMP) is a molecule that inhibits HIV infection by inhibiting the synthesis of DNA. It binds to the dna template strand, preventing the addition of new nucleotides and thus blocking the progression of HIV infection. DDCMP has been shown to be potent in vitro and in vivo in clinical studies. In cell culture, DDCMP has been shown to inhibit DNA duplexes, leading to a decrease in lymphocytic leukemia cells activated by T-cell receptor stimulation. Structural biology studies have revealed that DDCMP inhibits HIV-1 reverse transcriptase through binding at the M2 subunit of the enzyme's active site.</p>Formule :C9H14N3O6PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :291.2 g/mol5'-o-(Dimethoxytrityl)-5-methyl-2'-o-methyluridine
CAS :<p>5'-O-(Dimethoxytrityl)-5-methyl-2'-O-methyluridine is a DNA building block that is used as a monophosphate and can be converted to diphosphate or modified with various protecting groups. This compound has been shown to have antiviral and anticancer properties, as well as being a novel nucleoside analog. 5'-O-(Dimethoxytrityl)-5-methyl-2'-O-methyluridine has the CAS number of 115173-73-4.</p>Formule :C32H34N2O8Degré de pureté :Min. 95%Masse moléculaire :574.6 g/molent-idoxuridine
CAS :<p>Ent-idoxuridine is a cytosolic DNA synthesis inhibitor that blocks the conversion of deoxycytidine to deoxyadenosine by inhibiting the enzyme deoxycytidine kinase. It is also an enantiomer of idoxuridine, which has the same mechanism of action. Ent-idoxuridine is not active against herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2). In contrast to idoxuridine, ent-idoxuridine is resistant to exonucleases and has been shown to be effective in treating immunodeficiency caused by HIV.</p>Formule :C9H11IN2O5Degré de pureté :Min. 95%Masse moléculaire :354.1 g/mol8-Methylthioadenosine
CAS :<p>8-Methylthioadenosine is a synthetic analogue of adenosine that has been used as a biochemical stimulator. It has been shown to inhibit uptake of fatty acids and phospholipids into cells, which may be due to the inhibition of cellular ATPase. 8-Methylthioadenosine can also be used as a precursor for other molecules, such as methylation of DNA or RNA. 8-Methylthioadenosine is synthesized from linolenic acid and phosphate in a reaction catalyzed by molecular oxygen. The synthesis is stimulated by light and heat and inhibited by cyanide. Magnetic resonance spectroscopy (NMR) was used to confirm that the molecule had the correct structure.</p>Degré de pureté :Min. 95%3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine
CAS :<p>3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine is a nucleoside phosphoramidite that is synthesized by the reaction of 3',5'-O-[Tetrakis(trimethylsiloxy)silyl]guanosine with tetrakis(1-methylethyl) siloxane. It is a novel monophosphate analogue of guanosine and has antiviral, anticancer and activator properties. 3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine is not toxic to cells and can be used in the treatment of cancer.</p>Formule :C22H39N5O6Si2Degré de pureté :Min. 95%Masse moléculaire :525.75 g/mol4'-Hydroxymethyl-4,5',8-trimethylpsoralen (hmt)
CAS :<p>4'-Hydroxymethyl-4,5',8-trimethylpsoralen (HMT) is an analog of psoralen that has been shown to have potent anti-tumor activity. HMT acts as an inhibitor of human tumor kinase and has been shown to induce apoptosis in cancer cells. This drug has also been found to enhance the effects of other cancer treatments, such as nintedanib. HMT has demonstrated potential for the treatment of diabetes by acting as an inhibitor of glucose uptake and metabolism in Chinese hamster ovary cells. Additionally, HMT has been found to have inhibitory effects on enzymes such as apomorphine, glimepiride, and vanillin. Overall, HMT holds great promise for the development of novel cancer therapies and diabetes treatments.</p>Formule :C15H14O4Degré de pureté :Min. 95%Masse moléculaire :258.27 g/mol5-(Furan-2-yl)-2'-deoxyuridine
CAS :<p>5-(Furan-2-yl)-2'-deoxyuridine is a novel anticancer drug that is an analog of thymine. 5-(Furan-2-yl)-2'-deoxyuridine inhibits DNA synthesis by inhibiting the formation of deoxythymidylate from uracil and 5-fluorouracil, which in turn prevents the incorporation of thymine into DNA. The drug has been shown to be active against human leukemia cells in culture and to inhibit viral replication in vitro. The drug also blocks RNA synthesis by inhibiting ribonucleotide reductase, preventing the production of nucleosides from nucleotides. 5-(Furan-2-yl)-2'-deoxyuridine has been modified to improve its solubility and stability. This compound is stable for up to 3 months when stored at 4 degrees Celsius and can be used as a starting material for other chemical compounds.</p>Formule :C13H14N2O6Degré de pureté :Min. 95%Masse moléculaire :294.26 g/mol4-(4-Fluorophenyl)pyrimidine-2-thiol
CAS :<p>4-(4-Fluorophenyl)pyrimidine-2-thiol is a monophosphate deoxyribonucleoside that has been modified to include an activator group. This modification allows for the phosphoramidite of 4-(4-Fluorophenyl)pyrimidine-2-thiol to be incorporated into DNA, which makes it a novel substance. The CAS number for 4-(4-Fluorophenyl)pyrimidine-2-thiol is 155957-43-0. 4-(4-Fluorophenyl)pyrimidine-2-thiol has shown anticancer activity in vitro and may have potential as a cancer chemotherapeutic agent.</p>Formule :C10H7FN2SDegré de pureté :Min. 95%Masse moléculaire :206.24 g/mol2'-Deoxyuridine
CAS :<p>Please enquire for more information about 2'-Deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C9H12N2O5Degré de pureté :Min. 98 Area-%Masse moléculaire :228.2 g/molRef: 3D-Q-200273
1kgÀ demander100gÀ demander250gÀ demander500gÀ demander2500gÀ demander-Unit-ggÀ demander8-Bromo-DA cep
CAS :<p>8-Bromo-2'-deoxyadenosine cep is a modified nucleoside that is used in the treatment of cancer. It has been shown to be effective in treating leukemia, lymphoma and myeloma. 8-Bromo-2'-deoxyadenosine cep inhibits the growth of cells by inhibiting DNA synthesis through inhibition of deoxynucleotide biosynthesis. This drug also has antiviral activity against herpes simplex virus type 1 (HSV1), herpes simplex virus type 2 (HSV2) and human immunodeficiency virus type 1 (HIV1). 8-Bromo-2'-deoxyadenosine cep is a synthetic nucleoside that is phosphoramidite that can be used to synthesize DNA or RNA.</p>Formule :C43H52BrN8O6PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :887.8 g/mol3'-Deoxy-N6-lauroyladenosine
CAS :<p>3'-Deoxy-N6-lauroyladenosine is a nucleoside analog that is used to treat cancer. It is a phosphoramidite compound and it has been shown to be highly active against cancer cells. 3'-Deoxy-N6-lauroyladenosine is an antiviral agent that inhibits viral DNA synthesis by competing with the natural substrate, deoxyribonucleosides, for incorporation into the growing DNA chain. It also prevents the replication of RNA viruses by inhibiting their transcription and translation processes. 3'-Deoxy-N6-lauroyladenosine also inhibits inflammation in the body and may act as a chemotherapeutic agent in other diseases such as diabetes, Alzheimer's disease, and Parkinson's disease.</p>Formule :C22H35N5O4Degré de pureté :Min. 95%Masse moléculaire :433.54 g/mol3'-O-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorouridine
<p>3'-O-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorouridine is a novel, activator, ribonucleosides, deoxyribonucleosides, diphosphate, phosphoramidites, modified nucleosides. It can be used as an anticancer and antiviral agent.</p>Formule :C32H31FN2O8Degré de pureté :Min. 95%Masse moléculaire :590.6 g/mol1-(2'-Deoxy-2'-fluoro-5'-O-trityl-b-L-arabinofuranosyl)-uracil
<p>1-(2'-Deoxy-2'-fluoro-5'-O-trityl-b-L-arabinofuranosyl)-uracil is a monophosphate nucleotide that is used in antiviral therapy. It inhibits viral DNA synthesis by inhibiting viral DNA polymerase and viral RNA transcription. The drug is currently in phase I clinical trials for the treatment of cancer and AIDS. 1-(2'-Deoxy-2'-fluoro-5'-O-trityl-b-L-arabinofuranosyl)-uracil is a novel compound that has not been described in the literature before. The drug was synthesized by modifying a natural nucleoside, uracil, with fluorine to produce an antiviral agent. This compound has shown anticancer effects in vitro and in vivo experiments as well as antiplasmodial activity against malaria.</p>Formule :C28H25FN2O5Degré de pureté :Min. 95%Masse moléculaire :488.51 g/molN6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine-3'-CE phosphoramidite
<p>N6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine-3'-CE phosphoramidite is a novel antiviral agent that exhibits high quality and high purity. It can be used to synthesize DNA, RNA, and other nucleosides. N6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine-3'-CE phosphoramidite is an activator of the DNA polymerase and an inhibitor of the viral polymerase. This compound has been shown to have anticancer properties in vitro and in vivo.</p>Formule :C31H40N7O7PDegré de pureté :Min. 95%Masse moléculaire :653.67 g/molN4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine 3'-CE phosphoramidite
<p>N4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine 3'-CE phosphoramidite is a novel, deoxyribonucleosides that has been synthesized with high purity, high quality, and high yield. It is an anticancer drug that inhibits the synthesis of ribonucleotides in DNA and RNA.</p>Degré de pureté :Min. 95%2'-Deoxy-2'-fluoroadenosine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS :<p>2'-Deoxy-2'-fluoroadenosine-5'-triphosphate lithium salt is an analog of ATP that has significant inhibitory effect on DNA polymerase. It inhibits the synthesis of RNA and protein by binding to the enzyme DNA gyrase. This drug is used in cell culture as a nucleotide analog to study how cells are affected by atp analogs. 2'-Deoxy-2'-fluoroadenosine-5'-triphosphate lithium salt is used at high concentrations in vitro, where it inhibits topoisomerases and prevents cell division.</p>Formule :C10H11FN5O12P3·4LiDegré de pureté :Min. 95%Masse moléculaire :532.9 g/molN4-Benzoyl-5'-O-DMT-(2'-O, 4'-C-methylene)-5-methyl-a-cytidine 3'-CE phosphoramidite
<p>N4-Benzoyl-5'-O-DMT-(2'-O, 4'-C-methylene)-5-methyl-a-cytidine 3'-CE phosphoramidite is a novel modified nucleoside that has antiviral and anticancer properties. It is synthesized by reacting the 3'-hydroxyl group of cytidine with 2,4,6-trimethoxybenzoyl chloride to form N4-(2',6'-dimethoxyphenyl)benzoylcytidine. This compound is then reacted with methylene bis(diethylamino)thiophene (2') and the 5' phosphoramidite of 5'-O-DMT-(2'-O, 4'-C-methylene)-5-methylcytidine. The product is an active synthetic nucleoside that can be used as a building block for other nucleosides or oligonucleotides.</p>Degré de pureté :Min. 95%2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine
CAS :<p>2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a novel nucleotide analog that exhibits anticancer activity. It has been shown to inhibit the growth of human leukemia cells and enhance the cytotoxic effect of doxorubicin. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a potent inhibitor of DNA synthesis with a high selectivity index for cancer cells. This agent inhibits DNA synthesis by competing with deoxyribonucleosides for incorporation into the growing DNA strand. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is an activator at the adenine phosphoribosyltransferase (APRT) enzyme and may also have an effect on ribonucleotide reductase (R</p>Formule :C26H26N6O9Degré de pureté :Min. 95%Masse moléculaire :566.5 g/mol4'-a-C-Methylguanosine
CAS :<p>4'-a-C-Methylguanosine is a nucleoside that is synthesized by the condensation of 4'-amino-2',3'-dideoxyadenosine and 1,2-ethanediol. This product is an activator that can be used to synthesize novel DNA analogues with various chemical modifications. It has shown antiviral and anticancer activity in vitro. 4'-a-C-Methylguanosine was also found to be more active than guanosine when it came to inhibiting viral replication in human cells.</p>Degré de pureté :Min. 95%2-(2-Furyl)-5-pyrimidinecarbaldehyde
CAS :<p>2-(2-Furyl)-5-pyrimidinecarbaldehyde (2FP) is a novel anticancer activator that belongs to the class of modified DNA. 2FP is a nucleoside analogue that inhibits the synthesis of DNA, RNA, and protein. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. This compound may be used as an antiviral agent against HIV and herpes virus infections. 2FP has high purity and quality, with CAS number 959240-19-8.</p>Formule :C9H6N2O2Degré de pureté :Min. 95%Masse moléculaire :174.16 g/molBenzoyl stavudine
CAS :<p>Benzoyl stavudine is a nucleoside that is used as an anti-HIV drug. It has been shown to be a prodrug of the active form, stavudine, by reductive elimination. Benzoyl stavudine has been shown to inhibit HIV replication by competitively binding to the viral reverse transcriptase enzyme and preventing the synthesis of RNA from DNA. This drug also inhibits ribonucleotide reductase, an enzyme that converts ribonucleotides into deoxyribonucleotides for DNA synthesis. This inhibition prevents the formation of new viral DNA and halts viral replication.</p>Formule :C17H16N2O5Degré de pureté :Min. 95%Masse moléculaire :328.32 g/mol8-Aminoguanosine
CAS :<p>8-Aminoguanosine is a synthetic purine nucleoside that inhibits DNA synthesis. It has been shown to inhibit the proliferation of HL-60 cells, which are a model for human monocytes and neutrophils. 8-Aminoguanosine has been shown to bind to the template strand of DNA and inhibit the incorporation of deoxyribonucleotide triphosphates into the newly synthesized strand. This binding prevents DNA replication by preventing access to the template strand of DNA. 8-Aminoguanosine inhibits cyclin D2, an enzyme required for cell division, at concentrations as low as 0.1 mM, and it also inhibits microtubule assembly. 8-Aminoguanosine has shown in vitro activity against various tumor cell lines including Molt-4 and MCF7 cells, and in vivo activity in a mouse model against C3H/HeJ mice transplanted with Lewis lung carcinoma cells.</p>Formule :C10H14N6O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :298.26 g/mol5-Aminoallyluridine 5'-triphosphate sodium salt - 100mM aqueous solution
CAS :<p>5-Aminoallyluridine 5'-triphosphate sodium salt is a modified nucleoside that has antiviral and anticancer activity. It is a prodrug of 5-aminoallyluridine and is activated by deoxyribonucleotide ribonucleotides in the cell. This drug also can be used as an activator for other drugs, such as cytosine arabinoside, which are inactive or less active when administered alone.</p>Formule :C12H20N3O15P3·xNaDegré de pureté :Min. 95%Masse moléculaire :539.22 g/mol6-Azathymidine ce-phosphoramidite
CAS :<p>Please enquire for more information about 6-Azathymidine ce-phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C39H48N5O8PDegré de pureté :Min. 95%Masse moléculaire :745.8 g/molUridine 5'-triphosphate
CAS :<p>P2Y receptor agonist; precursor in RNA biosynthesis</p>Formule :C9H15N2O15P3Degré de pureté :Min. 95%Masse moléculaire :484.14 g/mol2,4,5,6-Tetraaminopyrimidine 2HCl
CAS :<p>2,4,5,6-Tetraaminopyrimidine 2HCl is a chemical compound that belongs to the group of pyrimidines. It is a colorless solid with a melting point of 178.2°C and a boiling point of 339.8°C. This compound can be obtained by reacting 2,4,5-trichloropyrimidine with potassium cyanide in acetic acid solution or by heating 2,4-diaminopyrimidine with ammonium chloride and sodium nitrate in water.<br>In the liquid chromatography process this compound is used as an analytical reagent for determining the purity and identity of organic compounds by measuring their retention time on the column.</p>Degré de pureté :Min. 95%2',3'-Dideoxy-2',3'-didehydrocytidine
CAS :<p>2',3'-Dideoxy-2',3'-didehydrocytidine (ddC) is a nucleoside analog that is used in the treatment of hepatitis B and C. This drug inhibits the reverse transcriptase enzyme and has cytostatic effects on viruses, for example, by preventing cell division. 2',3'-Dideoxy-2',3'-didehydrocytidine also inhibits viral replication by acting as an antigen and inducing antibody production. This drug binds to a variety of enzymes, including preparations of cellular enzymes, human immunodeficiency virus type 1 (HIV-1), and reverse transcriptase. The effective dose of ddC is 300 mg/day given orally.</p>Formule :C9H11N3O3Degré de pureté :Min. 95%Masse moléculaire :209.2 g/mol1-(2',3',5'-Tri-O-acetyl-b-D-arabinofuranosyl)uracil
<p>1-(2',3',5'-Tri-O-acetyl-b-D-arabinofuranosyl)uracil is a novel nucleoside analog with antiviral and anticancer activities. It is a modified nucleoside that is synthesized from 2',3',5'-triacetyl b-D-arabinofuranosyl uracil. The synthesis of this compound involves the use of acetylation, which produces a monophosphate form of the nucleoside. This product has been shown to be an activator in the synthesis of DNA and RNA.</p>Degré de pureté :Min. 95%Lamivudine 5'-monophosphate ammonium salt
CAS :<p>Lamivudine 5'-monophosphate ammonium salt is a novel antiviral agent that inhibits the viral polymerase by competing with natural dNTPs. It has been shown to be effective against Hepatitis B virus (HBV) and human immunodeficiency virus type 1 (HIV-1). Lamivudine 5'-monophosphate ammonium salt is a synthetic nucleoside that is phosphorylated to form its active form, lamivudine 5'-triphosphate ammonium salt. This drug has been shown to inhibit tumor growth in vivo and in vitro.</p>Formule :C8H15N4O6PSDegré de pureté :Min. 95%Masse moléculaire :326.27 g/mol2',3',5'-Tri-O-acetylnebularine
CAS :<p>2',3',5'-Tri-O-acetylnebularine is a modified nucleoside that is synthesized from nebulareine. It has been shown to inhibit the growth of cancer cells, as well as HIV and influenza virus. This drug also has antiviral effects against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2). 2',3',5'-Tri-O-acetylnebularine inhibits viral replication by inhibiting DNA synthesis and RNA transcription, which prevents the production of proteins needed for cell multiplication.</p>Formule :C16H18N4O7Degré de pureté :Min. 95%Masse moléculaire :378.34 g/mol5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine
CAS :<p>5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine is a nucleoside, a type of chemical compound containing both a sugar (deoxyribose) and an organic molecule (a base). It is an antiviral agent that inhibits the production of viral DNA by inhibiting the enzyme DNA polymerase. 5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine is also an anticancer agent that can inhibit the production of cancer cells in vitro and in vivo. This product is a novel monophosphate nucleotide analog with high purity and CAS number 1422361-25-8.</p>Degré de pureté :Min. 95%5-Bromo-2',3'-dideoxyuridine
CAS :<p>5-Bromo-2',3'-dideoxyuridine is a nucleoside analogue that is used as a chemotherapeutic drug against various types of cancer. It has been shown to have anti-tumour activity by interfering with the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). 5-Bromo-2',3'-dideoxyuridine binds to the sugar ring in DNA and inhibits the enzyme DNA polymerase from synthesizing DNA. This drug also stabilizes conformations of the molecule, which are responsible for its pharmacological effects.<br>5-Bromo-2',3'-dideoxyuridine can be found in two different crystal structures, monoclinic and tetragonal. The monoclinic form is stabilized by hydrogen bonds between the puckers in the sugar ring and hydrogen bonds to neighboring molecules. This form is more soluble than the tetragonal form,</p>Degré de pureté :Min. 95%1-(5-o-(Dimethoxytrityl)-β-D-2-deoxyribofuranosyl)-3-nitropyrrole
CAS :<p>1-(5-O-(dimethoxytrityl)-β-D-2-deoxyribofuranosyl)-3-nitropyrrole is a novel nucleoside phosphoramidite that has been modified to include an oxazole moiety. It is an antiviral and anticancer drug that inhibits the replication of DNA by binding to the enzyme DNA polymerase. 1-(5-O-(dimethoxytrityl)-β-D-2-deoxyribofuranosyl)-3-nitropyrrole is also a substrate for monophosphate, diphosphate, and triphosphate nucleotide kinases, which are enzymes that catalyze the phosphorylation of 5'-monophosphates. This nucleoside phosphoramidite can be used in the synthesis of oligonucleotides and modified oligonucleotides.</p>Formule :C30H30N2O7Degré de pureté :Min. 95%Masse moléculaire :530.6 g/mol8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite
<p>8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel nucleoside that is synthesized from 8-bromo-2'-deoxyadenosine and N,N,-diisopropylethylamine. It has been shown to have anticancer, antiviral, and antiinflammatory activities. This compound is also used as an activator in the synthesis of DNA and RNA. The purity of this product exceeds 99% and it has been modified for use with automated synthesizers.</p>Formule :C43H52BrN8O6PDegré de pureté :Min. 95%Masse moléculaire :887.82 g/mol3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite
CAS :<p>3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite is a nucleotide analogue that is used in the synthesis of DNA. It is a modified nucleoside that contains an amino group at the 5' position of the pentose sugar and a methyl group at the 2' position. 3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite inhibits viral replication and has shown anticancer activity. It also possesses antiviral activity against Herpes simplex virus types 1 and 2, cytomegalovirus, varicella zoster virus, Epstein Barr virus, influenza A virus type A/PR/8/34 (H1N1), and human immunodeficiency virus type 1 (HIV).</p>Formule :C40H49N4O8PDegré de pureté :Min. 95%Masse moléculaire :744.81 g/molBiotin-18-cytidine-5'-triphosphate triethylammonium salt - 5mM aqeous solution
<p>Biotin-18-cytidine-5'-triphosphate triethylammonium salt - 5mM aqeous solution is an activator of DNA synthesis. It is a cytidine nucleoside with a biotin label at the 5' position that is used as a substrate in DNA synthesis reactions. Biotin-18-cytidine-5'-triphosphate triethylammonium salt - 5mM aqeous solution is also used to make phosphoramidites, which are building blocks for oligonucleotide synthesis. This product can be used in anticancer and antiviral research.</p>Formule :C34H55N8O18P3SDegré de pureté :Min. 95%Masse moléculaire :988.83 g/molN6-Formyl adenosine
CAS :<p>N6-Formyl adenosine is an endogenous nucleotide that is dynamically modified in the human body. N6-Formyl adenosine is a reactive modification of adenosine and has been shown to be present in DNA, RNA, and proteins. It is also found in human cells and tissues, where it can be demethylated by enzymes such as DNA methyltransferase. This modification may have implications for research into the nature of messenger RNA (mRNA), which plays a crucial role in protein synthesis. N6-Formyl adenosine has been used to distinguish between mature and immature mRNA molecules by fluorescence analysis.</p>Formule :C11H13N5O5Degré de pureté :Min. 97 Area-%Masse moléculaire :295.25 g/mol

