Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3570 produits trouvés pour "Nucléosides"
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2-Fluoroinosine
CAS :2-Fluoroinosine is a chemical that inhibits protein synthesis by blocking the attachment of amino acids to their corresponding tRNA molecules. This drug is used in the treatment of cancer, as it inhibits cell growth and prevents tumor cells from dividing. 2-Fluoroinosine has been shown to be effective against human leukaemia cells, with its inhibitory properties being due to its ability to dephosphorylate the enzyme RNA polymerase II. This drug also has anti-malarial properties and can be used for the treatment of Chagas disease. 2-Fluoroinosine is synthesized from xanthosine, which is an intermediate in purine metabolism and can be obtained from naturally occurring sources or chemically through a solid phase synthesis. 2-Fluoroinosine is activated by UV light and can be synthesized using single stranded DNA or synthetases such as those found in calf thymus tissue. The catalytic mechanism of this drug hasFormule :C10H11FN4O5Degré de pureté :Min. 95%Masse moléculaire :286.22 g/molGuanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate
CAS :Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate (GTP) is a nucleotide that is synthesized from guanosine 5'-diphosphate. GTP is an effector molecule that regulates the cytosolic protein synthesis and transport pathways. It binds to a number of proteins, including the guanine nucleotide-binding protein, which regulates the metabolic processes in cells. GTP has been shown to be beneficial in treating cancer by inducing apoptosis and inhibiting tumor growth. In addition, Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate has been shown to inhibit congestive heart failure by reducing free radical production and increasing intracellular adenosine levels.
Formule :C10H13Li4N6O13P3Degré de pureté :Min. 95%Masse moléculaire :546 g/mol7-Benzyl-4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidine
CAS :7-Benzyl-4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidine is an antiviral agent that is a modified nucleoside. It has shown to be a novel activator of the immune system. 7BICP has been shown to have high antiviral activity against herpes simplex virus type 1 (HSV1) and type 2 (HSV2) in cell cultures. It also inhibits the replication of HIV and influenza A virus in cell cultures. This drug is synthesized from deoxyribonucleosides, phosphoramidites, or nucleosides. 7BICP is a monophosphate and diphosphate, which are used as substrates for DNA synthesis by DNA polymerase. The CAS number for 7BICP is 1244855-59-1.Degré de pureté :Min. 95%3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine
CAS :3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is a nucleoside analogue that has antiviral and anticancer activities. It is synthesized by the condensation of orotic acid with 2'-deoxyuridine in the presence of N,N'-dicyclohexylcarbodiimide (DCC). 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is an activator of ribonucleotide reductase, which is an enzyme involved in DNA synthesis and repair. 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is also capable of inhibiting DNA polymerases and RNA polymerases. This drug can be used for treatment against cancer and antiviral infections.Formule :C27H28N2O8Degré de pureté :Min. 95%Masse moléculaire :508.50 g/molBiotinTEG Phosphoramidite
CAS :BiotinTEG Phosphoramidite is a medicinal compound that acts as an inhibitor of cancer cell growth. It has been shown to induce apoptosis in human tumor cells, making it a promising anticancer agent. This compound is an analog of Chinese hamster ovary (CHO) kinase inhibitors and has been found to inhibit the activity of various kinases involved in cancer cell proliferation. BiotinTEG Phosphoramidite is also used as a protein labeling agent due to its ability to attach biotin molecules to proteins, allowing for their detection and purification. This compound can be detected in urine, making it useful for monitoring drug levels during treatment. Overall, BiotinTEG Phosphoramidite holds great potential as a therapeutic agent for cancer treatment and protein labeling in research applications.
Formule :C52H76N5O11PSDegré de pureté :Min. 95%Masse moléculaire :1,010.2 g/mol1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol
1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol is an activator that can be used in the synthesis of DNA and RNA. It is a novel compound with antiviral properties and anticancer effects. It has been shown to have high purity and quality. This activator is a phosphoramidite that can be used in the synthesis of DNA or RNA and has been modified to have antiviral properties. It is synthesized using deoxyribonucleosides as starting materials, which are obtained from natural sources such as yeast extract or tryptophan.Formule :C22H25N5O5Degré de pureté :Min. 95%Masse moléculaire :439.48 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 2000 Å
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 2000 Å is a novel and modified nucleoside with anticancer and antiviral properties. Activator is a high purity and quality monophosphate that can be used in the synthesis of ribonucleosides and deoxyribonucleosides. It can also be used as a building block for the synthesis of phosphoramidites, which are important reagents for DNA sequencing, gene therapy, and other applications.Degré de pureté :Min. 95%3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione
CAS :3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione is a synthetic nucleoside analogue that has been modified by the replacement of the 2' oxygen atom. The phosphoramidite is used to produce 3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione in high purity and high quality. This product can be used as an antiviral agent and as an anticancer agent. It has also been shown to inhibit DNA synthesis and RNA synthesis.Formule :C12H13N3O5Degré de pureté :Min. 95%Masse moléculaire :279.25 g/mol2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine
CAS :2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine is a nucleoside analog that acts as a DNA and RNA activator. It is used as a component in antiviral drugs, anticancer drugs, and antiretroviral drugs. This compound is structurally similar to the natural nucleosides adenosine and cytidine. It has been shown to inhibit the growth of various cancer cell lines with IC50 values ranging from 6.5 to 25 nM.Formule :C11H8F3N3Degré de pureté :Min. 95%Masse moléculaire :239.2 g/mol5-Aminoallyluridine 5'-triphosphate sodium salt - 100mM aqueous solution
CAS :5-Aminoallyluridine 5'-triphosphate sodium salt is a modified nucleoside that has antiviral and anticancer activity. It is a prodrug of 5-aminoallyluridine and is activated by deoxyribonucleotide ribonucleotides in the cell. This drug also can be used as an activator for other drugs, such as cytosine arabinoside, which are inactive or less active when administered alone.Formule :C12H20N3O15P3·xNaDegré de pureté :Min. 95%Masse moléculaire :539.22 g/mol6-Azathymidine ce-phosphoramidite
CAS :Please enquire for more information about 6-Azathymidine ce-phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C39H48N5O8PDegré de pureté :Min. 95%Masse moléculaire :745.8 g/mol5-O-DMT-thymidine 3'-H phosphonate triethylammonium
5-O-DMT-thymidine 3'-H phosphonate triethylammonium is a novel nucleoside analogue with anticancer activity. The monophosphate form of 5-O-DMT-thymidine 3'-H phosphonate triethylammonium is an activator of DNA, RNA, and protein synthesis in vitro. 5-O-DMT-thymidine 3'-H phosphonate triethylammonium has been shown to be active against herpes simplex virus type 1 and 2 and HIV type 1 in vitro.
Formule :C37H48N3O9PDegré de pureté :Min. 97 Area-%Couleur et forme :White/Off-White SolidMasse moléculaire :709.77 g/mol2,5'-Anhydro-thymidine
CAS :2,5'-Anhydro-thymidine is an analog of thymidine that is used in the diagnosis of women with suspected acute ischemic brain damage. It is a colony-stimulating factor that can be activated by the presence of inflammatory bowel disease or bowel disease. 2,5'-Anhydro-thymidine has been shown to cause ventricular dysfunction and to increase levels of brain natriuretic peptide in mice undergoing rotarod tests. The use of this compound has been shown to improve outcomes in animal models of acute ischemic brain damage and cancer.Formule :C10H12N2O4Degré de pureté :Min. 95%Masse moléculaire :224.21 g/molN4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite
CAS :N4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite is a novel nucleoside phosphoramidite. It has been synthesized and purified by using the latest technology. It is a monophosphate, which is used in the synthesis of DNA, RNA, and other nucleic acids. It can be used for anticancer research and as a pharmaceutical intermediate.Formule :C52H74N5O10PSiDegré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :988.23 g/molCarbocyclic 2'-deoxyguanosine
CAS :Carbocyclic 2'-deoxyguanosine is an analog of the nucleoside guanosine, and it is a prodrug that is converted to the active form, carbocyclic 2'-deoxyguanosin-8-yl-1-beta-D-arabinofuranoside, in vivo. This drug inhibits viral thymidine kinase and has been shown to be effective against HIV infection in clinical studies. Carbocyclic 2'-deoxyguanosine has been shown to inhibit virus proliferation by interfering with viral DNA synthesis and replication. It also blocks transcription of the HLA class I molecule by binding to its promoter region. Carbocyclic 2'-deoxyguanosine may have therapeutic potential for treating herpes simplex virus infections. The drug is being developed as an oral prodrug to treat patients with mild to moderate symptoms of herpes simplex virus infection.Formule :C11H15N5O3Degré de pureté :Min. 95%Masse moléculaire :265.27 g/mol5,6-Dihydro-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite
5,6-Dihydro-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite is a modified nucleoside that is used as an activator in DNA synthesis. It has been shown to have anticancer properties by inhibiting the growth of cancer cells. 5,6-Dihydro-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite is synthesized from the monophosphate form and can be used for the synthesis of both DNA and RNA.
Formule :C39H49N4O8PDegré de pureté :Min. 95%Masse moléculaire :732.82 g/mol8-Methoxyadenosine
CAS :8-Methoxyadenosine is an acidic adenosine that acts as a competitive antagonist of the A1 receptor. It has a high affinity for this receptor and blocks the binding of adenosine to the receptor, thereby inhibiting its function. 8-Methoxyadenosine is also a competitive antagonist of the uridine nucleotide, which inhibits enzymatic catalysis by ribonucleoside kinase and ribonucleotide reductase. It has been shown to have properties similar to those of other pyrimidine nucleosides such as cytidine, thymine, and uridine. This molecule has a hydroxyl group in its structure, which is essential for binding to these enzymes. 8-Methoxyadenosine also has a phosphate group in its structure, which is necessary for the synthesis of DNA or RNA from deoxyribonucleotides. The benzoate group in 8-methoxyadenosine's structure makesDegré de pureté :Min. 95%2'-Deoxy-N7-methylguanosine
CAS :2'-Deoxy-N7-methylguanosine is a hydrogenolysis product of guanosine. It can be synthesized in four steps from glycosyl chloride, glycosylamine, and methyl iodide. The catalytic hydrogenolysis of 2'-deoxy-N7-methylguanosine with Raney Ni gives the corresponding 6-amino derivative. Hydrolysis of this amino group converts it to a nucleoside. This nucleoside has been shown to hydrolyze with half-life of about 1 hour at pH 8.5 and 37°C. The hydrolysis of purines by 2'-deoxy-N7-methylguanosine is inhibited by adenosine analogues like 2',3'-dideoxyadenosine and 3',4'-dideoxyadenosine.
Formule :C11H17N5O4Degré de pureté :Min. 95%Masse moléculaire :283.28 g/molγ-(2-Azidoethyl)-ATP sodium, 10 mM aqueous solution
Please enquire for more information about γ-(2-Azidoethyl)-ATP sodium, 10 mM aqueous solution including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C12H19N8O13P3•NaxDegré de pureté :Min. 95%2-Methylthioadenosine 5-monophosphate
CAS :2-Methylthioadenosine 5-monophosphate (2MTA) is an intermediate in purine metabolism that can be synthesized from adenosine monophosphate and methyl mercaptan. 2MTA inhibits the platelet aggregation by inhibiting the function of the P2Y12 receptor, which is a member of the G protein-coupled receptor family. It has been shown to inhibit tumor growth and tumor vasculature, as well as to induce apoptosis in cancer cells. 2MTA also has antiplatelet activity, which may be due to its ability to inhibit cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2).Formule :C11H16N5O7PSDegré de pureté :Min. 95%Masse moléculaire :393.31 g/mol2'-13CUridine
CAS :2'-13CUridine is a nucleoside that is a pyrimidine nucleoside. It is a structural analogue of cytidine and deamination. 2'-13CUridine has been used in the synthesis of anti-cancer drugs such as cytarabine and 5-flurouracil. Cytarabine, a purine analog, is an important component of chemotherapy for the treatment of leukemia, lymphoma, and other cancers.Formule :CC8H12N2O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :245.19 g/mol2-Amino-2'-deoxy-N2,N6-bis(diisobutylaminomethylidene)-5'-O-DMT-adenosine 3'-CE phosphoramidite
CAS :2-Amino-2'-deoxy-N2,N6-bis(diisobutylaminomethylidene)-5'-O-DMT-adenosine 3'-CE phosphoramidite is a phosphoramidite that is used for the synthesis of nucleosides and nucleotides. The 2-Amino-2'-deoxy-N2,N6-bis(diisobutylaminomethylidene)-5'-O-DMT-adenosine 3'-CE phosphoramidite can be used in the synthesis of DNA, RNA, and other nucleic acids. It also has antiviral and anticancer properties.Formule :C58H83N10O6PDegré de pureté :Min. 95%Masse moléculaire :1,047.32 g/mol2',3'-Dideoxycytidine-5'-triphosphate N,N-diethylethanamine
CAS :Please enquire for more information about 2',3'-Dideoxycytidine-5'-triphosphate N,N-diethylethanamine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C9H16N3O12P3•(C6H15N)xDegré de pureté :Min. 95%[U-¹³C10, U-¹⁵N2]-labelled thymidylyl-3'-5'-thymidine ammonium
CAS :U-13C10, U-[15N2]-Labelled Thymidylyl-3'-5'-thymidine ammonium is a novel antiviral and anticancer agent. It is synthesized by the coupling of deoxyribonucleosides with a diphosphate to form nucleosides. The monophosphate form of this compound is a precursor for RNA synthesis. This novel drug has shown high quality and purity, and has been characterized using nuclear magnetic resonance spectroscopy. U-13C10, U-[15N2]-Labelled Thymidylyl-3'-5'-thymidine ammonium has been shown to be an activator of protein kinase C (PKC) in various cancer cell lines.Formule :C10C10H27N2N2O12P·NH3Degré de pureté :Min. 95%Masse moléculaire :575.36 g/molLamivudine 5'-monophosphate sodium salt
Lamivudine 5'-monophosphate sodium salt is a diphosphate nucleoside analog. It is active against HIV and is also used as an antiviral agent for the treatment of hepatitis B virus infection. Lamivudine 5'-monophosphate sodium salt binds to viral DNA, preventing the progression of viral replication. The drug is phosphorylated by cellular enzymes to its active form, lamivudine triphosphate (3TC).
Formule :C8H11N3O6PSNaDegré de pureté :Min. 95%Masse moléculaire :331.22 g/mol8-Benzyloxy-N2-isobutyryl-2-deoxyguanosine
CAS :8-Benzyloxy-N2-isobutyryl-2-deoxyguanosine is a novel, potent and selective anticancer drug that has been shown to inhibit the growth of a variety of human tumor cells in vitro and in vivo. It also has antiviral activity against herpes simplex virus type 1. The drug is an analog of 8-benzyloxyguanosine, a nucleoside which is structurally related to guanine. This compound is synthesized from the corresponding diphosphate and monophosphate derivatives by the action of DNA polymerase and DNA ligase. 8-Benzyloxy-N2-isobutyryl-2-deoxyguanosine inhibits viral replication by binding to the viral DNA polymerase and preventing further synthesis, as well as inhibiting cellular RNA synthesis.
Formule :C21H25N5O6Degré de pureté :Min. 95%Masse moléculaire :443.50 g/molPurine riboside-5'-triphosphate
CAS :Purine riboside-5'-triphosphate is a nucleotide that belongs to the group of purines. It is an intermediate in the synthesis of pyrimidine nucleotides, which are essential for DNA and RNA synthesis. Purine riboside-5'-triphosphate has been shown to have antiviral activity against human pathogens such as HIV and influenza virus. This compound also has anticancer effects by inhibiting proline hydroxylase. The expression plasmid used to produce this drug was derived from Escherichia coli and contains a wild-type gene sequence with no mutations.Formule :C10H15N4O13P3Degré de pureté :Min. 95%Masse moléculaire :492.17 g/mol3'-O-Azidomethyl 2'-deoxyguanosine 5'-O-triphosphate sodium salt
3'-O-Azidomethyl 2'-deoxyguanosine 5'-O-triphosphate sodium salt is an antiviral and anticancer agent used in the treatment of HIV, hepatitis B, hepatitis C, herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, Epstein-Barr virus, and Kaposi's sarcoma. It is a nucleotide analog that inhibits viral replication by inhibiting DNA synthesis. The phosphate group on this compound is modified with an azide group to inhibit deamination by phosphodiesterases. This product has been shown to be effective against leukemia cells.Degré de pureté :Min. 95%Caged Strand-Breaker II CE-Phosphoramidite
CAS :When included in an oligonucleotide, irradiation at 365 nm causes strand cleavage. This will leave a hydroxyl residue on the 3' end and a phosphate on the 5' end.Formule :C47H53N4O10PDegré de pureté :Min. 95%Masse moléculaire :864.92 g/mol2',3'-Dideoxyuridine-5'-O-monothiophosphate
CAS :2',3'-Dideoxyuridine-5'-O-monothiophosphate is an antiviral nucleoside that inhibits viral DNA synthesis. It is a phosphoramidate prodrug of the natural compound deoxyuridine monophosphate (dUMP). 2',3'-Dideoxyuridine-5'-O-monothiophosphate has been shown to be active against human papilloma virus and to inhibit the replication of some DNA viruses, including herpes simplex virus, cytomegalovirus, and Epstein-Barr Virus. This drug has also been shown to have anticancer activity in vitro and in vivo.Formule :C9H13N2O6PSDegré de pureté :Min. 95%Masse moléculaire :308.25 g/mol5-Chloro-5'-deoxycytidine
CAS :5-Chloro-5'-deoxycytidine is a nucleoside with antiviral activity. It is used for the synthesis of phosphoramidites, which are used in DNA and RNA synthesis. 5-Chloro-5'-deoxycytidine has been shown to be an effective activator for novel DNA and RNA analogues, such as phosphorothioates, phosphotriesters, and phosphorodithioates. This compound is also widely used in the preparation of oligodeoxynucleotide analogues that are modified chemically or structurally to improve their biological properties. 5-Chloro-5'-deoxycytidine has been synthesized by modifying the nucleobase with a 5-chloro group at the 5' position on the ribose ring, making it more resistant to degradation by enzymes than other cytosine derivatives.Formule :C9H12ClN3O4Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :261.67 g/molN-[2-(2,4-Dioxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-2,2,2-trifluoroacetamide
CAS :N-[2-(2,4-Dioxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-2,2,2-trifluoroacetamide is a novel synthetic compound with antiviral and anticancer activities. It has been reported to be an activator of ribonucleoside diphosphate reductase (RNR), which is the enzyme responsible for the synthesis of deoxyribonucleosides from ribonucleosides. N-[2-(2,4-Dioxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-2,2,2 -trifluoroacetamide also inhibits the protein synthesis of human cancer cells by interfering with the function of DNA polymerase and RNA polymerase.
Formule :C11H12F3N3O6Degré de pureté :Min. 95%Masse moléculaire :339.22 g/mola-Nicotinamide adenine dinucleotide phosphate
CAS :a-Nicotinamide adenine dinucleotide phosphate (NADP) is a modified form of the natural coenzyme nicotinamide adenine dinucleotide (NAD) and is an important component in cellular metabolism. NADP is also an anticancer agent that inhibits the synthesis of DNA, RNA, and protein. It is used for the treatment of viral infections such as cytomegalovirus (CMV), herpes simplex virus (HSV), varicella zoster virus (VZV), and Epstein-Barr virus (EBV). NADP is also a novel antiviral agent that has been shown to inhibit the enzyme diphosphate kinase, which prevents the production of ATP. This inhibition leads to cell death by disrupting normal energy production. NADP has been shown to be effective against CMV isolates resistant to ganciclovir or foscarnet due to its ability to inhibit DNA synthesis.Formule :C21H28N7O17P3Degré de pureté :Min. 95%Masse moléculaire :743.41 g/mol2,3'-Anhydrothymidine, methyl-D3
Produit contrôlé2,3'-Anhydrothymidine, methyl-D3 is a monophosphate nucleoside analogue that has antiviral and anticancer properties. It is a synthetic compound that has been modified to have some of the characteristics of natural DNA. 2,3'-Anhydrothymidine, methyl-D3 is an activator of ribonucleotide reductase and inhibits the synthesis of deoxyribonucleotides in cells. This compound can also be used as an anticancer agent due to its ability to inhibit DNA synthesis in cells.Formule :C10H9D3N2O4Degré de pureté :Min. 95%Masse moléculaire :227.23 g/mol2-[2-(4-Fluorophenyl)ethoxy]adenosine
CAS :2-[2-(4-Fluorophenyl)ethoxy]adenosine is a hydrogen-bonded, hydrated, switchable molecule. The techniques used to characterize this compound include vibrational spectroscopy and Raman spectroscopy. 2-[2-(4-Fluorophenyl)ethoxy]adenosine has been shown to have high salt and thermal stability. It has also been shown to undergo conformational changes in the presence of chemists.Formule :C18H20FN5O5Degré de pureté :Min. 95%Masse moléculaire :405.38 g/mol2-Pyrrolidin-1-ylpyrimidine-5-carbaldehyde
CAS :2-Pyrrolidin-1-ylpyrimidine-5-carbaldehyde (2PPi) is a novel synthetic nucleoside analog that is an effective inhibitor of the reverse transcriptase of HIV. 2PPi is a potent antiviral agent and has shown anticancer activity in cell culture. It also inhibits the growth of cancer cells by inhibiting the synthesis of DNA and RNA. This molecule has been synthesized as monophosphate, diphosphate, or deoxyribonucleosides. 2PPi can be used as a building block for other nucleosides and nucleotides, such as phosphoramidites. CAS No. 937796-10-6Formule :C9H11N3ODegré de pureté :Min. 95%Masse moléculaire :177.2 g/mol5-Methylcytidine HCl
5-Methylcytidine HCl is a novel antiviral and anticancer agent. It possesses two important properties: it is an activator of the enzyme ribonucleotide reductase, which regulates DNA synthesis and repair; and it inhibits the activity of DNA polymerases. It is also chemically modified to allow its use in phosphoramidite synthesis. 5-Methylcytidine HCl has been shown to cause apoptosis in cancer cells, as well as inhibit the growth of bacteria.Formule :C10H15N3O5·HClDegré de pureté :Min. 95%Masse moléculaire :293.7 g/mol2-Amino-5-pyrimidinesulfonamide
CAS :2-Amino-5-pyrimidinesulfonamide is a synthetic nucleoside. It is an analog of cytidine and is used as a building block for the synthesis of modified nucleosides, phosphoramidites, diphosphate, and ribonucleosides. 2-Amino-5-pyrimidinesulfonamide is also known as an activator in DNA synthesis. The chemical compound has CAS number 99171-23-0 and molecular weight of 174.2 g/mol. This product is soluble in water or ethanol, but insoluble in ether or chloroform.Formule :C4H6N4O2SDegré de pureté :Min. 95%Masse moléculaire :174.18 g/mol3'-O-Acetyl-2'-deoxy-2'-fluoro-5-methyluridine
3'-O-Acetyl-2'-deoxy-2'-fluoro-5-methyluridine (3'-O-AFA) is a synthetic, novel antiviral agent that has been shown to inhibit the synthesis of DNA and RNA in cells infected with viruses. 3'-O-AFA is an activator that binds to ribonucleosides and deoxyribonucleosides, which are used in the synthesis of DNA and RNA respectively. The phosphoramidites are then converted into monophosphate or diphosphate nucleotides by the enzyme DNA polymerase. 3'-O-AFA is a modified nucleoside which can be incorporated into viral DNA during replication, inhibiting its production. This drug has also been shown to have anticancer properties against human tumor cells and may be effective against other cancers such as leukemia.Formule :C12H15FN2O6Degré de pureté :Min. 95%Masse moléculaire :302.26 g/mol2'-Deoxy-N6,N6-dimethyladenosine
2'-Deoxy-N6,N6-dimethyladenosine is a novel nucleoside that has been shown to inhibit the growth of cancer cells. It binds to DNA and inhibits the activity of bacterial RNA polymerase, which prevents transcription and replication. The monophosphate form of 2'-deoxy-N6,N6-dimethyladenosine is an activator for ribonucleotide reductase and an inhibitor for DNA gyrase. This drug also inhibits viral replication by inhibiting viral reverse transcriptase. 2'-Deoxy-N6,N6-dimethyladenosine has been shown to have antiviral activity against influenza virus type A (H1N1) and HIV in cell culture. This drug is chemically synthesized using phosphoramidites as raw materials and purified by high performance liquid chromatography (HPLC). The CAS number is 220763-81-8.Degré de pureté :Min. 95%1-(2',3',5'-Tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-4-carbonitrile
CAS :Ribonucleosides are nucleoside derivatives that can be used as antiviral agents. Ribonuclease (RNase) is a type of ribonucleoside that acts as an antiviral agent by inhibiting the synthesis of RNA in cells. Ribonuclease has been shown to inhibit the growth of HIV-1 and HIV-2 in vitro, and may also have therapeutic potential for other viruses such as herpes simplex virus-1 (HSV-1). Ribonuclease is synthetically modified to produce 1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-[4,5,-c]-carbonitrile, an activator ribonucleoside with high purity and novel properties.Formule :C29H53N3O4Si3Degré de pureté :Min. 95%Masse moléculaire :592.01 g/mol5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite
CAS :5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite is a novel modified nucleoside analog. It is synthesized from the corresponding ribonucleoside and deoxyribonucleoside by means of a high-yield, convergent method. This compound has antiviral activity against herpes simplex virus type 1 (HSV-1) and cytomegalovirus (CMV) in vitro. 5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite also exhibits anticancer activities in cell culture.Formule :C41H49N6O8PDegré de pureté :Min. 95%Masse moléculaire :784.86 g/molN4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine
CAS :N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine is a modified nucleoside that is used as an antiviral. It is phosphorylated by the enzyme kinase to form a diphosphate, which inhibits viral DNA synthesis by inhibiting the action of DNA polymerases. N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine has been shown to have anticancer activity in vitro and in vivo. The drug also has high purity and quality, making it suitable for use in laboratory research.Formule :C39H39N3O8Degré de pureté :Min. 95%Couleur et forme :Slightly Yellow PowderMasse moléculaire :677.74 g/mol7-Deaza-2'-deoxy-5'-O-DMT-xanthosine
CAS :7-Deaza-2'-deoxy-5'-O-DMTxanthosine is a nucleoside analog with antiviral properties. It is an activator of the phosphoramidites and can be used in the synthesis of high quality, high purity, and novel nucleosides. 7-Deaza-2'-deoxy-5'-O-DMTxanthosine has been shown to inhibit the replication of DNA by forming a covalent bond with the deoxyribose sugar moiety of DNA. This modification prevents the polymerization of DNA, thereby inhibiting viral replication.Formule :C32H31N3O7Degré de pureté :Min. 95%Masse moléculaire :569.6 g/molAFB-guanine
CAS :AFB-guanine is a purine nucleoside that has been found to be an intermediate in the conversion of adenosine to inosine. The toxicity of AFB-guanine was studied using the model system of rat liver microsomes and human liver. It was observed that AFB-guanine is metabolized by glycosylases, which act on purines and pyrimidines. The glycosylase activity was inhibited by dicoumarol, which results in a decrease in the amount of AFB-guanine that is converted to adenosine triphosphate (ATP). The study also showed that histological analysis revealed degenerative diseases and cancer in mice fed with AFB-guanine, suggesting that this compound may be carcinogenic.Formule :C22H17N5O8Degré de pureté :Min. 95%Masse moléculaire :479.4 g/molN6-Propargyladenosine
CAS :N6-Propargyladenosine is an alkyne functionalised nucleoside.Formule :C13H15N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :305.29 g/mol2'-Deoxy-N2-isobutyryl-5'-O-levulinoylguanosine 3'-CE phosphoramidite
The 2'-deoxy-N2-isobutyryl-5'-O-levulinoylguanosine 3'-CE phosphoramidite is a high quality and novel nucleoside. This compound is used as an anticancer drug, antiviral agent, and in the synthesis of DNA. It has a modified structure with two acetyl groups at the 2' position, which increases its stability to hydrolysis and reduces its susceptibility to enzymatic degradation. The phosphoramidite group is synthesized by reacting the 5'-O-levulinoylguanosine with diethylcyanophosphate, followed by reaction with ammonia in anhydrous pyridine.Formule :C28H42N7O8PDegré de pureté :Min. 95%Masse moléculaire :635.65 g/mol2'/3'-O-Trinitrophenyl-adenosine-5'-triphosphate triethylammonium salt - 10mM aqueous solution
CAS :2'/3'-O-Trinitrophenyl-adenosine-5'-triphosphate triethylammonium salt - 10mM aqueous solution is a synthetic nucleoside that contains a phosphate group. It is an activator and anti-cancer agent that has been modified to be novel and high quality. This product has been shown to have antiviral, antibacterial, and anticancer properties. 2'/3'-O-Trinitrophenyl-adenosine-5'-triphosphate triethylammonium salt - 10mM aqueous solution is used in the treatment of HIV/AIDS, which may be due to its ability to inhibit viral DNA synthesis.Formule :C16H17N8O19P3Degré de pureté :Min. 95%Masse moléculaire :718.27 g/mol5'-O-DMT-2'-O-hexylphthalimidocytidine
5'-O-DMT-2'-O-hexylphthalimidocytidine is a novel anticancer drug that belongs to the class of nucleosides. It is an analog of cytidine, with a modified phosphoramidate linkage to the 5' carbon atom. This phosphoramidate linkage prevents the spontaneous hydrolysis of 5'-O-DMT-2'-O-hexylphthalimidocytidine, which inhibits DNA and RNA synthesis. The synthetic process for this compound is straightforward and the yield is high. 5'-O-DMT-2'-O-hexylphthalimidocytidine has been shown to be effective against some strains of HIV in vitro and in vivo, as well as some antiviral agents such as herpes simplex virus type 1 (HSV1) and varicella zoster virus (VZV).Formule :C44H46N4O9Degré de pureté :Min. 95%Masse moléculaire :774.28 g/mol3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine
CAS :3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine is an antitumor agent that belongs to the class of heterocyclic ring. It is a pyridinium salt with a benzoic acid residue at position 3 and 5'. The heterocyclic ring is derived from alkylene, which has two double bonds in the chain. This compound has low toxicity and can be synthesized from chloroform, fluorouridine, and pyridine. 3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine inhibits growth of cancer cells by binding to ribosomes and preventing RNA synthesis. It also acts as an alkylating agent that binds to DNA, leading to crosslinking between strands of DNA. This leads to cell death by apoptosis or necrosis due to interference with DNA replication.Formule :C13H15FN2O7Degré de pureté :Min. 95%Masse moléculaire :330.27 g/mol
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