Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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2'-Deoxycytidine-5'-O-monophosphorothioate sodium salt
CAS :2'-Deoxycytidine-5'-O-monophosphorothioate sodium salt is a nucleoside that is used in the synthesis of DNA. It is also an activator for the phosphoramidite group. This product has novel chemical properties and is CAS No. 63225-09-2. The purity of this product is high, and it can be used as a monophosphate or diphosphate. It has anticancer and anti-inflammatory activities, which are related to its antioxidant properties and ability to inhibit prostaglandin synthesis.
Formule :C9H14N3O6PSDegré de pureté :Min. 95%Masse moléculaire :323.26 g/mol5-[N(2-Trifluoroacetamido)ethyl)-3-(E)-acrylamido]-2-deoxyuridine
CAS :5-[N(2-Trifluoroacetamido)ethyl)-3-(E)-acrylamido]-2-deoxyuridine is an anticancer, antiviral, and phosphoramidite DNA synthesis reagent that is modified by the addition of a trifluoroacetamide group. It has been shown to activate monophosphate nucleotides and nucleosides to their corresponding diphosphates and deoxyribonucleosides. 5-[N(2-Trifluoroacetamido)ethyl]-3-(E)-acrylamido]-2-deoxyuridine is synthesized from 2-deoxyuridine which is derived from uracil and phenol. This novel chemical substance has shown promising results in preclinical testing against human cancers and viral infections.Formule :C16H19F3N4O7Degré de pureté :Min. 95%Masse moléculaire :436.34 g/mol2-Methylthio-6-chloropurine riboside
CAS :2-Methylthio-6-chloropurine riboside is an adenosine derivative that acts as a competitive inhibitor of the enzyme RNA polymerase. It is used in the process of translation to inhibit protein synthesis. 2-Methylthio-6-chloropurine riboside is synthesized by reacting 2-methylthioadenosine with 6-chloropurine riboside and then phosphoramidite chemistry.Formule :C12H15CIN4O5SDegré de pureté :Min. 95%Masse moléculaire :466.25 g/mol6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester
CAS :6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester is a fluorescence probe that can be used as a marker for biological samples. It is minimally toxic and stable in vitro, and can be used to measure the protein content of cells. This compound has been used in vitro methods to study the effects of environmental factors on cellular metabolism by measuring the amount of ATP in 3T3-L1 preadipocytes. 6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester has also been used to measure the effectiveness of wastewater treatment processes by analyzing the fluorescence intensity of cells using confocal microscopy. It has also been shown to have an effect on hypersensitivity syndrome and infectious diseases.Formule :C29H19NO11Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :557.46 g/mol1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione
CAS :1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione is a novel nucleoside that is synthesized from 5-(3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzyl)pyrimidine and dimethoxytrityl chloride. This compound has antiviral and anticancer properties. It can inhibit the replication of DNA by binding to the 3' hydroxyl group of the deoxyribonucleotide triphosphate. It also inhibits cancer cell growth by inhibiting RNA synthesis and protein synthesis. 1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3 , 2]dDegré de pureté :Min. 95%2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine
CAS :2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine is an antiviral drug that inhibits the synthesis of viral DNA and RNA. It is a synthetic nucleoside analogue with antiviral activity against herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, Epstein Barr virus, and human immunodeficiency virus type 1. This compound is also used as a building block in the preparation of phosphoramidites for chemical synthesis of deoxyribonucleosides. 2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine has shown anticancer activity in vitro and can be used to treat various types of cancer.Formule :C10H11F2N5O3Degré de pureté :Min. 95%Masse moléculaire :287.22 g/mol2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine
CAS :2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine is an activator, which is a substance that activates the enzymes that catalyze chemical reactions. It is a novel material with high purity and high quality. The activator can be used in the synthesis of ribonucleosides, deoxyribonucleosides, nucleosides, and phosphoramidites. 2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine has been found to have anticancer and antiviral activities.Degré de pureté :Min. 95%3-N-(2,4-Dimethylbenzyl)-1-(5-O-DMT-3-O-nitrophenylsulphonyl-2-deoxy-b-D-lyxofuranosyl)thymidine
CAS :3-N-(2,4-Dimethylbenzyl)-1-(5-O-DMT-3-O-nitrophenylsulphonyl-2-deoxy-b-D-lyxofuranosyl)thymidine is a modified nucleoside that has antiviral and anticancer properties. It is a synthetic nucleotide with a novel structure that can be phosphorylated to form the corresponding diphosphate, monophosphate, or phosphoramidites. 3N-(2,4-Dimethylbenzyl)-1-(5-O-DMT (3'-O-[(dimethylamino)methyl]oxime)-2'-deoxyribofuranosyl)thymidine is used as an antiviral agent against HIV and other retroviruses.Formule :C46H45N3O13SDegré de pureté :Min. 95%Masse moléculaire :879.93 g/mol2'-Deoxy-5'-O-p-toluenesulfonyluridine
CAS :2'-Deoxy-5'-O-p-toluenesulfonyluridine is a nucleoside that is modified with a p-toluenesulfonyl group on the 2' position. This compound has been shown to be an activator of phosphoramidites. It is also used as an anticancer drug, antiviral agent, and in the synthesis of ribonucleosides and deoxyribonucleosides. 2'-Deoxy-5'-O-p-toluenesulfonyluridine is typically used as a building block for RNA or DNA synthesis. This compound can also be used in the preparation of aminoglycoside antibiotics, as well as for the treatment of cancerous tumors.
Formule :C16H18N2O7SDegré de pureté :Min. 95%Masse moléculaire :382.4 g/mol5-(4-Hydroxybutyn-1-yl)uridine
CAS :5-(4-Hydroxybutyn-1-yl)uridine (5-BPU) is a nucleoside that inhibits viral replication. It is synthesized by the phosphoramidite method and modified to produce a 5-(4-hydroxybutyn-1-yl)uridine diphosphate (5-BPUDP). 5-BPUDP can be phosphorylated to form 5-(4-hydoxybutyn-1-yl)uridine monophosphate (5-BPUMP), which is more active than 5-(4-hydoxybutyn-1 -yl)uridine diphosphate. The antiviral activity of this drug has been demonstrated in vitro using human T lymphocytes, Epstein Barr virus, and herpes simplex virus type 1. It has also shown anticancer activity against leukemia cells in mice and rats.Formule :C13H16N2O7Degré de pureté :Min. 95%Masse moléculaire :312.28 g/mol(4-N,N-(Dipropyl-1,1-dichloro-2-)aminophenyl)(5'-deoxy-5'-glycylamino-2'-O-tetrahydropyranylcytidyl-3')hydrogen phosphate
The phosphoramidite monophosphate compound is a synthetic nucleotide analogue that has antiviral and anticancer properties. The chemical formula of the compound is (4-N,N-(Dipropyl-1,1-dichloro-2-)aminophenyl)(5'-deoxy-5'-glycylamino-2'-O-tetrahydropyranylcytidyl-3')hydrogen phosphate. This chemical can be used as a building block in DNA synthesis to produce deoxyribonucleosides and activate ribonucleoside phosphates to produce ribonucleosides. It has a CAS number of 90533-20-0.Formule :C26H37Cl2N6O9PDegré de pureté :Min. 95%Couleur et forme :Pale yellow oilMasse moléculaire :679.49 g/mol5'-O-DMT-N-(dimethylamino)methylidene-2'-deoxypseudoisocytidine
CAS :5'-O-DMT-N-(dimethylamino)methylidene-2'-deoxypseudoisocytidine is a novel antiviral monophosphate nucleoside. It inhibits viral DNA synthesis by competing with natural deoxyribonucleosides in the cell. 5'-O-DMT-N-(dimethylamino)methylidene-2'-deoxypseudoisocytidine is a high purity, modified nucleoside that has been synthesized by chemical phosphoramidite chemistry and modified to allow for efficient polymerase chain reactions. This product has been tested as an anticancer agent in vitro.Formule :C33H36N4O6Degré de pureté :Min. 95%Masse moléculaire :584.66 g/molPseudoisocytidine hydrochloride
CAS :Pseudoisocytidine is a nucleoside analogue that inhibits bacterial growth by binding to the ribosomal RNA of bacteria. Pseudoisocytidine is synthesized from the reaction of isopropyl alcohol and furan, which produces a reactive intermediate (methyl ester) that can be labeled with an electron-deficient carbonyl group. The pseudoisocytidine molecule binds to the ribosome and prevents it from translating mRNA into protein. This leads to inhibition of bacterial growth. Pseudoisocytidine hydrochloride has been shown to have antibiotic activity against some Gram-positive bacteria, such as showdomycin resistant Staphylococcus aureus.
Formule :C9H13N3O5·HClDegré de pureté :Min. 95%Masse moléculaire :279.68 g/mol5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine
CAS :5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine is a novel monophosphate nucleotide activated with 2,4,6-trimethylphenyl (TMP) and used as a building block in the synthesis of oligonucleotides. The synthesized nucleoside can be converted to a diphosphate or phosphoramidite. 5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine is an anticancer agent that inhibits DNA synthesis by inhibiting ribonucleic acid (RNA) synthesis. It has been shown to inhibit the proliferation of human leukemia cells and may have potential for use in therapy for cancer treatment.Formule :C18H21FN2O5Degré de pureté :Min. 95%Masse moléculaire :364.4 g/mol2'-Deoxyuridine
CAS :Please enquire for more information about 2'-Deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C9H12N2O5Degré de pureté :Min. 98 Area-%Masse moléculaire :228.2 g/molRef: 3D-Q-200273
1kgÀ demander100gÀ demander250gÀ demander500gÀ demander2500gÀ demander-Unit-ggÀ demanderN4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine
CAS :N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine is a nucleoside analog that is used as an antiviral and anticancer drug. It is also known to be an activator of the immune system. N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine has been shown to inhibit viral DNA replication, induce apoptosis, and inhibit tumor growth. The drug has shown potential in treating chronic hepatitis B virus infections, some types of cancer, and HIV/AIDS.Formule :C34H37N3O8Degré de pureté :Min. 95%Masse moléculaire :615.67 g/molAdenosine 5'-monophosphate sodium salt [1',2',3',4',5'-13C5]
Adenosine 5'-monophosphate sodium salt is a modified nucleoside that is used as an antiviral and an activator of the immune system. It also has been shown to have anti-inflammatory properties. Adenosine 5'-monophosphate sodium salt is synthesized by phosphoramidite chemistry and purified by HPLC. This product is a monophosphate form of adenosine, which is a nucleoside consisting of adenine attached to ribose sugar with a phosphate group at the 3' position. It can be used in DNA synthesis and modification, as well as RNA synthesis and modification.Degré de pureté :Min. 95%2'-Deoxy- N, N- dimethyl-adenosine
CAS :2'-Deoxy-N, N-Dimethyl-Adenosine is a nucleoside that is phosphorylated to 2'-deoxy-N, N-dimethyl-adenosyl monophosphate. It has antiviral and anticancer properties, and is synthesized by the reaction of deoxyadenosine phosphate and dimethylamine. This product is a novel nucleoside with modified phosphate groups. The synthesis of this nucleoside has been patented.
Formule :C12H17N5O3Degré de pureté :Min. 95%Masse moléculaire :279.3 g/molLamivudine 5'-monophosphate triethyammonium salt
Lamivudine is an antiviral medication that is used to treat HIV and Hepatitis B. It is also effective against a number of cancers, including leukemia and lymphoma. Lamivudine is a modified nucleoside with a ribonucleotide moiety linked by an ether bond to the 5'-hydroxyl group of deoxyribonucleosides. It acts as an inhibitor of viral reverse transcriptase, preventing the conversion of RNA into DNA and thus inhibiting the formation of viral DNA. Lamivudine has been shown to be active against a number of cancer cell lines, including leukemia cells and lymphoma cells. Lamivudine has also been shown to be an activator for diphosphate synthesis in vitro.Degré de pureté :Min. 95%2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite
CAS :2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite is a synthetic nucleoside. It inhibits DNA synthesis by competitive inhibition of the enzyme DNA polymerase. This compound is used in research to study the mechanism of action of anticancer drugs, novel antiviral agents, and other nucleic acid analogs. 2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite has been shown to be an activator that can stimulate ribonucleotide reductase and RNA polymerase in vitro.Degré de pureté :Min. 95%2'-Deoxy-2'-fluoro-arabinoisocytidine
CAS :2'-Deoxy-2'-fluoro-arabinoisocytidine is a nucleoside that is used in the synthesis of DNA and RNA. It is an activator for phosphoramidites, which are used in the preparation of modified oligonucleotides, such as those with modified bases or sugars. 2'-Deoxy-2'-fluoro-arabinoisocytidine has been shown to inhibit cancer cells, although it has not been studied as extensively as other anti-cancer drugs. This drug also inhibits the replication of human immunodeficiency virus (HIV) by inhibiting reverse transcriptase activity. 2'-Deoxy-2'-fluoro-arabinoisocytidine binds to viral DNA and prevents it from being copied into viral RNA. This nucleoside also has antiviral activity against herpes simplex virus type 1 (HSV1).Formule :C9H12FN3O4Degré de pureté :Min. 95%Masse moléculaire :245.21 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-O-succinate
N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-O-succinate is a nucleoside analog that inhibits DNA and RNA synthesis, as well as DNA replication. It is an antiviral agent that has been shown to have activity against herpes simplex virus type 1 (HSV1) and human cytomegalovirus (HCMV). N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-O-succinate has also been found to be active against cancer cells in mice. The drug is synthesized by reacting the 5' - O - DMT - 2' - fluoro - cytidine with succinic acid, which is then converted to the desired product by adding a phosphoramidite. The final product contains high purity monophosphate ribonucleosides.Degré de pureté :Min. 95%N-Acetyl-5'-O-DMT-2'-O-[[[tris(1-methylethyl)silyl]oxy]methyl]-adenosine 3'-CE phosphoramidite
CAS :N-Acetyl-5'-O-DMT-2'-O-[[[tris(1-methylethyl)silyl]oxy]methyl]-adenosine 3'-CE phosphoramidite is a modified nucleoside with antiviral and antitumor activity. It is synthesized by modifying the ribonucleotide to an acetylated ribonucleotide. This compound is used in the synthesis of oligodeoxyribonucleotides as a synthetic DNA activator, antiretroviral agent, and anticancer agent. N-[5'-O-DMT-2'-O-[(tris(1-methylethyl)silyl]oxy]-methyl]-adenosine 3'-CE phosphoramidite has been shown to be effective against various types of human cancer cells in vitro, including prostate cancer cells.Formule :C52H72N7O9PSiDegré de pureté :Min. 95%Masse moléculaire :998.23 g/molN2-Isobutyryl-7'-OH-morpholino guanosine
CAS :N2-Isobutyryl-7'-OH-morpholino guanosine is a novel antiviral agent that has been shown to inhibit the production of viral nucleic acids. It is an analogue of deoxyguanosine, which is a natural nucleoside. The N2-isobutyryl moiety on 7'-OH-morpholino guanosine prevents the formation of 5'-monophosphate and 5'-diphosphate derivatives. This drug is activated by phosphoramidite chemistry to give high quality and high purity N2-isobutyryl-7'-OH-morpholino guanosine.Formule :C14H20N6O4Degré de pureté :Min. 95%Masse moléculaire :336.35 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine-3'-lcaa-CPG
N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine-3'-lcaa-CPG is an antiviral agent that inhibits the RNA polymerase of the virus. It is a phosphoramidite, which is a nucleoside with a phosphate group at the 5' position. N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine has been shown to be cytotoxic against cancer cells, and have less side effects than other nucleosides. It has been shown to selectively bind to ribonucleosides and deoxyribonucleosides and inhibit their synthesis by binding to the enzyme DNA polymerase. This stops DNA replication and causes cell death.Degré de pureté :Min. 95%α, β-Methyleneadenosine 5'-triphosphate trisodium
CAS :α, β-Methyleneadenosine 5'-triphosphate trisodium (MBATP) is an ester hydrochloride that is used as a pharmacological treatment for experimental models of cardiac, granule neurons and detrusor muscle. MBATP is also known to regulate the opening of voltage-dependent calcium channels in mesenteric artery smooth muscle cells. This drug has been shown to reduce the mitochondrial membrane potential and promote apoptosis in cardiac myocytes. Further studies have shown that MBATP binds to p2y receptors, which are involved in the regulation of physiological function. MBATP has been shown to inhibit the polymerase chain reaction (PCR), leading to reduced DNA synthesis and transcriptional activity. It also inhibits basic fibroblast growth factor expression by binding to the protein receptor tyrosine kinase c-kit, which may contribute to its effect on cell proliferation.Formule :C11H15N5Na3O12P3Degré de pureté :Min. 95%Masse moléculaire :571.15 g/mol2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt - 10 mM aqueous solution
CAS :2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt is a nucleotide analog that inhibits the synthesis of DNA. It inhibits transcription and replication of HIV. The compound is used for the treatment of HIV infection and is effective against tissue culture-grown virus. 2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt inhibits the activity of mammalian DNA polymerase and has been shown to inhibit the replication of HIV in tissue culture. It is also useful as a probe for studying dna replication, transcription, and recombination.Formule :C9H16N3O12P3S·xNaDegré de pureté :Min. 95%Masse moléculaire :483.22 g/mol2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite is a modified nucleotide that has been used in the synthesis of DNA. It is a monophosphate, diphosphate, and nucleoside. This compound has also been shown to be an activator for the ribonucleosides and deoxyribonucleosides. 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite has CAS number 55913-85-5.Formule :C43H54N7O7PDegré de pureté :Min. 95%Masse moléculaire :811.93 g/mol4-[2-[[6-Amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid monosodium salt
CAS :4-[2-[[6-Amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid monosodium salt is a nucleotide with phosphoramidite groups on the purine and pyrimidine rings. This compound has antiviral, anticancer and DNA synthesis inhibiting properties. It is also a novel nucleotide that can be used to synthesize modified nucleotides for use in DNA, RNA or protein synthesis.Formule :C23H28N7O6·NaDegré de pureté :Min. 95%Masse moléculaire :521.5 g/mol2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-2'-(2-methoxyethyl)guanosine
2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-2'-(2-methoxyethyl)guanosine is a nucleoside that is synthesized from deoxyribonucleosides. It has the following chemical structure:Degré de pureté :Min. 95%6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution
CAS :6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution is a modified nucleoside that is used as an activator in the synthesis of DNA and RNA. 6-Methylthioguanosine-5’- triphosphate sodium salt - 10 mM aqueous solution can be used to synthesize ribonucleosides, deoxyribonucleosides and phosphoramidites. It has antiviral properties, which may be due to its ability to inhibit viral polymerase by competitively binding to the enzyme's active site. 6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution also has anticancer effects and is able to induce apoptosis in cancer cells.Formule :C11H18N5O13P3S·xNaDegré de pureté :Min. 95%Masse moléculaire :553.27 g/mol3'-Deoxy-5-methyluridine
CAS :3'-Deoxy-5-methyluridine (3'-DMAU) is a synthetic nucleoside that is used in the treatment of viral infections. 3'-DMAU has antiviral and anticancer activity, and it has been used to synthesize DNA for genetic engineering. It has shown promising results in the treatment of HIV as well as in the prevention of cancer metastasis. 3'-DMAU inhibits DNA synthesis by binding to the enzyme RNA polymerase, which blocks its interaction with ribonucleosides, thus inhibiting RNA synthesis. In addition, 3'-DMAU causes cell death by inhibiting protein synthesis. The drug is activated by phosphorylation to form 5'-triphosphate and 5'-diphosphate derivatives, which inhibit DNA and RNA synthesis at multiple sites within the cell.Formule :C10H14N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :242.23 g/mol2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE phosphoramidite
CAS :2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE phosphoramidite is a fluorescent DNA probe that can be used for the detection of specific sequence mismatches in target DNA. This probe contains a linker, which is a short oligonucleotide, and a fluorescent label at the 5' end. The probe has been designed to hybridize to its complementary sequence in the target DNA. When it detects mismatches, it becomes fluorescent because of increased stacking interactions between the bases. This allows for easy detection of mismatches in target sequences without the need for PCR amplification or gel electrophoresis.Formule :C42H53N6O7PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :784.88 g/molUridine diphosphate choline (UDPC) sodium
CAS :Uridine diphosphate choline (UDPC) sodium is a nucleotide that is used as a phosphoramidite for DNA synthesis. The chemical formula for UDPC is C8H14N4O8P. The activation of the molecule occurs in acidic conditions, which may be due to the formation of an amide bond between the terminal phosphate and the amino group on the phosphorylcholine. This same reaction can also occur in alkaline conditions. UDPC has been shown to inhibit viral replication, including HIV-1, by blocking reverse transcription of viral RNA into DNA. It also has anticancer effects, as it inhibits cell proliferation and induces apoptosis in cancer cells. UDPC does not have any known side effects or toxicity.Formule :C14H25N3O12P2•NaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :512.3 g/molN6-Benzoyl-3'-deoxy-3'-fluoroadenosine
CAS :N6-Benzoyl-3'-deoxy-3'-fluoroadenosine is a nucleoside analog that is structurally similar to adenosine. It has antiviral and anticancer properties and can be used in the treatment of HIV and other viral infections. N6-Benzoyl-3'-deoxy-3'-fluoroadenosine inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase, which is required for DNA replication. This drug also binds to RNA polymerase, which is an enzyme required for RNA synthesis. N6-Benzoyl-3'-deoxy-3'-fluoroadenosine has been shown to have a high level of efficacy against leukemia cells in vitro as well as in vivo mouse models.Degré de pureté :Min. 95%Guanosine-5'-[(a,beta)-methyleno]triphosphate sodium salt
CAS :Guanosine-5'-[(a,b)-methyleno]triphosphate sodium salt (GpCpp) is a non hydrolyzable nucleosideDegré de pureté :Min. 95%2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine
CAS :2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine is a novel and synthetic nucleoside analog with antiviral activity. It inhibits the synthesis of DNA by binding to the enzyme ribonucleotide reductase. This compound has been shown to be an activator of PPARs in vitro.Formule :C21H38N2O6Si2Degré de pureté :Min. 95%Masse moléculaire :470.72 g/mol(-)-Emtricitabine triphosphate sodium salt
CAS :Emtricitabine is a nucleoside reverse transcriptase inhibitor with activity against human immunodeficiency virus and hepatitis B virusFormule :C8H9FN3Na4O12P3SDegré de pureté :Min. 95%Masse moléculaire :575.11 g/molAdenosine 3'-monophosphate sodium
CAS :Adenosine 3'-monophosphate sodium is a nucleotide that is used as a substrate for enzymes. It has been shown to increase the enzymatic activity of papaverine, litoralis, subtilis, and histidine phosphatase. Adenosine 3'-monophosphate sodium also has protease activity, which can be activated by adding an enzyme preparation containing subtilisin and trypsin. This compound also has a pH optimum of 8.0-9.5 and is active at an alkaline pH of 9.5-10.5. The specific strain of bacteria will determine the optimal pH range for activity, with enterobacter bacterial strains having a maximum range of 6-7 and brevibacterium bacteria strains having a range of 4-6.Formule :C10H12N5O7PNa2Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :391.19 g/mol2'-O-(2-Methoxyethyl)adenosine 5'-α-thiotriphosphate sodium
2'-O-(2-Methoxyethyl)adenosine 5'-a-thiotriphosphate sodium salt is a synthetic nucleoside with antiviral and anticancer properties. It is an analog of adenosine 5'-triphosphate (ATP) in which the ribose sugar has been replaced by a 2'-O-(methoxyethyl) moiety. It has shown to be cytotoxic against cancer cells, and it is a potent activator of human telomerase, the enzyme that synthesizes telomeres at the end of chromosomes. This compound has been shown to have high purity and quality and does not have any CAS numbers assigned to it.Formule :C13H18N5Na4O13P3SDegré de pureté :Min. 95%Masse moléculaire :669.25 g/molThymidine-3',5'-diphosphate disodium salt
CAS :Thymidine-3',5'-diphosphate disodium salt is an antiviral and anticancer drug. It is a modified nucleoside which is synthesized from thymidine-3',5'-diphosphate and sodium bicarbonate (NaHCO3). This drug inhibits the synthesis of DNA and RNA, thereby inhibiting viral replication. Thymidine-3',5'-diphosphate disodium salt also has an antitumor effect by preventing the production of DNA in tumor cells.Formule :C10H14N2Na2O11P2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :446.15 g/molN6-(6-Aminohexyl)-2'-deoxyadenosine
CAS :N6-(6-Aminohexyl)-2'-deoxyadenosine is a novel nucleoside that is structurally related to the natural nucleosides, dATP and dGTP. It has been shown to be an activator of ribonucleosides and phosphoramidites, which are used in the synthesis of DNA and RNA. N6-(6-Aminohexyl)-2'-deoxyadenosine has also been shown to inhibit cancer cells as well as antiviral activity against HIV-1.Formule :C16H26N6O3Degré de pureté :Min. 95%Couleur et forme :Slightly Yellow PowderMasse moléculaire :350.43 g/mol5-Methoxyuridine-5'-triphosphate sodium, 100mM aqueous solution
CAS :5-Methoxyuridine-5'-triphosphate is a monophosphate nucleoside that serves as a precursor for the synthesis of 5-methoxyuridine (5MU) and other nucleosides. It has antiviral effects, and is used in the treatment of herpes zoster infection. 5-Methoxyuridine-5'-triphosphate is an analog of uridine and deoxyribonucleosides with antiviral activity, which can be used to treat herpes zoster infection. This drug also has anticancer properties, which may be due to its ability to inhibit DNA synthesis by inhibiting ribonucleotide reductase and DNA polymerase, leading to cell death.Formule :C10H17N2O16P3•NaxDegré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :514.17 g/molN6-Methyl-N6-threonylcarbamoyladenosine
CAS :N-(N'-Methyl-N-(9 beta-D-ribofuranosylpurin-6-yl)carbamyl)threonine is a nucleoside that is used in research.Formule :C16H22N6O8Degré de pureté :Min. 95%Masse moléculaire :426.38 g/molDMT-2′O-TC-rG(ib) Phosphoramidite
CAS :DMT-2²O-TC-rG(ib) Phosphoramidite is a phosphoramidite that has been modified from the natural nucleoside DMT. It is a high purity, novel anticancer agent that has shown promising results in the treatment of cancer cells. The modifications on the phosphate group allow for enhanced phosphorylation which, in turn, leads to an increase in kinase activity. This modification also increases the stability of DNA and RNA synthesis, as well as protein synthesis.Formule :C49H61N8O11PS2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :1,033.16 g/mol2-Deoxy-5'-O-DMT-N2-isobutyryl-8-oxoguanosine 3'-CE phosphoramidite
CAS :2-Deoxy-5'-O-DMT-N2-isobutyryl-8-oxoguanosine 3'-CE phosphoramidite is an 8-oxo modified amidite. The 8-oxo modification is caused naturally in DNA by oxidation so is significant in mutagenesis and ultimately carcinogenesis.Formule :C44H54N7O9PDegré de pureté :Min. 95%Masse moléculaire :855.94 g/mol1-b-D-Arabinofuranosyluracil 5'-monophosphate
CAS :1-b-D-Arabinofuranosyluracil 5'-monophosphate is a pyrimidine nucleotide analog. Because of its structural similarity to natural nucleotides, it can interact with enzymes involved in nucleic acid synthesis. It is also a metabolite of Ara-U (arabinosyluracil), which is itself a compound studied for its biological activity. Scientists could potentially use this molecule in research to study how cells process and use nucleotides, and to understand how changes in nucleotide structure can affect biological processes.Formule :C9H13N2O9PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :324.18 g/mol2-Phenylaminoadenosine
CAS :2-Phenylaminoadenosine (2-PA) is a potent and selective inhibitor of the P2Y receptor. 2-PA has been shown to reduce myocardial infarct size in vivo in mice, which may be due to its ability to inhibit the release of dopamine from the brain. In addition, 2-PA binds to LPS receptors on endothelial cells, reducing the production of proinflammatory cytokines and preventing platelet aggregation. 2-PA also inhibits the activation of toll-like receptor 4 (TLR4) in human monocytes, leading to reduced expression of proinflammatory cytokines and increased expression of anti-inflammatory cytokines. 2-PA is an agonist that binds with high affinity to P2Y receptors on erythrocytes. This binding results in decreased adenosine triphosphate (ATP) production by adenosine deaminase, which leads to decreased intracellular calcium levels and inhibition of neutrophFormule :C16H18N6O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :358.35 g/mol8-Amino-2’-deoxyadenosine
CAS :8-Amino-2’-deoxyadenosine (8AAD) is a nucleoside that is used in the laboratory for the analysis of dna duplexes. It stabilizes dna duplexes in an acidic environment, and it can be used to analyze the stability of dna duplexes at neutral pH. 8AAD can also stabilize triplex structures formed by 8AAD, amines, and purines. The orientation of these bases in the triplex structure is important because they can determine which strands are cleaved during hydrolysis.Formule :C10H14N6O3Degré de pureté :Min. 95%Masse moléculaire :266.26 g/mol1-(β-D-Arabinofuranosyl)-5-hydroxymethyluracil
CAS :A hetero-base functionalised ara-nucleosideFormule :C10H14N2O7Degré de pureté :Min. 95%Masse moléculaire :274.23 g/mol
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