
Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3567 produits trouvés pour "Nucléosides"
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N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-trifluoroacetamidocytidine
<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-trifluoroacetamidocytidine is a novel nucleoside analog that is activated by ribonucleotide reductase. This compound inhibits the synthesis of DNA and RNA in cells, which leads to the inhibition of cellular proliferation. N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-trifluoroacetamidocytidine has been shown to be effective against cancer cells, as well as antiviral and antiretroviral activity. It is also active against drug resistant strains of HIV.</p>Formule :C39H35F3N4O8Degré de pureté :Min. 95%Masse moléculaire :744.71 g/mol2-(sec-Butylthio)pyrimidine-5-carbaldehyde
CAS :<p>2-(sec-Butylthio)pyrimidine-5-carbaldehyde is a molecule that inhibits cell growth and angiogenesis. It was found to inhibit the phosphorylation of specific proteins, leading to the inhibition of cell growth and angiogenesis. This compound has been shown to be effective against prostate cancer cells in vitro and in vivo, as well as in a mouse model for breast cancer. In this model, the drug inhibited tumor growth without any apparent toxicity to normal tissues. 2-(sec-Butylthio)pyrimidine-5-carbaldehyde has been tested as a potential antiangiogenic agent in mice, with results showing no adverse effects on animals.</p>Formule :C9H12N2OSDegré de pureté :Min. 95%Masse moléculaire :196.27 g/molStavudine 5'-monophosphate triethyammonium salt
<p>Stavudine 5'-monophosphate triethylammonium salt is a nucleoside analog that is structurally related to the natural deoxyribonucleosides. It has antiviral activity and is used in the treatment of HIV-1. Stavudine 5'-monophosphate triethylammonium salt inhibits viral replication by inhibiting DNA polymerase, which leads to a decrease in the production of new copies of the virus. This drug has also been shown to have anticancer properties, although it is not currently approved for this use. Stavudine 5'-monophosphate triethylammonium salt is synthesized in high purity and high quality, with a CAS number of 102747-23-2.</p>Degré de pureté :Min. 95%8-Methoxyadenosine
CAS :<p>8-Methoxyadenosine is an acidic adenosine that acts as a competitive antagonist of the A1 receptor. It has a high affinity for this receptor and blocks the binding of adenosine to the receptor, thereby inhibiting its function. 8-Methoxyadenosine is also a competitive antagonist of the uridine nucleotide, which inhibits enzymatic catalysis by ribonucleoside kinase and ribonucleotide reductase. It has been shown to have properties similar to those of other pyrimidine nucleosides such as cytidine, thymine, and uridine. This molecule has a hydroxyl group in its structure, which is essential for binding to these enzymes. 8-Methoxyadenosine also has a phosphate group in its structure, which is necessary for the synthesis of DNA or RNA from deoxyribonucleotides. The benzoate group in 8-methoxyadenosine's structure makes</p>Degré de pureté :Min. 95%NPOM-Caged-dT CEP
CAS :<p>Please enquire for more information about NPOM-Caged-dT CEP including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C50H58N5O13PDegré de pureté :Min. 95%Masse moléculaire :968 g/molN4-Ethyl-2'-deoxycytidine
CAS :<p>N4-Ethyl-2'-deoxycytidine is a novel nucleoside analog that inhibits the activity of DNA polymerase. It is used as an anticancer, antiviral and antiretroviral agent. N4-Ethyl-2'-deoxycytidine has been shown to be active against herpes simplex virus type 1 (HSV-1), HSV-2, cytomegalovirus (CMV), human immunodeficiency virus type 1 (HIV-1) and HIV-2 in vitro. This drug also has antiangiogenic properties due to its ability to inhibit the synthesis of vascular endothelial growth factor A. N4-Ethyl-2'-deoxycytidine is a modified nucleoside that can be phosphorylated by cellular enzymes, which activates it by converting it into a monophosphate or diphosphate form. This drug inhibits the production of RNA from DNA and also prevents protein</p>Formule :C11H17N3O4Degré de pureté :Min. 95%Masse moléculaire :255.27 g/molAdenine
CAS :<p>Adenine is a purine nucleoside that has guanine as its base. It has the chemical formula C5H5N5O and can be found in RNA, DNA, and ATP. Adenine is an important component of the human body because it is a key component of nucleic acids. It also plays a role in the regulation of metabolism and the production of energy. Adenine is one of the most abundant molecules in cells, making up 75% of DNA and 50% of RNA. Adenine is biosynthesized from aspartic acid by removing an amino group on aspartate to form oxaloacetate, which reacts with glyoxylate to form citric acid. This reaction requires vitamin B6 to function properly. The optimum concentration for adenine is between 10-100 mM, but it can be toxic at high concentrations (greater than 1 M). Adenine binds to sulfa drugs through hydrogen bonding interactions and also inhibits the enzyme x</p>Formule :C5H5N5Degré de pureté :Min. 98.0 Area-%Masse moléculaire :135.13 g/molRef: 3D-Q-200596
1kgÀ demander5kgÀ demander10kgÀ demander25kgÀ demander2500gÀ demander-Unit-kgkgÀ demanderN6-Monobutyryl-2'-deoxyadenosine 3',5'-cyclic monophosphate sodium salt
CAS :<p>N6-Monobutyryl-2'-deoxyadenosine 3',5'-cyclic monophosphate sodium salt is a novel antiviral and anticancer agent that is a synthetic nucleoside analogue. It has been shown to be effective at inhibiting the growth of human cancer cells in vitro and in vivo. N6-Monobutyryl-2'-deoxyadenosine 3',5'-cyclic monophosphate sodium salt binds to viral RNA, resulting in inhibition of protein synthesis and cell death.</p>Formule :C14H18N5O6P·NaDegré de pureté :Min. 95%Masse moléculaire :406.29 g/mol2',3',5'-Tri-O-acetylisoguanosine
CAS :<p>2',3',5'-Tri-O-acetylisoguanosine is a modified nucleoside with anticancer activity. It is a ribonucleoside that is deoxyribonucleosides, and it has been shown to be an activator of the diphosphate moiety in the enzyme DNA polymerase. This novel compound has antiviral and antibacterial properties, as well as anti-inflammatory activities. 2',3',5'-Tri-O-acetylisoguanosine (TAI) is also used as a monophosphate donor in phosphoramidite coupling reactions.</p>Formule :C16H19N5O8Degré de pureté :Min. 95%Masse moléculaire :409.35 g/mol2-(Methylthio)-4-(P-Tolylamino)Pyrimidine-5-Carboxylic Acid
CAS :<p>2-(Methylthio)-4-(P-tolylamino)pyrimidine-5-carboxylic acid is an anticancer drug that is a novel, modified nucleoside. It has been shown to be active as a monophosphate and diphosphate in vitro. 2-(Methylthio)-4-(P-tolylamino)pyrimidine-5-carboxylic acid has also been shown to have antiviral activity against HIV and herpes simplex virus type 1 (HSV1).</p>Formule :C13H13N3O2SDegré de pureté :Min. 95%Masse moléculaire :275.33 g/mol2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl]-uridine 3'-CE phosphoramidite
CAS :<p>2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl]-uridine 3'-CE phosphoramidite is a novel modified nucleoside that is synthesized by the reaction of 2'-deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl] uridine with bis(2,4,6-trimethylbenzoyl)phosphine and then with tetrazole. This product inhibits the synthesis of viral RNA and DNA and has been shown to be effective against cancer cells in vitro.</p>Formule :C44H49F3N5O9PDegré de pureté :Min. 95%Masse moléculaire :879.86 g/mol8-Bromoguanosine-5'-triphosphate sodium salt - 10 mM aqueous solution
CAS :<p>8-Bromoguanosine-5'-triphosphate sodium salt is a nucleotide analog that inhibits the enzyme ribonucleotide reductase. This drug inhibits bacterial growth by interfering with protein synthesis and cell division. It binds to the purine riboswitch, which is an allosteric regulatory binding site on the ribosome, inactivating it. 8-Bromoguanosine-5'-triphosphate sodium salt also binds to the active site of bacterial RNA polymerase and inhibits DNA synthesis. The activity of this drug has been shown using a bacteriophage system in which the enzyme protein synthesis was inhibited by 8-bromoguanosine-5'-triphosphate sodium salt.</p>Formule :C10H15N5O14P3Br·xNaDegré de pureté :Min. 95%Masse moléculaire :602.08 g/molN4-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-5-methylcytidine 3'-CE phosphoramidite
<p>N4-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-5-methylcytidine 3'-CE phosphoramidite is a novel, antiviral, and anticancer agent. It has high purity and quality, and is modified with an acetyl group (N4-benzoyl) at the 5' position of the nucleotide sugar. This product has a CAS No. of 636371-27-0 and may be used as a monophosphate or diphosphate. The N4-benzoyl group is not present in natural nucleosides; therefore, this analog can serve as an activator for ribonucleoside kinase by mimicking the natural substrate.</p>Degré de pureté :Min. 95%2,6-Dichloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-a-D-arabinofuranosyl)purine
<p>2,6-Dichloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-a-D-arabinofuranosyl)purine is a nucleoside that is used in the synthesis of antiviral drugs. It is a modified monophosphate with a 3',5'-di-O-benzoyl group and 2'-deoxyribose. This substance can be prepared from the corresponding 2,6-dichloropurine by reaction with chloroacetaldehyde diethyl acetal. 2,6 Dichloro 9-(3',5'-di-O-benzoyl) purine has been shown to have anticancer activity against various human cancer cell lines in vitro and in vivo.</p>Degré de pureté :Min. 95%5-Fluoro-1-(b-L-ribofuranosyl)-uracil
CAS :<p>5-Fluoro-1-(b-L-ribofuranosyl)-uracil is a triflate that is synthesized by the intramolecular, stereospecific reaction of l-guanosine and l-adenosine. It has been shown to have high yields in its synthesis. 5-Fluoro-1-(b-L-ribofuranosyl)-uracil can be used to produce glycosidations with d-galactose and l-thymidine. This product can also be used for the production of l-[5-(2,4,6-trimethoxybenzoyl)-1Hpyrazol]-3-[(2S,3R)-3-(bromomethyl)pyrrolidin]-2one (PBI), which is an inhibitor of protein kinase C.</p>Degré de pureté :Min. 95%2-Amino-9-(b-D-ribofuranosyl)purine 5'-O-triphosphate - 10mM aq. solution
CAS :<p>2-Amino-9-(b-D-ribofuranosyl)purine 5'-O-triphosphate is a synthetic nucleoside that is modified by phosphoramidite chemistry. This compound is an antiviral agent that inhibits viral DNA synthesis and replication. It has also been shown to have anticancer properties. 2-Amino-9-(b-D-ribofuranosyl)purine 5'-O-triphosphate inhibits the enzymatic activity of the enzyme ribonucleotide reductase, which converts ribonucleotides into deoxyribonucleotides. The resulting monophosphate form of this compound accumulates in cells, which leads to cell death.</p>Formule :C10H16N5O13P3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :507.18 g/mol3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine
<p>3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine (Zidovudine) is a nucleoside analog that inhibits the replication of human immunodeficiency virus type 1. It is phosphorylated by cellular enzymes to form the active triphosphate form, which incorporates into viral DNA and causes chain termination. Zidovudine has been used in the treatment of HIV infection and AIDS. This drug also has antiviral activity against other retroviruses such as HIV type 2 and measles virus, as well as some DNA viruses, such as herpes simplex type 1. Zidovudine may be useful for the treatment of cancer, particularly Kaposi's sarcoma.</p>Degré de pureté :Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-3-methyluridine 3'-CE phosphoramidite
CAS :<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-3-methyluridine 3'-CE phosphoramidite is a modified nucleoside that has antiviral and anticancer properties. It is synthesized by the reaction of 2'-O-tert-butyldimethylsilyl-5'-O-DMT (2,6-dimethoxytrityl) with 3 methyluridine. The compound has been shown to be an activator for DNA polymerase, ribonucleases and deoxyribonucleases in vitro. It also inhibits tumor cell proliferation and induces apoptosis in cultured cells. This compound is a high quality product with CAS number 179762-50-6 and is available at high purity.</p>Formule :C46H63N4O9PSiDegré de pureté :Min. 95%Masse moléculaire :875.07 g/mol4-(4-Bromophenyl)pyrimidine-2-thiol
CAS :<p>The dynamical module is a polluting, herbaceous, high pressure system. It has the following characteristics:</p>Formule :C10H7BrN2SDegré de pureté :Min. 95%Masse moléculaire :267.15 g/mol3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine
CAS :<p>3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine is a novel antiviral agent that has been synthesized as a high quality, high purity monophosphate. It is a modified nucleoside that is used to synthesize phosphoramidites. It has antiviral activity against herpes simplex virus type 1 and 2, and cytomegalovirus. 3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine is also an inhibitor of the DNA polymerase enzyme and inhibits the synthesis of viral DNA in infected cells. This drug can be used for the treatment of infections caused by these viruses.</p>Formule :C13H14BrFN2O7Degré de pureté :Min. 95%Masse moléculaire :409.16 g/mol2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde
CAS :<p>2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde is a Ribonucleside, Deoxyribonucleoside, Activator, Antiviral, Synthetic and Modified DNA Nucleoside. It has been shown to inhibit viral replication in vitro by interfering with the formation of the viral diphosphate. 2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde is a ribonucleotide that is synthesized from commercially available starting materials. This compound has shown to be active against HIV type 1 virus in vitro and has been proposed as a potential antiviral agent for the treatment of AIDS.<br>2-Methylsulfanyl-4-phenylamino pyrimidine 5 carbaldehyde (2MSAP) was found to be active against HIV type 1 virus in vitro and has been proposed as a potential antiviral agent for the treatment of</p>Formule :C12H11N3OSDegré de pureté :Min. 95%Masse moléculaire :245.3 g/mol5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine
CAS :<p>5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine is a nucleoside analog that is an activator of DNA polymerase. It has been shown to have anticancer activity in vitro and in vivo. 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine was found to inhibit the proliferation of leukemia cells, human colon cancer cells, and human prostate cancer cells. This compound also inhibits viral replication by affecting the synthesis of viral DNA and RNA. 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine may be used as a research tool for studying the mechanism of action of antiviral drugs such</p>Formule :C37H37F3N4O9Degré de pureté :Min. 95%Masse moléculaire :738.74 g/mol2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one
CAS :<p>2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one is a modified nucleoside analog with the following structure: the core heterocyclic structure is a fused imidazole-triazine ring, there is a 2-amino group at position 2 of the imidazole ring and it has a 2-deoxy-β-D-ribofuranose sugar attached at the 8-position of the heterocyclic ring, making it structurally related to DNA nucleosides.</p>Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :267.24 g/mol3'-Deoxy-L-thymidine
CAS :<p>3'-Deoxy-L-thymidine is a nucleoside analog that inhibits HIV replication by interfering with the synthesis of viral DNA. The drug binds to the enzyme thymidine phosphorylase, which converts thymidine into deoxyuridine monophosphate, and prevents conversion of deoxyuridine to deoxythymidine monophosphate. This leads to inhibition of both DNA synthesis and the production of RNA. 3'-Deoxy-L-thymidine has dose-limiting toxicity at high doses and is not active against other viruses such as herpes simplex virus or cytomegalovirus. It is metabolized in the liver by enzymes such as 5-fluorocytosine, which converts it into its active form, 5-fluorouracil.</p>Formule :C10H14N2O4Degré de pureté :Min. 95%Masse moléculaire :226.23 g/mol7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS :<p>7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt is a nucleoside analog that inhibits telomerase. It binds to the catalytic subunit of telomerase, which is an RNA-dependent DNA polymerase that synthesizes telomeres during DNA replication. This binding prevents the enzyme from extending the 3' end of the DNA strand, inhibiting cell proliferation and leading to apoptosis. Telomerase inhibition has been shown to have an inhibitory effect on insulin resistance in mice. 7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt also inhibits protein kinases, but does not inhibit phosphatases or other enzymes.</p>Formule :C11H17N4O13P3·xLiDegré de pureté :Min. 95%Masse moléculaire :506.19 g/mol5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine
<p>5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine is a nucleoside analog that has antiviral, anticancer, and high purity properties. It is an activated nucleotide that can be incorporated into DNA or RNA. 5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine is a modified nucleoside with the deoxyribose sugar replaced by an isopropylidene group. This modification prevents the drug from being metabolized and excreted from the body. The drug is used to treat various cancers such as leukemia and lymphoma, as well as herpes simplex virus infections. It also has been shown to have antimicrobial properties against bacteria, fungi, and viruses.</p>Formule :C12H15ClIN3O4Degré de pureté :Min. 95%Masse moléculaire :427.63 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite
CAS :<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite is an antiviral agent that inhibits the synthesis of DNA. It can be used to treat AIDS, because it inhibits the reverse transcriptase enzyme. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite also has anticancer properties, which is due to its ability to inhibit RNA and protein synthesis in cancer cells. This compound has been synthesized by reacting 5'-O-DMT cytidine with methylacetoacetate under standard conditions. The modified nucleoside has a high purity, high quality, and novel structure.</p>Formule :C47H64N7O7SiDegré de pureté :Min. 95%Masse moléculaire :867.14 g/molCaged Strand-Breaker II CE-Phosphoramidite
CAS :<p>When included in an oligonucleotide, irradiation at 365 nm causes strand cleavage. This will leave a hydroxyl residue on the 3' end and a phosphate on the 5' end.</p>Formule :C47H53N4O10PDegré de pureté :Min. 95%Masse moléculaire :864.92 g/mol4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-7-pteridone
<p>4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-7-pteridone is a novel nucleoside that has been modified by the addition of a 2'-deoxy, 3',5'-di-O-toluoyl group on the sugar moiety. This modification increases the stability of 4AMDT in serum and enhances its antiviral activity against DNA and RNA viruses. It also inhibits the proliferation of cancer cells and induces cell death by inhibiting protein synthesis.</p>Formule :C29H29N5O6Degré de pureté :Min. 95%Masse moléculaire :543.57 g/mol2'-Deoxy-5-hydroxyuridine 5'-triphosphate
CAS :<p>2'-Deoxy-5-hydroxyuridine 5'-triphosphate (doxorubicin) is a cytotoxic and chemotherapeutic agent that interferes with DNA replication. It is an oxidized form of the natural pyrimidine base thymine. The drug blocks DNA synthesis by preventing the incorporation of uracil into the newly synthesized strand, which causes strand breaks. Doxorubicin has been shown to be effective in treating a variety of cancers, including those of the breast, ovaries, bladder, and stomach. This drug can also cause severe side effects such as heart damage and hearing loss due to its interaction with cellular oxygen metabolism.</p>Degré de pureté :Min. 95%6-Chloro-9-(3',5'-di-O-benzoyl-2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)purine
CAS :<p>6-Chloro-9-(3',5'-di-O-benzoyl-2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a nucleoside that is used as an anticancer and antiviral agent. It is synthesized from 9-(3',5'-di-O-benzoyl)-2'-deoxyribofuranosyl chloride, which is then chlorinated to form 6-chloro purine. This product has been shown to be active against human DNA tumor cells and other viruses in vitro. 6CPA, like other nucleosides, can be phosphorylated on the 3' or 5' position of the sugar moiety, yielding monophosphate or diphosphate derivatives respectively. The monophosphate derivative of 6CPA has a higher cytotoxicity than the diphosphate derivative. The deoxyribose sugar moiety can</p>Formule :C24H18CIFN4O5Degré de pureté :Min. 95%Masse moléculaire :496.89 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine
CAS :<p>4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine is a novel nucleoside analog that can be activated to the monophosphate form for incorporation into DNA. It has antiviral and anticancer properties. 4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine has been shown to inhibit the proliferation of cultured tumor cells, suggesting a potential use in cancer chemotherapy.</p>Formule :C9H10FN5O5Degré de pureté :Min. 95%Masse moléculaire :287.2 g/mol5-Azido- 2'- deoxycytidine
CAS :<p>5-Azido-2'-deoxycytidine is a high purity, novel, modified, and synthesized nucleoside with anticancer and antiviral properties. It is a diphosphate that is used in the synthesis of DNA as an activator. 5-Azido-2'-deoxycytidine has been shown to inhibit the growth of cancer cells and to be active against influenza virus.</p>Formule :C9H12N6O4Degré de pureté :Min. 95%Masse moléculaire :268.23 g/mol5'-O-DMT-thymidine phosphoramidite dimer
<p>5'-O-DMT-thymidine phosphoramidite dimer is a novel, synthetic nucleoside that can be used for the treatment of cancers. It is an antiviral and antibacterial agent that has been shown to have cytotoxic effects against cancer cells. 5'-O-DMT-thymidine phosphoramidite dimer is not active against bacteria or viruses that are resistant to other nucleoside analogues. This compound inhibits DNA synthesis by inhibiting the activity of DNA polymerase, which is required for the replication of DNA. The chemical structure of 5'-O-DMT-thymidine phosphoramidite dimer resembles thymidine monophosphate, but it has a different sugar group at the 5' position and contains two phosphate groups at the 3' position.</p>Degré de pureté :Min. 95%3'-Azido-3'-deoxy-5-methylcytidine
CAS :<p>3'-Azido-3'-deoxy-5-methylcytidine (AZDMC) is a novel nucleoside analog that inhibits viral replication. AZDMC is an activator of cellular DNA synthesis, which is essential for the replication of DNA and the production of RNA. It also has antiviral activity against influenza A and B viruses. The chemical name for AZDMC is 3'-azido-3'-deoxy-5-methylcytidine monophosphate (AMP). The CAS number for AZDMC is 1282040-14-5. It can be synthesized with high purity and quality by Ribonucleosides, Modified, Deoxyribonucleosides, Nucleosides, Phosphoramidites.</p>Degré de pureté :Min. 95%N6-Benzoyl-3'-deoxyadenosine
CAS :<p>N6-Benzoyl-3'-deoxyadenosine is a nucleoside analogue that is used as a substrate for DNA polymerase. The efficiency of this compound has been shown to be higher than other nucleotides. In addition, N6-Benzoyl-3'-deoxyadenosine has been shown to be an efficient donor in the ligation reaction and can also act as a competitive inhibitor of topoisomerase II. N6-Benzoyl-3'-deoxyadenosine is a scissile substrate for DNA topoisomerase II and cleaves at the same site as dATP. This compound has been shown to be active against both Gram-positive bacteria and Mycobacterium tuberculosis with high selectivity.</p>Formule :C17H17N5O4Degré de pureté :Min. 95%Masse moléculaire :355.35 g/mol5-Fluorescein dT phosphoramidite
<p>5-Fluorescein dT phosphoramidite is a novel modified nucleoside that has antiviral, activator, and anticancer properties. It is an analog of fluorouracil with a 5-fluorescein group at the 5' position. This phosphoramidite is synthesized from 2',3'-dideoxyuridine 5'-triphosphate and fluorescein diphosphate. It can be used to bind to DNA and inhibit viral replication. Other anticancer effects may be due to its ability to activate DNA synthesis by binding to deoxyribonucleosides or ribonucleosides in DNA.<br>5-Fluorescein dT phosphoramidite has high purity and quality, making it suitable for use in nucleotide sequencing, mutagenesis studies, and other applications requiring high purity nucleosides.</p>Degré de pureté :Min. 95%5'-O-DMT-thymidine-3'-succinyl CPG 1400 Å
<p>5'-O-DMT-thymidine-3'-succinyl CPG 1400 Å is a nucleoside analog that has been shown to be an effective anticancer agent. It has been shown to activate the cellular DNA synthesis by stimulating the phosphorylation of RNA polymerase II, which is involved in the transcription of DNA. 5'-O-DMT-thymidine-3'-succinyl CPG 1400 Å also inhibits viral replication and may be effective against AIDS. This nucleoside analog induces antiviral effects by inhibiting the synthesis of viral dsDNA.</p>Degré de pureté :Min. 95%2'-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine
CAS :<p>2'-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine (FdA) is a synthetic nucleoside that was designed for use as a dietary supplement to inhibit carcinogenesis. It is an analog of guanosine and is phosphorylated by cellular kinases to form 2'-deoxy-8-(9H-fluoren-2-ylamino)-inosine monophosphate. FdA inhibits the process of DNA replication in mammalian cells, which may be due to its ability to bind single stranded DNA. This drug has been shown to reduce the mutation frequency and increase the life span of mice with bladder cancer.</p>Formule :C23H22N6O4Degré de pureté :Min. 95%Masse moléculaire :446.46 g/mol6-(4-Iodobenzyl)-1-Methyl Pyrimidine-2,4-(1H,3H)-Dione
CAS :<p>6-(4-Iodobenzyl)-1-Methyl Pyrimidine-2,4-(1H,3H)-Dione is a nucleoside analog that has shown to be an activator of the ribonucleotide reductase enzyme. It has also been shown to have anticancer activity. 6-(4-Iodobenzyl)-1-Methyl Pyrimidine-2,4-(1H,3H)-Dione inhibits DNA synthesis by binding to the DNA molecule at the site of incorporation and preventing its duplication. This compound also inhibits RNA synthesis by binding to the RNA molecule at the site of incorporation and preventing its duplication. It has been shown to inhibit cancer cell growth in culture and can be used as a chemotherapeutic agent.</p>Formule :C12H11IN2O2Degré de pureté :Min. 95%Masse moléculaire :342.13 g/mol5-Chloro-5'-deoxycytidine
CAS :<p>5-Chloro-5'-deoxycytidine is a nucleoside with antiviral activity. It is used for the synthesis of phosphoramidites, which are used in DNA and RNA synthesis. 5-Chloro-5'-deoxycytidine has been shown to be an effective activator for novel DNA and RNA analogues, such as phosphorothioates, phosphotriesters, and phosphorodithioates. This compound is also widely used in the preparation of oligodeoxynucleotide analogues that are modified chemically or structurally to improve their biological properties. 5-Chloro-5'-deoxycytidine has been synthesized by modifying the nucleobase with a 5-chloro group at the 5' position on the ribose ring, making it more resistant to degradation by enzymes than other cytosine derivatives.</p>Formule :C9H12ClN3O4Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :261.67 g/molDihydrozeatin riboside-5'-monophosphate sodium salt
CAS :<p>Dihydrozeatin riboside-5'-monophosphate sodium salt is a cytokinin that belongs to the group of indole compounds. It has been shown to inhibit the biosynthesis of ethylene, which prevents fruit from ripening. Dihydrozeatin riboside-5'-monophosphate sodium salt is also able to inhibit the synthesis of adenosine, another plant hormone that inhibits growth and promotes dormancy in plants. The bioassay for this product has been done with amanita muscaria, an edible mushroom found in North America and Europe. This mushroom contains dihydrozeatin as well as other related compounds such as zeatin, which can be converted into dihydrozeatin by enzymes present in the intestines. The symptoms of poisoning by this mushroom include vomiting and diarrhea, owing to its effects on intestinal motility.</p>Formule :C15H22N5Na2O8P·H2ODegré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :495.33 g/mol7-Deaza-2'-deoxy-5'-O-DMT-xanthosine
CAS :<p>7-Deaza-2'-deoxy-5'-O-DMTxanthosine is a nucleoside analog with antiviral properties. It is an activator of the phosphoramidites and can be used in the synthesis of high quality, high purity, and novel nucleosides. 7-Deaza-2'-deoxy-5'-O-DMTxanthosine has been shown to inhibit the replication of DNA by forming a covalent bond with the deoxyribose sugar moiety of DNA. This modification prevents the polymerization of DNA, thereby inhibiting viral replication.</p>Formule :C32H31N3O7Degré de pureté :Min. 95%Masse moléculaire :569.6 g/molUridylyl-3'-5'-cytidine ammonium salt
<p>Uridylyl-3'-5'-cytidine ammonium salt is a monophosphate of cytidine. It is an antiviral agent that inhibits the replication of human immunodeficiency virus type 1 (HIV-1). Uridylyl-3'-5'-cytidine ammonium salt is synthesized by the reaction of uridyl 3'-5' -adenosine monophosphate with cytidine. This compound has been shown to be effective in inhibiting the proliferation of cancer cells. Uridylyl-3'-5'-cytidine ammonium salt has shown activity against a variety of cancers, including breast, lung, and colon cancers.</p>Formule :C18H27N6O13PDegré de pureté :Min. 95%Masse moléculaire :566.41 g/molBiotin-11-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS :<p>Biotin-11-uridine-5'-triphosphate, lithium salt (BUP) is a nucleoside analog that has been modified to allow the incorporation of BUP into DNA. The modification of BUP with lithium salts allows for the covalent attachment of BUP to DNA. This incorporation of BUP into DNA prevents the polymerase from binding to DNA and thus inhibits replication. Biotin-11-uridine-5'-triphosphate, lithium salt (BUP) has demonstrated anticancer and antiviral activity as well as being novel and high quality.</p>Formule :C28H45N6O18P3S·xLiDegré de pureté :Min. 95%Masse moléculaire :878.67 g/mol8-Oxo-7-thioguanosine
CAS :<p>8-Oxoguanosine monophosphate (8-oxoGMP) is a synthetic nucleoside that is activated by the enzyme thioredoxin reductase and phosphorylated to form 8-oxoGTP. The anticancer activity of 8-oxoGMP is due to its ability to inhibit ribonucleotide reductase, which reduces the production of DNA and RNA in cells. This product has been shown to inhibit HIV replication in vitro and in vivo. It also inhibits viral replication by inhibiting the synthesis of viral nucleic acids such as DNA, RNA, and deoxyribonucleic acid (DNA).</p>Formule :C10H12N4O6SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :316.29 g/mol2'-Ethylfluoro-5-methyluridine
<p>2'-Ethylfluoro-5-methyluridine is a nucleoside analog. It has been modified with an ethyl group at the 2' position of the sugar moiety and a fluoro atom in the 5-position of the uracil base that replaces the methyl group. This modification increases its cellular uptake and antiviral activity. It is being studied as a potential anticancer drug.</p>Degré de pureté :Min. 95%3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine
CAS :<p>3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine is a nucleoside derivative that has antiviral activity. It is synthesized by the condensation of 2,3,5-trihydroxybenzoic acid with 3'-chloro-5'-fluoroacetophenone in the presence of pyridine and triethylamine. The nucleoside has been shown to be an effective inhibitor of HIV replication in vitro. 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine also inhibits DNA synthesis in human lymphocytes at concentrations of 5 μM or less. This compound can be used as an activator for DNA polymerases and phosphoramidites for DNA synthesis.</p>Formule :C23H17Cl2FN2O7Degré de pureté :Min. 95%Masse moléculaire :523.29 g/mol2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å
<p>2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å is a modified nucleoside that is synthesized from 2'-deoxyribonucleosides and succinic anhydride. It has antiviral, anticancer, and antimalarial activities. It can also be used to modify DNA sequences. This product is a novel phosphoramidite monomer with high purity.</p>Degré de pureté :Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite is a modified nucleoside that can be used to synthesize oligonucleotides. The 2'-O group is a protecting group and the 5' hydroxyl group is the site of attachment for the phosphate group. This product is an anticancer, antiviral, and antiretroviral agent. It has been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>Formule :C45H60IN4O9PSiDegré de pureté :Min. 95%Masse moléculaire :986.97 g/mol
