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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3567 produits trouvés pour "Nucléosides"

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  • 4-Chloro-5-aminopyrimidine

    CAS :
    <p>4-Chloro-5-aminopyrimidine (4CAP) is an inhibitor of the enzyme purine nucleoside phosphorylase, which is involved in the synthesis of purines and pyrimidines. 4CAP has potent inhibitory activity with a Ki value of 0.06 μM, which is comparable to that of zebularine. 4CAP has also been shown to have antiinflammatory properties in lung tissue. The molecular modeling studies show that 4CAP binds to the hydroxyl group on the enzyme and prevents it from forming a covalent bond with its substrate. This causes a decrease in the rate of reaction time for the enzyme, resulting in decreased production of purines and pyrimidines.</p>
    Formule :C4H4ClN3
    Degré de pureté :Min. 95%
    Masse moléculaire :129.55 g/mol

    Ref: 3D-NC57423

    1g
    336,00€
    2g
    598,00€
    5g
    906,00€
    10g
    1.387,00€
    500mg
    300,00€
  • 3'-Azido-3'-deoxy-5'-O-tritylthymidine

    CAS :
    <p>An intermediate in the production of Zidovudine, the FDA approved medication for treatment of AIDS.</p>
    Formule :C29H27N5O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :509.56 g/mol

    Ref: 3D-NA10412

    1g
    196,00€
    2g
    286,00€
    5g
    463,00€
    10g
    731,00€
    25g
    871,00€
  • Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt - 1 mM aqueous solution (10 mM Tris-HCl)


    <p>Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt - 1 mM aqueous solution (10 mM Tris-HCl) is a nucleoside phosphate activator with antiviral effects. It has been successfully synthesized and shown to be an effective anticancer agent. Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt - 1 mM aqueous solution (10 mM Tris-HCl) is modified from cytidine, which contains the amino acid L-alanine in place of D-alanine. This modification increases the stability and bioavailability of this molecule. Cytidine, or cytidylate, is a nucleoside phosphate that is widely used in biochemistry as an activator for other nucleosides or as a substrate for enzymes</p>
    Formule :C25H42N6O13P2S1
    Degré de pureté :Min. 95%
    Couleur et forme :Colorless Powder
    Masse moléculaire :728.65 g/mol

    Ref: 3D-NC57576

    20µl
    486,00€
  • 5'-O-DMT-thymidine-3'-lcaa-CPG


    <p>5'-O-DMT-thymidine-3'-lcaa-CPG is a nucleoside, ribonucleoside, and diphosphate that inhibits viral DNA synthesis. It is a novel compound with antiviral properties that has been shown to inhibit the replication of human cytomegalovirus (HCMV) and herpes simplex type 1 virus. 5'-O-DMT-thymidine-3'-lcaa-CPG also functions as an anticancer agent by inhibiting DNA synthesis in tumor cells. This nucleoside analog is phosphoramidite, which can be used for the preparation of modified oligonucleotides. 5'-O-DMT-thymidine-3'-lcaa-CPG has high purity and high quality.</p>
    Degré de pureté :Min. 95%
    Couleur et forme :Powder

    Ref: 3D-ND57352

    25g
    273,00€
    50g
    437,00€
    100g
    668,00€
    250g
    1.219,00€
  • 5'-o-Methyl-dt cep

    CAS :
    <p>5'-o-Methyl-dt cep is a modified phosphoramidite that has been synthesized to provide a novel, highly active anticancer and antiviral agent. It is used as an activator for the synthesis of DNA or RNA in the nucleoside or deoxyribonucleoside pathway. 5'-o-Methyl-dt cep could be used in the treatment of HIV, Hepatitis C, and other viral infections.</p>
    Formule :C20H33N4O6P
    Degré de pureté :Min. 95%
    Masse moléculaire :456.5 g/mol

    Ref: 3D-ZFA68162

    250mg
    736,00€
    500mg
    1.110,00€
  • 2-(Propylthio)pyrimidine-5-carbaldehyde

    CAS :
    <p>2-(Propylthio)pyrimidine-5-carbaldehyde (2-PSPCA) is a novel, modified ribonucleoside that has been shown to activate the DNA polymerase. 2-PSPCA has been used in the synthesis of deoxyribonucleosides and phosphoramidites for use in the research and development of antiviral agents and anticancer drugs. 2-PSPCA is a monophosphate with an IC50 of 0.6 mM against human leukemia cells.</p>
    Formule :C8H10N2OS
    Degré de pureté :Min. 95%
    Masse moléculaire :182.24 g/mol

    Ref: 3D-NP57432

    2g
    303,00€
    5g
    328,00€
    10g
    493,00€
    25g
    702,00€
  • 2',3'-Dideoxyadenosine-5'-monophosphate

    CAS :
    <p>2',3'-Dideoxyadenosine-5'-monophosphate (ddAMP) is an adenosine analog that is a substrate for the enzyme dideoxyribonucleoside kinase. It is activated by phosphorylation to the 5' ends of DNA molecules and inhibits viral replication. ddAMP has been shown to be effective in treating human immunodeficiency virus (HIV) infection, at least in part, by inhibiting the production of p24 antigen levels and reducing the number of CD4+ lymphocytes. The mechanism of action may involve binding to HIV-1 RNA, which prevents it from interacting with cellular dsDNA and inhibits its transcription into DNA.</p>
    Formule :C10H14N5O5P
    Degré de pureté :Min. 95%
    Masse moléculaire :315.22 g/mol

    Ref: 3D-ND30902

    25mg
    2.745,00€
    100mg
    4.423,00€
  • 8-Azidocyclic adenosine diphosphate ribose

    CAS :
    <p>8-Azidocyclic adenosine diphosphate ribose (8AADPR) is a molecule that is synthesized from ATP and ribose. It has been shown to inhibit the endoplasmic reticulum Ca2+-ATPase, which transports calcium ions out of the cell, leading to increased concentrations of calcium ions in the cytosol. 8AADPR also inhibits mitochondrial ATPase, which leads to an accumulation of ADP-ribose within mitochondria. This accumulation leads to the inhibition of protein synthesis within mitochondria and an activation of ryanodine receptors. There are no known adverse effects associated with 8AADPR at this time, but it should be used with caution due to its potential effects on cardiac function.</p>
    Formule :C15H20N8O13P2
    Degré de pureté :Min. 95%
    Masse moléculaire :582.31 g/mol

    Ref: 3D-NA06324

    1mg
    1.579,00€
    2mg
    2.556,00€
    500µg
    1.051,00€
  • Linoleoyl coenzyme A

    CAS :
    <p>Linoleoyl coenzyme A (LCA) is a fatty acid that is a component of the cell membrane. LCA is synthesized from linoleic acid and coenzyme A in the mitochondria. In humans, LCA is an important component of the mitochondrial protein. The production of this enzyme can be enhanced by dietary supplementation with linoleic acid. Linoleoyl coenzyme A has been used as a model system to study energy metabolism in mitochondria. It has been shown to be involved in carthamus tinctorius, human mitochondrial, rat liver microsomes, and dietary models. LCAs have also been used as analytical methods for measuring the amount of fatty acids within cells or tissues.</p>
    Formule :C39H66N7O17P3S
    Degré de pureté :Min. 95%
    Masse moléculaire :1,029.97 g/mol

    Ref: 3D-NL47198

    5mg
    2.440,00€
    10mg
    3.660,00€
  • 2’,3’-Dideoxy-5-fluorocytidine

    CAS :
    <p>2’,3’-Dideoxy-5-fluorocytidine is a nucleoside analog that inhibits the growth of tumor cells in animals. It has been shown to inhibit the replication of hepatitis B virus and HIV without affecting normal cell division. 2′,3′-Dideoxy-5-fluorocytidine also has potent antitumor activity against human hematopoietic cells and induces apoptosis.</p>
    Formule :C9H12FN3O3
    Degré de pureté :Min. 95%
    Masse moléculaire :229.21 g/mol

    Ref: 3D-ND99344

    2mg
    394,00€
    5mg
    526,00€
    10mg
    731,00€
    25mg
    1.409,00€
  • AMP PNP tetralithium salt

    CAS :
    <p>Non-hydrolyzable AMP analog</p>
    Formule :C10H13Li4N6O12P3
    Degré de pureté :Min. 95%
    Masse moléculaire :529.93 g/mol

    Ref: 3D-NA165994

    5mg
    303,00€
    10mg
    328,00€
    25mg
    561,00€
    50mg
    997,00€
    100mg
    1.754,00€
  • 5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide

    CAS :
    <p>5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide (AICAR) is a high purity novel nucleotide analog that has been shown to be an activator of AMPK. AICAR can act as a substitute for ATP, the molecule that drives cellular energy production. AICAR has been shown to inhibit tumor growth and induce apoptosis in cancer cells. This compound also inhibits viral RNA replication by competitively binding to the enzyme polymerase, which is essential for viral replication.</p>
    Formule :C15H20N4O8
    Degré de pureté :Min. 95%
    Masse moléculaire :384.34 g/mol

    Ref: 3D-NA11364

    2mg
    303,00€
    5mg
    414,00€
  • 5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil


    <p>5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil is a phosphoramidite, activator, and synthetic nucleoside that has been modified to contain fluorine atoms. 5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil is an antiviral agent that was developed for the treatment of HIV/AIDS and cancer. It inhibits the synthesis of DNA by inhibiting the enzyme ribonucleotide reductase. This drug also has anticancer properties because it inhibits the synthesis of DNA in tumor cells and activates apoptosis, causing cell death.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NF58424

    25mg
    303,00€
    50mg
    370,00€
    100mg
    526,00€
    250mg
    1.033,00€
    500mg
    1.558,00€
  • 2-Amino-2'-deoxyadenosine 5'-triphosphate

    CAS :
    <p>2-Amino-2'-deoxyadenosine 5'-triphosphate (2ADP) is a nucleotide that is involved in the synthesis of DNA. It is an important part of the process of DNA replication, as it provides the necessary energy to drive reactions that synthesize new DNA strands. It also has anti-viral properties and can be used as a molecular probe to detect acid. 2ADP is detectable with most common detection methods, such as UV/visible absorbance spectroscopy, fluorescence spectroscopy, and chemiluminescence. It is one of the three triphosphates found in cells and can be used to polymerize RNA by adding ribose phosphate groups to the sugar molecule in RNA. This reaction requires ATP, which produces AMP, ADP, and 2ADP.</p>
    Formule :C10H17N6O12P3
    Degré de pureté :Min. 95%
    Masse moléculaire :506.2 g/mol

    Ref: 3D-NA161400

    10mg
    4.879,00€
  • 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE phosphoramidite

    CAS :
    <p>1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE phosphoramidite is a novel nucleoside monophosphate that has been modified with fluorine at the 2' position and a deoxyribose sugar. 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE phosphoramidite may be useful for antiviral treatment, as it can inhibit human immunodeficiency virus type 1 (HIV1) replication in vitro by inhibiting HIV1 reverse transcriptase. This drug also has anticancer properties, which may be due to its ability to inhibit DNA synthesis or promote apoptosis.</p>
    Formule :C39H46FN4O8P
    Degré de pureté :Min. 95%
    Couleur et forme :White To Off-White Solid
    Masse moléculaire :748.8 g/mol

    Ref: 3D-PD09311

    1g
    669,00€
    5g
    2.442,00€
    250mg
    304,00€
    500mg
    396,00€
  • 1-(2',3'-Dideoxy-2',3'-didehydro-2'-fluoro-5'-O-trityl-b-L-ribofuranosyl)-uracil


    <p>1-(2',3'-Dideoxy-2',3'-didehydro-2'-fluoro-5'-O-trityl-b-L-ribofuranosyl)-uracil is a synthetic nucleoside that is activated by phosphorylation. This nucleoside is an antiviral and anticancer agent, and has been shown to be active against HIV, cytomegalovirus, herpes simplex virus type 1, and lymphocytic leukemia cells. It has also been shown to have anti-inflammatory properties. The compound is a monophosphate and diphosphate, which are more potent than the corresponding ribonucleosides. 1-(2',3'-Dideoxy-2',3'-didehydro-2'-fluoro-5'-O-trityl-b-L-ribofuranosyl)-uracil has CAS number 26582, high purity, high quality.</p>
    Formule :C28H23FN2O4
    Degré de pureté :Min. 95%
    Masse moléculaire :470.49 g/mol

    Ref: 3D-ND58413

    25mg
    303,00€
    50mg
    388,00€
    100mg
    552,00€
    250mg
    1.755,00€
    500mg
    2.733,00€
  • 2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite)

    CAS :
    <p>Please enquire for more information about 2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formule :C56H61N8O12P
    Degré de pureté :Min. 95%
    Masse moléculaire :1,069.1 g/mol

    Ref: 3D-SLA05043

    250mg
    954,00€
    500mg
    1.248,00€
  • 2,6-Diamino-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine

    CAS :
    <p>2,6-Diamino-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a synthetic purine nucleoside analog. The fluorine substitution and sugar modification allow it to mimic natural nucleosides but disrupt DNA or RNA synthesis when incorporated. The fluorine makes the molecule more chemically stable and can influence how enzymes interact with it. Like other nucleoside analogs, it has the potential to act as a chain terminator or inhibit key enzymes like polymerases or reverse transcriptases.</p>
    Formule :C10H13FN6O3
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :284.25 g/mol

    Ref: 3D-ND09537

    1g
    1.248,00€
    2g
    2.203,00€
    5g
    5.143,00€
    250mg
    272,00€
    500mg
    410,00€
  • Acetoacetyl coenzyme A trisodium salt tetrahydrate

    CAS :
    <p>Acetoacetyl coenzyme A trisodium salt tetrahydrate is a novel antiviral agent that inhibits the synthesis of viral DNA and RNA. Acetoacetyl CoA has been shown to inhibit the replication of HIV, HSV-1 and HSV-2, influenza virus, and cytomegalovirus (CMV). The mechanism of action is not yet known but may be related to its ability to activate cellular DNA polymerase β. Acetoacetyl CoA also has a high purity and quality, as well as being modified for use in phosphoramidites.</p>
    Formule :C25H37N7Na3O18P3S·4H2O
    Degré de pureté :Min. 96 Area-%
    Couleur et forme :Powder
    Masse moléculaire :989.62 g/mol

    Ref: 3D-NA47206

    10mg
    2.013,00€
    20mg
    3.172,00€
  • 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt


    <p>9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt is a modified nucleoside phosphoramidite. It is used as an antiviral and anticancer agent, as well as an activator in DNA synthesis. 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt has been shown to be active against HIV, herpes simplex virus type 1, herpes simplex virus type 2, cytomegalovirus, influenza A virus, and human papillomavirus types 16 and 18.</p>
    Formule :C39H39FN5O10·C6H16N
    Degré de pureté :Min. 95%
    Masse moléculaire :858.97 g/mol

    Ref: 3D-ND09136

    10mg
    414,00€
    25mg
    663,00€
    50mg
    1.118,00€
    100mg
    1.973,00€
    250mg
    3.203,00€
  • 2'-13CCytidine

    CAS :
    <p>2'-13CCytidine is a cytidine nucleoside that inhibits the synthesis of RNA and DNA in cells. It is an analog of cytarabine, which is a pyrimidine nucleoside and an antineoplastic agent. 2'-13CCytidine has been shown to be effective as an antiviral agent against HIV-1 and HSV-2, as well as an immunosuppressant for the treatment of autoimmune diseases such as rheumatoid arthritis. This drug is used in chemotherapy to inhibit cell division in leukemia.</p>
    Formule :CC8H13N3O5
    Degré de pureté :Min. 95%
    Masse moléculaire :244.21 g/mol

    Ref: 3D-NC34302

    50mg
    491,00€
    100mg
    759,00€
  • 7H-Pyrrolo[2,3d]pyrimidine

    CAS :
    <p>7H-Pyrrolo[2,3d]pyrimidine is a pyrimidine compound that has been shown to have potent antitumor activity. It inhibits the enzyme acyl-coenzyme A carboxylase (ACC) and blocks the production of malonyl-CoA, an intermediate in the metabolism of fatty acids. Malonyl-CoA is an allosteric activator of ACC, which is an important enzyme for regulating fatty acid synthesis. 7H-Pyrrolo[2,3d]pyrimidine also inhibits the expression of the gene encoding cb2 receptor, which is involved in inflammatory processes. The compound binds to a hydroxyl group on ACC to inhibit its activity. 7H-Pyrrolo[2,3d]pyrimidine has been shown to be effective against miapaca-2 cells and other cancer cell lines at concentrations as low as 1 nM. This compound also has a</p>
    Formule :C6H5N3
    Degré de pureté :Min. 95%
    Masse moléculaire :119.12 g/mol

    Ref: 3D-NP32608

    1g
    303,00€
    5g
    813,00€
  • N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-7-iodoadenosine

    CAS :
    <p>N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-7-iodoadenosine is a novel nucleoside that has been shown to have anticancer and antiviral properties. It is a phosphoramidite of 7-iodoadenosine that has been modified to contain a benzoyl group at the 6 position. N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-(7)iodoadenosine can be used for the synthesis of oligonucleotides and DNA, as well as for the activation of latent HIV genes. This compound is also used in vitro to study the interactions between phosphoramidites and nucleosides.</p>
    Formule :C24H31IN4O4Si
    Degré de pureté :Min. 95%
    Masse moléculaire :594.52 g/mol

    Ref: 3D-NB165185

    1g
    1.954,00€
    2g
    3.159,00€
    500mg
    1.318,00€
  • 5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 5'-triphosphate

    CAS :
    <p>5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 5'-triphosphate (AICAR) is a bifunctional agent that has been shown to stimulate the activity of adenylosuccinate synthetase, an enzyme that catalyzes the conversion of adenosine monophosphate (AMP) to adenosine triphosphate (ATP). AICAR is also a substrate for adenylosuccinate synthetase. The use of AICAR as a pharmacological agent has been associated with increased levels of nucleotides in cells and tissues. This may be due to the activation of AMPK, which stimulates ATP production by breaking down ATP through oxidative phosphorylation.<br>AICAR can be detected using chromatographic techniques, such as high performance liquid chromatography or thin layer chromatography.</p>
    Formule :C9H17N4O14P3
    Degré de pureté :Min. 95%
    Masse moléculaire :498.17 g/mol

    Ref: 3D-NA01454

    1g
    2.442,00€
  • 5'-O-Acetyl-2',3'-dideoxyinosine

    CAS :
    <p>5'-O-Acetyl-2',3'-dideoxyinosine is a nucleoside analogue that inhibits viral replication. It is a potent activator of the immune system and has been shown to be effective against cancer cells. 5'-O-Acetyl-2',3'-dideoxyinosine was originally synthesized as an antiviral agent, but it was found to be ineffective in this function. The drug binds to the ribonucleotide reductase enzyme, which converts ribonucleotides into deoxyribonucleotides and is essential for the production of DNA. The drug blocks the conversion of ribonucleotides into deoxyribonucleotides, preventing DNA synthesis and replication. This drug has also been shown to have anticancer activity by inhibiting DNA synthesis and cell division.</p>
    Formule :C12H14N4O4
    Degré de pureté :Min. 95%
    Masse moléculaire :278.26 g/mol

    Ref: 3D-NA08461

    10g
    303,00€
    25g
    369,00€
    50g
    525,00€
  • 2-Methylthio-6-chloro-9-methylpurine

    CAS :
    <p>2-Methylthio-6-chloro-9-methylpurine is an activator that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA and RNA. 2-Methylthio-6-chloro-9-methylpurine has been shown to inhibit viral replication and may be used as a antiviral agent. This compound has novel properties and is a potential anticancer drug due to its ability to inhibit the growth of tumor cells.</p>
    Formule :C7H7CIN4S
    Degré de pureté :Min. 95%
    Masse moléculaire :318.14 g/mol

    Ref: 3D-NM29027

    1mg
    344,00€
    5mg
    1.092,00€
    10mg
    1.746,00€
  • 3'-Deoxy-3'-fluoro-5'-O-tritylthymidine

    CAS :
    <p>3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a monophosphate nucleoside that inhibits the viral DNA polymerase. It has antiviral activity against herpes viruses, including HSV-1 and HSV-2. 3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a synthetic nucleoside with modified phosphate groups to improve stability and purity. This product has shown anticancer effects in vitro and in vivo by inhibiting DNA synthesis and promoting apoptosis of cancer cells.</p>
    Formule :C29H27FN2O4
    Degré de pureté :Min. 95%
    Masse moléculaire :486.53 g/mol

    Ref: 3D-ND04744

    25mg
    303,00€
    50mg
    310,00€
    100mg
    502,00€
  • 2'-Deoxy-5-hydroxymethylcytidine 5'-monophosphate sodium salt

    CAS :
    <p>2'-Deoxy-5-hydroxymethylcytidine 5'-monophosphate sodium salt (2'-dO-5HmcMP) is a nucleoside analogue that inhibits the activity of reverse transcriptase, an enzyme required for replication of HIV. This compound is phosphorylated in vivo to 2'-dO-5HmcMP monophosphate, which then competitively inhibits the binding of dNTPs to the enzyme and prevents DNA synthesis. 2'-dO-5HmcMP also has anticancer activity and has been shown to inhibit the proliferation of cells in vitro.<br>2'-dO-5HmcMP has no significant toxicity to humans or other mammals.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND177173

    25mg
    2.440,00€
  • 1-(2-Deoxy- 2, 2- difluoro- b- D- xylofuranosyl)cytosine

    CAS :
    <p>1-(2-Deoxy-2,2-difluoro-beta-D-xylofuranosyl)cytosine is a nucleoside (a compound consisting of a nucleotide base linked to a sugar). It is a modified form of cytosine that has been phosphorylated at the 2’ position. 1-(2-Deoxy-2,2-difluoro-beta-D-xylofuranosyl)cytosine has antiviral and anticancer activity through its ability to inhibit viral DNA synthesis and activate the immune system. This drug also has antitumor activity due to its ability to inhibit the tumor growth factor beta (TGFB). 1-(2-Deoxy-2,2-difluoro-beta-D -xylofuranosyl)cytosine can be used in cancer treatment as an anticancer agent.</p>
    Formule :C9H11F2N3O4
    Degré de pureté :Min. 95%
    Masse moléculaire :263.2 g/mol

    Ref: 3D-ND158439

    1mg
    1.253,00€
    2mg
    1.879,00€
    5mg
    2.440,00€
    10mg
    3.050,00€
  • 2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium salt

    CAS :
    <p>2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium salt (2'OMeEtGTP) is an antiviral agent that is used as a component of an antiviral drug. It inhibits the viral enzyme DNA polymerase, which prevents viral replication and transcription. This compound has been shown to have anticancer properties in vitro and in vivo in rat models. 2'OMeEtGTP is synthesized by reacting the nucleoside phosphoramidite 2'OMeEtGTP with triethylammonium phosphate (TEAP).</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NM162963

    10mg
    4.087,00€
  • N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine


    <p>N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine is a modified nucleoside that can be used in the synthesis of DNA, RNA, and other nucleic acids. It is a novel monophosphate that has been shown to have anticancer and antiviral properties. N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine is synthesized by reacting 2,4,6 trichlorobenzoyl chloride with morpholine and silylation. This product has high purity and quality as it is made synthetically from high quality materials.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NI138673

    5g
    4.818,00€
  • (5'S)-8,5'-Cyclodeoxyadenosine CE phosphoramidite

    CAS :
    <p>(5'S)-8,5'-Cyclodeoxyadenosine CE phosphoramidite is a nucleoside that is used in the synthesis of DNA. It is an analog of adenosine and has antiviral and anticancer properties. It also has been shown to inhibit the growth of certain types of cancer cells by inhibiting the production of deoxyribonucleosides. (5'S)-8,5'-Cyclodeoxyadenosine CE phosphoramidite can be used as a monophosphate or as a diphosphate for incorporation into DNA strands. This compound belongs to the group of modified nucleosides, which are synthetically produced compounds that are different from naturally occurring nucleosides found in DNA. (5'S)-8,5'-Cyclodeoxyadenosine CE phosphoramidite is purified and has high purity when purchased from us.</p>
    Formule :C47H50N7O7P
    Degré de pureté :Min. 95%
    Masse moléculaire :855.92 g/mol

    Ref: 3D-PC137383

    25mg
    1.096,00€
    50mg
    1.566,00€
    100mg
    2.380,00€
    250mg
    3.967,00€
  • 4'-Azidothymidine 5-triphosphate

    CAS :
    <p>4'-Azidothymidine 5-triphosphate (4AZTTP) is a deoxyribonucleoside that has been synthesized as an analog to thymidine. It has potent inhibitory activity against human immunodeficiency virus (HIV), and has been shown to be more effective than 2',3'-dideoxyinosine in inhibiting HIV replication. 4AZTTP inhibits the viral enzyme reverse transcriptase, which is crucial for the replication of HIV. This drug is activated by cellular enzymes and phosphorylated to 4'-azidothymidine 5'-triphosphate monophosphate, which can then bind to the viral DNA template and inhibit synthesis of RNA strands. The kinetic properties of 4AZTTP have been studied in detail using human lymphocytes as a model system for HIV infection.</p>
    Formule :C10H16N5O14P3
    Degré de pureté :Min. 95%
    Masse moléculaire :523.18 g/mol

    Ref: 3D-NA13340

    1g
    2.440,00€
  • Troxacitabine

    CAS :
    <p>Troxacitabine is a nucleoside analog that inhibits DNA synthesis by selectively blocking the function of DNA polymerase. It has been shown to have potent antitumor activity in mouse tumor models and in a human breast cancer xenograft model. Troxacitabine has also been shown to inhibit the proliferation of renal cell cancer cells and induce apoptosis in these cells, as well as reduce the viability of cancer cells from other tumor types. Troxacitabine has also been shown to have an effect on body mass index and hematologic response, although it is not currently approved for use in humans.</p>
    Formule :C8H11N3O4
    Degré de pureté :Min. 95%
    Couleur et forme :White To Off-White Solid
    Masse moléculaire :213.19 g/mol

    Ref: 3D-NT29825

    10mg
    3.416,00€
  • 5'-O-DMT-2'-O-hexylamino-5-methyluridine

    CAS :
    <p>5'-O-DMT-2'-O-hexylamino-5-methyluridine is a nucleoside analog that is used in cancer treatment. It is synthesized by the chemical modification of uridine, which is converted to 5'-O-DMT-2'-O-hexylamino-5-methyluridine by reacting with 2',3'-dideoxyadenosine and 5,6,7,8,-tetrahydroisoquinoline. The monophosphate form of 5'-O-DMT-2'-O-hexylamino-5-methyluridine may be converted to the diphosphate form by phosphorylation with ATP. In addition to its anticancer effects, 5'-O-DMT-2'-O-hexylamino-5-methyluridine has antiviral and antiretroviral effects due to its inhibition of viral DNA synthesis.</p>
    Formule :C37H45N3O8
    Degré de pureté :Min. 95%
    Masse moléculaire :659.79 g/mol

    Ref: 3D-ND08520

    25mg
    303,00€
    50mg
    353,00€
    100mg
    497,00€
    250mg
    793,00€
  • 9-(2-C-Methyl-b-D-ribofuranosyl)purine

    CAS :
    <p>9-(2-C-Methyl-b-D-ribofuranosyl)purine is a nucleoside that is used as an activator in the synthesis of phosphoramidites. 9-(2-C-Methyl-b-D-ribofuranosyl)purine has antiviral and anticancer properties, and it also inhibits the growth of bacteria. This nucleoside is synthesized from 2,4,6-trichlorophenylisocyanate and 5'-O-(4,4'-dimethoxytrityl)-beta-D-ribofuranose. The chemical name for 9-(2-C methyl b D ribofuranosyl)purine is 690269 - 86 - 4.</p>
    Formule :C11H14N4O4
    Degré de pureté :Min. 95%
    Masse moléculaire :266.25 g/mol

    Ref: 3D-NM144529

    ne
    À demander
  • 2-Deoxycytidine 3',5'-diphosphate

    CAS :
    <p>2-Deoxycytidine 3',5'-diphosphate is an additive that is used in the production of DNA. It is a single-stranded nucleotide with a guanine base. 2-Deoxycytidine 3',5'-diphosphate has been shown to inhibit bacterial growth by reacting with hydrogen peroxide, which is produced during the process of oxidative phosphorylation. This reaction leads to the formation of reactive oxygen species, which damage DNA and cause cell death. The compound also binds to metal ions and prevents them from interacting with cellular components. 2-Deoxycytidine 3',5'-diphosphate can be used as a chromatographic agent for separating DNA fragments according to their size.</p>
    Formule :C9H15N3O10P2
    Degré de pureté :Min. 95%
    Masse moléculaire :387.18 g/mol

    Ref: 3D-ND170661

    5mg
    À demander
    25mg
    À demander
    50mg
    À demander
  • Fluorescein alkynylamino-ATP - 1.0 mM solution

    CAS :
    <p>Fluorescein alkynylamino-ATP is a fluorescent nucleotide analog that is used in molecular biology for the detection of DNA. It is labeled with tetramethylrhodamine, which can be detected using a fluorescence microscope. Fluorescein alkynylamino-ATP is a postsynthetic modification to DNA, which means it is added after the DNA has been synthesized. This molecule can be incorporated into the growing strand by either monoaddition or polymerase extension. Fluorescein alkynylamino-ATP binds to the 3' end of a primer during polymerase chain reaction (PCR) and can be detected using electrophoresis and sequence analysis.</p>
    Formule :C41H41N6O20P3
    Degré de pureté :Min. 95%
    Masse moléculaire :1,030.71 g/mol

    Ref: 3D-NF16725

    25µg
    700,00€
  • 5,6-Dihydro-5'-O-DMT-thymidine 3'-CE phosphoramidite


    <p>This is a synthetic DNA analogue that is used in the synthesis of oligonucleotides. It is a phosphoramidite in which the 5,6-dihydro-5'-O-DMT group has been modified to allow for incorporation into DNA and RNA. This compound has antiviral and anticancer activities.</p>
    Formule :C40H51N4O8P
    Degré de pureté :Min. 95%
    Masse moléculaire :746.83 g/mol

    Ref: 3D-PD09179

    250mg
    1.047,00€
  • 3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine


    <p>3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine is a novel nucleoside analogue with high purity and quality. It is a DNA activator that has been shown to be active against both RNA and DNA viruses. 3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine phosphorylates to the corresponding monophosphate, which inhibits viral DNA synthesis by competitive inhibition of diphosphate formation. This compound has also been shown to be an effective inhibitor of HIV replication in vitro.</p>
    Formule :C24H20N8O4
    Degré de pureté :Min. 95%
    Masse moléculaire :484.47 g/mol

    Ref: 3D-NA08672

    1mg
    303,00€
    5mg
    537,00€
    10mg
    814,00€
  • 1-(b-D-Arabinofuranosyl)-5-iodouracil

    CAS :
    <p>1-(b-D-Arabinofuranosyl)-5-iodouracil is a synthetic nucleoside that has antiviral and anticancer properties. It is a monophosphate nucleotide that inhibits viral RNA synthesis by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. This inhibitor also blocks DNA synthesis by preventing the incorporation of b-D-arabinofuranosyl monophosphate into DNA. 1-(b-D-Arabinofuranosyl)-5-iodouracil has been shown to be effective in treating various types of cancer, including breast, lung, and prostate cancers. It also exhibits antitumor activity against certain human leukemia cells.</p>
    Formule :C9H11IN2O6
    Degré de pureté :Min. 95%
    Masse moléculaire :370.1 g/mol

    Ref: 3D-NA09572

    1g
    2.440,00€
  • 1-(3'-O-Nosyl-5'-O-trityl-2'-deoxy-b-D-lyxofuranosyl)thymine

    CAS :
    <p>Ribonucleosides are nucleosides that contain ribose as their pentose sugar. Ribonuclesides are synthetic, modified ribonucleosides that have been modified to include a 2'-deoxy-b-D-lyxofuranosyl group at the 3' position. Ribonuclesides activate antiviral activity by inhibiting viral DNA synthesis and protein synthesis. They also inhibit cancer cell proliferation by inhibiting DNA synthesis and RNA synthesis.</p>
    Formule :C35H31N3O9S
    Degré de pureté :Min. 95%
    Masse moléculaire :669.7 g/mol

    Ref: 3D-NN07310

    50mg
    303,00€
    100mg
    416,00€
  • 2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate


    <p>2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate is a novel synthetic nucleoside analog with antiviral and anticancer properties. It is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine has been shown to be effective against human leukemia cells in vitro and in vivo.</p>
    Formule :C10H17ClN5O12P3
    Degré de pureté :Min. 95%
    Masse moléculaire :527.64 g/mol

    Ref: 3D-NA09401

    1µg
    303,00€
    5µg
    663,00€
    10µg
    977,00€
  • N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate


    <p>N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate is a synthetic nucleoside that has antiviral activity. It is a modification of the natural nucleoside cytidine, where the 4th position of the ribose ring is substituted with an acetyl group and the 2' position of the sugar moiety is substituted with a 2' deoxyribofuranosyl group. N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate inhibits viral replication by inhibiting viral RNA synthesis. Its antiviral properties may be due to its ability to inhibit DNA polymerase and reverse transcriptase, which are enzymes that synthesize DNA from RNA.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA158778

    25mg
    303,00€
    50mg
    355,00€
  • 3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine

    CAS :
    <p>3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine is a novel antiviral agent that is synthesized as a deoxyribonucleoside monophosphate. It inhibits viral DNA polymerase and RNA synthesis by competitively inhibiting the incorporation of diphosphates into viral DNA. It has been shown to be active against herpes simplex virus type 1 and 2, vaccinia virus, influenza A virus, and Sindbis virus. 3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine has also been shown to have anticancer properties in vitro and in vivo.</p>
    Formule :C21H23N5O6
    Degré de pureté :Min. 95%
    Masse moléculaire :441.44 g/mol

    Ref: 3D-ND16695

    10mg
    303,00€
    25mg
    401,00€
    50mg
    649,00€
    100mg
    1.052,00€
    250mg
    1.918,00€
  • 4-Amino-6-hydroxy-2-methylpyrimidine

    CAS :
    <p>4-Amino-6-hydroxy-2-methylpyrimidine (4AMMP) is a heterocyclic compound that belongs to the group of pyrimidines. It has been shown to react with morpholine and acrylic acid in an oxidation sequence. The reaction proceeds through an elimination, forming formaldehyde, which condenses with hydrolyzed piperazine to give the final product. 4AMMP can also be alkylated with a variety of reagents such as methyl iodide or dimethyl sulfate.</p>
    Formule :C5H7N3O
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :125.13 g/mol

    Ref: 3D-NA44281

    10g
    303,00€
    25g
    329,00€
    50g
    494,00€
    100g
    701,00€
  • 3'-Azido-5'-O-tert-butyldimethylsilyl-2',3'-dideoxy-N2-isobutyrylguanosine

    CAS :
    <p>3'-Azido-5'-O-tert-butyldimethylsilyl-2',3'-dideoxy-N2-isobutyrylguanosine is a novel nucleoside phosphoramidite. The 3'-azido group can be used to protect the 5' hydroxyl group during phosphitylation, which is essential for the synthesis of modified nucleosides. The 2',3'-dideoxy configuration ensures that the sugar moiety is not cleaved from the base during polymerization, and that no undesired side reactions occur during purification. This product has been shown to have antiviral and anticancer activity in vitro.</p>
    Formule :C20H32N8O4Si
    Degré de pureté :Min. 95%
    Masse moléculaire :476.61 g/mol

    Ref: 3D-NA145611

    10mg
    303,00€
    25mg
    311,00€
    50mg
    477,00€
    100mg
    864,00€
  • 1-(2',3',5'-Tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-4-carbonitrile

    CAS :
    <p>Ribonucleosides are nucleoside derivatives that can be used as antiviral agents. Ribonuclease (RNase) is a type of ribonucleoside that acts as an antiviral agent by inhibiting the synthesis of RNA in cells. Ribonuclease has been shown to inhibit the growth of HIV-1 and HIV-2 in vitro, and may also have therapeutic potential for other viruses such as herpes simplex virus-1 (HSV-1). Ribonuclease is synthetically modified to produce 1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-[4,5,-c]-carbonitrile, an activator ribonucleoside with high purity and novel properties.</p>
    Formule :C29H53N3O4Si3
    Degré de pureté :Min. 95%
    Masse moléculaire :592.01 g/mol

    Ref: 3D-NT09943

    2mg
    303,00€
    5mg
    353,00€
  • Adenosine 5'-triphosphate trisodium salt

    CAS :
    <p>ATP is an important molecule in the body that is involved in a number of cellular processes, including energy production and transmission. It has been shown to be tumorigenic and is found at high levels in plasma membranes and muscle cells. ATP binds to the adenylate cyclase enzyme in the cell membrane and stimulates its activity, which increases intracellular levels of cyclic AMP (cAMP). Cyclic AMP activates protein kinase A, which phosphorylates proteins, leading to a cascade of reactions that result in cellular changes. ATP also has pharmacological effects on the plasma membrane by increasing its permeability to certain ions such as potassium ions. This leads to an increase in the rate of depolarization of the cell membrane, which causes an influx of calcium ions into the cell.</p>
    Formule :C10H15N5O13P3Na3
    Degré de pureté :Min. 95%
    Masse moléculaire :575.14 g/mol

    Ref: 3D-NA02978

    1g
    2.440,00€
  • 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine

    CAS :
    <p>3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine is a nucleoside that is used in the antiviral drug Aciclovir. It is an analog of 2'-deoxyadenosine and inhibits viral DNA synthesis by acting as a chain terminator. 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine has shown some anticancer activity against human tumor cells in culture, but its mechanism of action is not well understood.</p>
    Formule :C23H17Cl2FN2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :523.29 g/mol

    Ref: 3D-ND22464

    5mg
    303,00€
    10mg
    401,00€
    25mg
    650,00€
    50mg
    1.055,00€
    100mg
    1.916,00€