Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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1-(3'-azido-3'-deoxy-b-D-ribofuranosyl)-5-nitro-2(1H)-pyridinone
CAS :<p>1-(3'-azido-3'-deoxy-b-D-ribofuranosyl)-5-nitro-2(1H)-pyridinone is a nucleoside analog that has antiviral and anticancer activities. It has been shown to be an activator of cellular DNA polymerase γ, which is involved in the DNA chain elongation process during DNA replication. 1-(3'-azido-3'-deoxy-b-D-ribofuranosyl)-5-nitro-2(1H)-pyridinone also inhibits the activity of human T cell leukemia virus type 1 (HTLV1) reverse transcriptase by binding to its active site and preventing the synthesis of viral DNA. This compound has a high quality with a purity > 98% and is not radioactive or toxic.</p>Degré de pureté :Min. 95%2'/3'-(N-Methylanthraniloyl)-adenosine-5'-monophosphate triethylammonium salt
CAS :<p>2'/3'-(N-Methylanthraniloyl)-adenosine-5'-monophosphate triethylammonium salt is an antiviral agent that is based on ribonucleosides. This drug has been shown to be effective against cancer and herpes simplex virus type 1 (HSV-1) and may have potential as a treatment for HIV. It also inhibits the growth of tumors in animal models. 2'/3'-(N-Methylanthraniloyl)-adenosine-5'-monophosphate triethylammonium salt is synthesized by reacting ribonucleosides with N-(2,2,2,-trimethylpropyl)anthranilic acid chloride in the presence of triethylamine. The resulting product can be purified by column chromatography or recrystallization.</p>Formule :C18H21N6O8PDegré de pureté :Min. 95%Masse moléculaire :480.37 g/molN-(13C-Methyl)adenosine
<p>N-(13C-Methyl)adenosine is a modified nucleoside with antiviral activity. It is an analog of adenosine and has been shown to inhibit the replication of DNA viruses, such as herpes simplex virus type 1 and type 2, varicella zoster virus, and cytomegalovirus. This drug has also been found to be effective in animal models against human immunodeficiency virus (HIV) infection. N-(13C-Methyl)adenosine does not inhibit the replication of cellular RNA viruses such as influenza A virus or vesicular stomatitis virus.</p>Degré de pureté :Min. 95%Masse moléculaire :3,656.49 g/molTricyclic nucleoside phosphate
CAS :<p>Akt activation inhibitor</p>Formule :C13H17N6O7PDegré de pureté :Min. 95%Masse moléculaire :400.28 g/molN2-Isobutyryl-2'-deoxy-5'-O-pixylguanosine
<p>N2-Isobutyryl-2'-deoxy-5'-O-pixylguanosine is a modified nucleotide that has been shown to be an activator of the protein kinase C and may have anticancer and antiviral properties. N2-Isobutyryl-2'-deoxy-5'-O-pixylguanosine is a synthetic nucleoside that is structurally similar to ribonucleosides and deoxyribonucleosides, but contains a modified base. The nucleotide is activated by phosphorylation and then undergoes hydrolysis in the cell to form diphosphate. This product has CAS No. 125965-04-3, purity at 99%, and high quality.</p>Formule :C33H31N5O6Degré de pureté :Min. 95%Masse moléculaire :593.64 g/mol3’-Deoxy-3’C-methyl-5-methyluridine
CAS :<p>3’-Deoxy-3’C-methyl-5-methyluridine is a novel and efficient phosphoramidite monophosphate, which can be used in the synthesis of DNA. This product has antiviral activity against HIV and some other viruses. The phosphoramidite is modified with a diphosphate group, which increases the efficiency of DNA synthesis. 3’-Deoxy-3’C-methyl-5-methyluridine is synthesized by modifying 5′ position with a C6 methylaminomethyl group and coupling with the 3′ deoxynucleoside.</p>Degré de pureté :Min. 95%5-(Azidomethyl)-2’-deoxyuridine
CAS :<p>5-azidomethyl-2-deoxyuridine (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU (NE08701). Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.</p>Formule :C10H13N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :283.24 g/mol5-Methoxy-4’-thiouridine
<p>5-Methoxy-4’-thiouridine is a monophosphate nucleoside that is synthesized by the phosphorylation of 5-methoxy-4’-thioguanosine. It has antiviral activity, which is due to its ability to inhibit viral DNA polymerase and prevent the production of viral DNA. 5-Methoxy-4’-thiouridine also inhibits the synthesis of deoxyribonucleosides and ribonucleosides, thereby preventing the formation of RNA and DNA. This agent has been shown to be an anticancer agent that can cause cell death by inhibiting protein synthesis.</p>Degré de pureté :Min. 95%4’,5’-Didehydro-5’-deoxy-5-methyluridine
CAS :<p>4’,5’-Didehydro-5’-deoxy-5-methyluridine is a monophosphate nucleoside that is used as an antiviral agent. It has been shown to be active in the treatment of HIV and hepatitis B. 4’,5’-Didehydro-5’-deoxy-5-methyluridine also has anticancer properties and has been shown to inhibit cell proliferation in vitro by interfering with DNA synthesis. This product is an intermediate for the synthesis of other nucleosides and phosphoramidites.</p>Degré de pureté :Min. 95%6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydroxyamino-1H-pyrazolo[3,4-d]pyrimidine
<p>6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydroxyamino-1H-pyrazolo[3,4-d]pyrimidine is a modified nucleoside with antiviral and anticancer properties. It is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydroxyamino-1H pyrazolo[3,4 d]pyrimidine can be used in the synthesis of phosphoramidites for DNA synthesis and for the production of monophosphate nucleotides. The compound has been shown to inhibit the growth of cells in culture that are resistant to other antiinfectives such as erythromycin and chloramphenicol.</p>Degré de pureté :Min. 95%3’-Deoxy-3’-fluoro-N6-hydroxyadenosine
CAS :3’-Deoxy-3’-fluoro-N6-hydroxyadenosine (3'-DF) is an antiviral nucleoside that inhibits viral DNA synthesis and has shown cytotoxic effects in human cancer cells. 3'-DF is a novel chemical compound that was first synthesized in 1994. It is a nucleotide analog that is structurally related to adenosine, with the exception of the fluoro atom at position 6 on the ribose sugar. 3'-DF inhibits DNA polymerase and RNA polymerase by competitively binding to the ribonucleotide reductase enzyme, inhibiting the production of new RNA and DNA molecules. This compound also has been shown to inhibit protein synthesis in cancer cells without affecting normal cells.Degré de pureté :Min. 95%5'-O-Tosyl-2',3'-O-isopropylideneadenosine
CAS :<p>5'-O-Tosyl-2',3'-O-isopropylideneadenosine is a novel modified nucleoside with antiviral and anticancer activities. It is an activator of the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. This drug has been shown to have anticancer activity in a variety of tumor cell lines, including leukemias, lymphomas, and sarcomas. In addition, it has been shown to be active against HIV and herpes simplex virus type 1 (HSV-1). 5'-O-Tosyl-2',3'-O-isopropylideneadenosine is also known by CAS No. 5605-63-0.</p>Formule :C20H23N5O6SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :461.49 g/mol5'-O-MMT-thymidine 3'-CE phosphoramidite
CAS :<p>5'-O-MMT-thymidine 3'-CE phosphoramidite is a novel anticancer drug that is modified from the natural nucleoside thymidine. It has been shown to inhibit the activity of DNA polymerase, preventing DNA synthesis and replication. It also inhibits viral DNA replication, including HIV and herpes simplex virus type-1 (HSV-1). 5'-O-MMT-thymidine 3'-CE phosphoramidite has antiviral properties against HIV and HSV-1. This nucleoside is synthesized by reacting 5'-O-methyl cytidylic acid with an activated phosphite in the presence of triethylamine in dichloromethane. The product is purified by column chromatography on silica gel and recrystallization from acetonitrile.</p>Formule :C39H47N4O7PDegré de pureté :Min. 95%Masse moléculaire :714.81 g/mol7-Allyl-7,8-dihydro-8-oxoguanosine
CAS :<p>Agonist of toll-like receptors TLR7</p>Formule :C13H17N5O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :339.3 g/mol5'-O-Tritylthymidine
CAS :5'-O-Tritylthymidine is a nucleoside that is found in human mitochondrial DNA. It is synthesized from uridine by the enzyme thymidylate synthase and can be converted to thymine by the enzyme thymidine phosphorylase. 5'-O-Tritylthymidine has been shown to inhibit cancer cell growth, but its mechanism of action is not clear. It may inhibit xylene production. 5'-O-Tritylthymidine also causes an increase in p53 activity, which may lead to apoptosis of cancer cells.Formule :C29H28N2O5Degré de pureté :Min. 95%Masse moléculaire :484.54 g/mol7-Deazaadenosine- 2', 3'- dideoxy- 7[3- (trifluoroacetyl) amino] - 1- propyn- yl
CAS :<p>7-Deazaadenosine is a synthetic nucleoside that is used as an antiviral and antitumor agent. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. 7-Deazaadenosine also has antiviral activity, inhibiting viral DNA synthesis by interfering with the enzyme DNA polymerase. 7-Deazaadenosine has been shown to be more potent than other deoxyribonucleosides against various HIV strains, including HIV-1 group M and HIV-1 group O. This drug was originally developed for use as a chemotherapeutic agent but has since been used as a research reagent for studying the mechanism of action of various drugs on DNA.</p>Formule :C16H16F3N5O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :383.33 g/molN6-Benzoyl-2'-chloro-2'-deoxy-5'-O-DMT-adenosine
The N6-benzoyl-2'-chloro-2'-deoxy-5'-O-DMT-adenosine is a novel nucleoside that is a potent inhibitor of the human immunodeficiency virus type 1 (HIV-1) and has been shown to be effective against cancer. It is a phosphoramidite nucleoside with high purity and high quality, which can be used as an antiviral agent or an anticancer agent. The chemical name for this compound is 2'-(N6-Benzoyl)-2'-deoxyadenosine 5'-O-(DMT). This product is also known as NBDT, and it has been modified by changing the ribose sugar to DMT. NBDT inhibits viral replication by preventing the formation of DNA from RNA in the reverse transcription process. This process requires two enzymes: HIV reverse transcriptase and DNA polymerase α. The first enzyme, HIV reverse transcriptase,Degré de pureté :Min. 95%1-(Arabinofuranosyl)-5-azidomethyluracil
CAS :<p>1-(Arabinofuranosyl)-5-azidomethyluracil (AFAU) is a novel nucleoside that is synthesized by the reaction of 5-azido-1-(2'-deoxyribofuranosyl) uracil with phosphoramidite. The synthesis of this nucleoside has been used as a model for the synthesis of other deoxyribonucleosides. AFAU is an activator of ribonucleotide reductase and has shown activity against DNA and RNA viruses, such as influenza virus, herpes simplex virus type 1, and human immunodeficiency virus type 1.</p>Degré de pureté :Min. 95%9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl-b-L-ribofuranosyl)-6-chloropurine
CAS :<p>9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl-b-L-ribofuranosyl)-6-chloropurine is a modified nucleoside. It is synthesized by attaching an acetyl group to the 2' position of the sugar moiety and a toluoyl group to the 3' position of the ribose moiety. 9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl]-6 chloropurine has been shown to be an activator of RNA polymerase II and III, which are involved in transcription and replication. This drug also has antiviral properties against influenza virus, herpes simplex virus type 1, Epstein Barr Virus (EBV), and HIV as well as anticancer activity against human cells. 9-[2'-O-Acetyl]-6 chlor</p>Degré de pureté :Min. 95%5'-Amino-5'-deoxythymidine
CAS :<p>5'-Amino-5'-deoxythymidine is a nucleoside that is structurally related to thymidine. It has been shown to be a substrate for fatty acid synthase, which is a key enzyme in the synthesis of membrane lipids. 5'-Amino-5'-deoxythymidine has been shown to induce tumorigenesis in mouse bladder carcinoma cells. This compound also does not form stable complexes with DNA duplexes and can inhibit uptake of thymidylate into cells by competitive inhibition. 5'-Amino-5'-deoxythymidine binds to the cell surface and acts as an antibody response modifier.</p>Formule :C10H15N3O4Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :241.24 g/mol
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