Oligonucléotides
Les oligonucléotides sont de courtes séquences de nucléotides, généralement comprises entre 2 et 25 bases, qui sont synthétisées pour une variété d'applications de recherche et thérapeutiques. Ils jouent un rôle crucial en biologie moléculaire, servant d'amorces pour l'amplification de l'ADN, de sondes pour détecter des séquences spécifiques et d'agents pour le silençage et la régulation des gènes. Les oligonucléotides sont largement utilisés dans des techniques telles que la PCR, la qPCR, le séquençage et la thérapie antisens. Chez CymitQuimica, nous offrons une sélection complète d'oligonucléotides de haute qualité pour soutenir vos recherches en génétique, biotechnologie et diagnostics médicaux.
63 produits trouvés pour "Oligonucléotides".
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
5-Me Bz dC β-Cyanoethyl Phosphoramidite (5-Methyl-5'-O-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
CAS :Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormule :C47H54N5O8PCouleur et forme :White PowderMasse moléculaire :847.371T β-Cyanoethyl Phosphoramidite (5'-O-Dimethoxytritylthymidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
CAS :Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormule :C40H49N4O8PCouleur et forme :White PowderMasse moléculaire :744.3288iBu dG β-Cyanoethyl Phosphoramidite (5'-O-Dimethoxytrityl-N2-isobutyryl-2'-deoxyguanosine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
CAS :Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormule :C44H54N7O8PCouleur et forme :White Off-White PowderMasse moléculaire :839.37715Bz dA β-Cyanoethyl Phosphoramidite (5'-O-Dimethoxytrityl-N6-benzoyl-2'-deoxyadenosine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
CAS :Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormule :C47H52N7O7PCouleur et forme :White Off-White PowderMasse moléculaire :857.36658Bz dC β-Cyanoethyl Phosphoramidite (5'-O-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
CAS :Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormule :C46H52N5O8PCouleur et forme :White PowderMasse moléculaire :833.35535ODN 1668
CAS :ODN 1668 is an immunostimulatory class B CpG oligodeoxynucleotide (ODN)， used as an agonist for TLR9, and upregulates the level of IgM.Couleur et forme :Yellow ViscousMasse moléculaire :6364.1HSV-60mer sodium
HSV-60mer sodium is a 60 bp double-stranded oligonucleotide that includes viral DNA motifs from the herpes simplex virus 1 (HSV-1) genome. Transfection of HSV-60mer effectively induces IFN-β in a manner dependent on STING, TBK1, and IFN regulatory factor 3 (IRF3).Couleur et forme :Odour SoliddsVACV-70mer sodium
dsVACV-70mer sodium is a 70 base pair double-stranded oligonucleotide that contains a viral DNA motif derived from vaccinia virus DNA. It effectively induces IFN-β through a STING-dependent mechanism.Couleur et forme :Odour SolidSalanersen
CAS :Salanersen is an antisense oligonucleotide targeting SMN2 and is utilized in the study of spinal muscular atrophy (SMA).CpG ODN 10101
CAS :CpG ODN 10101 (CPG 10101) is an oligodeoxynucleotide agonist of TLR9 with antiviral activity for the treatment of chronic infections.Degré de pureté :99.16%Couleur et forme :White SolidRugonersen sodium
CAS :Rugonersen sodium is a locked nucleic acid (LNA)-modified antisense oligonucleotide (ASO) designed to reduce the silencing of ubiquitin protein ligase E3A (UBE3A). Angelman syndrome (AS) refers to a severe neurodevelopmental disorder caused by the loss of neuronal E3 ligase UBE3A, and Rugonersen has been studied for its potential use in the treatment of AS.Formule :C204H235N63Na19O109P19S19Couleur et forme :SolidMasse moléculaire :6948.005'6-FAM-UUCUCCGAACGUGUCACGUTT, ACGUGACACGUUCGGAGAATT
5'6-FAM-UUCUCCGAACGUGUCACGUTT, ACGUGACACGUUCGGAGAATT is a fluorescein (FAM)-labeled oligonucleotide, denoted by the sequence provided.Couleur et forme :Odour SolidISD Control sodium
ISD (interferon stimulatory DNA) Control sodium is a non-immunostimulatory single-stranded oligonucleotide with a sequence identical to its double-stranded counterpart, ISD.Couleur et forme :Odour SolidRosomidnar
CAS :PNT100: 24-base DNA oligo targeting BCL-2 regulatory region; halts tumor cell growth, induces death.Formule :C227H291O141P23Couleur et forme :SolidMasse moléculaire :7220.63FITC-labeled Agatolimod sodium
FITC-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake andCouleur et forme :Odour SolidBiotin-labeled ODN 1018 sodium
Biotin-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, serves as a tool for assessing cellular uptake and localization of CpG ODNs throughCouleur et forme :Odour SolidBiotin-labeled ODN 1826 sodium
Biotin-labeled ODN 1826 (sodium), a class B CpG oligodeoxynucleotide (ODN), serves as a TLR9 agonist and facilitates assessment of CpG ODN cellular uptake andCouleur et forme :Odour Solid3-Azidopropionic Acid Sulfo-NHS Ester
CAS :Water-soluble 3-Azidopropionic Acid Sulfo-NHS Ester reacts via Click Chemistry; labels proteins' amines.Formule :C7H7N4NaO7SCouleur et forme :SolidMasse moléculaire :314.21Nusinersen
CAS :Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.Degré de pureté :99.54%Couleur et forme :SolidODN 2395
CAS :ODN 2395, a class C oligodeoxynucleotide and TLR9 agonist, serves as a vaccine adjuvant. Its sequence is 5'-tcgtcgttttcggcgc:gcgccg-3' [1].Couleur et forme :SolidMasse moléculaire :7035ssVACV-70mer sodium
ssVACV-70mer sodium is a 70 bp single-stranded oligonucleotide containing a viral DNA motif derived from vaccinia virus DNA. Unlike its double-stranded counterpart, dsVACV 70mer, ssVACV-70mer sodium does not act as an IFN inducer.CpG ODN 10101 sodium
CpG ODN 10101 sodium is a synthetic oligodeoxynucleotide (ODN) that functions as a Toll-like receptor 9 (TLR9) agonist. When combined with HH2(VQLRIRVAVIRA-NH2), it serves as an effective inducer of cytokine/chemokine expression in vitro. CpG ODN 10101 sodium stimulates dendritic cells (DC) to secrete IFN and activates B cells. It possesses antiviral and immunomodulatory properties, influencing chronic HCV infection.Couleur et forme :Odour SolidODN 2216 sodium
ODN 2216 sodium is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. It induces significant production of IFN-α and IFN-β. The compound stimulates IFN-α through pDC (plasmacytoid dendritic cells) and produces IL-12(p40) via DC (dendritic cells). ODN 2216 triggers peripheral blood mononuclear cells (PBMC) to produce IFN-γ indirectly, mediated by IFN-α/β. Additionally, ODN 2216 sodium can activate NK cells and enhance IFN-γ production in TCR-triggered CD4+ T cells.Couleur et forme :Odour SolidODN TTAGGG sodium
ODN TTAGGG sodium, an inhibitory oligonucleotide (ODN), is an antagonist of TLR9, AIM2, and cGAS. It exerts immunosuppressive effects by inhibiting AIM2 inflammasome activation and cGAS activation through competitive interaction with DNA. This compound can be utilized in research on autoimmune diseases such as lupus. The sequence for ODN TTAGGG is 5'-T-T-A-G-G-G-T-T-A-G-G-G-T-T-A-G-G-G-T-T-A-G-G-G-3'.Couleur et forme :Odour SolidUDP-N-acetyl-D-Glucosamine sodium hydrate
UDP-N-acetyl-D-Glucosamine sodium hydrate participates in cell wall synthesis and signal transduction research.Formule :C17H27N3O17P2·xNa·xH2OCouleur et forme :White SolidMasse moléculaire :607.35 (free base)KDM5D Human Pre-designed siRNA Set A
KDM5D Human Pre-designed siRNA Set A contains three siRNA pairs designed for various regions of the KDM5D (Human) gene. The set also includes a negative control, a FAM-labeled negative control, and a positive control.Salanersen sodium
Salanersen sodium is an antisense oligonucleotide that targets SMN2, used in the research of spinal muscular atrophy (SMA).Marpinersen sodium
Marpinersen sodium is an antisense oligonucleotide that inhibits the production of ataxin-2, commonly utilized in research on amyotrophic lateral sclerosis (ALS).Biotin-labeled Agatolimod sodium
Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of cellular uptake and localization ofCouleur et forme :Odour SolidBiotin-labeled ODN 2395 sodium
Biotin-labeled ODN 2395 (sodium), a Class C oligodeoxynucleotide and TLR9 agonist, serves to assess cellular uptake and localization of CpG ODN through a biotinCouleur et forme :Odour SolidFITC-labeled ODN TTAGGG sodium
FITC-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide that functions as an antagonist of TLR9, AIM2, and cGAS.Couleur et forme :Odour SolidFITC-labeled ODN 1668 sodium
FITC-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN), functions as a TLR9 agonist.Couleur et forme :Odour SolidBiotin-labeled ODN 1668 sodium
Biotin-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN) and TLR9 agonist, facilitates the assessment of cellular uptake and localization ofCouleur et forme :Odour SolidANGPTL4 Human Pre-designed siRNA Set A
The ANGPTL4 Human Pre-designed siRNA Set A consists of three pairs of siRNA targeting various regions of the ANGPTL4 (Human) gene, as well as a negative control, a FAM-labeled negative control, and a positive control.Couleur et forme :Odour SolidATR Human Pre-designed siRNA Set A
ATRHuman Pre-designed siRNA Set A consists of three siRNA pairs designed to target different regions of the ATR (Human) gene. The set also includes a negative control, a FAM-labeled negative control, and a positive control.Couleur et forme :Odour SolidSND1 Human Pre-designed siRNA Set A
The SND1 Human Pre-designed siRNA Set A comprises three pairs of siRNA targeted to various regions of the SND1 (Human) gene, along with a negative control, a FAM-labeled negative control, and a positive control.Couleur et forme :Odour SolidFITC-labeled ODN 1826 sodium
FITC-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake andCouleur et forme :Odour SolidFITC-labeled ODN 2395 sodium
FITC-labeled ODN 2395 (sodium), a class C oligodeoxynucleotide and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and localization throughCouleur et forme :Odour SolidFITC-labeled ODN 1018 sodium
FITC-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, facilitates the assessment of CpG ODN cellular uptake and localization through confocalCouleur et forme :SolidMasse moléculaire :8171Biotin-labeled ODN TTAGGG sodium
Biotin-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide (ODN) that functions as an antagonist to TLR9, AIM2, and cGAS.Couleur et forme :Odour SolidATP1A1 Human Pre-designed siRNA Set A
The ATP1A1 Human Pre-designed siRNA Set A consists of three pairs of siRNA designed for various regions of the ATP1A1 (Human) gene. This set also includes a negative control, a FAM-labeled negative control, and a positive control.Ano10 Mouse Pre-designed siRNA Set A
Ano10 Mouse Pre-designed siRNA Set A consists of three pairs of siRNAs designed for different regions of the Ano10 (Mouse) gene. It also includes a negative control, a FAM-labeled negative control, and a positive control.Kdm5d Mouse Pre-designed siRNA Set A
Kdm5d Mouse Pre-designed siRNA Set A consists of siRNAs targeting the Kdm5d gene (Mouse), along with a negative control, a positive control, and a FAM-labeled negative control.PLAUR Human Pre-designed siRNA Set A
PLAUR Human Pre-designed siRNA Set A includes three pairs of siRNA designed to target different regions of the PLAUR (Human) gene, along with a negative control, a FAM-labeled negative control, and a positive control.ASXL1 Human Pre-designed siRNA Set A
ASXL1 Human Pre-designed siRNA Set A comprises three pairs of siRNA designed for different regions of the ASXL1 (Human) gene. The set also includes a negative control, a FAM-labeled negative control, and a positive control.Couleur et forme :Odour SolidATG5 Human Pre-designed siRNA Set A
The ATG5 Human Pre-designed siRNA Set A comprises three pairs of siRNA targeted at various regions of the ATG5 (Human) gene, along with a negative control, a FAM-labeled negative control, and a positive control.Couleur et forme :Odour SolidRANGAP1 Human Pre-designed siRNA Set A
RANGAP1 Human Pre-designed siRNA Set A consists of three pairs of siRNA targeting various regions of the RANGAP1 (Human) gene, along with a negative control, a FAM-labeled negative control, and a positive control.Couleur et forme :Odour SolidODN D-SL03
CAS :ODN D-SL03, a C class CpG oligonucleotide, stimulates PBMCs, activating B cells, NK cells & monocytes, and can inhibit tumor growth.Couleur et forme :SolidMasse moléculaire :9345Zeleciment basivarsen
CAS :Zeleciment basivarsen (DYNE-101) is an antibody oligonucleotide conjugate (AOC), consisting of a Fab antibody named Zeleciment that binds to the transferrin receptor 1 (TfR1) on muscle cells, and an antisense oligonucleotide known as Basivarsen. This compound targets the RNA of the mutant dystrophia myotonica-protein kinase (DMPK) for RNase H-mediated degradation, and is utilized in the study of myotonic dystrophy type 1 (DM1).Thiazole Orange
CAS :Thiazole Orange is a dye that can be used for reticulocyte analysis.Formule :C26H24N2O3S2Degré de pureté :99.29% - 99.93%Couleur et forme :SolidMasse moléculaire :476.61
