Anthracyclines
Les anthracyclines sont une classe d'antibiotiques antitumoraux puissants largement utilisés en chimiothérapie anticancéreuse. Ces composés agissent en s'intercalant dans l'ADN, perturbant ainsi la fonction de la topoisomérase II et empêchant la réplication des cellules cancéreuses. Les anthracyclines sont particulièrement efficaces contre un large éventail de cancers, notamment les leucémies, les lymphomes et le cancer du sein. Cependant, leur utilisation est souvent limitée par leur cardiotoxicité, ce qui rend la recherche de formulations plus sûres et plus efficaces une priorité. Chez CymitQuimica, nous proposons une sélection d'anthracyclines pour soutenir vos recherches en oncologie, développement de médicaments et thérapie contre le cancer.
173 produits trouvés pour "Anthracyclines"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
7,8,9,10-Dehydro Doxorubicinone (~70%)
CAS :Produit contrôléFormule :C21H14O8Degré de pureté :~70%Couleur et forme :NeatMasse moléculaire :394.33Doxorubicin Imp B HBr salt
CAS :<p>Doxorubicin Imp B HBr salt is a drug product that is custom synthesized for research and development. It's high purity, analytical, and natural are well suited for pharmacopoeia, drug development, and niche. Doxorubicin Imp B HBr salt has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The CAS No. 148218-14-8 is an impurity standard that can be used in HPLC analysis to determine the purity of Doxorubicin Imp B HBr salt.</p>Formule :C29H34BrNO11BrHDegré de pureté :Min. 95%Masse moléculaire :733.4 g/molDoxorubicin Impurity 15
CAS :<p>Doxorubicin impurity 15 is a natural product that is used as an analytical reference standard in pharmacopoeia. It has been synthesized for use in drug development and research and development, and is available as a high-purity HPLC standard. Doxorubicin impurity 15 has a CAS number of 131086-18-5.</p>Formule :C31H38BrNO11Degré de pureté :Min. 95%Masse moléculaire :680.54 g/molDes[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone
CAS :<p>Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone is a research and development impurity standard for synthesis. It is a synthetic, high purity compound with a CAS number of 89991-52-6. The chemical is not found in nature and does not have any natural metabolites. Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone has been shown to be metabolized by the liver into various metabolites that have been identified through analysis of urine samples. The metabolite of des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone may be used as an analytical standard for HPLC methods.</p>Formule :C18H19N3O5Degré de pureté :Min. 95%Masse moléculaire :357.36 g/molEpirubicin
CAS :<p>Epirubicin, a doxorubicin derivative, is an antineoplastic, inhibits topoisomerase, DNA/RNA synthesis, and Foxp3, reducing T cell activity.</p>Formule :C27H29NO11Couleur et forme :SolidMasse moléculaire :543.52Mitoxantrone (2-hydroxyethyl)piperazine impurity
CAS :<p>Mitoxantrone is an anticancer drug that is used to treat various types of cancer. Mitoxantrone is a prodrug, which means it needs to be metabolized by the body to become active. The main metabolic pathway for mitoxantrone involves hydrolysis of the 2-hydroxyethyl piperazine impurity and formation of N-desmethylmitoxantrone, which is a metabolite that has been found to be more potent than the parent compound in inhibiting DNA synthesis. This impurity standard is used as a reference substance for quality control purposes during drug development. Mitoxantrone can also be synthesized with high purity and custom synthesis services are available upon request.</p>Formule :C22H26N4O6Degré de pureté :Min. 95%Couleur et forme :Brown PowderMasse moléculaire :442.47 g/molDoxorubicin Dimer Impurity-1
<p>Doxorubicin Dimer Impurity-1 is a drug product that is used as an HPLC standard. It is a metabolite of doxorubicin and has been shown to inhibit DNA synthesis in vitro. This impurity has been detected in the drug product using HPLC, and the purity of this impurity is greater than 98%. Doxorubicin Dimer Impurity-1 is a synthetic compound that has not been found in natural sources. It has been shown to be metabolized by human enzymes, such as esterases, glucuronidases, glutathione reductase, cytochrome P450 enzymes, and glucuronic acid conjugates. Doxorubicin Dimer Impurity-1 may also have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.</p>Formule :C54H56N2O21Degré de pureté :Min. 95%Masse moléculaire :1,069.02 g/mol
![Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FID21105.webp&w=3840&q=75)
