Système complémentaire
Le système du complément est une partie cruciale de la réponse immunitaire, composée d'une série de petites protéines qui améliorent la capacité des anticorps et des cellules phagocytaires à éliminer les agents pathogènes d'un organisme. Ces protéines travaillent ensemble pour opsoniser les agents pathogènes, induire des réponses inflammatoires et lyser directement les membranes des pathogènes, jouant un rôle vital dans l'immunité innée et la fonction immunitaire globale. Chez CymitQuimica, nous proposons des protéines du système du complément de haute qualité pour soutenir vos études immunologiques et recherches cliniques.
178 produits trouvés pour "Système complémentaire".
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
SB290157 trifluoroacetate
CAS :SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).Formule :C24H29F3N4O6Degré de pureté :98.93% - 99.89%Couleur et forme :White SolidMasse moléculaire :526.51PMX 205 acetate(514814-49-4 free base)
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).Formule :C47H66N10O8Degré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :899.09Ref: TM-T12506L1
1mg105,00€5mg266,00€10mg350,00€1mL*10mM (DMSO)374,00€25mg745,00€50mg1.189,00€100mg1.735,00€Vesencumab
CAS :Vesencumab (MNRP-1685A) is an IG1 antibody targeting NRP-1 with anti-angiogenic and anti-tumor activity. Vesencumab can be used to study solid tumors.Degré de pureté :99.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 99.2% (SDS-PAGE); 96.6% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.22 kDaDexamethasone
CAS :Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Formule :C22H29FO5Degré de pureté :98% - 99.91%Couleur et forme :Crystals From Ether (Ntp 1992)Masse moléculaire :392.46Tesidolumab
CAS :Tesidolumab, a fully human IgG1/λ anti-C5 monoclonal antibody, inhibits crovalimab and C5, preventing membrane attack complex formation.Degré de pureté :99.72% (SEC-HPLC) - > 95%Couleur et forme :LiquidMasse moléculaire :144.16 kDaCyclosporin A
CAS :Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor.Formule :C62H111N11O12Degré de pureté :99.00% - 99.92%Couleur et forme :White SolidMasse moléculaire :1202.61Ravulizumab
CAS :Ravulizumab (ALXN1210) is a humanized antibody for blocking complement activation, treating PNH, aHUS, and myasthenia gravis.Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :145.80 kDaVilobelimab
CAS :Vilobelimab (CaCP-29, IFX-1), a monoclonal antibody, inhibits C5a to reduce inflammation and is researched in sepsis and COVID-19 studies.Degré de pureté :99% (SDS-PAGE); 98.9% (SEC-HPLC) - 99% (SDS-PAGE); 98.9% (SEC-HPLC)Couleur et forme :Transparent LiquidMasse moléculaire :145.86 kDaAvdoralimab
CAS :Avdoralimab (IPH 5401) is a humanized monoclonal antibody targeting complement C5a receptor 1 (C5aR1).Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :145.9 kDaLampalizumab
CAS :Lampalizumab (RG 7417) is a humanized monoclonal antibody targeting Factor D, which can be used in cardiovascular disease research.Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :143.8 kDaSutimlimab
CAS :Sutimlimab: monoclonal antibody, inhibits complement protein C1, treats cold agglutinin-induced hemolysis.Degré de pureté :> 95%Couleur et forme :Transparent LiquidMasse moléculaire :144.8 kDaPIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Formule :C71H123N19O21S2·xC2HF3O2Couleur et forme :SolidFactor B-IN-5
CAS :Factor B-IN-5 is a complement factor B inhibitor, which can be used to study immune-related diseases.Formule :C27H32N2O4Degré de pureté :98.19%Couleur et forme :SoildMasse moléculaire :448.55Vensobafusp alfa
CAS :Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.Couleur et forme :LiquidPIC1 PA
CAS :PIC1 PA, a peptide consisting of 15 amino acids, serves as an effective analog of PIC1 that inhibits complement activation mediated by the classical pathway. Functionally, PIC1 PA interferes with the interaction between the C1s-C1r-C1r-C1s/MASPs and the collagen-like region (CLR) of C1q/MBL. It specifically binds to the CLR of C1q, with an average equilibrium dissociation constant (KD) of 33.3 nM when binding purified C1q.Formule :C71H123N19O21S2Couleur et forme :SolidMasse moléculaire :1642.98BM213
CAS :BM213 is a useful organic compound for research related to life sciences and the catalog number is T35399.Formule :C43H70N12O10Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :915.09Zilucoplan TFA
Zilucoplan TFA (RA101495), a 15-amino acid macrocyclic peptide, serves as a potent inhibitor of complement component 5 (C5).Formule :(C2H4O)nC126H186N24O32·C2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3562.18 (free base)C1s-IN-1 trihydrochloride
CAS :C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.Formule :C16H22Cl3N5Couleur et forme :SolidMasse moléculaire :390.74Complement C1s-IN-1
CAS :Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexesFormule :C22H20F2N6ODegré de pureté :97.77%Couleur et forme :Yellow SolidMasse moléculaire :422.43C5a Anaphylatoxin (human)
CAS :C5a Anaphylatoxin (human) is a pro-inflammatory peptide that functions as a leukocyte chemoattractant, utilized in researching inflammation and immune responsesFormule :C350H578N108O107S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :8267.51Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Formule :C128H190N24O33Couleur et forme :SolidMasse moléculaire :2593.02POT-4 acetate
POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.Formule :C74H106N22O20S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1687.9Factor B-IN-1
CAS :Factor B-IN-1 is a Factor B inhibitor.Formule :C19H16N4O2Couleur et forme :SolidMasse moléculaire :332.3559Anti-GC1q R/C1QBP Antibody (60.11)
Anti-GC1q R/C1QBP Antibody (60.11) is a mouse IgG1, κ chimeric antibody designed to target human GC1q R/C1QBP. The recommended isotype control for this antibody is Mouse IgG1 kappa, Isotype Control.Couleur et forme :Odour LiquidPOT-4 TFA
POT-4 TFA, a Compstatin derivative, inhibits C3 activation, for macular degeneration research.Formule :C74H103F3N22O20S2Couleur et forme :SolidMasse moléculaire :1741.87ARC186
ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.Couleur et forme :SolidMasse moléculaire :120702.76TLQP-21
CAS :TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Formule :C107H170N40O26Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2432.75Pozelimab
CAS :Pozelimab (REGN 3918) is a humanized antibody targeting component 5 (C5), used for research on Pozelimab disease.Degré de pureté :98.94% (SEC-HPLC) - 98.94% (SEC-HPLC)Couleur et forme :Transparent LiquidMasse moléculaire :144.78 kDaPMX 205
CAS :PMX 205 is an effective complement antagonist of the C5a receptor.Formule :C45H62N10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :839.04L-156,602
CAS :L-156,602 has a wide range of applications in life science related research.Formule :C38H64N8O13Couleur et forme :SolidMasse moléculaire :840.973C5a Receptor agonist, mouse, human
CAS :C5a Receptor Agonist (mouse, human) is a bioactive peptide derived from the C-terminus of the complement fragment 5 anaphylatoxin (C5a), functioning as anFormule :C44H72N10O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :853.11Claseprubart
CAS :Claseprubart is a monoclonal antibody that targets human complement C1s. It specifically binds to complement C1s, inhibiting the activation of the complement system and exerting immunosuppressive effects. Claseprubart shows potential for research in autoimmune diseases and inflammation-related conditions.Couleur et forme :LiquidATWLPPR Peptide TFA
ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.Formule :C42H62F3N11O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :954Campneoside II
CAS :Campneoside II, a compound extracted from the wood of Paulownia tomentosa var. tomentosa, demonstrates remarkable anti-complement activity [1].Formule :C29H36O16Couleur et forme :SolidMasse moléculaire :640.59PMX 205 Trifluoroacetate
PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.Formule :C47H63F3N10O8Couleur et forme :SolidMasse moléculaire :953.06Olendalizumab
CAS :Olendalizumab is an anti-C5a mAb that inhibits neutrophil activation and cytokine storms by blocking the C5a/C5aR axis for sepsis and viral infection research.Couleur et forme :LiquidPMX-53
CAS :PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Formule :C47H65N11O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :896.09JPE-1375
CAS :JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.Formule :C49H63FN10O9Couleur et forme :SolidMasse moléculaire :955.08Vemircopan
CAS :Vemircopan is a complement factor D inhibitor.Formule :C29H28BrN7O3Couleur et forme :SolidMasse moléculaire :602.493Certepetide
CAS :Certepetide, or iRGD, is a cyclic peptide that enhances tumor penetration and researches solid cancers.Formule :C37H60N14O14S2Couleur et forme :SolidMasse moléculaire :989.09Compstatin TFA
Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).Formule :C68H100F3N23O19S2Couleur et forme :SolidMasse moléculaire :1664.79Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.Couleur et forme :Odour SolidAMY-101
CAS :AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.Formule :C83H117N23O18S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1789.11BCX 1470 hydrochloride
BCX 1470 hydrochloride is a serine protease inhibitor with anti-inflammatory activity that inhibits factor D hemolytic activity and may be used to study edema.Formule :C14H11ClN2O2S2Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :338.83Anti-CD88/C5AR1 Antibody (G2_anti-C5aR)
Anti-CD88/C5AR1 Antibody (G2_anti-C5aR) is a human monoclonal antibody (mAb) targeting C5AR1.Couleur et forme :Odour LiquidC3a (70-77) (TFA)
C3a (70-77) (TFA) (Complement 3a (70-77) TFA) is an octapeptide derived from the COOH-terminus of Complement 3a, exhibiting 1–2% C3a biological activity.Formule :C37H62F3N13O12Degré de pureté :99.92%Couleur et forme :White SolidMasse moléculaire :937.96ASP-1948
ASP-1948 is a human monoclonal antibody targeting NRP1/VEGF165R/CD34. It is capable of reversing the inhibitory effects of regulatory T cells and can be applied in the study of solid tumors.Couleur et forme :Odour LiquidtLyP-1 peptide
CAS :tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.Formule :C31H59N15O10SCouleur et forme :SolidMasse moléculaire :833.96CK3 peptide
CAS :CK3 peptide is an NRP-1-targeting peptide with the amino acid sequence CLKADKAKC. It specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging demonstrate that CK3 peptide significantly accumulates in xenograft tumors in nude mice. CK3 peptide is applicable for molecular imaging studies of breast cancer.Formule :C40H72N12O12S2Couleur et forme :SolidMasse moléculaire :977.203Greziprubart
Greziprubart is a humanized IgG1κ monoclonal antibody that targets C5a, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Couleur et forme :Odour Liquid
