Système complémentaire
Le système du complément est une partie cruciale de la réponse immunitaire, composée d'une série de petites protéines qui améliorent la capacité des anticorps et des cellules phagocytaires à éliminer les agents pathogènes d'un organisme. Ces protéines travaillent ensemble pour opsoniser les agents pathogènes, induire des réponses inflammatoires et lyser directement les membranes des pathogènes, jouant un rôle vital dans l'immunité innée et la fonction immunitaire globale. Chez CymitQuimica, nous proposons des protéines du système du complément de haute qualité pour soutenir vos études immunologiques et recherches cliniques.
177 produits trouvés pour "Système complémentaire".
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Danicopan
CAS :Danicopan (ACH-4471), an oral factor D inhibitor, binds strongly (Kd 0.54 nM) and may treat PNH and aHUS.Formule :C26H23BrFN7O3Degré de pureté :99.94%Couleur et forme :White SolidMasse moléculaire :580.41Ref: TM-T8509
1mg90,00€2mg129,00€5mg203,00€1mL*10mM (DMSO)260,00€10mg310,00€25mg527,00€50mg755,00€100mg1.044,00€Compstatin
CAS :Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.Formule :C66H99N23O17S2Degré de pureté :>99.99%Couleur et forme :White SolidMasse moléculaire :1550.77TLQP 21 acetate
TLQP 21 acetate: Agonist for C3aR1, EC50 - 10.3 μM (mouse), 68.8 μM (human); VGF-derived with endo/extraendocrine traits.Formule :C109H174N40O28Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :2492.8Avacopan
CAS :Avacopan (CCX168) is a C5aR antagonist with selective and oral activity. Avacopan can be used to treat ANCA-related vasculitis. Cost-effective and quality-assured.Formule :C33H35F4N3O2Degré de pureté :97% - 99.9%Couleur et forme :SolidMasse moléculaire :581.64C3a 70-77 2TFA(63555-63-5(free base))
C3a 70-77 2TFA(63555-63-5(free base)) (Complement 3a (70-77)) is an octapeptide corresponding to the COOH terminus of C3a.Formule :C39H63N13O14Degré de pureté :>99.99%Couleur et forme :White SolidMasse moléculaire :1052.00Leukadherin-1
CAS :Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Formule :C22H15NO4S2Degré de pureté :98.49% - 98.93%Couleur et forme :White SolidMasse moléculaire :421.49Eculizumab
CAS :Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5Degré de pureté :98.20%Couleur et forme :Transparent LiquidMasse moléculaire :145.74 kDaLEP(116-130)(mouse)TFA(258276-95-8 free base)
LEP(116-130)(mouse) is a synthetic leptin peptide fragment.Formule :C66H110F3N19O26SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :1674.77BCX 1470 methanesulfonate
CAS :BCX 1470 inhibits factor D & C1s better than trypsin (IC50: 96 nM & 1.6 nM, 3.4- & 200-fold).Formule :C15H14N2O5S3Couleur et forme :SolidMasse moléculaire :398.48PMX 53 acetate(219639-75-5 free base)
CAS :PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50Formule :C49H69N11O9Degré de pureté :99.91%Couleur et forme :White SolidMasse moléculaire :956.16Ref: TM-TP2334
1mg105,00€5mg233,00€10mg344,00€1mL*10mM (DMSO)359,00€25mg532,00€50mg735,00€100mg982,00€200mg1.333,00€Compstatin control peptide acetate
CAS :Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3.Formule :C68H105N23O19Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :1548.70ADH-503
CAS :ADH-503 (GB1275) is an orally available, allosteric CD11b small molecule agonist.Cost-effective and quality-assured.Formule :C27H28N2O5S2Degré de pureté :99.03% - >99.99%Couleur et forme :Yellow SolidMasse moléculaire :524.7Ref: TM-T7776
2mg34,00€5mg49,00€1mL*10mM (DMSO)52,00€10mg75,00€25mg120,00€50mg178,00€100mg259,00€200mg384,00€JR14a
CAS :JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) is a potent antagonist of human complement C3a receptor.Formule :C25H26Cl2N4O3SDegré de pureté :99.76% - 99.96%Couleur et forme :SolidMasse moléculaire :533.47Complement C5a Protein, Human, Recombinant
Complement C5 Protein, Human, Recombinant (Complement C5a) is expressed in E.Degré de pureté :SDS-PAGE: 94.9%; SEC-HPLC: 93.5%Couleur et forme :White Lyophilized PowderMasse moléculaire :8.3 kDa (predicted); 8.3 kDa (reducing conditions)AMY-101 acetate
AMY-101 acetate (Cp40 acetate) is a peptide, an inhibitor of C3 Complement in gingivitis and periodontitis, reduces inflammation and lowers MMP-8 and MMP-9.Formule :C85H121N23O20S2Degré de pureté :98.80% - 99.98%Couleur et forme :SolidMasse moléculaire :1849.14CR1 Protein, Human, Recombinant
Activity: Not Tested
Expression system: E. coli
Length: 41-234, PartialCouleur et forme :Lyophilized PowderMasse moléculaire :21.6 kDa (Predicted)Ref: TM-TMPH-03875
5µg123,00€10µg195,00€20µg325,00€50µg410,00€100µg489,00€200µg702,00€500µg1.134,00€1mg1.648,00€Complement factor D Protein, Rat, Recombinant (His)
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternateCouleur et forme :Lyophilized PowderMasse moléculaire :27.8 kDa (predicted)Ref: TM-TMPH-03272
5µg114,00€10µg178,00€20µg305,00€50µg447,00€100µg627,00€200µg964,00€500µg1.701,00€1mg2.673,00€Properdin Protein, Mouse, Recombinant (His)
A positive regulator of the alternate pathway of complement.Couleur et forme :Lyophilized PowderMasse moléculaire :51.9 kDa (predicted)Ref: TM-TMPH-02844
5µg98,00€10µg158,00€20µg255,00€50µg385,00€100µg532,00€200µg822,00€500µg1.459,00€1mg2.277,00€C1QA Protein, Mouse, Recombinant (E. coli, His)
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.Degré de pureté :98% - > 85% as determined by SDS-PAGECouleur et forme :White Lyophilized PowderMasse moléculaire :29.1 kDa (predicted)Complement C5 Protein, Rat, Recombinant (His & Myc)
Complement C5 Protein, Rat, Recombinant (His & Myc) is expressed in E.Couleur et forme :Lyophilized PowderMasse moléculaire :14.0 kDa (predicted)Ref: TM-TMPH-03270
5µg120,00€10µg195,00€20µg324,00€50µg489,00€100µg670,00€200µg964,00€500µg1.558,00€1mg2.277,00€Complement factor I Protein, Rat, Recombinant (His & Myc)
Complement factor I Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :69.2 kDa (predicted)Ref: TM-TMPH-03273
5µg164,00€10µg264,00€20µg442,00€50µg833,00€100µg1.350,00€200µg1.575,00€500µg1.935,00€C1SB Protein, Mouse, Recombinant (His & Myc)
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system.Couleur et forme :Lyophilized PowderMasse moléculaire :82.4 kDa (predicted)Ref: TM-TMPH-02603
5µg120,00€10µg195,00€20µg324,00€50µg489,00€100µg670,00€200µg964,00€500µg1.558,00€1mg2.277,00€Complement C3 Protein, Bovine, Recombinant (His & SUMO)
Complement C3 Protein, Bovine, Recombinant (His & SUMO) is expressed in E.Couleur et forme :Lyophilized PowderMasse moléculaire :39.5 kDa (predicted)Ref: TM-TMPH-00231
5µg120,00€10µg195,00€20µg324,00€50µg489,00€100µg670,00€200µg964,00€500µg1.558,00€1mg2.277,00€Complement C5a Protein, Pig, Recombinant (His)
Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process.Couleur et forme :Lyophilized PowderMasse moléculaire :10.6 kDa (predicted)Ref: TM-TMPH-03107
5µg133,00€10µg215,00€20µg358,00€50µg537,00€100µg760,00€200µg1.071,00€500µg1.755,00€Complement factor D Protein, Rat, Recombinant (His & Myc)
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternateCouleur et forme :Lyophilized PowderMasse moléculaire :29.8 kDa (predicted)Ref: TM-TMPH-03271
5µg52,00€10µg82,00€20µg118,00€50µg202,00€100µg315,00€200µg570,00€500µg1.251,00€1mg2.295,00€C1QA Protein, Human, Recombinant (His & Myc)
C1QA Protein, Human, Recombinant (His & Myc) is expressed in E. coli.Couleur et forme :Lyophilized PowderMasse moléculaire :30.7 kDa (predicted)Ref: TM-TMPH-01128
5µg78,00€10µg111,00€20µg178,00€50µg268,00€100µg384,00€200µg592,00€500µg1.054,00€1mg1.648,00€C5AR1 Protein-VLP, Human, Recombinant (His)
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.Couleur et forme :Lyophilized PowderMasse moléculaire :41.1 kDa (predicted)Ref: TM-TMPH-01022
5µg248,00€10µg414,00€20µg698,00€50µg1.144,00€100µg1.684,00€200µg2.835,00€500µg5.653,00€C1QA Protein, Mouse, Recombinant (His)
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.Degré de pureté :90% - 92%Couleur et forme :Lyophilized PowderMasse moléculaire :25.6 kDa (predicted)Complement C8g Protein, Human, Recombinant (His)
C8 is a constituent of the membrane attack complex.Degré de pureté :95%Couleur et forme :Lyophilized PowderMasse moléculaire :26.4 kDa (predicted)Ref: TM-TMPH-01134
5µg78,00€10µg111,00€20µg178,00€50µg268,00€100µg384,00€200µg592,00€500µg1.054,00€1mg1.648,00€Complement factor B Protein, Mouse, Recombinant (His)
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb.Couleur et forme :Lyophilized PowderMasse moléculaire :87.0 kDa (predicted)Ref: TM-TMPH-02607
5µg98,00€10µg158,00€20µg255,00€50µg385,00€100µg532,00€200µg822,00€500µg1.459,00€1mg2.277,00€C5AR1 Protein, Mouse, Recombinant (His & KSI)
Activity: Not Tested
Expression system: E. coli
Length: 306-351, PartialCouleur et forme :Lyophilized PowderMasse moléculaire :20.4 kDa (Predicted)Ref: TM-TMPH-04212
5µg93,00€10µg133,00€20µg213,00€50µg305,00€100µg401,00€200µg620,00€500µg1.108,00€1mg1.728,00€C5AR1 Protein, Mouse, Recombinant (MBP & His-Avi), Biotinylated
Activity: Not Tested
Expression system: E. coli
Length: 306-351, PartialCouleur et forme :Lyophilized PowderMasse moléculaire :52.8 kDa (Predicted)Ref: TM-TMPH-04213
5µg132,00€10µg212,00€20µg353,00€50µg444,00€100µg530,00€200µg762,00€500µg1.234,00€1mg1.783,00€C1QL1 Protein, Mouse, Recombinant (His)
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.Couleur et forme :Lyophilized PowderMasse moléculaire :26.9 kDa (predicted)C1QL3 Protein, Mouse, Recombinant (His & Myc)
May regulate the number of excitatory synapses that are formed on hippocampus neurons.Couleur et forme :Lyophilized PowderMasse moléculaire :28.6 kDa (predicted)C5AR1 Protein, Human, Recombinant (Cell-Free, His)
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.Degré de pureté :90%Couleur et forme :Lyophilized PowderMasse moléculaire :40.7 kDa (predicted)Complement C4-B Protein, Mouse, Recombinant (His)
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway.Couleur et forme :Lyophilized PowderMasse moléculaire :39.0 kDa (predicted)Ref: TM-TMPH-02605
5µg98,00€10µg158,00€20µg255,00€50µg385,00€100µg532,00€200µg822,00€500µg1.459,00€1mg2.277,00€C1RA Protein, Mouse, Recombinant (His & Myc)
C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.Couleur et forme :Lyophilized PowderMasse moléculaire :85.7 kDa (predicted)Ref: TM-TMPH-02602
5µg98,00€10µg158,00€20µg255,00€50µg385,00€100µg532,00€200µg822,00€500µg1.459,00€1mg2.277,00€Complement C3 Protein, Mouse, Recombinant (His & SUMO)
Complement C3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E.Couleur et forme :Lyophilized PowderMasse moléculaire :55.3 kDa (predicted)Ref: TM-TMPH-02604
5µg98,00€10µg158,00€20µg255,00€50µg385,00€100µg532,00€200µg822,00€500µg1.459,00€1mg2.277,00€Complement C8b Protein, Human, Recombinant (His)
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane ofCouleur et forme :Lyophilized PowderMasse moléculaire :67.0 kDa (predicted)Ref: TM-TMPH-01133
5µg120,00€10µg195,00€20µg324,00€50µg489,00€100µg670,00€200µg964,00€500µg1.558,00€1mg2.277,00€Complement C8a Protein, Human, Recombinant (His)
Complement C8a Protein, Human, Recombinant (His) is expressed in E. coli.Couleur et forme :Lyophilized PowderMasse moléculaire :65.8 kDa (predicted)Ref: TM-TMPH-01132
5µg93,00€10µg133,00€20µg213,00€50µg323,00€100µg442,00€200µg680,00€500µg1.198,00€1mg1.873,00€Properdin Protein, Mouse, Recombinant (His & Myc)
A positive regulator of the alternate pathway of complement.Couleur et forme :Lyophilized PowderMasse moléculaire :53 kDa (predicted)Ref: TM-TMPH-02845
5µg197,00€10µg329,00€20µg552,00€50µg1.044,00€100µg1.701,00€200µg2.673,00€500µg5.113,00€Complement C4-B Protein, Human, Recombinant (His & SUMO)
Complement C4-B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.Couleur et forme :Lyophilized PowderMasse moléculaire :49.1 kDa (predicted)Ref: TM-TMPH-01131
5µg78,00€10µg111,00€20µg178,00€50µg268,00€100µg384,00€200µg592,00€500µg1.054,00€1mg1.648,00€Complement C8 γ Protein, Human, Recombinant (His)
Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G.Couleur et forme :Lyophilized PowderMasse moléculaire :22 KDa (reducing condition)Ref: TM-TMPJ-00585
5µg84,00€10µg120,00€20µg178,00€50µg351,00€100µg563,00€200µg888,00€500µg1.710,00€1mg2.457,00€MBL2 Protein, Human, Recombinant (His)
Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins.Degré de pureté :> 99.9% - Greater than 95% as determined by reducing SDS-PAGE.Couleur et forme :Lyophilized PowderMasse moléculaire :31 KDa (reducing condition)Ref: TM-TMPJ-00136
5µg63,00€10µg90,00€20µg138,00€50µg245,00€100µg437,00€200µg782,00€500µg1.710,00€1mg2.457,00€Avacincaptad pegol sodium
CAS :Avacincaptad pegol (ARC1905) is an anti-C5 aptamer for AMD study, inhibiting C5 cleavage.Couleur et forme :SolidMasse moléculaire :53500Anti-Mouse CD11b Antibody (M1/70)
Anti-Mouse CD11b Antibody (M1/70) inhibits cell adhesion, kills cancer cells and alleviates fibrosis and inflammation.Degré de pureté :95% - 95%Couleur et forme :Transparent LiquidMasse moléculaire :150 kDaGefurulimab
CAS :Gefurulimab (ALXN-1720) is a bispecific antibody derived from humans, targeting complement C5 and albumin.Couleur et forme :LiquidCrovalimab
CAS :Crovalimab (SKY59; RO7112689) is an humanised monoclonal antibody that binds to complement C5 , paroxysmal nocturnal haemoglobinuria (PNH).Degré de pureté :95%Couleur et forme :Transparent LiquidMasse moléculaire :~150 kDaRovelizumab
CAS :Rovelizumab, Humanized anti-CD11/CD18 mAb, inhibits overactive leukocytes during shock, for MS, hemorrhagic shock, myocardial infarction, and stroke.Degré de pureté :95% - 95%Couleur et forme :Transparent LiquidRiliprubart
CAS :Riliprubart (SAR445088) is a humanised monoclonal antibody targeting C1s, applicable for neurological disorders such as CIDP, which inhibits activated C1s in the classical complement pathway.Degré de pureté :95% - 98.0% (SDS-PAGE); 99.0% (SEC-HPLC)Couleur et forme :Transparent LiquidMasse moléculaire :145.52 kDa
