Système complémentaire
Le système du complément est une partie cruciale de la réponse immunitaire, composée d'une série de petites protéines qui améliorent la capacité des anticorps et des cellules phagocytaires à éliminer les agents pathogènes d'un organisme. Ces protéines travaillent ensemble pour opsoniser les agents pathogènes, induire des réponses inflammatoires et lyser directement les membranes des pathogènes, jouant un rôle vital dans l'immunité innée et la fonction immunitaire globale. Chez CymitQuimica, nous proposons des protéines du système du complément de haute qualité pour soutenir vos études immunologiques et recherches cliniques.
191 produits trouvés pour "Système complémentaire".
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C5aR-IN-2
CAS :C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.Formule :C36H40FN5O2Couleur et forme :SolidMasse moléculaire :593.73BCX 1470
CAS :BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.Formule :C14H10N2O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.37Anti-Human Complement Factor B Antibody
Anti-Complement Factor B Antibody is a potent inhibitory antibody targeting complement factor B. Anti-Complement Factor B Antibody demonstrates the capacity to suppress complement-mediated inflammatory responses and provides essential utility for researching alternative pathway-driven immune disorders.Masse moléculaire :145.59 kDa (Predicted)Isocyclosporin A
CAS :Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.Formule :C62H111N11O12Couleur et forme :SolidMasse moléculaire :1202.6112NRP1 antagonist 2
CAS :NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.Formule :C20H17ClN6OS2Couleur et forme :SolidMasse moléculaire :456.97FD-IN-1
CAS :FD-IN-1 is an orally active Factor D (FD) inhibitor (IC50=12 nM), inhibits Factor XIa and Tryptase β2 with IC50 values of 7.7 and 6.5 μM, respectively.Formule :C23H23NO4Degré de pureté :98.85%Couleur et forme :White SolidMasse moléculaire :377.433Anti-Human CD88/C5AR1 Antibody (G2_anti-C5aR)
Anti-CD88/C5AR1 Antibody (G2_anti-C5aR) is a human monoclonal antibody (mAb) targeting C5AR1.Couleur et forme :Odour LiquidASP-1948
ASP-1948 is a human monoclonal antibody targeting NRP1/VEGF165R/CD34. It is capable of reversing the inhibitory effects of regulatory T cells and can be applied in the study of solid tumors.Couleur et forme :Odour LiquidC1s-IN-1 trihydrochloride
CAS :C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.Formule :C16H22Cl3N5Couleur et forme :SolidMasse moléculaire :390.738MEDI7814
MEDI7814 is a humanized monoclonal antibody inhibitor targeting C5a and C5adesArg. It has binding affinities of 14 pM for recombinant human C5a and 8 pM for serum-purified human C5a. MEDI7814 shows potential for treating acute inflammatory conditions, including sepsis and renal ischemia-reperfusion injury.C3a Receptor Agonist
CAS :C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.Formule :C27H35N3O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :433.5857Complement C5-IN-1
CAS :Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).Formule :C24H32N2O6Degré de pureté :98.27%Couleur et forme :White SolidMasse moléculaire :444.5207Ref: TM-T10863
1mg75,00€5mg145,00€1mL*10mM (DMSO)159,00€10mg195,00€25mg312,00€50mg439,00€100mg628,00€NDT 9513727
CAS :NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.Formule :C36H35N3O4Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :573.68EG00229
CAS :EG00229 blocks VEGF-A/NRP1 binding, IC50 of 3 μM; doesn't affect VEGFR-1/2. It's an NRP1 antagonist.Formule :C19H20F3N7O7S3Degré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :611.595Ref: TM-T11153
1mg45,00€5mg103,00€1mL*10mM (DMSO)133,00€10mg148,00€25mg238,00€50mg352,00€100mg524,00€200mg749,00€C5aR-IN-1
CAS :C5aR-IN-1, a potent C5aR inhibitor, may aid in researching autoimmune and inflammatory diseases.Formule :C36H39F4N3O2Couleur et forme :SolidMasse moléculaire :621.71Factor D inhibitor 6
CAS :Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.Formule :C23H22ClFN6O3Couleur et forme :SolidMasse moléculaire :484.911Factor B-IN-2
CAS :Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.Formule :C25H32N2O4Couleur et forme :SolidMasse moléculaire :424.53Vemircopan
CAS :Vemircopan is a complement factor D inhibitor.Formule :C29H28BrN7O3Couleur et forme :SolidMasse moléculaire :602.482EG01377
CAS :EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.Formule :C26H30N6O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :586.68W-54011
CAS :W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).Formule :C30H37ClN2O2Degré de pureté :96.8%Couleur et forme :White SolidMasse moléculaire :493.08Ref: TM-T17250
1mg79,00€5mg120,00€1mL*10mM (DMSO)132,00€10mg184,00€25mg304,00€50mg491,00€100mg708,00€200mg963,00€
