Autres

<p>Stability Light Sensitive<br>Applications Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α.<br>References Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001), Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003), Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004),<br></p>

<p>Applications Furfural is a compound mainly found in agricultural byproducts, and is produced from the hydrolysis and dehydration of xylan contained in lignocellulose using solid acid catalysts. Furfural is also a potential platform for biofuels and inhibits fermentation in yeast.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lange, J., et al.: ChemSusChem, 5, 150 (2012); Mamman, A., et al.: Biofuels, Bioprod. Biorefin., 2, 438 (2008); Navarro, A.: Curr. Microbiol., 29, 87 (1994)<br></p>

<p>Applications Azure B is a dye used for staining semi-thin sections of plant tissues. Azure B is used for staining semi-thin sections of plant tissue. This dye is also useful in the NCCLS method for blood smears and Lillie's modified Nocht's method for paraffin sections. Dyes and metabolites.<br>References 1. Penney, D.P., et al. 2002. Biotech. Histochem. 77: 237-275. PMID: 12564600<br></p>

<p>Stability Hygroscopic<br>Applications Cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. This is a controlled substance (depressant) in the US but not in Canada. Sedative, hypnotic.<br>References Noble, S., et al.: Drugs, 55, 277 (1998), Musch, B., et al.: Int. J. Clin. Psychopharmacol., 5, 147 (1990),<br></p>

<p>Applications Fulvestrant (F862500) impurity F.<br></p>

<p>Applications 2-CHLOROTOLUENE (cas# 95-49-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Lindane-d6 is very toxic. It was an effective insecticide on mosquitoes, house flies, and on German and American cockroaches.<br>References Tanaka, K., et al.: Pestic. Biochem. Physiol., 6, 386-391 (1976)<br></p>

<p>Applications Cyclopropanecarboxylic Acid is used as a reagent in the synthesis of substituted 4-(thiophen-2-ylmethyl)-2H-phthalazin-1-ones as potent PARP-1 inhibitors. Also used as a reagent in the synthesis of 2-alkyloxazoles as potent and selective PI4KIIIβ inhibitors demonstrating inhibition of HCV replication.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, L., et al.: Bioorg. Med. Chem. Lett., 24, 3739 (2014); Keaney, E.P., et al.: Bioorg. Med. Chem. Lett., 24, 3714 (2014)<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications It is one of the two carotenoids contained within the retina.<br>References Karrer, et al.: Helv. Chim. Acta, 13, 268 (1930), Hlubucek, et al.: J. Chem. Soc. Perkin Trans., 1, 848 (1974), Maoka, T., et al.: Comp. Biochem. Physiol., 83B, 121 (1986),<br></p>

<p>Applications 5-9-Leuprolide is a metabolite of Leuprolide (L330590), a gonadotropin-releasing hormone (GnRH) analogue acting as an agonist at pituitary GnRH receptors.<br>References Handelsman, David J., et al.: J. of Steroid Biochem. and Mol. Bio., 141, 113-120 (2014);Okada, Hiroaki, et al.: Pharma. Res., 8(6), 787-91 (1991)<br></p>

<p>Impurity Eletriptan Impurity 14<br>Applications Tri-o-tolyl-Phosphine Oxide (Eletriptan Impurity 14) is an impurity of Eletriptan, a selective serotonin 5-HT1B and 5-HT1D receptor agonist and used to treat migraines.<br>References Willems, E., et al.: Arch. Pharmacol., 358, 212 (1998); Napier, C., et al.: Eur. J. Pharmacol., 368, 259 (1999); Goadsby, P.J., et al.: Neurology, 54, 156 (2000)<br></p>

<p>Applications It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. An antitumor agent.<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>

<p>Applications A labelled metabolite of Toluene.<br>References Gargas, M., et al.: Toxicol. Appl. Pharmacol., 98, 87 (1989), Commandeur, J., et al.: Pharmacol. Rev., 47(2), 271 (1995), Campo, P., et al.: Neurotoxicol. Teratol., 21, 427 (1999), Lohse, C., et al.: J. Agr. Food Chem., 48, 5913 (2000),<br></p>

<p>Applications Simethicone is an oral anti-foaming agent used to reduce bloating, discomfort and pain caused by excess gas in the stomach or intestinal tract. Simethicone is a mixture of polydimethylsiloxane and hydrated silica gel.<br>References Grinshpan, D., et al.: Pharmaceut. Chem. J., 42, 400 (2008), Agarwal, D., et al.: J. Pharmac., 20, 206 (1988),<br></p>