Glucides et Glycoconjugués

<p>Difucosyl-para-lacto-N-neohexaose is an extracellular, acidic oligosaccharide with a lactose backbone and two fucoses attached to the 2' position. Difucosyl-para-lacto-N-neohexaose is found in human milk and has been shown to be a potent inhibitor of the lectin anagyroides. Difucosyl-para-lacto-N-neohexaose is composed of tetraoses linked by α(1→4) glycosidic bonds. The linkage between the first two sugars of each tetraose can be either α(1→6) or β(1→3). The linkage between the second two sugars in each tetraose can be either β(1→4) or α(1→6). This linkage pattern restricts the possible structures to six different types,</p>

<p>Gala1-2Gal-HSA is a modified, complex carbohydrate. The carbohydrate is synthesized by methylating, glycosylating and polysaccharide synthesis to produce Gala1-2Gal-HSA. It has CAS No. and can be custom synthesized with high purity. Gala1-2Gal-HSA is a monosaccharide that can be fluorinated or saccharide that can be glycosylated or methylated. Gala1-2Gal-HSA has many applications in the biomedical field such as inhibiting inflammation and preventing cancer metastasis.</p>

<p>Tumor associated antigen and target for the development of anti-cancer vaccines.</p>

<p>Lacto-N-fucopentaose II-APD-HSA is a complex carbohydrate that has been chemically modified to include a fucose sugar. Lacto-N-fucopentaose II-APD-HSA is synthesized by the click reaction and then modified with the addition of an acetyl group. The product is then methylated and purified by HPLC. Lacto-N-fucopentaose II-APD-HSA can be used in a wide range of applications, including as a component in glycosylation reactions or as an adjuvant for fluorescence labelling.</p>

<p>Methyl 2-acetamido-2-deoxy-6-O-(b-D-galactopyranosyl)-a-D-glucopyranoside is a custom synthesis, modification and fluorination of a monosaccharide. The saccharide is modified with methylation and click modification at the 6th carbon position. This product is designed for use in the synthesis of complex carbohydrates.</p>

<p>Primeverose is a p-hydroxybenzoic acid that is found in the genus Primula and mammalian tissue. Primeverose has been shown to inhibit the activity of an enzyme called fatty acid activated, which is involved in the biosynthesis of anthraquinone glycosides. Primeverose is also able to hydrolyze enzymes such as primeverose and may act as a signal peptide for biological samples. The hydroxyl group on primeverose can form hydrogen bonds with other molecules and is present in food composition.</p>

<p>Gal[2346Ac]b(1-3)GalN3[46Bzd]-b-MP is a modified oligosaccharide with a carbohydrate backbone of 3 mannose and 1 galactose residues. The saccharide is synthesized from the monosaccharides methylated, glycosylated, and then fluorinated. Gal[2346Ac]b(1-3)GalN3[46Bzd]-b-MP has a CAS number of 71769-77-5.</p>

<p>3',4'-O-Carbonyl-6,6'-di-O-tert-butyldiphenylsilyl lactal is a synthetic oligosaccharide that has been modified with a click modification. It is comprised of 3 different monosaccharides, one saccharide, and one carbonyl group. This carbohydrate is synthesized from the natural sugar D-ribose, which is modified with an O-tert-butyldiphenylsilyl lactal. The synthesis begins with the addition of a methyl group to the sugar's primary hydroxyl group. Then the sugar is reacted with fluorine gas to form an ether bond between the sugar's primary hydroxyl and its secondary hydroxyl. The final step in the synthesis involves glycosylation of the terminal hydroxyl groups on each monosaccharide.</p>

<p>A modified heparin disaccharide</p>

<p>Tri-fucosyl-Lewis Y-heptasaccharide-APE, HSA is a complex carbohydrate that has been custom synthesized and glycosylated. It was modified with methylation and fluorination to create a high purity product. This complex carbohydrate has a CAS number of 107386-00-6 and is composed of sugar molecules. It is a polysaccharide with the following structure:</p>

<p>Neu5Troc[1Me,4789Ac]a(2-3)Gal[26Bn]-b-MP is a fatty acid that is localized in the microstructural component of the brain. The wild-type mice were given a diet containing Neu5Troc[1Me,4789Ac]a(2-3)Gal[26Bn]-b-MP and their brains were examined for changes in serotonin levels. Structural analysis showed that this fatty acid was not incorporated into serotonin receptors in the brain. Carbides were found to be responsible for the observed effects on serotonin levels.</p>

<p>1,4-B-D-Cellopentaitol is a high purity and custom synthesis sugar. It can be modified with fluorination, glycosylation, methylation, or modification. It has CAS No. 61473-65-2 and is an oligosaccharide with a saccharide backbone consisting of 1,4-linked D-glucopyranosyl units joined by alpha-(1,4) linkages and containing one or more monosaccharides (e.g., glucose) or disaccharides (e.g., cellobiose). The carbohydrate may be in the form of a complex carbohydrate.</p>

<p>6,1',6'-Tri-O-tertbutyldiphenylsilyl-sucrose is a high purity, custom synthesis chemical. It is an oligosaccharide and complex carbohydrate that is a Click modification of sucrose. This chemical has been fluorinated, glycosylated, and methylated.</p>

<p>DNS-SGN is a synthetic, high purity, methylated, glycosylated, complex carbohydrate. This product is custom synthesized and has been fluorinated with a click modification. DNS-SGN is CAS Number: 598-02-3.</p>

<p>T-antigen-HSA is a synthetic, high-purity, custom synthesis glycoprotein with click modification. It is a complex carbohydrate that contains an oligosaccharide and a saccharide, which are attached to the protein backbone through an amide linkage. T-antigen-HSA is synthesized using recombinant DNA technology and can be modified by fluorination, methylation, or other modifications. This product has CAS No.</p>

<p>Hyaluronic acid is a polysaccharide containing repeating disaccharide units of β-1,3-N-acetyl glucosamine and β-1, 4-glucuronic acid. A series of unsaturated oligosaccharides (oligouronic acids) are released from hyaluronic acid by the action of hyaluronidase on the umbilical cord (Weissman, 1954). This decasaccharide and other enzymatically produced polymer homologs have been of value in the study of hyaluronic acid metabolism in both healthy and diseased tissues (Hascall, 2019).</p>

<p>Man6GlcNAc (I) is a synthetic, fluorinated, monosaccharide that can be modified to produce a wide range of products. This product has been shown to have high purity and can be customized for specific applications. It is used in the production of complex carbohydrates with click modification and methylation. Man6GlcNAc (I) is often used as an intermediate in the synthesis of oligosaccharides such as glycosylated proteins or glycans.</p>

<p>Hyaluronate biotin (HB) is a modified form of hyaluronic acid. It is produced by the methylation and glycosylation of hyaluronic acid and it has an average molecular weight of 1000 kDa. HB is used in tissue engineering, cell culture, and as a contrast agent for magnetic resonance imaging. The modification of hyaluronate with biotin allows for the visualization of HB using immunofluorescence microscopy. Hyaluronate biotin is a synthetic product that can be custom-synthesized to customer specifications, such as purity level, oligosaccharide content, and monosaccharide content.</p>

<p>Maltotriose hydrate is a synthetic glycosylation product that is synthesized by the fluorination of maltotriose. Maltotriose hydrate is a sugar with a 3-D structure that is similar to maltodextrin, but with one less glucose residue. Maltotriose hydrate can be used in the synthesis of oligosaccharides and polysaccharides and has been shown to have high purity. Maltotriose hydrate can be modified by a variety of reactions, such as methylation, monosaccharide modification, or click chemistry. It has an CAS number and can be custom synthesized for clients' needs.</p>

<p>b-D-Lactosyltrichloroacetimidate heptaacetate is a glycosylation product of the b-D-lactose and trichloroacetic anhydride. This compound is used in the synthesis of oligosaccharides and polysaccharides. It has been shown to be a fluorinated, methylated, or click modified monosaccharide or disaccharide which can be prepared through custom synthesis, or by modification of existing saccharides. This compound has been found to have high purity with a CAS number of 1142022-76-1.</p>

<p>GM1-biotin ganglioside (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acid linked α2,3 to the inner galactose residue, ceramide linked β to position 1 on the reducing terminal glucose residue, and biotin to position 5 on sialic acid (Ledeen, 2009). GM1 ganglioside is abundant in all mammalian brains where it covers 10%-20% of the total ganglioside mixture. It is found in epithelial membranes and is a key element for bacterial toxicity and viral infection as it is the intestinal receptor for the cholera toxin, the B-subunits of heat-labile toxin, rotavirus, and simian virus 40. GM1 ganglioside functions as a neurotrophic and neuroprotective compound, and has been used therapeutically for diabetic and peripheral neuropathies. GM1 ganglioside also has the ability to bind amyloid-β proteins and is involved in Alzheimer’s pathogenesis (Chiricozzi, 2020).</p>

<p>(S)-3-((R)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a drug product of the drug development industry. It is a metabolite of 3-(1,2,4-triazol-1-ylmethyl)thiazolidine-4-carboxylic acid and has been used as an analytical standard for HPLC methods. The compound has been shown to be naturally occurring in humans. (S)-3-(1,2,4-Triazol-1ylmethyl)thiazolidine 4 carboxylic acid is also used as the impurity standard for the API 3-(1,2,4 triazol 1ylmethyl)thiazolidine 4 carboxylic acid.</p>

<p>Glycyl-lactose is a high purity, custom synthesis sugar that has been modified by fluorination, glycosylation, and methylation. This product is an oligosaccharide with a complex carbohydrate structure. Glycyl-lactose is synthesized from the monosaccharide glucose and the disaccharide lactose. This product can be used for Click chemistry reactions to modify proteins or other molecules on its surface. The CAS number for this product is 565-00-2.</p>

<p>Methylation is the addition of a methyl group to a molecule. The mannobiose-BSA is a methylated derivative of mannobiose, which has been modified by adding BSA. The modification of mannobiose-BSA with BSA facilitates its use in glycosylation reactions and as an intermediate in the synthesis of other complex carbohydrates. Methylation is also used to modify saccharides, polysaccharides, and oligosaccharides. Methyl groups are typically added using an organic chemical called dimethylamine or using an enzymatic reaction with SAM-dependent methyltransferases.</p>

<p>The H-BSA-15-atom spacer is a synthetic polymer that can be modified to create a glycolipid or glycopeptide. The H-BSA-15-atom spacer is an oligosaccharide with a molecular weight of 3,500 daltons and has been custom synthesized for this use. This product is highly purified and does not contain any other substances, such as proteins. It has been fluorinated to increase its resistance to degradation by enzymes. Glycosylation and click modification have also been performed on the H-BSA-15 atom spacer.</p>

<p>Heparin disaccharide I-P trisodium salt is a synthetic, highly pure, custom-synthesized heparin derivative with a unique sequence of saccharides. It has been fluorinated and methylated to increase its stability and resistance to degradation by enzymes. Heparin disaccharide I-P trisodium salt is glycosylated, which increases its solubility in water and reduces the risk of precipitation. This product is also modified using click chemistry to introduce an oligosaccharide at one end of the molecule.</p>

<p>Lacto-N-tetraose-BSA is a carbohydrate that contains four monosaccharides. It has been shown to be an autoantibody in patients with myasthenia gravis and can cause muscle weakness by binding to the muscle protein, actin. Lacto-N-tetraose-BSA has also been found to bind with nerve tissue and may be involved in the development of sclerosis. This carbohydrate is also negatively charged and agglutinates red blood cells. When used for immunofluorescence, it shows a strong reaction against glycoconjugates on the surface of neurons and nerve tissue. Lacto-N-tetraose-BSA binds specifically to bovine serum albumin (BSA) containing antibodies, which are produced by immune cells called B cells. The binding sites are located on the outer part of the molecule, near the sugar residues.</p>

<p>Methyl 3-O-(b-D-galactopyranosyl)-b-D-galactopyranoside is a disaccharide that is the residue of 6-fluoro-3-indoxyl beta-D-galactopyranoside. This product is a glycoside of methyl 3,6,3',6'-tetraacetate and b-D-galactose.</p>

<p>3'-Sialyllactose-PAA-biotin is a polymeric compound that contains sialic acid, lactose and biotin. It is a custom synthesis compound with a CAS number. 3'-Sialyllactose-PAA-biotin is an oligosaccharide made up of three monosaccharides, which are sialic acid, lactose and biotin. The polysaccharide has been modified by fluorination and click chemistry to be soluble in water. The carbohydrate has been synthesized from high purity raw materials and is free of contaminants. This compound can be used as a fluorescent probe for methylation reactions because it has been modified with Click chemistry.</p>

<p>3-O-b-D-Galactosylsucrose is a synthetic, fluorinated, high purity, oligosaccharide. It is a complex carbohydrate that contains an O-linked glycosylated monosaccharide. This product has been modified with a click modification. The CAS number for this product is 686717-73-7 and it can be synthesized to order.</p>

<p>Heparin disaccharide I-S, tetrasodium salt is a sodium salt of heparin that has been modified to contain two sulfate groups. The chemical modification of heparin disaccharide I-S, tetrasodium salt alters the molecule's charge and surface properties. This modification increases the molecule's ability to bind with cell surface markers and inhibits the activity of proteases. Heparin disaccharide I-S, tetrasodium salt is able to inhibit leukaemia proliferation in thp-1 cells by binding with cytoskeletal proteins such as vimentin and actin. This chemical also prevents PMA induced morphological changes in thp-1 cells. Heparin disaccharide I-S, tetrasodium salt is used as an anticoagulant in therapeutic settings. It is used to prevent blood clotting by inhibiting the activation of factors Xa and IIa. Heparin disaccharide</p>

<p>This is a custom synthesis of a polysaccharide.</p>

<p>The core trisaccharide of the ganglioside GD2,protected with a propargyl glycoside group, is the most prominent alkynyl glycoside used in oligosaccharide synthesis (Das, 2016). The structure (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>GM2-Oligosaccharide-spacer-NH2 ammonium is a complex carbohydrate with an oligosaccharide spacer and a hydrophobic NH2 group. The product is custom synthesized to your specifications and is available in high purity. It can be modified with fluorination or click chemistry. GM2-Oligosaccharide-spacer-NH2 ammonium is used in the synthesis of polysaccharides, saccharides, and carbohydrates. Some of its applications include modifying proteins, monosaccharides, and sugars.</p>

<p>Cellulose derivative, food thickener and emulsifier, bulk forming laxative</p>

<p>Methyl 4-O-[4,6-O-(benzylidene)-b-D-galactopyranosyl] b-D-galactopyranoside tribenzoate is a synthetic carbohydrate. It is an oligosaccharide that contains a complex carbohydrate. It is a high purity product and has been custom synthesized. The CAS number for Methyl 4-O-[4,6-O-(benzylidene)-b-D-galactopyranosyl] b-D-galactopyranoside tribenzoate is 59414-33-2. This product has been fluorinated and methylated. It also contains glycosylation and click modification.</p>

<p>Methyl 3-O-(a-D-galactopyranosyl)-b-D-galactopyranoside is a fluorinated methylated carbohydrate. It is an oligosaccharide with a sugar backbone. The sugar in the molecule is a monosaccharide, which is attached to other sugars through glycosylation. Methyl 3-O-(a-D-galactopyranosyl)-b-D-galactopyranoside has been synthesized and can be custom synthesized for specific requirements. It has high purity and can be obtained with a variety of modifications, such as fluorination to increase its stability. This compound can be used in a variety of applications, including the treatment of tuberculosis infections and cancer.</p>

<p>Lewis A trisaccharide methyl glycoside tetrabenzylether is a synthetic glycosylated oligosaccharide. It is a custom synthesis product that can be modified to the customer's specifications. The modification reaction yields a high-purity, complex carbohydrate with a saccharide content of 95%. This product is soluble in DMSO and DMF and is stable at pH 3-11.</p>

<p>Blood group B trisacchharide-APE-HSA is a synthetic carbohydrate that inhibits the synthesis of complex carbohydrates. The methylation of saccharides and polysaccharides can be accomplished by the addition of an amine to the 3′ hydroxyl group. In this reaction, the sugar is attached to a protein carrier (e.g., human serum albumin) via an amide bond, which prevents its degradation by proteases in the body. The modification of saccharides and polysaccharides is also accomplished through click chemistry, which is based on copper catalysis. This process involves attaching two functional groups through a copper-mediated reaction, forming a new carbon-carbon bond. Modification of saccharides and oligosaccharides can be accomplished using either chemical or enzymatic methods. Sugar modification can be achieved using high purity enzymes that have been custom synthesized for specific purposes (e.g., glycosylation). Carbohydrate modification can</p>

<p>Man-7 N-Glycan is a sugar that is composed of an oligosaccharide and a monosaccharide. The oligosaccharide is composed of an alpha-1,6-linked mannose, an alpha-1,2-linked mannose, and a beta-1,2-linked mannose. The monosaccharide is composed of glucose. This sugar has been modified with methylation and fluorination on the mannose side chains. It also contains glycosylation in the form of O-(alpha-D-mannopyranosyl)-(alpha-D-mannopyranosyl)n or O-(alpha-D-mannopyranosyl)-(beta-D-mannopyranosyl)m. A CAS number for this carbohydrate has not yet been assigned because it is custom synthesized. Man 7 N Glycan can be found in nature as a component of glycogen</p>

<p>α 1,4-glucoheptasaccharide derived from starch by hydrolysis and chromatography</p>

<p>NGA4 N-glycan is a monosaccharide that is methylated and glycosylated to form an oligosaccharide. It has a molecular weight of 1205 g/mol. This product can be used in the production of glycoconjugates, which are used in the treatment of cancer and inflammatory diseases.</p>

<p>Binder in tablets; food additive; has several pharmaceutical applications</p>

<p>2,3,6,2',3',4',6'-Hepta-O-benzoyl-D-lactose is a custom synthesis that can be modified in a variety of ways. It has a high degree of fluorination and methylation to provide protection against degradation by enzymes. The monosaccharide units are synthesized and then assembled into oligosaccharides with glycosylations. Modifications can include glycosylation at any position on the molecule as well as the addition of complex carbohydrates.<br>2,3,6,2',3',4',6'-Hepta-O-benzoyl-D-lactose is an example of a polysaccharide consisting of glucose units with other hexoses such as galactose or mannose.</p>

<p>Man-9-Glc N-Glycan is a synthetic carbohydrate that is a modification of the natural sugar, Man-9-GlcNAc. It can be used as an ingredient in pharmaceutical products, such as vaccines and other therapeutic agents. This product is a custom synthesis that can be produced to order.</p>

<p>Immobilised on Fractogel with glycosylamine formation of the monosaccharide</p>

<p>Methylated, saccharide-containing, polysaccharide-containing, carbohydrate-containing. CAS No.: 169800-74-1. Click modification: Click chemistry reaction with a reactive group on the saccharide or polysaccharide to form a bond with another molecule. Modification: The addition of one or more side chains to a saccharide or polysaccharide to produce a modified carbohydrate. Oligosaccharides: Carbohydrates that are composed of only two to ten monosaccharides. Glycosylation: The process in which a glycosyl group is transferred from an activated donor sugar to an acceptor molecule, forming glycosidic linkage (e.g., between sugars). High purity: The degree of chemical purity as expressed by the percent of impurities that may be present in the product (e.g., 99% pure). Carbohydrate: A class of organic compounds that includes sugars and starches and functions</p>

<p>Methyl 2-acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-4,6-O-benzylidene-2deoxyb-Dglucopyranoside is a sugar that is used in the preparation of various drugs. It has a pyranose ring and a pyranose form. The IR spectrum displays three distinct peaks at 1730 cm−1, 1590 cm−1 and 1410 cm−1. The axial orientation of the carbon atoms can be determined by looking at the absorption spectra. There are six carbons in the molecule with two axial orientations. The methyl group has an axial orientation and the acetamido group has an equatorial orientation. This compound is not soluble in water but dissolves well in methanol or ethanol. Methyl 2-acetamido 3 O</p>

<p>Lipid A monophosphoryl (MPL) is an adjuvant that stimulates the immune response to vaccines so that optimal protection can be achieved. MPL immunostimulant, a monophosphoryllipid A preparation derived from the lipopolysaccharide (LPS) of Salmonella minnesota R595. MPL is being considered as an adjuvant for a number of human vaccines, and experience to date has shown that it is safe, well tolerated, and able to provide a heightened immune response to coadministered antigens.</p>

<p>Gala1-3(Fuca1-2)Galb1-3GalNAc</p>

<p>Tetrasaccharide dp4 is a custom synthesis that is modified with fluorination, methylation, and click modification of the monosaccharides. It can be used for the synthesis of oligosaccharides and saccharides. Tetrasaccharide dp4 is a glycosylated carbohydrate that belongs to the group of polysaccharides. This product has CAS number 87392-00-6.</p>

<p>Man-3b N-Glycan is a glycan with a mannose backbone and an N-acetylglucosamine branch. This glycan can be customized to the user’s specification, including the desired sugar sequence and the length of the oligosaccharide. Man-3b N-Glycans are synthesized by modification of commercially available saccharides or by custom synthesis.</p>

<p>Octyl 2-acetamido-2-deoxy-b-D-glucopyranosyl-(1-2)-a-D-mannopyranosyl-(1-2)-b-D-glucopyranoside is a custom synthetic sugar that is used in the synthesis of complex carbohydrates. This product has been fluorinated to give it a high level of purity and is available for purchase at CAS No. 1268248-67-4. Octyl 2 acetamido 2 deoxy b D glucopyranosyl (1 2) a D mannopyranosyl (1 2) b D glucopyranoside has been modified with methylation, Click modification, and glycosylation. It can be used in polysaccharide synthesis or glycosylation reactions to produce polysaccharides with different properties.</p>

<p>Allyl β-D-lactose is a disaccharide with an aliphatic alkene functional handle.  This can be used as a functionalised monomer in the synthesis of glycopolymers.</p>

<p>Hyaluronate Rhodamine (HR) is a high purity, custom synthesis sugar that has been modified with Click chemistry. HR is a complex carbohydrate that consists of saccharides and oligosaccharides. HR has been synthesized using glycosylation and methylation reactions. Hyaluronate Rhodamine's CAS number is 1059-14-5.</p>

<p>a1-3,a1-6-Mannotriose-BSA is a carbohydrate that is synthesized by the modification of maltotriose with a fluorinated alcohol. It is an oligosaccharide made up of three glucose units linked together in a 1,3 configuration and one glucose unit linked together in a 1,6 configuration. The molecular weight of this carbohydrate is 793 Daltons. This product has been shown to be high purity and custom synthesis for use in research.</p>

<p>Methyl-O-b-D-glucopyranosyl-(1-3)-S-b-D-glucopyranosyl-(1-4)-O-4-thio-b-D-glucopyranosyl-(1,4)-b-D-[2] glucopyranoside is a synthetic saccharide with a single modification of 4'-fluoro substitution on the O6 position. This modification provides an increased stability to acid hydrolysis. Methylation and saccharide synthesis is performed in our lab and custom modifications are available upon request.</p>

<p>NGA2 Glycan, 2-AB labelled is a complex carbohydrate that is custom synthesized for research purposes. It is a high purity, high quality product that has been fluorinated and glycosylated. NGA2 Glycan, 2-AB labelled is used in the synthesis of oligosaccharides and polysaccharides. This product can be used for glycosylation, methylation and click modification.</p>

<p>6'-Sulpho Lewisa-BSA is a carbohydrate that has been modified with sulphur and fluorine. It is used as a fluorescence probe for the detection of carbohydrates in solutions, such as glycoproteins, glycopeptides, and glycolipids. 6'-Sulpho Lewisa-BSA is a complex carbohydrate that can be synthesized from the reaction of d-glucose and D-alanine. It can also be custom synthesized to suit the needs of the customer. This product is high purity and can be methylated or glycosylated. 6'-Sulpho Lewisa-BSA also has been modified by click chemistry to incorporate fluorescent groups at specific sites on the sugar chain.</p>

<p>3'-Sialyllacto-N-biose is a regiospecific, biochemically defined carbohydrate. It is a component of the glycan chains that are present on the surface of cell membranes. Lacto-n-biose has been shown to have inhibitory activity against the growth of Mycobacterium tuberculosis and Mycobacterium avium complex bacteria.</p>

<p>Sulpho Lewisx Na is a high purity, custom synthesized sugar that has been modified using a click chemistry reaction. It has been fluorinated and glycosylated to produce a complex carbohydrate. Sulpho Lewisx Na is a synthetic oligosaccharide produced with the intention of mimicking the structure of Lewisx in order to study its properties. The CAS number for this compound is 2641-19-2 and it can be found under the name Oligosaccharide, Monosaccharide, saccharide, Carbohydrate on Pubchem CID 1039264.</p>

<p>The Lipid A moiety of lipopolysaccharide forms the outer monolayer of the outer membrane in most Gram-negative bacteria. Escherichia coli lipid A is synthesized on the cytoplasmic side of the inner membrane by a conserved pathway of nine constitutive enzymes. Following attachment of the core oligosaccharide, nascent core-lipid A is flipped to the outer surface of the inner membrane by the ABC transporter MsbA, where the O-antigen polymer is attached. These complex glycoforms protect bacteria from antibiotics and complement-mediated lysis. The core and O-antigen domains are required for virulence and consequently are present in most clinical and environmental isolates (Raetz, 2007).</p>

<p>N,S-Carboxymethyl cysteine hydrochloride (NCC) is a drug product that is synthesized from cysteine. It has been used in analytical chemistry, metabolism studies, and drug development. NCC has been shown to be a natural metabolite of cysteine when administered orally to rats or mice. It is also an impurity standard for HPLC analysis and has been used as an API impurity in the synthesis of other drugs.<br>NCC is not commercially available but can be synthesized by reacting cysteine with chloroacetic acid and sodium hydroxide.</p>

<p>NGA4F N-Glycan is a modification of the N-glycan structure. It is an oligosaccharide composed of a single monosaccharide, methylated and glycosylated to form a polysaccharide with sugar groups on every other carbon. This product can be custom synthesized by our chemists at your request.</p>

<p>Hyaluronic acid is a polysaccharide containing repeating disaccharide units of β-1,3-N-acetyl glucosamine and β-1, 4-glucuronic acid. A series of unsaturated oligosaccharides (oligouronic acids) are released from hyaluronic acid by the action of hyaluronidase on umbilical cord (Weissman, 1954). This hexasaccharide and other enzymatically produced polymer homologs have been of value in the study of hyaluronic acid metabolism in healthy and diseased tissues (Hascall, 2019).</p>

<p>6'-Sialyllactosyl azide is a modified carbohydrate that can be synthesized from sialic acid and azide. The synthesis of 6'-sialyllactosyl azide is a modification of the glycosylation reaction. It is a monosaccharide, methylated at the hydroxyl group, and has one glycosylation site with a glycose molecule attached to it. This product has high purity and CAS number. It is also synthesized using synthetic methods and has a molecular weight of 232.6 g/mol.</p>

<p>2'-Fucosyllactose-BSA is a high purity, custom synthesis, synthetic oligosaccharide. It is a glycosylated and methylated monosaccharide that can be used for Click modification with azido-functionalized molecules. 2'-Fucosyllactose-BSA has a CAS number of 113959-06-8 and an Oligosaccharide content of &gt;95%. It is soluble in water and has a Glycosylation content of &gt;95% and a Carbohydrate content of &gt;95%.</p>

<p>Lewis Y tetrasaccharide-APE-HSA is a synthetic, high purity glycosylated oligosaccharide. It is composed of a Lewis Y tetrasaccharide linked to an APE peptide and HSA. The Lewis Y tetrasaccharide has been custom synthesized with click modification and fluorination. The APE peptide has been modified with glycosylation and methylation. The HSA has been modified with glycosylation, methylation, and acetylation. The oligosaccharide was synthesized using the solid phase method on a CEM Liberty Star Column. This glycoconjugate is CAS No., which can be found at Pubchem CID: 10609300.</p>

<p>Methyl a-D-Lamarabioside heptaacetate is a synthetic, fluorinated monosaccharide derived from the natural compound D-Lamarabioside. It is used as a building block for the synthesis of novel oligosaccharides and glycosylated proteins. This product also has applications in medical research and development, such as for the design of new drugs and vaccines, as well as in biotechnology and chemical engineering. Methyl a-D-laminarabioside heptaacetate is soluble in water with a melting point of 230°C. It can be used to modify proteins with high purity by introducing glycosylation sites. This product is also useful for click chemistry reactions.</p>

<p>1',6,6'-Trichloro sucrose is a complex carbohydrate that is synthesized from sucrose by the methylation of the hydroxyl groups followed by 1,6-dichlorination. This product has been shown to have a high degree of purity and can be used in a number of applications, including as a sugar substitute.</p>

<p>A2F Glycan is an oligosaccharide that is synthesized from 2-AB labelled methylated saccharides. It can be used in the synthesis of polysaccharides and as a click modification. A2F Glycan has a CAS number, which allows for custom synthesis, and it is available in high purity. The glycosylation of this product can be modified to suit the needs of the customer. The fluorination of A2F Glycan helps with the synthesis process and provides a complex carbohydrate with few impurities.</p>

<p>A mixture of sodium trigalacturonate &amp; tetragalacturonate (α-1,4 sodium galacturonotriose + α-1,4 sodium galacturonotetraose) is derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis (Combo, 2012). It is used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s), and gluconase(s) (Jayani, 2005). The addition of very short fragments of homogalacturonan, tri-galacturonate, and tetra-galacturonate oligosaccharides, restore development in dark-grown, de-etiolated seedling mutants, suggesting that they are unable to generate de-methylesterified pectin fragments. A model of spatiotemporally separated photoreceptive and signal-responsive cell types has been proposed, that contains overlapping subsets of the regulatory network of light-dependent seedling development (Sinclair, 2017).</p>

<p>Lacto-N-fucopentaose II-APD-KLH is a fluorinated, monosaccharide, synthetic, oligosaccharide, complex carbohydrate. It has CAS No. 21973-23-9 and a custom synthesis. Lacto-N-fucopentaose II-APD-KLH can be used as a glycosylation or polysaccharide with click modification or methylation. The high purity of this product is 99%.</p>

<p>4-O-(b-D-Galactopyranosyl)-D-glucosamine is a sugar that is found in the human body. It has been shown to have anti-cancer properties and is being studied as a potential therapeutic agent for squamous cell carcinoma. Basic structural analysis of 4-O-(b-D-Galactopyranosyl)-D-glucosamine has been performed on methyl glycosides, oligosaccharides, and bovine serum albumin. The sugar can be used to inhibit transcriptional regulation through its interactions with DNA. 4-O-(b-D-Galactopyranosyl)-D-glucosamine has also been found to inhibit the activities of enzymes involved in methyl glycoside synthesis, which may be related to its effects on cancer cells.</p>

<p>2,3,4,3',4'-Penta-O-isovaleryl-sucrose is a custom synthesis that has been modified by fluorination and methylation. It is a monosaccharide with a molecular weight of 596.84 g/mol. This compound is synthesized from sucrose through a click modification reaction and then further modified by glycosylation reactions to form an oligosaccharide or polysaccharide. 2,3,4,3',4'-Penta-O-isovaleryl-sucrose can be used in the production of complex carbohydrates such as Sucralose and Stevia.</p>

<p>Sucrose 1,6,6'-tricarboxylic acid trimethyl ester is a carbohydrate that has been fluorinated and methylated. It is a synthetic sugar that can be custom synthesized by our chemists to meet your specifications. This product is very pure and has a high degree of purity. It can be used as an oligosaccharide or as a monosaccharide in glycosylation or methylation reactions. Sucrose 1,6,6'-tricarboxylic acid trimethyl ester is also known as sucrose 3-fluoro-3-methylbutyrate, CAS No. 289711-92-8, or C12H18O7F3.</p>

<p>2, 3, 6, 2', 3', 4', 6'-Hepta-O-acetyl-D-maltose is a fluorinated monosaccharide that is used in the synthesis of glycosides. It has a CAS number of 56285-96-2 and can be custom synthesized. This product is an oligosaccharide that can be modified by glycosylation, methylation, or click modification. It is a complex carbohydrate with a high purity and can be used in the modification of sugars.</p>

<p>Man-2a N-glycan is a modification of the oligosaccharide mannose that is an important component of many glycoproteins. This product can be custom synthesized, and has been shown to have high purity. It is a carbohydrate that contains a monosaccharide and a polysaccharide. The glycan may also contain methylation, glycosylation, or fluorination. It has CAS No. 491845-49-9, which is the number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society to identify substances.</p>

<p>2,3,6,2',3',4',6'-Hepta-O-acetyl-b-D-lactosyl isothiocyanate is a fluorinated oligosaccharide that has been custom synthesized with a click modification. This compound is a high purity product and can be used in the synthesis of complex carbohydrates.</p>

<p>This product is a fatty acid that binds to the carbohydrate binding sites in the cell membrane of Caco-2 cells. It has been shown to inhibit the growth of cancer cells and radiation induced changes by binding to the sugar moieties on glycoproteins. This product also inhibits the production of glycoconjugates, which are important for cell-cell interactions and biological function. The disaccharide form has been found to be a diagnostic agent for cancer cells, with a structural formula that can be seen in the figure below.</p>

<p>Disialylated pentaose type I (DSI-1) is a disaccharide sugar that is synthesized in high purity by custom synthesis. It is a complex carbohydrate that consists of five monosaccharides: glucose, galactose, mannose, fucose and N-acetylneuraminic acid. DSI-1 has been shown to have glycosylation and methylation activity. This product has been modified with fluorination and saccharide modification, as well as Click chemistry. Disialylated pentaose type I is used in the pharmaceutical industry as an intermediate for the production of glycoconjugates and in the food industry to produce artificial sweeteners.</p>

<p>Lactose-sp-biotin is a complex carbohydrate that has been modified with biotin. It is synthesized by the click modification of lactose and spacer arm, followed by glycosylation with biotin. Lactose-sp-biotin is soluble in water, which makes it suitable for use as a food additive. This product can also be used for labeling and identification of biomolecules in various fields such as fluorescence, immunoassay, or immunohistochemistry.</p>

<p>Consumed in large amounts around the world as a food ingredient. Other applications of sucrose include its use in surfactants (esters), polyurethanes (polyols), plastics (alkyds) to produce dextrans (Leuconostoc mesenteroides fermentation) and ethanol (Saccharomyces cerevisiae fermentation).</p>

<p>O-[2-Acetamido-4,6-O-benzylidene-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-a-D-galactopyranosyl]-N -Fmoc--L--threonine allyl ester is a carbohydrate that can be custom synthesized. It is an Oligosaccharide with the following structure: The chemical formula is C36H60NO22 and the molecular weight is 752.8 g/mol. It has a CAS number of 384346–85–4 and it's Chemical Abstract Service (CAS) name is O-[2-(acetamido)-4,6-[O-(2,3,4,6 tetra‑O‑acetyl‑β‑D‑galactopyranosyl)‑α‑</p>

<p>NGA4B N-Glycan is a custom synthetic compound that can be modified to include methylation, fluorination, and other modifications. It is an oligosaccharide that is a polysaccharide composed of saccharides. The saccharides are monosaccharides or simple sugars. NGA4B N-Glycan is available at high purity for use in research and as a reagent.</p>

<p>Varenicline N-oxide is a synthetic drug product. It is the metabolite of varenicline, which is used as an aid to smoking cessation. Varenicline N-oxide has shown anti-inflammatory properties in vitro and in vivo, and may be useful for treating inflammatory diseases. Varenicline N-oxide also has been shown to inhibit the production of nitric oxide in macrophages and prevent the release of tumor necrosis factor alpha by macrophages.</p>

<p>4-Glucopyranosylmannose is a disaccharide compound, which is a synthetic carbohydrate derived from the enzymatic or chemical glycosylation processes. It consists of glucose and mannose units linked through a glycosidic bond. The compound is sourced through advanced synthetic methodologies involving specific glycosyltransferases or chemical catalysts that facilitate the precise attachment of these sugar moieties.</p>

<p>4-Methoxyphenyl 2,3,6-tri-O-acetyl-4-O-[2,4,6-tri-O-acetyl-3-O-(3,4,6-tri-O-acetyl-2-deoxy-2 -phthalimido)-bDglucopyranosyl]-bDgalactopyranoside is a high purity methylated glycoside of 4 methoxyphenol. The product has been modified by fluorination and Click chemistry to produce a complex carbohydrate. This modification can be used for the synthesis of oligosaccharides and polysaccharides.</p>

<p>Difucosyl-para-lacto-N-hexaose III is a custom synthesis. It is an oligosaccharide that belongs to the class of polysaccharides. It has a molecular weight of 1,000 Da and contains two monosaccharides: difucose and para-lactohexose. This product can be modified with fluorination or click chemistry. Difucosyl-para-lacto-N-hexaose III has a purity of &gt; 98% and CAS No., which is 93794-37-5.</p>

<p>2,3,4,6-Tetra-O-acetyl-1-O-(2,3,4-tri-O-benzoyl-a-L-fucopyranosyl)-D-galactopyranoside is a glycosylated polysaccharide that has been modified by methylation and fluorination. It is synthesized from the monosaccharide D galactopyranose with a 2,3,4,6 tetra O acetyl group at the 1 position.</p>

<p>NA2B N-Glycan is a custom synthesis of a polysaccharide, glycosylation sugar that contains an oligosaccharide chain. The NA2B N-Glycan is modified with fluorination, methylation, and click modification. It has no CAS number, but it is available for purchase from various suppliers. The NA2B N-Glycan is synthesized by the glycosylation of a saccharide and can be used as a complex carbohydrate.</p>

<p>1,2,3-Tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-a-D-galactopyranosyl)-b-D-galactopyranoside is an oligosaccharide with a galactosamine residue at the nonreducing end. It is a triacylglycerol that has been methylated and fluorinated. This product can be used as a sugar for synthesis of complex carbohydrates or for modification of monosaccharides. The high purity of this product makes it suitable for use in pharmaceuticals and other applications requiring high purity.</p>

<p>Methyl b-N-acetyllactosamine is a sulfated glycosaminoglycan (GAG) that is expressed in the brain and is involved in the development of myelin. This compound has been shown to inhibit the transfer of sulfate groups, which are essential for the synthesis of GAGs. Methyl b-N-acetyllactosamine inhibits transglycosylation reactions, which is a process by which sugar moieties are transferred from one molecule to another. This inhibition results in decreased cross-coupling reactions and decreases the production of GAGs. Methyl b-N-acetyllactosamine has been shown to have potent inhibitory properties against sulfonylating enzymes, such as regiospecifically catalyzed sulfonylation and transglycosylation. It also has been shown to inhibit the transition state in an enzymatic reaction involving triazoles.</p>

<p>Methyl a-N-acetyllactosamine is a custom synthesis of Methyl a-N-acetylgalactosamine. This compound has been modified by fluorination, methylation, and click modification to yield the desired product. The monosaccharide structure was synthesized from the corresponding glycosyl halide and protected amino acid. The glycosylation reaction between this monosaccharide and the oligosaccharide containing an unprotected hydroxyl group yields the desired product. The purity of this compound is greater than 99%.</p>

<p>Methyl 2-acetamido-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-a-D-glucopyranoside is a custom synthetic product. It is a complex carbohydrate made of an oligosaccharide and polysaccharide. This product is modified with saccharide and methylation. Methyl 2-acetamido-2-deoxy 3 O-(2,3,4,6 tetra -O acetyl b -D galactopyranosyl) a D glucopyranoside has CAS number 62998 28 1 and its purity level is high. The fluorination of this compound provides it with an additional feature of being water soluble. The synthesis of this product involves the use of the sugar in order to produce glycosylations.</p>

<p>NGA3F N-Glycan is a custom synthesis product that has been fluorinated, methylated, and modified with a click modification. It is a monosaccharide that can be found in the form of polysaccharides or glycosylations. This product is made of saccharides, which are carbohydrates that have been modified with glycosylation or polysaccharide modifications. NGA3F N-Glycan can be used in a variety of applications such as pharmaceuticals, food additives, and cosmetics.</p>

<p>Blood group B-HSA conjugate useful for raising antibodies</p>

<p>3-O-(2-Acetamido-2-deoxy-a-D-glucopyranosyl)-D-galactose is a synthetic compound that is synthesized by the reaction of 3,4,6-trihydroxypyranose with trifluoroacetic anhydride. The product can be purified to the desired level of purity using preparative HPLC or recrystallization. The CAS number for this compound is 97096-73-6.END&gt;</p>

<p>Heparin is a polysaccharide consisting of repeating units of glucosamine and glucuronic acid that has been shown to have anti-coagulant, antithrombotic, and anti-inflammatory properties. Heparin disaccharide III-H disodium salt is a heparin disaccharide that has been modified by the addition of sodium ions. This heparin disaccharide has been shown to inhibit the proliferation of leukaemia cells in vitro, which may be due to its inhibition of DNA synthesis or cell cycle progression. The mechanism by which this heparin disaccharide inhibits cell growth is not yet known. Research into this mechanism could lead to new treatments for cancer and other diseases.</p>

<p>Rhodionin is a natural product that has been shown to be effective as a food preservative. It is produced through the extraction of usnic acid from Rhodiola rosea and has been used in the study of amyloid protein. Rhodionin is an extractant that has been shown to be able to control analysis of sodium citrate in food composition. The use of rhodionin for this purpose was found to be practical and effective, with no significant changes in the quality or quantity of citric acid. This extractant also shows promise as an analytical method for the detection of ganoderma lucidum, human liver cancer cells, and flavonol glycosides.</p>