Cétones et Dérivés
Les cétones sont des composés organiques contenant un groupe carbonyle (C=O) lié à deux atomes de carbone, formant une structure où le groupe carbonyle est entouré par des groupes alkyle ou aryle. En pharmacologie, les cétones sont utilisées dans la formulation des API en raison de leur capacité à améliorer la solubilité et la stabilité des principes actifs. Certaines cétones possèdent des propriétés anti-inflammatoires, analgésiques et antimicrobiennes. Les dérivés des cétones incluent des composés dans lesquels le groupe carbonyle est modifié, comme les énols, qui ont des applications dans la synthèse de médicaments et comme intermédiaires chimiques dans la fabrication d’autres composés bioactifs. Les dérivés des cétones sont utilisés dans la conception de nouveaux médicaments, notamment pour traiter les maladies neurodégénératives, les troubles métaboliques et certains types de cancer, grâce à leurs effets spécifiques sur les enzymes et les processus cellulaires.
2393 produits trouvés pour "Cétones et Dérivés"
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Dihydro Capsaicin
CAS :Produit contrôlé<p>Applications Capsaicin (C175680) analog. A VR1 vaniloid receptor agonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ralevic, V., et al.: Biochem. Pharmacol., 65, 143 (2003), Thompson, R., et al.: Anal. Bioanal. Chem., 381, 1432 (2005), Tuoya., et al.: Life Sci., 78, 1515 (2006),<br></p>Formule :C18H29NO3Couleur et forme :White To Off-WhiteMasse moléculaire :307.434-Acetaminophen-d3 Sulfate Potassium Salt
CAS :Produit contrôlé<p>Applications 4-Acetaminophen-d3 Sulfate Potassium Salt is a deuterium labeled metabolite of Acetaminophen (A161220) (1,2,3).<br>References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961)(2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)<br></p>Formule :C8H5D3KNO5SCouleur et forme :NeatMasse moléculaire :272.33p-Ethylhydratropic Acid
CAS :<p>Impurity Ibuprofen EP Impurity N<br>Applications p-Ethylhydratropic Acid (Ibuprofen EP Impurity N) is a phenylacetic acid with potential antiinflammatory activities. p-Ethylhydratropic Acid is an impurity of Ibuprofen (I140000).<br></p>Formule :C11H14O2Couleur et forme :WhiteMasse moléculaire :178.231-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethan-1-one
CAS :Degré de pureté :97.0%Masse moléculaire :426.4880065917969Medetomidine-13C,d3 Hydrochloride
CAS :Produit contrôlé<p>Applications Labelled α2-adrenergic agonist. Sedative; analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987), Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987), Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988), Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996),<br></p>Formule :CC122H3H13N2·ClHCouleur et forme :White To Light YellowMasse moléculaire :240.753,5-Dimethyl-2-methoxyacetophenone
CAS :Formule :C11H14O2Degré de pureté :98%Masse moléculaire :178.231rac α-Hydroxy Ibuprofen
CAS :Produit contrôlé<p>Impurity Ibuprofen EP Impurity M<br>Applications A potential precursor of Ibuprofen and Naproxen. Antiinflammatory agent.<br>References Williams, K., et al.: Pharm. Ther., 46, 273 (1990), Evans, A., et al.: Eur. J. Clin. Pharmacol., 42, 237 (1992), Tucker, G., et al.: Lancet, 355, 1085 (2000), Tan, S., et al.: Xenobiotica, 32, 683 (2002), Fura, A., et al.: J. Pharm. Biomed. Anal., 32, 513 (2003),<br></p>Formule :C13H18O3Couleur et forme :White To Off-WhiteMasse moléculaire :222.284-Acetylbibenzyl
CAS :Formule :C16H16ODegré de pureté :95+%Couleur et forme :SolidMasse moléculaire :224.303rac Ketorolac
CAS :Produit contrôlé<p>Applications Ketorolac is an analgesic; anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Etman, M., et al.: Pharm. Technol., 32, 58 (2008), Chelladurai, S., et al.: Chem. Pharm. Bull., 56, 1596 (2008), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formule :C15H13NO3Couleur et forme :Off White SolidMasse moléculaire :255.274′-Methoxyacetophenone
CAS :Formule :C9H10O2Degré de pureté :99.0%Couleur et forme :Solid, White crystallineMasse moléculaire :150.177N-Acetyl-4-benzoquinone Imine
CAS :Produit contrôlé<p>Stability Air Sensitive, Light Sensitive, Moisture Sensitive, Temperature Sensitive<br>Applications N-Acetyl-4-benzoquinone Imine (NAPQI) is a toxic metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). N-Acetyl-4-benzoquinone Imine can react with cysteine residues of hepatic proteins to yield Acetaminophen-cysteine (A161255) (4).<br>References (1) Jaeschke, H., et al.: Toxicol. Sci., 89, 31 (2006) (2) O’Malley G. F., et al.: J Med Toxicol. 11, 317 (2015)(3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(4) Frey, S. M., et al.: J Med Toxicol. 11, 218 (2015)<br></p>Formule :C8H7NO2Couleur et forme :NeatMasse moléculaire :149.152-Butyl-6-methoxynaphthalene
CAS :Produit contrôlé<p>Applications 2-Butyl-6-methoxynaphthalene is an impurity of Nabumetone (N200500), an anti-inflammatory and antibacterial agent.<br>References Najera, C., et al.: Adv. Syn. Cat., 346, 1798 (2004); Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006)<br></p>Formule :C15H18OCouleur et forme :White To GreyMasse moléculaire :214.34-Acetaminophen-d3 Sulfate
CAS :Produit contrôlé<p>Applications 4-Acetaminophen-d3 Sulfate is deuterium labeled metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent (1,2,3).<br>References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961) (2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)<br></p>Formule :C82H3H6NO5SCouleur et forme :White To Off-WhiteMasse moléculaire :234.241-(2,3-Dimethylphenyl)ethyl Chloride
CAS :Produit contrôlé<p>Applications 1-(2,3-Dimethylphenyl)ethyl Chloride is an impurity of Medetomidine (M203250), an α2-Adrenergic agonist. Sedative; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987), Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987), Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988), Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996),<br></p>Formule :C10H13ClCouleur et forme :Clear Colourless To Dark BrownMasse moléculaire :168.66(R)-Apomorphine b-D-Glucuronide
Produit contrôléFormule :C23H25NO8Couleur et forme :WhiteMasse moléculaire :443.45N-(2-ACETYLPHENYL)-4-METHYLPENTANAMIDE
CAS :Degré de pureté :95.0%Masse moléculaire :233.311004638671882,2',5'-Trichloroacetophenone
CAS :Produit contrôlé<p>Applications 2,2',5'-Trichloroacetophenone is a useful research chemical for organic synthesis and other chemical processes.<br>References Xu, L., et al.: Chem. Res. Chin. Univ., 24, 299 (2008); Song, W., et al.: MedChemComm, 7, 1441 (2016)<br></p>Formule :C8H5Cl3OCouleur et forme :NeatMasse moléculaire :223.48Niflumic Acid
CAS :Produit contrôlé<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Formule :C13H9F3N2O2Couleur et forme :Light YellowMasse moléculaire :282.223-Methylbenzophenone
CAS :<p>Applications 3-Methylbenzophenone (cas# 643-65-2) is a useful research chemical.<br></p>Formule :C14H12OCouleur et forme :NeatMasse moléculaire :196.244-Hydroxydiphenylamine
CAS :Produit contrôléFormule :C12H11NOCouleur et forme :NeatMasse moléculaire :185.228-Methylquinoline
CAS :<p>Applications 8-Methylquinoline is used in QSAR treatment of mutagenicity and cytotoxicity of quinolines.<br>References Smith, C. J., et al.: Mutat. Res., Fund. Mol. Mech. Mut., 379, 167 (1997)<br></p>Formule :C10H9NCouleur et forme :Light Yellow LiquidMasse moléculaire :143.185rac-Ibuprofen Amide
CAS :Produit contrôlé<p>Impurity Ibuprofen EP Impurity C<br>Applications An impurity of Ibuprofen (I140000).<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Sochor, J., et al.: J. Pharm. Biomed. Anal., 13, 899 (1995),<br></p>Formule :C13H19NOCouleur et forme :WhiteMasse moléculaire :205.30Acetanilide (Acetylaniline)
CAS :Produit contrôlé<p>Impurity Paracetamol EP Impurity D<br>Applications Acetanilide (Acetylaniline) the first aniline derivative found to possess analgesic and antipyretic properties (1,2). It is also an impurity of Acetaminophen (A161220).<br>References (1) Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010) (2) Chang, C., et al.: J. Nat. Prod., 73, 229 (2010)<br></p>Formule :C8H9NOCouleur et forme :White To Light BrownMasse moléculaire :135.16(S)-Ketorolac
CAS :Produit contrôlé<p>Applications (S)-Ketorolac is the S-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.<br>References Rooks, W.H., et al.: Agents Actions, 12, 684 (1982), Guzman, A., et al.: J. Med. Chem., 29, 589 (1986), McQuary, H.J., et al.: Clin. Pharmacol. Ther., 39, 89 (1986),<br></p>Formule :C15H13NO3Couleur et forme :NeatMasse moléculaire :255.271-(4-(Phenylethynyl)phenyl)ethan-1-one
CAS :Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :220.27099613-Hydroxy Medetomidine
CAS :Produit contrôlé<p>Applications A metabolite of Medetomidine (M203250).<br>References Salonen, J.S., et al.: Xenobiotica, 20, 471 (1990),<br></p>Formule :C13H16N2OCouleur et forme :NeatMasse moléculaire :216.28Ketoprofen 1,4-Sorbitan Ester
Produit contrôlé<p>Applications Ketoprofen 1,4-Sorbitan Ester is a derivative of Ketoprofen (K200800), an anti-inflammatory; analgesic.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),<br></p>Formule :C22H24O7Couleur et forme :Off-WhiteMasse moléculaire :400.42Hydroxy Carisoprodol (mixture of diastereomers)
CAS :Produit contrôlé<p>Applications Hydroxy Carisoprodol is the metabolite of Carisoprodol (C183580) in equine urine and serum.<br>References Kintz, P., et al.: J. Anal. Toxicol., 17, 408 (1993), Olsen, H., et al.: Ther. Drug Monit., 16, 337 (1994), Reeves, R., et al.: J. Addict. Diseas., 18, 51 (1999),<br></p>Formule :C12H24N2O5Couleur et forme :NeatMasse moléculaire :276.33(-)-(3S)-3-Hydroxy Quinine
CAS :Produit contrôléFormule :C20H24N2O3Couleur et forme :NeatMasse moléculaire :340.42Metaxalone-d6
CAS :Produit contrôlé<p>Applications It is a muscle relaxant used to relax muscles and relieve pain.<br></p>Formule :C122H6H9NO3Couleur et forme :NeatMasse moléculaire :227.29Bornyl Acetate (Mixture of Diastereomers)
CAS :<p>Applications Bornyl Acetate (Mixture of Diastereomers) is a monoterpene ester, and also the main, natural constituent of valerian root oil. Bornyl acetate also has analgesic and anti-inflammatory properties.<br>References Buchbauer, G., et al.: Die Pharm., 47, 620 (1992); Oh, H., et al.: Appl. Micro., 15, 777 (1967); Wu, X., et al.: J. Chinese Med. Mat., 27, 438 (2004)<br></p>Formule :C12H20O2Couleur et forme :NeatMasse moléculaire :196.29Acemetacin
CAS :Produit contrôlé<p>Applications Acemetacin is a non-steroidal anti-inflammatory agent and used to treat rheumatic disease and other musculoskeletal disorders (1,2).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Jacobi, H. and Dell, H. D.: Arzneimittelforschung 30, 1398 (1980) (2) Moore, R. A., et al.: Cochrane Database Syst Rev. 8,CD007589 (2009)<br></p>Formule :C21H18ClNO6Couleur et forme :YellowMasse moléculaire :415.82rac Ketoprofen Amide
CAS :Produit contrôlé<p>Applications An amide of Ketoprofen (K200800) with anti-inflammatory properties.<br>References Spickett, R.G.W. et al.: Eur. J. Med. Chem., 11, 7 (1976); Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981);<br></p>Formule :C16H15NO2Couleur et forme :WhiteMasse moléculaire :253.304'-Isobutylacetophenone
CAS :Produit contrôlé<p>Impurity Ibuprofen EP Impurity E<br>Applications 4'-Isobutylacetophenone (Ibuprofen EP Impurity E) is a degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reynolds, D., et al.: Pharm. Technol., 26, 48 (2002), Wasylaschuk, W., et al.: J. Pharm. Sci., 96, 106 (2007),<br></p>Formule :C12H16OCouleur et forme :Colourless To Light YellowMasse moléculaire :176.25S-Methyl-d3-thioacetaminophen
CAS :Produit contrôlé<p>Applications S-Methyl-d3-thioacetaminophen is deuterium labeled S-Methyl-3-thioacetaminophen (M330610), a metabolite of Acetaminophen (A161220). Acetaminophen is an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formule :C92H3H8NO2SCouleur et forme :NeatMasse moléculaire :200.27rac-4’-Methyl Ketoprofen
CAS :<p>Impurity Ketoprofen EP Impurity D; Ketoprofen USP Related Compound A<br>Applications rac-4’-Methyl Ketoprofen (Ketoprofen EP Impurity D; Ketoprofen USP Related Compound A) is an impurity of Ketoprofen (K200800).<br>References Pietta, P. et al.: J. Chrom., 387, 525 (1987); Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981);<br></p>Formule :C17H16O3Couleur et forme :BeigeMasse moléculaire :268.31rac Ketoprofen-d3
CAS :Produit contrôlé<p>Applications rac Ketoprofen-d3 is the labeled analogue of rac Ketoprofen (K200800), an anti-inflammatory; analgesic. rac Ketoprofen-d3 has been used in the preparation of labeled human drug metabolites.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990); Poraj-Kobielska, M., et. al.: J. Labelled Compd. Rad., 56, 513 (2013)<br></p>Formule :C162H3H11O3Couleur et forme :NeatMasse moléculaire :257.30TEMPO
CAS :Produit contrôlé<p>Applications TEMPO is a stable radical prepared through the oxidation of 2,2,6,6-tetramethylpiperidine. TEMPO has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy. TEMPO can also be used as a mediator in free radical polymerization.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Seaton, T.A. et al.: Brain Res., 777, 110 (1997); Tanielyan, S.K. et al.: Top. Catal., 55, 556 (2012); Wolinska-Grabczyk, A. et al.: Polymer, 46, 2461 (2005); Keoshkerian, B. et al.: Polym. Prep., 35, 675 (1994);<br></p>Formule :C9H18NOCouleur et forme :NeatMasse moléculaire :156.25rac-Naproxen
CAS :<p>Applications An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)<br></p>Formule :C14H14O3Couleur et forme :NeatMasse moléculaire :230.26rac Ketorolac Acyl-β-D-glucuronide (Mixture of Diastereomers)
CAS :Produit contrôlé<p>Stability Moisture Sensitive, Light Sensitive<br>Applications A metabolite of Ketorolac.<br>References Mroszczak, E., et al.: Drug Metab. Dispos., 15, 618 (1987), Brocks, D., et al.: Clin. Pharmacokinet., 23, 415 (1992), Vakily, M., et al.: Pharm. Res., 12, 1652 (1995), Gillis, J., et al.: Drugs, 53, 139 (1997),<br></p>Formule :C21H21NO9Couleur et forme :NeatMasse moléculaire :431.39Acetaminophen Acetate (Acetaminophen Impurity)
CAS :<p>Impurity Paracetamol EP Impurity H/ Acetaminophen impurity H<br>Applications Acetaminophen Acetate is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formule :C10H11NO3Couleur et forme :White To Off-WhiteMasse moléculaire :193.20Phenacetin
CAS :Produit contrôlé<p>Applications Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959), Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983),<br></p>Formule :C10H13NO2Couleur et forme :WhiteMasse moléculaire :179.22Metaxalone
CAS :Produit contrôléFormule :C12H15NO3Couleur et forme :Off WhiteMasse moléculaire :221.25Phenacetin-d3
CAS :Produit contrôlé<p>Applications Phenacetin-d3 is the labeled analogue of Phenacetin (P294580), an analgesic, antipyretic; component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959); Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983)<br></p>Formule :C10H10D3NO2Couleur et forme :NeatMasse moléculaire :182.232-Chloronicotinic Acid
CAS :Produit contrôlé<p>Applications 2-Chloronicotinic Acid is used in the preparation of 4-thiazolidinone derivatives and Schiff bases displaying antimicrobial activity.<br>References Patel, N. et al.: Saudi Pharm. J., 18, 129 (2010); Patel, N. et al.: J. Sci. Islam Repub. Iran., 21, 121 (2010);<br></p>Formule :C6H4ClNO2Couleur et forme :NeatMasse moléculaire :157.553'-Chloroacetophenone
CAS :Degré de pureté :97.0%Couleur et forme :Liquid, ClearMasse moléculaire :154.58999633789062rac Ketoprofen PEG 400 Ester
Produit contrôlé<p>Applications rac Ketoprofen PEG 400 Ester is an impurity of rac Ketoprofen (K200800) which is anti-inflammatory.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990)<br></p>Formule :C18H18O4Couleur et forme :Colourless To Light YellowMasse moléculaire :n/a
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