Dérivés du Benzimidazole et de l’Imidazole
Le benzimidazole est un composé constitué d’un noyau benzénique fusionné à un noyau imidazole, une structure à cinq membres contenant deux atomes d’azote. Les dérivés du benzimidazole, comme l’albendazole, sont connus pour leur activité antiparasitaire et antifongique, utilisés dans le traitement des infections parasitaires et de certaines maladies parasitaires chez les animaux et les humains. L’imidazole, quant à lui, est une structure à cinq membres avec deux atomes d’azote, présente dans divers composés biologiquement actifs. Les dérivés de l’imidazole, comme le métronidazole, possèdent des propriétés antimicrobiennes et antiparasitaires. Ces composés sont également utilisés dans l’industrie pharmaceutique pour le traitement des infections bactériennes, des maladies parasitaires et de certaines infections fongiques, ainsi qu’en chimie organique comme catalyseurs.
Chez CymitQuimica, nous proposons des benzimidazoles et des imidazoles de haute pureté pour la recherche en chimie médicinale, pharmacologie et biotechnologie.
10345 produits trouvés pour "Dérivés du Benzimidazole et de l’Imidazole"
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3,3',5,5'-Tetra(1H-imidazol-1-yl)-1,1'-biphenyl
CAS :Degré de pureté :98%Masse moléculaire :418.4639892578125Ref: 10-F987646
1gÀ demander5gÀ demander5mg80,00€10mg102,00€25mg211,00€50mg362,00€100mgÀ demander250mgÀ demander1-(5-Bromopyrimidin-2-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS :Degré de pureté :95.0%Masse moléculaire :291.10800170898442-(3-Bromophenyl)-1-phenyl-1H-benzoimidazole
CAS :Degré de pureté :95.0%Masse moléculaire :349.2309875488281(S)-(-)-Pantoprazole Sodium Salt
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications The S-enantiomer of Pantoprazole (P183000).<br>References Simon, W.A., et al.: Biochem. Pharmacol., 39, 1799 (1990),<br></p>Formule :C16H14F2N3O4S·NaCouleur et forme :NeatMasse moléculaire :405.35N-(3-(1H-imidazol-1-yl)propyl)-4-ethoxybenzo[d]thiazol-2-amine
CAS :Degré de pureté :95.0%Masse moléculaire :302.39999389648441-Phenyl-1H-benzoimidazole-5-carboxylic acid
CAS :Degré de pureté :95.0%Masse moléculaire :238.24600219726562Atropine-N-oxide Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Atropine-N-oxide Hydrochloride is an alkaloid. A neuroprotective compound with potential therapeutic efficacy.<br>References Beraki, S., et al.: PLoS One, 8, 69233 (2013); Polonovski, M., et al: Compt. rend., 180, 1755 (1925)<br></p>Formule :C17H23NO4·ClHCouleur et forme :NeatMasse moléculaire :341.83(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol
CAS :Produit contrôlé<p>Applications (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-Butanediol (cas# 133775-25-4) is a useful research chemical.<br></p>Formule :C12H13F2N3O2Couleur et forme :NeatMasse moléculaire :269.25Lamotrigine 3,3-Dimer
CAS :Produit contrôlé<p>Applications Lamotrigine 3,3-Dimer is a dimer impurity of the anticonvulsant Lamotrigine (L173250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C19H14Cl4N10Couleur et forme :NeatMasse moléculaire :524.195-(4'-METHYL-1,1'-BIPHEN-2-YL)-1H-TETRAZOLE
CAS :Degré de pureté :95%Masse moléculaire :236.27799987792975-(4-(Benzyloxy)-3-fluorophenyl)oxazole
CAS :Degré de pureté :98%Masse moléculaire :269.27499389648447-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide
CAS :Produit contrôlé<p>Applications 7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator.<br>References Rodgers, T. et al.: J. Med. Chem., 20, 591 (1977); Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);<br></p>Formule :C19H22BrNO4S2Couleur et forme :NeatMasse moléculaire :472.422,2'-(OXYDIMETHANEDIYL)BIS(5-NITRO-1H-BENZIMIDAZOLE)
CAS :Degré de pureté :95.0%Masse moléculaire :368.30899047851565-(3-METHOXYBENZYL)-1H-INDAZOL-3-AMINE
CAS :Degré de pureté :95.0%Masse moléculaire :253.30499267578125SODIUM 5-METHYL-1,3-OXAZOLE-2-CARBOXYLATE
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :149.08099365234375Ronidazole
CAS :<p>Applications Antimicrobial.<br>References Yamada, R., et al.: Biosci. Biotechnol. Biochem., 70, 54 (2006), Mohamed, R., et al.: J. Agric. Food Chem., 56, 3500 (2008), Leitsch, D., et al.: Mol. Microbiol., 72, 518 (2009),<br></p>Formule :C6H8N4O4Couleur et forme :Light YellowMasse moléculaire :200.155-(1-methyl-1H-benzimidazol-2-yl)-2-furaldehyde
CAS :Degré de pureté :95.0%Masse moléculaire :226.235000610351561-(2-Trifluoromethylphenyl)imidazole
CAS :Formule :C10H7F3N2Degré de pureté :98.0%Couleur et forme :SolidMasse moléculaire :212.1755-Nitro-1H-imidazole-1-ethanol
CAS :Produit contrôlé<p>Applications 5-Nitro-1H-imidazole-1-ethanol (cas# 5006-68-8) is a compound useful in organic synthesis.<br></p>Formule :C5H7N3O3Couleur et forme :NeatMasse moléculaire :157.132-[(2,4-Dichlorophenoxy)methyl]-1H-benzimidazole
CAS :Degré de pureté :95.0%Masse moléculaire :293.1499938964844(2S)-3-methyl-2-(N-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}pentanamido)butanoic acid
CAS :Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :435.52801513671875Neticonazole
CAS :<p>Neticonazole has anti-infective and anti-cancer effects, inhibits exosome secretion, and can be used to study Candida albicans infection of the skin.</p>Formule :C17H22N2OSDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :302.43(R)-4-Isopropyl-5,5-diphenyloxazolidin-2-one
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :281.3550109863281Paclobutrazol
CAS :<p>Applications Paclobutrazol is a triazole fungicide used as an plant growth retardant in inhibiting gibberellin biosynthesis. Paclobutrazol is used in cannabis testing kits as a component of pesticide mixes (P698235).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hou, X., et al.: Food. Chem., 138, 1198 (2013); Wu, C.W., et al.: Environ. Sci. Technol., 47, 843 (2013);<br></p>Formule :C15H20ClN3OCouleur et forme :WhiteMasse moléculaire :293.79Ethyl 5-benzyloxy-1H-indazole-3-carboxylate
CAS :Degré de pureté :95%Masse moléculaire :296.325988769531256-ethyl-N-[3-(1H-imidazol-1-yl)propyl]-1,3-benzothiazol-2-amine
CAS :Degré de pureté :95.0%Masse moléculaire :286.39999389648443-Cyclobutyl-1H-indazole
CAS :Degré de pureté :>95%Couleur et forme :Liquid, No data available.Masse moléculaire :172.23100280761725-Amino-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
CAS :Formule :C14H19N3O2Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :261.325Modafinil Carboxylate
CAS :Produit contrôléFormule :C15H14O3SCouleur et forme :NeatMasse moléculaire :274.33Albendazole Sulfoxide
CAS :<p>Impurity Albendazole EP Impurity B<br>Applications Albendazole Sulfoxide (Albendazole EP Impurity B) is a metabolite of Albendazole, an anthelmintic.<br>References Dominguez, L., et al.: Farmaco, 50, 697 (1995), De Laurentis, N., et al.: Pharm. Pharmacol Lett., 6, 2: 51 (1996)<br></p>Formule :C12H15N3O3SCouleur et forme :White To BrownMasse moléculaire :281.333-(2-Isopropyl-imidazol-1-yl)-propionic acid
CAS :Formule :C9H14N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :182.2232-(2-Phenyl-2H-tetrazol-5-yl)pyridine
CAS :Degré de pureté :95.0%Masse moléculaire :223.23899841308594Apoatropine Hydrochloride
CAS :<p>Applications Apoatropine is an alkaloid derivative with the potential to be an antibacterial.<br>References Cherkaoui, S. et al.: Electrophor., 19, 2900 (1998); Marrero-Ponce, Y. et al.: Bioorg. Med. Chem., 13, 2881 (2005);<br></p>Formule :C17H21NO2·ClHCouleur et forme :White To Off-WhiteMasse moléculaire :307.822,4-Diiodo-1H-imidazole
CAS :Degré de pureté :97.0%Couleur et forme :Solid, Off-white to pale yellow solidMasse moléculaire :319.872009277343758-Chloro-1-methyl-6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepine
CAS :Produit contrôlé<p>Impurity Midazolam EP Impurity G<br>Applications 8-Chloro-1-methyl-6-phenyl-4H-Imidazo[1,5-a][1,4]benzodiazepine is an impurity of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984); Lahat, E., et al.: Br. Med. J., 321, 83 (2000);<br></p>Formule :C18H14ClN3Couleur et forme :Brown SolidMasse moléculaire :307.78(E)-2-(4-(1H-Imidazol-4-yl)styryl)-1H-indene-1,3(2H)-dione
CAS :Degré de pureté :95.0%Masse moléculaire :314.3439941406252-Phenyloxazole-5-carboxylic acid
CAS :Formule :C10H7NO3Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :189.17Tofenacin Hydrochloride Salt
CAS :Produit contrôlé<p>Applications A metabolite of Orphenadrine (O695300). An antidepressant prodrug. Ondansetron USP Related Compound C.<br>References Watkins, P., et al.: J. Biol. Chem., 261, 6264 (1986), McNeil, C., et al.: Biochem. Pharmacol., 51, 15 (1996), Hiessbock, R., et al.: J. Med. Chem., 42, 1921 (1999),<br></p>Formule :C17H21NO·ClHCouleur et forme :NeatMasse moléculaire :291.821-(3-chloro-2-methylphenyl)-5-phenyl-2,3-dihydro-1H-imidazole-2-thione
CAS :Degré de pureté :98%Masse moléculaire :300.799987792968754-CYCLOPROPYL-1H-IMIDAZOLE
CAS :Formule :C6H8N2Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :108.1442-(4-Bromo-phenyl)-1 H -benzoimidazol-5-ylamine
CAS :Degré de pureté :95.0%Masse moléculaire :288.148010253906255-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole
CAS :Degré de pureté :97%Masse moléculaire :478.5989990234375Ref: 10-F692709
1gÀ demander5gÀ demander1kgÀ demander25gÀ demander100gÀ demander500gÀ demander100mgÀ demander250mgÀ demander2-(2-fluorophenyl)-1H-1,3-benzodiazole
CAS :Degré de pureté :95.0%Masse moléculaire :212.2270050048828Ethyl 5-(4'-Bromophenyl)-1,3-oxazole-4-carboxylate
CAS :Degré de pureté :97.0%Couleur et forme :SolidMasse moléculaire :296.11999511718754-Chloro-6-nitro-1,3-dihydro-2H-benzo[d]imidazol-2-one
CAS :Degré de pureté :98%Masse moléculaire :213.58000183105475-(4-Methoxyphenyl)-2,3-diphenyl-2H-tetrazol-3-ium chloride
CAS :Degré de pureté :98%Masse moléculaire :364.8299865722656Methylthiazolyldiphenyl-tetrazolium bromide
CAS :Degré de pureté :98.0%Couleur et forme :SolidMasse moléculaire :414.32998657226561-(pyrrolidin-3-yl)-1H-1,3-benzodiazole dihydrochloride
CAS :Degré de pureté :95.0%Masse moléculaire :260.1600036621094Nimorazole
CAS :Produit contrôlé<p>Applications Nimorazole is an antimicrobial with activity against anaerobic bacteria and protozoa.<br>References Ratnaparkhi, M.P., et al.: Res. J. Pharma. BIol. Chem. Sci., 3, 303 (2012); Toustrup, K., et al.: Radiotherap. Oncol., 102, 122 (2012);<br></p>Formule :C9H14N4O3Couleur et forme :NeatMasse moléculaire :226.232-Nitroaniline
CAS :Produit contrôlé<p>Impurity Albendazole Impurity 4<br>Applications 2-Nitroaniline, is the main precursor to phenylenediamines, which are converted to benzimidazoles, a family of heterocycles that are key components in pharmaceuticals. Albendazole Impurity 4<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Booth, G.,et al.: Ull. Encyc. Indust. Chem. (2007);<br></p>Formule :C6H6N2O2Couleur et forme :NeatMasse moléculaire :138.12Tinidazole-d5
CAS :Produit contrôlé<p>Applications Labelled Tinidazole. Antiprotozoal (Trichomonas, Giardia); antiamebic; antibacterial.<br>References Miller, M.W., et al.: J. Med. Chem., 13, 849 (1970), Oderdea, G., et al.: Gut, 33, 1328 (1992),<br></p>Formule :C8H8D5N3O4SCouleur et forme :NeatMasse moléculaire :252.32-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine, Hydrochloride
CAS :Produit contrôléFormule :C9H9ClF3NO·ClHCouleur et forme :NeatMasse moléculaire :276.085-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methylbenzoic acid
CAS :Degré de pureté :97%Masse moléculaire :260.268005371093752-(2-Cyclopropyl-6-fluoro-1H-1,3-benzodiazol-1-yl)acetic acid
CAS :Masse moléculaire :234.229995727539062-(1H-INDAZOL-1-YL)THIAZOLE-4-CARBOXYLIC ACID
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :245.25999450683594Omeprazole-d3
CAS :Produit contrôlé<p>Applications Labelled Omeprazole, which binds covalently to proton pump, it inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formule :C172H3H16N3O3SCouleur et forme :NeatMasse moléculaire :348.43Modafinil-d10 Carboxylate
CAS :Produit contrôlé<p>Applications A metabolite of Modafinil, a central nervous system vigilance promoting agent, which possesses neuroprotective properties.<br>References Duteil, J., et al.: Eur. J. Pharmacol., 180, 49 (1990), Wong, Y., et al.: J. Clin. Pharmacol., 317, 30 (1999), Robertson, P., et al.: Drug Disp., 42, 123 (2003)<br></p>Formule :C15H4D10O3SCouleur et forme :NeatMasse moléculaire :284.43-(2-Amino-2-oxoethyl)-5-methylhexanoic Acid
CAS :Formule :C9H17NO3Couleur et forme :NeatMasse moléculaire :187.243-Dechloro-4-chloro Lamotrigine
CAS :Produit contrôlé<p>Impurity Lamotrigine EP Impurity G<br>Applications 3-Dechloro-4-chloro Lamotrigine (Lamotrigine EP Impurity G) is a potential impurity of Lamotrigine (L173250).<br>References Rees, R., et al.: J. Med. Chem., 15, 859 (1972), McNamara, J., et al.: Nature, 399, A15 (1999),<br></p>Formule :C9H7Cl2N5Couleur et forme :NeatMasse moléculaire :256.09N-(3-(1H-imidazol-1-yl)propyl)-1-(4-fluorophenyl)-2,2-dimethylcyclopropane-1-carboxamide
CAS :Degré de pureté :98%Masse moléculaire :315.39199829101564-(5-Nitro-1H-benzo[d]imidazol-2-yl)aniline
CAS :Degré de pureté :95.0%Masse moléculaire :254.24899291992188(R)-5-Hydroxymethyl tolterodine
CAS :<p>(R)-5-Hydroxymethyl tolterodine is a prodrug that is metabolized by cytochrome P450 3A4 (CYP3A4) in the liver to its active form, tolterodine. This drug can be used as an alternative for gabapentin in the treatment of detrusor muscle overactivity associated with neurogenic bladder dysfunction. The pharmacokinetic properties of (R)-5-hydroxymethyl tolterodine are similar to those of gabapentin, including the elimination half-life and volume of distribution. However, unlike gabapentin, which has been shown to increase the glomerular filtration rate (GFR) and renal blood flow, there is no evidence that this drug has any effect on GFR or renal blood flow. There is also no evidence that (R)-5-hydroxymethyl tolterodine causes any symptoms that may be attributed to</p>Formule :C22H31NO2Degré de pureté :Min. 98 Area-%Couleur et forme :Off-White PowderMasse moléculaire :341.49 g/mol2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole
CAS :<p>2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole is a protonated sulfonamide that is used as an analytical method to detect the presence of other drugs in human liver tissue. It has been shown to inhibit the activity of cytochrome P450 3A4 (CYP3A4), one of the enzymes responsible for metabolizing many drugs. Bromoenol lactone and powder diffraction spectrum are two additional analytical methods that can be used to detect 2-[([(4-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole.</p>Formule :C18H21N3O4SDegré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :375.44 g/mol(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
CAS :<p>(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a drug used to treat depression. It is an antidepressant drug that inhibits the reuptake of serotonin and norepinephrine in the brain by blocking their transport into the nerve cells. The drug acts as a weak inhibitor of monoamine oxidase (MAO). It also has an effect on bladder function. This compound is synthesized from 1-phenyl-2,5-dihydrothiazole by way of a sequence of reactions that includes the formation of an amine salt via reaction with phosphorus pentoxide and chloroacetic acid followed by conversion to the chloride with thionyl chloride.</p>Formule :C15H15NDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :209.29 g/mol1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine
CAS :<p>1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine is an analytical standard and a drug product. It is a synthetic compound that has been shown to have pharmacological effects similar to those of the analgesic or opioid drugs. 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine can be used as an impurity standard for HPLC analyses as well as metabolic studies. This compound is also known to have potential interactions with other drugs.</p>Formule :C24H27NO3Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :377.48 g/mol3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one
CAS :<p>3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one is a triazine derivative that is used as an analytical reagent and intermediate. It has been used as a wastewater analysis method to measure the concentration of carbamazepine. 3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one has also been shown to be useful in developing analytical methods for clinical trials. 3DCTKP has also been used to test the matrix effect of carbamazepine by analyzing it in different matrices such as water and human plasma.</p>Formule :C9H6Cl2N4ODegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :257.08 g/molN-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide
CAS :<p>N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide is a pharmaceutical dosage form that is titrated to achieve the desired therapeutic effect. It is used to treat epilepsy and bipolar disorder. Lamotrigine binds to sodium channels in nerve cells and blocks their opening. This prevents the influx of sodium ions that are necessary for neuronal transmission. Lamotrigine has been shown to have an anticonvulsant effect by reducing the frequency of seizures in patients with epilepsy.</p>Formule :C16H9Cl4N5ODegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :429.09 g/molAlbendazole sulfoxide
CAS :<p>Albendazole sulfoxide is a sulfoxide of albendazole. The molecular docking analysis of the two molecules showed that the sulfoxide group is located in the same position as the hydroxyl group on albendazole. It has been shown that this replacement of hydroxyl with a sulfoxide group increases the solubility and stability of albendazole, which may be due to hydrogen bonding interactions between these groups. Albendazole sulfoxide has been shown to be an effective treatment for infections caused by parasites such as helminths. However, it should not be used in combination with drugs that are metabolized by cytochrome P450 enzymes because it can inhibit their activity.</p>Formule :C12H15N3O3SDegré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :281.33 g/mol5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole
CAS :<p>5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole is a natural product. It is an impurity in the drug development process and may be present as an analytical marker for impurities. 5-Methoxy-2-[(3,5-dimethylpyridinium)methyl]sulfinyl]-1Hbenzimidazole is used as a pharmacopoeia standard and can be synthesized on request.</p>Formule :C16H17N3O2SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :315.39 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole
CAS :<p>Omeprazole is a drug that belongs to the class of benzimidazole compounds. It is an inhibitor of gastric acid secretion in the stomach, reducing the production of hydrochloric acid and pepsin. Omeprazole has been shown to have greater chemical stability than other proton pump inhibitors (PPIs), with a higher solubility in water and a longer shelf life. Omeprazole also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. Omeprazole also exhibits pharmacokinetic properties that are different from other PPIs. Omeprazole is rapidly absorbed following oral administration and has a high bioavailability, which can be attributed to its hydroxyl group. This hydroxyl group allows for esomeprazole (a prodrug) to be formed by hydrolysis in the gut or liver, increasing omeprazole's absorption and bioavailability.</p>Formule :C17H19N3O2SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :329.42 g/mol4-Desmethoxy omeprazole sulfide
CAS :<p>4-Desmethoxy omeprazole sulfide is a metabolite of omeprazole, a drug that is used to treat ulcers and gastroesophageal reflux disease. 4-Desmethoxy omeprazole sulfide is not an impurity in the production of omeprazole, but is present as a natural component of omeprazole. This compound has been shown to be an impurity standard for HPLC analysis. The pharmacopoeia defines 4-desmethoxy omeprazole sulfide as an API impurity in drug products. It is also being studied for its potential use in drug development and research and development.</p>Formule :C16H17N3OSDegré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :299.39 g/molN-(2-Phenethyl)benzamide
CAS :<p>N-(2-Phenethyl)benzamide (NPEB) is a molecule that belongs to the group of reactive molecules. It has been shown to be toxic to gram-positive bacteria, such as Staphylococcus aureus and Bacillus subtilis, but not gram-negative bacteria such as Escherichia coli. NPEB also has been shown to have locomotor activity in animals, which may be due to its ability to inhibit the mitochondrial electron transport chain and inhibit ATP production. NPEB's biological properties are well characterized. FTIR spectroscopy showed that this molecule has an amide functional group and is a small molecule with a molecular weight of 176.4 g/mol. This molecule was also found to be able to bind to mitochondria in animals.</p>Formule :C15H15NODegré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :225.29 g/molDi-2-thienylmethanone
CAS :<p>Di-2-thienylmethanone is a pyrazole with an activation energy of about 10.5 kcal/mol. It has been found to be toxic and can cause cell lysis. This molecule has been used in the synthesis of a number of drugs, including thiopental, a barbiturate that is used as an anaesthetic. Di-2-thienylmethanone is also the precursor for the synthesis of fluoroquinolones, which are potent antibacterial agents. The Friedel-Crafts reaction is one way this molecule is synthesized, and it involves the addition of an alkyl halide to an unsaturated double bond. This reaction is named after Charles Friedel and James Crafts who first discovered it in 1877.</p>Formule :C9H6OS2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :194.28 g/molOmeprazole impurity F and G
CAS :<p>Omeprazole is a proton pump inhibitor that inhibits the H+/K+-ATPase enzyme in gastric parietal cells. Omeprazole impurity F and G are metabolites of omeprazole. Omeprazole impurity F is a metabolite of omeprazole that forms by oxidation of the methylthio group in omeprazole to form a sulfoxide. Omeprazole impurity G is formed by hydrolysis of the methylthio group in omeprazole to form an alcohol. The purity of this product is high and can be custom synthesized based on customer's needs. It is also available as an HPLC standard or as an API impurity for use in metabolism studies.</p>Formule :C16H13N3O2SDegré de pureté :Min. 95%Couleur et forme :Red PowderMasse moléculaire :311.36 g/mol2-Mercaptobenzimidazole
CAS :<p>2-Mercaptobenzimidazole is a chemical compound that can be used for the treatment of infectious diseases. It has been shown to have antioxidative properties and inhibit the growth of bacteria. 2-Mercaptobenzimidazole also has an effect on human serum, which may be due to its ability to bind with proteins in serum and form hydrogen bonds. 2-Mercaptobenzimidazole is stable at high temperatures and has been shown as an effective antimicrobial agent against gram positive and gram negative bacteria.</p>Formule :C7H6N2SDegré de pureté :Min. 99 Area-%Couleur et forme :White/Off-White SolidMasse moléculaire :150.19 g/molPantoprazole sulfide N-oxide
CAS :<p>Pantoprazole sulfide N-oxide is a metabolite of pantoprazole, which is a proton pump inhibitor used to reduce stomach acid production. Pantoprazole sulfide N-oxide is an impurity in pantoprazole that can be detected by HPLC. It has been shown to have about the same biological activity as pantoprazole when given orally.</p>Formule :C16H15F2N3O4SDegré de pureté :Min. 95%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :383.37 g/molPantoprazole sodium hydrate - Mixture of impurities D and F
CAS :<p>Pantoprazole sodium hydrate is a custom synthesis that is used as a drug product. The CAS number for this compound is 624742-53-6. This compound has the following impurities: D and F. Pantoprazole sodium hydrate has been shown to be metabolized in vitro by human liver microsomes to its metabolites, including the following: (1) pantoprazol acid, (2) 4-hydroxypantoprazol acid, (3) 4-hydroxyisoxazole acid, and (4) 5-(4-hydroxyphenyl)-2H-1,2-benzoxazin-3(4H)-one. The metabolite 4-hydroxypantoprazol acid has been found to be pharmacologically active in animal models of gastric ulceration and healing.</p>Formule :C17H17F2N3O4SDegré de pureté :Min. 95%Couleur et forme :Off-white to yellow powder.Masse moléculaire :397.4 g/mol5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one (donepezil impurity)
CAS :<p>5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one (donepezil impurity) is an analytical standard used as a reference in HPLC assays for donepezil. It is also a metabolite of donepezil and has been found to have pharmacological activity similar to that of the parent compound. This impurity is present in donepezil drug products at levels up to 0.5%.</p>Formule :C17H21NO3Degré de pureté :Min. 95%Masse moléculaire :287.35 g/molLansoprazole N-oxide
CAS :<p>Lansoprazole N-oxide is a prodrug that is converted to lansoprazole sulfone in vivo. Lansoprazole N-oxide is used as a diluent in chromatographic experiments. It has been shown to be more sensitive than the parent compound, lansoprazole, for the diagnosis of reflux oesophagitis. Lansoprazole N-oxide also has a validation wavelength of 240 nm and can be detected by liquid chromatography. The active form of lansoprazole, lansoprazole sulfone, can be detected by gas chromatography mass spectrometry (GCMS).</p>Formule :C16H14F3N3O3SDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :385.36 g/molMethyl 2,2-dithienylglycolate
CAS :<p>Intermediate for tiotropium bromide synthesis</p>Formule :C11H10O3S2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :254.33 g/mol10,11-Dihydroxy-d10 Carbamazepine
Produit contrôlé<p>10,11-Dihydroxy-d10 Carbamazepine is a drug product that is used as an analytical reference standard. It is natural and synthetic impurity in the API (active pharmaceutical ingredient) Carbamazepine. The CAS number for 10,11-Dihydroxy-d10 Carbamazepine is 513-81-5. This compound has been synthesized by custom synthesis and is an impurity standard for HPLC analysis of carbamazepine. 10,11-Dihydroxy-d10 Carbamazepine is also a research and development chemical for the drug development industry. It has been classified as a niche chemical due to its high purity and pharmacopoeia grade.</p>Degré de pureté :Min. 95%2-Hydroxybenzimidazole
CAS :<p>2-Hydroxybenzimidazole is a benzimidazole compound that is used in the treatment of nervous system diseases. It has been shown to have anti-inflammatory properties and can be used in the treatment of syncytial virus infection. 2-Hydroxybenzimidazole inhibits the production of reactive oxygen species and nitric oxide, which are involved in neurodegenerative disorders. The mechanism of action for 2-Hydroxybenzimidazole involves the formation of hydrogen bonds with hydroxyl groups on proteins. It also has been shown to reduce locomotor activity and increase sleep time in mice, which may be due to inhibition of acetylcholine release from cholinergic neurons.</p>Formule :C7H6N2ODegré de pureté :Min. 97.5 Area-%Couleur et forme :Off-White PowderMasse moléculaire :134.14 g/molPantoprazole N-oxide sodium
CAS :<p>Pantoprazole N-oxide sodium is a custom synthesis drug product that is being developed as an impurity standard in the synthesis of Pantoprazole. The compound is also used as a pharmacopoeia analytical standard and a HPLC standard.</p>Formule :C16H15F2N3O5S·NaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :422.36 g/molRabeprazole Impurity 2
CAS :<p>Rabeprazole Impurity 2 is a research and development impurity standard that is used for qualitative analysis. It can be custom synthesized to meet specific needs, and it can also be used in drug product synthesis. Rabeprazole Impurity 2 is a high purity synthetic compound that has been pharmacopoeia-qualified. It can also be used as a metabolite or analytical standard, and it has been studied for its metabolism studies with HPLC-MS. Rabeprazole Impurity 2 has CAS No. 1807988-36-8.</p>Formule :C18H19N3O4Degré de pureté :Min. 95%Masse moléculaire :341.36 g/mol2-Hydroxy-2,2-bis(2-thienyl) acetic acid
CAS :<p>2-Hydroxy-2,2-bis(2-thienyl) acetic acid is a long-acting bronchodilator that can be administered by inhalation. It has been used in the clinical development of medicines for the treatment of asthma and chronic obstructive pulmonary disease. 2-Hydroxy-2,2-bis(2-thienyl) acetic acid is chemically related to pyridinium compounds. It is a potent inhibitor of muscarinic receptors and has an anticholinergic profile similar to atropine. The safety profile of this drug seems to be favourable in humans with no major side effects reported so far.</p>Formule :C10H8O3S2Degré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :240.3 g/molN-Desmethyl galanthamine
CAS :Produit contrôlé<p>N-Desmethyl galanthamine is a plant alkaloid that is found in the Huperzia serrata plant. It has been shown to have cholinergic activity and calcium binding properties. N-Desmethyl galanthamine inhibits acetylcholinesterase, an enzyme responsible for the breakdown of acetylcholine, which is a neurotransmitter. This inhibition leads to increased levels of acetylcholine, which results in increased neuron stimulation and improved memory function. N-Desmethyl galanthamine also binds to β2 nicotinic receptor sites and blocks the binding of nicotine, leading to decreased nicotine dependence.</p>Formule :C16H19NO3Degré de pureté :Min. 95%Masse moléculaire :273.33 g/molCarbendazim
CAS :<p>Carbendazim is a fungicide that inhibits the growth of fungi and bacteria. It has been shown to be potent inducers of polymerase chain reaction (PCR) amplification, with a rate constant of 0.0103 per minute. Carbendazim also has a significant effect on electrochemical impedance spectroscopy (EIS). The EIS analysis was used to compare carbendazim-treated cells with untreated cells, which showed that carbendazim causes an increase in the resistance across the cell membrane. This research suggests that carbendazim may be genotoxic, as it increased the amount of DNA damage observed in wild-type strains and altered the optical properties of DNA. Carbendazim is also an effective inhibitor of nitrite ion oxidation and colloidal gold deposition, which has led to its use as a water vapor control agent for plants.</p>Formule :C9H9N3O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :191.19 g/mol6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5(2H,4H)-dione
CAS :<p>6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5(2H,4H)-dione is a chlorinating agent that converts alcohols to alkyl chlorides. It is used for the conversion of diazotizable aromatic compounds to diazo compounds. This compound has been shown to be neuroprotective in animal models and provides protection against glutamate excitotoxicity. 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5(2H,4H)-dione also reacts with nitrite ions to form the corresponding nitroso derivatives. These derivatives can cause DNA damage and are mutagenic. 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5(2H,4H)-dione has been shown to react with aminoguanidine to produce a chromat</p>Formule :C9H5Cl2N3O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :258.06 g/mol
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