Dérivés du Benzimidazole et de l’Imidazole
Le benzimidazole est un composé constitué d’un noyau benzénique fusionné à un noyau imidazole, une structure à cinq membres contenant deux atomes d’azote. Les dérivés du benzimidazole, comme l’albendazole, sont connus pour leur activité antiparasitaire et antifongique, utilisés dans le traitement des infections parasitaires et de certaines maladies parasitaires chez les animaux et les humains. L’imidazole, quant à lui, est une structure à cinq membres avec deux atomes d’azote, présente dans divers composés biologiquement actifs. Les dérivés de l’imidazole, comme le métronidazole, possèdent des propriétés antimicrobiennes et antiparasitaires. Ces composés sont également utilisés dans l’industrie pharmaceutique pour le traitement des infections bactériennes, des maladies parasitaires et de certaines infections fongiques, ainsi qu’en chimie organique comme catalyseurs.
Chez CymitQuimica, nous proposons des benzimidazoles et des imidazoles de haute pureté pour la recherche en chimie médicinale, pharmacologie et biotechnologie.
10376 produits trouvés pour "Dérivés du Benzimidazole et de l’Imidazole"
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N-Desalkyl itraconazole
CAS :<p>N-Desalkyl itraconazole is a triazole antifungal drug that belongs to the group of medicines. It is used in the treatment of systemic mycoses, including blastomycosis and histoplasmosis. N-Desalkyl itraconazole has been shown to inhibit the growth of fungi by interfering with their cell membranes and inhibiting their production of ergosterol. Calibration studies have shown that this drug binds to human liver microsomes and plasma proteins, as well as transporters such as P-glycoprotein. These interactions may influence its pharmacokinetics, which can be determined using a bioanalytical method.</p>Formule :C31H30Cl2N8O4Degré de pureté :Min. 95%Masse moléculaire :649.53 g/mol(1R,3S,5S)-3-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8,8-dimethyl-8-azabicyclo[3.2.1]oct-6-en bromide
CAS :<p>The human red blood cell (RBC) is a non-nucleated cell in the human blood that carries oxygen to the body's cells. The erythrocyte is characterized by its biconcave shape and its lack of organelles. It has a volume of about 80 fL, and a diameter of about 7 micrometers. The RBCs are produced in bone marrow from precursor cells that differentiate into erythroid progenitor cells. This drug binds to the hemoglobin molecules in the red blood cells and alters their shape, causing an increase in their deformability. In addition, this drug decreases the viscosity of the plasma outside of the red blood cell, which increases its extravascular sensitivity. Evaluations have been performed on low doses to evaluate sensitivities within capillaries with microscopy parameters such as magnification and resolution. These evaluations have shown that this drug can be used for quantifying changes in capillary size due to low doses (</p>Formule :C19H22NO3S2·BrDegré de pureté :Min. 95%Masse moléculaire :456.42 g/molSolifenacin Impurity D
CAS :<p>Solifenacin Impurity D is a synthetic impurity of solifenacin. Solifenacin is an anti-cholinergic drug used to treat overactive bladder and urinary incontinence. The purity of this product is 99%. It is soluble in methanol, ethanol, chloroform, and acetone. Solifenacin Impurity D can be used as a reference material for analytical purposes or as an impurity standard in the development of new drugs.</p>Formule :C31H28N2ODegré de pureté :Min. 96 Area-%Couleur et forme :White PowderMasse moléculaire :444.57 g/mol2-Methoxy-5-methyl-γ-phenylbenzenepropanol
CAS :<p>2-Methoxy-5-methyl-gamma-phenylbenzenepropanol is a synthetic compound that is used as an intermediate in the synthesis of coumarin derivatives. Reaction with sulfonating agents produces sulfones, and reaction with borohydride reagents produces boronates. The synthesis of 2-methoxy-5-methyl-gamma-phenylbenzenepropanol can be accomplished by the reduction of diphenyl ethers with lithium aluminum hydride or borohydride. The reduction can also be carried out using lanthanum oxide and potassium borohydride. The reaction proceeds smoothly at room temperature in nonpolar solvents.<br>2-Methoxy-5-methyl-gamma-phenylbenzenepropanol reacts with chloride to produce the corresponding chlorides, which are useful intermediates for the synthesis of tolterodine tartrate, a drug used to treat urinary inc</p>Formule :C17H20O2Degré de pureté :Min. 95%Masse moléculaire :256.34 g/molDehydrodeoxy donepezil
CAS :<p>Dehydrodeoxy donepezil is an analytical standard that is used in the manufacture of pharmaceuticals. It is a synthetic drug impurity, and its CAS number is 120013-45-8. Dehydrodeoxy donepezil can be found in the API impurity grade of various drugs, including those that are manufactured by Custom synthesis and natural synthesis. The pharmacopoeia states that dehydrodeoxy donepezil has a purity level of 98% or greater. This product can also be found as a metabolite in humans, with its half-life being approximately 40 minutes.</p>Formule :C24H29NO2Degré de pureté :Min. 95%Masse moléculaire :363.49 g/molEthyl (S)-1-phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate
CAS :<p>Ethyl (S)-1-phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate is an analytical standard used to identify impurities in drug products. It is a metabolite of the drug product and has been shown to be safe for human consumption. The compound is a synthetic chemical that is not found naturally in the environment. CAS No. 180468-42-2</p>Formule :C18H19NO2Degré de pureté :Min. 95%Masse moléculaire :281.35 g/molZolazepam
CAS :<p>Zolazepam (CI 716), a pyrazole and diazazone derivative, is a benzodiazepine-like veterinary anesthetic.</p>Formule :C15H15FN4OCouleur et forme :SolidMasse moléculaire :286.3(S)-4-(2-Methylpropyl)-2-pyrrolidinone
CAS :Produit contrôlé<p>(S)-4-(2-Methylpropyl)-2-pyrrolidinone is a lactam that has been synthesized in the laboratory. It is an organic solvent that is used in the synthesis of other compounds. The compound has a potential for producing impurities, such as isopropyl and phosphite, during synthesis. (S)-4-(2-Methylpropyl)-2-pyrrolidinone can be synthesized by reacting 2-methylpropionic acid with one equivalent of methylamine. This reaction takes place in an organic solvent and requires kinetic control to avoid side reactions.</p>Formule :C8H15NODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :141.21 g/molAbeprazan
CAS :<p>Abeprazan is a potassium-competitive acid blocker targeting acid-related diseases without acid activation.</p>Formule :C19H17F3N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :410.41(R,R)-Glycopyrrolate
CAS :<p>(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities.</p>Formule :C19H28BrNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.34Omeprazole Sodium
CAS :Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Formule :C17H18N3NaO3SDegré de pureté :99.84%Couleur et forme :Clear In WaterMasse moléculaire :367.4Metopimazine
CAS :<p>Metopimazine is a selective and peripherally restricted dopamine D3 and D2 receptors antagonist.</p>Formule :C22H27N3O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.6Prochloraz
CAS :Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.Formule :C15H16Cl3N3O2Degré de pureté :99.75% - 99.79%Couleur et forme :Colorless SolidMasse moléculaire :376.67Isopropyl 2-hydroxy-2-phenylacetate
CAS :<p>Isopropyl 2-hydroxy-2-phenylacetate is an inorganic acid that is used as a solvent and as a reagent for sample preparation. It has been shown to be able to dissolve hydroxy methyl cellulose, which is a common component of membranes. In addition, it can be used as an electrospray ionization source and has been shown to have a phase transition temperature of -24 degrees Celsius. Isopropyl 2-hydroxy-2-phenylacetate has also been shown to inhibit the action of cholic acid on kinetics in high-performance liquid chromatography. This chemical compound also contains an ethyl group, which may be due to its derivation from acetone.</p>Formule :C11H14O3Degré de pureté :Min. 95%Masse moléculaire :194.23 g/mol(S)-Rabeprazole sodium
CAS :<p>(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.</p>Formule :C18H21N3O3S•NaDegré de pureté :Min. 95%Masse moléculaire :382.43 g/mol5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone
CAS :<p>5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is a hydroxide that is obtained by the reflux of 4-hydroxybenzaldehyde with an alkali metal hydroxide. It can be used in the synthesis of benzylated donepezil hydrochloride. 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone condenses with pyridinecarboxaldehyde to produce 1-(4'-pyridylmethylene)indane. This reaction produces a mixture of products, including benzoic acid and the indane derivative.</p>Formule :C17H15NO3Degré de pureté :Min. 95%Masse moléculaire :281.31 g/mol(1-Nitroethyl)benzene
CAS :<p>(1-Nitroethyl)benzene is a chloride that belongs to the family of muscarinic receptor antagonists. Its amide form is used in medicine as an antiviral agent, and it has been shown to be effective against HIV. (1-Nitroethyl)benzene also binds to the adenosine A3 receptor, which inhibits autoimmune diseases by preventing the proliferation of lymphocytes. The nitro group on this molecule can undergo a number of chemical reactions, including addition with alkylsulfonyl chloride or nitration with nitric acid.</p>Formule :C8H9NO2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :151.16 g/molTroriluzole
CAS :<p>Troriluzole is a glutamate modulator with anticancer activity and is used in the study of spinocerebellar ataxia.</p>Formule :C15H16F3N5O4SDegré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :419.38Pantoprazole sulphide
CAS :<p>Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.</p>Formule :C16H15F2N3O3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :367.37 g/molMorinidazole
CAS :<p>Morinidazole has antibacterial properties for researching anaerobic infections like appendicitis and PID.</p>Formule :C11H18N4O4Degré de pureté :98.92% - 99.82%Couleur et forme :SolidMasse moléculaire :270.29Pregabalin CV
CAS :Produit contrôléAmino-acids and their esters other than those containing more than one kind of oxygen function, excluding aromatic amino-acids, nesoiFormule :C8H17NO2Couleur et forme :Off-White PowderMasse moléculaire :159.12593Orphenadrine
CAS :<p>Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner,</p>Formule :C18H23NODegré de pureté :98.91% - 99.11%Couleur et forme :SolidMasse moléculaire :269.38L-163491
CAS :<p>L-163491: partial agonist at angiotensin II receptor type 1, less so at type 2, used in research, may treat viral lung inflammation.</p>Formule :C36H40N4O5SCouleur et forme :SolidMasse moléculaire :640.79Aclidinium
CAS :<p>Aclidinium, a dual-action compound, serves as a long-acting muscarinic antagonist and a β2-adrenoceptor (β2-AR) agonist, exhibiting bronchodilator properties. It effectively reduces lung hyperinflation, enhances lung function, and prolongs exercise endurance time. This compound is commonly utilized in studies focusing on chronic obstructive pulmonary disease (COPD).</p>Formule :C26H30NO4S2Couleur et forme :SolidMasse moléculaire :484.65rac-4,5-Dehydropregabalin (3-(aminomethyl)-5-methylhex-4-enoic acid)
CAS :Amino-acids and their esters other than those containing more than one kind of oxygen function, excluding aromatic amino-acids, nesoiFormule :C8H15NO2Couleur et forme :Off-White SolidMasse moléculaire :157.11028Desmethoxy Omeprazole (2-(((3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole; 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole) (DISCONTINUED)
CAS :Compounds containing an unfused pyridine ring in the structure, nesoiFormule :C16H17N3O2SCouleur et forme :White Off-White SolidMasse moléculaire :315.10415Donepezil Quaternary Salt (Donepezilbenzyl Bromide) (1,1-dibenzyl-4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)piperidin-1-ium, bromide; 1,1-dibenzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidinium, bromide)
CAS :Compounds containing an unfused pyridine ring in the structure, nesoiFormule :C31H36BrNO3Couleur et forme :White Off-White SolidMasse moléculaire :550.53Solifenacin Related Compound 17 (Dimethyl Carbonate)
CAS :Formule :C3H6O3Couleur et forme :Colorless LiquidMasse moléculaire :90.08Isavuconazole Impurity 20 Chloride HCl (Mixture of Diastereomers)
CAS :Formule :C32H30F2N7O4S·Cl·HClCouleur et forme :Off-White SolidMasse moléculaire :646.69 35.45 36.46Carbamazepine EP Impurity D (Carbamazepine USP Related Compound B, Iminostilbene)
CAS :Formule :C14H11NCouleur et forme :Yellow SolidMasse moléculaire :193.25Dextromethorphan EP Impurity D
CAS :Formule :C18H25NOCouleur et forme :Colorless OilMasse moléculaire :271.40Pregabalin Lactose Conjugate Impurity
Formule :C20H35NO11Couleur et forme :Off-White SolidMasse moléculaire :465.50Pregabalin Impurity PD0310887
CAS :Formule :C14H25NO6Couleur et forme :White To Off-White SolidMasse moléculaire :303.36Vonoprazan Impurity 76
CAS :Formule :C22H15F2N3Couleur et forme :Yellow SolidMasse moléculaire :359.38Vonoprazan Impurity 7
CAS :Formule :C17H20FN3O2SCouleur et forme :White To Off-White SolidMasse moléculaire :349.43N-Nitroso (R)-Lansoprazole (N-Nitroso Dexlansoprazole)
Formule :C16H13F3N4O3SMasse moléculaire :398.36Fesoterodine Impurity 20
CAS :Formule :C22H29NOCouleur et forme :White To Off-White SolidMasse moléculaire :323.48tert-Butyl 5-((2-(3-Hydroxyphenyl)quinazolin-4-yl)amino)-1H-Indazole-1-Carboxylate
Formule :C26H23N5O3Masse moléculaire :453.50Ethyl 5-Methyl-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate
CAS :Couleur et forme :SolidMasse moléculaire :170.167999267578121-methyl-1H-benzimidazole-2-sulfonic acid
CAS :Degré de pureté :95.0%Masse moléculaire :212.22000122070312(S)-5-(HYDROXYMETHYL)-3-METHYLOXAZOLIDIN-2-ONE
CAS :Degré de pureté :95.0%Masse moléculaire :131.130996704101562-Piperazin-1-yl-1H-benzoimidazole
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :202.26100158691406(1,2,4-Triazol-4-yl) Itraconazole
CAS :Produit contrôlé<p>Impurity Itraconazole EP Impurity B<br>Applications (1,2,4-Triazol-4-yl) Itraconazole (Itraconazole EP Impurity B) is an isomer of Itraconazole. It is a COVID19-related research product.<br></p>Formule :C35H38Cl2N8O4Couleur et forme :Off White SolidMasse moléculaire :705.63(7-Chloro-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine Dimaleate
CAS :Produit contrôléFormule :C16H16ClN3•2(C4H4O4)Couleur et forme :NeatMasse moléculaire :401.11423
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