Dérivés du Benzimidazole et de l’Imidazole
Le benzimidazole est un composé constitué d’un noyau benzénique fusionné à un noyau imidazole, une structure à cinq membres contenant deux atomes d’azote. Les dérivés du benzimidazole, comme l’albendazole, sont connus pour leur activité antiparasitaire et antifongique, utilisés dans le traitement des infections parasitaires et de certaines maladies parasitaires chez les animaux et les humains. L’imidazole, quant à lui, est une structure à cinq membres avec deux atomes d’azote, présente dans divers composés biologiquement actifs. Les dérivés de l’imidazole, comme le métronidazole, possèdent des propriétés antimicrobiennes et antiparasitaires. Ces composés sont également utilisés dans l’industrie pharmaceutique pour le traitement des infections bactériennes, des maladies parasitaires et de certaines infections fongiques, ainsi qu’en chimie organique comme catalyseurs.
Chez CymitQuimica, nous proposons des benzimidazoles et des imidazoles de haute pureté pour la recherche en chimie médicinale, pharmacologie et biotechnologie.
10375 produits trouvés pour "Dérivés du Benzimidazole et de l’Imidazole"
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N-Desalkyl itraconazole
CAS :<p>N-Desalkyl itraconazole is a triazole antifungal drug that belongs to the group of medicines. It is used in the treatment of systemic mycoses, including blastomycosis and histoplasmosis. N-Desalkyl itraconazole has been shown to inhibit the growth of fungi by interfering with their cell membranes and inhibiting their production of ergosterol. Calibration studies have shown that this drug binds to human liver microsomes and plasma proteins, as well as transporters such as P-glycoprotein. These interactions may influence its pharmacokinetics, which can be determined using a bioanalytical method.</p>Formule :C31H30Cl2N8O4Degré de pureté :Min. 95%Masse moléculaire :649.53 g/mol1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole
CAS :<p>1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole is an impurity of a drug product. It is a metabolite that has been shown to be present in human plasma and urine. This compound is synthetically produced and is not found in nature. It has been shown to have niche applications in both analytical chemistry and pharmacopoeia.</p>Formule :C25H22F6N4O3SDegré de pureté :Min. 95%Masse moléculaire :572.52 g/mol6-Methyl-4-phenyl-3,4-dihydro-1-benzopyran-2-one
CAS :<p>6-Methyl-4-phenyl-3,4-dihydro-1-benzopyran-2-one is an analog of the natural product zearalenone, which can be used as an acid catalyst for the synthesis of various pharmaceuticals. It has a linear range and is structurally similar to a number of other analogs. The chloride ion is involved in the optimization of the extraction parameters and can be replaced by other c1-4 alkyl groups. 6-Methyl-4-phenyl-3,4-dihydro-1 -benzopyran 2 one is typically prepared using a preparative high performance liquid chromatography technique that involves dehydration.</p>Formule :C16H14O2Degré de pureté :Min. 95%Masse moléculaire :238.28 g/mol4-Methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol
CAS :<p>4-Methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol is a synthetic impurity standard that is used in the synthesis of drug products. This compound is also known as 4-methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol and has a CAS number of 480432-14-2. It is used to verify the purity of drugs and drug products. 4MMPP can be found in pharmacopoeia, drug development, and metabolite studies. This compound is a research and development product for niche markets. 4MMPP can be obtained through custom synthesis or by synthesis.</p>Formule :C19H25NODegré de pureté :Min. 95%Masse moléculaire :283.41 g/molAlbendazole sulfone
CAS :<p>Albendazole sulfone is a metabolite of the drug albendazole. It is used as an analytical standard to measure the concentration of albendazole in human plasma and urine samples. The concentration-time curve for albendazole sulfone can be determined using a nonlinear regression analysis, with the rate constant being calculated from the slope and intercept. This method has been shown to be accurate for predicting pharmacokinetic parameters in humans. Albendazole sulfone is also used as a probe in wastewater treatment studies, where it binds to colloidal gold particles that are used to visualize the removal of small particles by microorganisms.</p>Formule :C12H15N3O4SDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :297.33 g/mol(S)-4-(2-Methylpropyl)-2-pyrrolidinone
CAS :Produit contrôlé<p>(S)-4-(2-Methylpropyl)-2-pyrrolidinone is a lactam that has been synthesized in the laboratory. It is an organic solvent that is used in the synthesis of other compounds. The compound has a potential for producing impurities, such as isopropyl and phosphite, during synthesis. (S)-4-(2-Methylpropyl)-2-pyrrolidinone can be synthesized by reacting 2-methylpropionic acid with one equivalent of methylamine. This reaction takes place in an organic solvent and requires kinetic control to avoid side reactions.</p>Formule :C8H15NODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :141.21 g/mol(R,R)-Glycopyrrolate
CAS :<p>(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities.</p>Formule :C19H28BrNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.34Zolazepam
CAS :<p>Zolazepam (CI 716), a pyrazole and diazazone derivative, is a benzodiazepine-like veterinary anesthetic.</p>Formule :C15H15FN4OCouleur et forme :SolidMasse moléculaire :286.3Metopimazine
CAS :<p>Metopimazine is a selective and peripherally restricted dopamine D3 and D2 receptors antagonist.</p>Formule :C22H27N3O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.6Prochloraz
CAS :<p>Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.</p>Formule :C15H16Cl3N3O2Degré de pureté :99.75% - 99.79%Couleur et forme :Colorless SolidMasse moléculaire :376.67Omeprazole Sodium
CAS :<p>Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.</p>Formule :C17H18N3NaO3SDegré de pureté :99.84%Couleur et forme :Clear In WaterMasse moléculaire :367.4Abeprazan
CAS :<p>Abeprazan is a potassium-competitive acid blocker targeting acid-related diseases without acid activation.</p>Formule :C19H17F3N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :410.41Morinidazole
CAS :<p>Morinidazole has antibacterial properties for researching anaerobic infections like appendicitis and PID.</p>Formule :C11H18N4O4Degré de pureté :98.92% - 99.82%Couleur et forme :SolidMasse moléculaire :270.29Orphenadrine
CAS :<p>Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner,</p>Formule :C18H23NODegré de pureté :98.91% - 99.11%Couleur et forme :SolidMasse moléculaire :269.385,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone
CAS :<p>5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is a hydroxide that is obtained by the reflux of 4-hydroxybenzaldehyde with an alkali metal hydroxide. It can be used in the synthesis of benzylated donepezil hydrochloride. 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone condenses with pyridinecarboxaldehyde to produce 1-(4'-pyridylmethylene)indane. This reaction produces a mixture of products, including benzoic acid and the indane derivative.</p>Formule :C17H15NO3Degré de pureté :Min. 95%Masse moléculaire :281.31 g/molIsopropyl 2-hydroxy-2-phenylacetate
CAS :<p>Isopropyl 2-hydroxy-2-phenylacetate is an inorganic acid that is used as a solvent and as a reagent for sample preparation. It has been shown to be able to dissolve hydroxy methyl cellulose, which is a common component of membranes. In addition, it can be used as an electrospray ionization source and has been shown to have a phase transition temperature of -24 degrees Celsius. Isopropyl 2-hydroxy-2-phenylacetate has also been shown to inhibit the action of cholic acid on kinetics in high-performance liquid chromatography. This chemical compound also contains an ethyl group, which may be due to its derivation from acetone.</p>Formule :C11H14O3Degré de pureté :Min. 95%Masse moléculaire :194.23 g/mol(1-Nitroethyl)benzene
CAS :<p>(1-Nitroethyl)benzene is a chloride that belongs to the family of muscarinic receptor antagonists. Its amide form is used in medicine as an antiviral agent, and it has been shown to be effective against HIV. (1-Nitroethyl)benzene also binds to the adenosine A3 receptor, which inhibits autoimmune diseases by preventing the proliferation of lymphocytes. The nitro group on this molecule can undergo a number of chemical reactions, including addition with alkylsulfonyl chloride or nitration with nitric acid.</p>Formule :C8H9NO2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :151.16 g/molTroriluzole
CAS :<p>Troriluzole is a glutamate modulator with anticancer activity and is used in the study of spinocerebellar ataxia.</p>Formule :C15H16F3N5O4SDegré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :419.38(S)-Rabeprazole sodium
CAS :<p>(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.</p>Formule :C18H21N3O3S•NaDegré de pureté :Min. 95%Masse moléculaire :382.43 g/molPregabalin CV
CAS :Produit contrôléAmino-acids and their esters other than those containing more than one kind of oxygen function, excluding aromatic amino-acids, nesoiFormule :C8H17NO2Couleur et forme :Off-White PowderMasse moléculaire :159.23Pantoprazole sulphide
CAS :<p>Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.</p>Formule :C16H15F2N3O3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :367.37 g/molL-163491
CAS :<p>L-163491: partial agonist at angiotensin II receptor type 1, less so at type 2, used in research, may treat viral lung inflammation.</p>Formule :C36H40N4O5SCouleur et forme :SolidMasse moléculaire :640.79Aclidinium
CAS :<p>Aclidinium, a dual-action compound, serves as a long-acting muscarinic antagonist and a β2-adrenoceptor (β2-AR) agonist, exhibiting bronchodilator properties. It effectively reduces lung hyperinflation, enhances lung function, and prolongs exercise endurance time. This compound is commonly utilized in studies focusing on chronic obstructive pulmonary disease (COPD).</p>Formule :C26H30NO4S2Couleur et forme :SolidMasse moléculaire :484.65Donepezil Quaternary Salt (Donepezilbenzyl Bromide) (1,1-dibenzyl-4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)piperidin-1-ium, bromide; 1,1-dibenzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidinium, bromide)
CAS :Compounds containing an unfused pyridine ring in the structure, nesoiFormule :C31H36BrNO3Couleur et forme :White Off-White SolidMasse moléculaire :549.18786rac-4,5-Dehydropregabalin (3-(aminomethyl)-5-methylhex-4-enoic acid)
CAS :Amino-acids and their esters other than those containing more than one kind of oxygen function, excluding aromatic amino-acids, nesoiFormule :C8H15NO2Couleur et forme :Off-White SolidMasse moléculaire :157.21Desmethoxy Omeprazole (2-(((3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole; 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole) (DISCONTINUED)
CAS :Compounds containing an unfused pyridine ring in the structure, nesoiFormule :C16H17N3O2SCouleur et forme :White Off-White SolidMasse moléculaire :315.10415N-Nitroso (R)-Lansoprazole (N-Nitroso Dexlansoprazole)
Formule :C16H13F3N4O3SMasse moléculaire :398.36Dextromethorphan EP Impurity D
CAS :Formule :C18H25NOCouleur et forme :Colorless OilMasse moléculaire :271.40Pregabalin Lactose Conjugate Impurity
Formule :C20H35NO11Couleur et forme :Off-White SolidMasse moléculaire :465.50Fesoterodine Impurity 20
CAS :Formule :C22H29NOCouleur et forme :White To Off-White SolidMasse moléculaire :323.48Vonoprazan Impurity 7
CAS :Formule :C17H20FN3O2SCouleur et forme :White To Off-White SolidMasse moléculaire :349.43Isavuconazole Impurity 20 Chloride HCl (Mixture of Diastereomers)
CAS :Formule :C32H30F2N7O4S·Cl·HClCouleur et forme :Off-White SolidMasse moléculaire :646.69 35.45 36.46Pregabalin Impurity PD0310887
CAS :Formule :C14H25NO6Couleur et forme :White To Off-White SolidMasse moléculaire :303.36Vonoprazan Impurity 76
CAS :Formule :C22H15F2N3Couleur et forme :Yellow SolidMasse moléculaire :359.38Solifenacin Related Compound 17 (Dimethyl Carbonate)
CAS :Formule :C3H6O3Couleur et forme :Colorless LiquidMasse moléculaire :90.08Carbamazepine EP Impurity D (Carbamazepine USP Related Compound B, Iminostilbene)
CAS :Formule :C14H11NCouleur et forme :Yellow SolidMasse moléculaire :193.25tert-Butyl 5-((2-(3-Hydroxyphenyl)quinazolin-4-yl)amino)-1H-Indazole-1-Carboxylate
Formule :C26H23N5O3Masse moléculaire :453.502-Piperazin-1-yl-1H-benzoimidazole
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :202.261001586914061-methyl-1H-benzimidazole-2-sulfonic acid
CAS :Degré de pureté :95.0%Masse moléculaire :212.22000122070312Ethyl 5-Methyl-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate
CAS :Couleur et forme :SolidMasse moléculaire :170.16799926757812(S)-5-(HYDROXYMETHYL)-3-METHYLOXAZOLIDIN-2-ONE
CAS :Degré de pureté :95.0%Masse moléculaire :131.13099670410156(7-Chloro-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine Dimaleate
CAS :Produit contrôléFormule :C16H16ClN3•2(C4H4O4)Couleur et forme :NeatMasse moléculaire :401.11423(1,2,4-Triazol-4-yl) Itraconazole
CAS :Produit contrôlé<p>Impurity Itraconazole EP Impurity B<br>Applications (1,2,4-Triazol-4-yl) Itraconazole (Itraconazole EP Impurity B) is an isomer of Itraconazole. It is a COVID19-related research product.<br></p>Formule :C35H38Cl2N8O4Couleur et forme :Off White SolidMasse moléculaire :705.63
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